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Items: 8

1.

Reciprocal regulation of the Il9 locus by counteracting activities of transcription factors IRF1 and IRF4.

Campos Carrascosa L, Klein M, Kitagawa Y, Lückel C, Marini F, König A, Guralnik A, Raifer H, Hagner-Benes S, Rädler D, Böck A, Kang C, Lohoff M, Garn H, Schaub B, Berberich-Siebelt F, Sakaguchi S, Bopp T, Huber M.

Nat Commun. 2017 May 12;8:15366. doi: 10.1038/ncomms15366.

2.

The transcription factor Interferon Regulatory Factor 4 is required for the generation of protective effector CD8+ T cells.

Raczkowski F, Ritter J, Heesch K, Schumacher V, Guralnik A, Höcker L, Raifer H, Klein M, Bopp T, Harb H, Kesper DA, Pfefferle PI, Grusdat M, Lang PA, Mittrücker HW, Huber M.

Proc Natl Acad Sci U S A. 2013 Sep 10;110(37):15019-24. doi: 10.1073/pnas.1309378110. Epub 2013 Aug 26.

3.

Tc9 cells, a new subset of CD8(+) T cells, support Th2-mediated airway inflammation.

Visekruna A, Ritter J, Scholz T, Campos L, Guralnik A, Poncette L, Raifer H, Hagner S, Garn H, Staudt V, Bopp T, Reuter S, Taube C, Loser K, Huber M.

Eur J Immunol. 2013 Mar;43(3):606-18. doi: 10.1002/eji.201242825. Epub 2013 Jan 31.

4.

IL-17A secretion by CD8+ T cells supports Th17-mediated autoimmune encephalomyelitis.

Huber M, Heink S, Pagenstecher A, Reinhard K, Ritter J, Visekruna A, Guralnik A, Bollig N, Jeltsch K, Heinemann C, Wittmann E, Buch T, Prazeres da Costa O, Brüstle A, Brenner D, Mak TW, Mittrücker HW, Tackenberg B, Kamradt T, Lohoff M.

J Clin Invest. 2013 Jan;123(1):247-60. doi: 10.1172/JCI63681. Epub 2012 Dec 10.

5.

Unlike αβ T cells, γδ T cells, LTi cells and NKT cells do not require IRF4 for the production of IL-17A and IL-22.

Raifer H, Mahiny AJ, Bollig N, Petermann F, Hellhund A, Kellner K, Guralnik A, Reinhard K, Bothur E, Huber M, Bauer S, Löhning M, Kiss EA, Ganal SC, Diefenbach A, Korn T, Lohoff M.

Eur J Immunol. 2012 Dec;42(12):3189-201. doi: 10.1002/eji.201142155. Epub 2012 Oct 17.

6.

A Th17-like developmental process leads to CD8(+) Tc17 cells with reduced cytotoxic activity.

Huber M, Heink S, Grothe H, Guralnik A, Reinhard K, Elflein K, Hünig T, Mittrücker HW, Brüstle A, Kamradt T, Lohoff M.

Eur J Immunol. 2009 Jul;39(7):1716-25. doi: 10.1002/eji.200939412.

7.

IRF4 is essential for IL-21-mediated induction, amplification, and stabilization of the Th17 phenotype.

Huber M, Brüstle A, Reinhard K, Guralnik A, Walter G, Mahiny A, von Löw E, Lohoff M.

Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20846-51. doi: 10.1073/pnas.0809077106. Epub 2008 Dec 16.

8.

IL-27 inhibits the development of regulatory T cells via STAT3.

Huber M, Steinwald V, Guralnik A, Brüstle A, Kleemann P, Rosenplänter C, Decker T, Lohoff M.

Int Immunol. 2008 Feb;20(2):223-34. Epub 2007 Dec 21.

PMID:
18156621

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