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Items: 1 to 50 of 59

1.

Sex differences in traumatic brain injury: What we know and what we should know.

Gupte R, Brooks WM, Vukas RR, Pierce JD, Harris JL.

J Neurotrauma. 2019 Feb 22. doi: 10.1089/neu.2018.6171. [Epub ahead of print]

PMID:
30794028
2.

The impact of racial and ethnic disparities in inhaled corticosteroid adherence on healthcare expenditures in adults with asthma.

Vaidya V, Gabriel MH, Patel P, Gupte R, James C.

Curr Med Res Opin. 2019 Feb 22:1. doi: 10.1080/03007995.2019.1586221. [Epub ahead of print]

PMID:
30793988
3.

Evaluation of taurine neuroprotection in aged rats with traumatic brain injury.

Gupte R, Christian S, Keselman P, Habiger J, Brooks WM, Harris JL.

Brain Imaging Behav. 2018 Apr 14. doi: 10.1007/s11682-018-9865-5. [Epub ahead of print]

PMID:
29656312
4.

Rare Cell Detection by Single-Cell RNA Sequencing as Guided by Single-Molecule RNA FISH.

Torre E, Dueck H, Shaffer S, Gospocic J, Gupte R, Bonasio R, Kim J, Murray J, Raj A.

Cell Syst. 2018 Feb 28;6(2):171-179.e5. doi: 10.1016/j.cels.2018.01.014. Epub 2018 Feb 14.

5.

Ubiquinol treatment for TBI in male rats: Effects on mitochondrial integrity, injury severity, and neurometabolism.

Pierce JD, Gupte R, Thimmesch A, Shen Q, Hiebert JB, Brooks WM, Clancy RL, Diaz FJ, Harris JL.

J Neurosci Res. 2018 Jun;96(6):1080-1092. doi: 10.1002/jnr.24210. Epub 2018 Jan 30.

PMID:
29380912
6.

Visualizing adenosine-to-inosine RNA editing in single mammalian cells.

Mellis IA, Gupte R, Raj A, Rouhanifard SH.

Nat Methods. 2017 Aug;14(8):801-804. doi: 10.1038/nmeth.4332. Epub 2017 Jun 12.

7.

PARPs and ADP-ribosylation: recent advances linking molecular functions to biological outcomes.

Gupte R, Liu Z, Kraus WL.

Genes Dev. 2017 Jan 15;31(2):101-126. doi: 10.1101/gad.291518.116. Review.

8.

PARP-1 Controls the Adipogenic Transcriptional Program by PARylating C/EBPβ and Modulating Its Transcriptional Activity.

Luo X, Ryu KW, Kim DS, Nandu T, Medina CJ, Gupte R, Gibson BA, Soccio RE, Yu Y, Gupta RK, Kraus WL.

Mol Cell. 2017 Jan 19;65(2):260-271. doi: 10.1016/j.molcel.2016.11.015.

9.

Paraffin processing of stented arteries using a postfixation dissolution of metallic and polymeric stents.

Fishbein I, Welch T, Guerrero DT, Alferiev IS, Adamo RF, Chorny M, Gupte RK, Tang Y, Levy RJ.

Cardiovasc Pathol. 2016 Nov - Dec;25(6):483-488. doi: 10.1016/j.carpath.2016.08.002. Epub 2016 Aug 20.

10.

Vascular smooth muscle cell contractile protein expression is increased through protein kinase G-dependent and -independent pathways by glucose-6-phosphate dehydrogenase inhibition and deficiency.

Chettimada S, Joshi SR, Dhagia V, Aiezza A 2nd, Lincoln TM, Gupte R, Miano JM, Gupte SA.

Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H904-H912. doi: 10.1152/ajpheart.00335.2016. Epub 2016 Aug 12.

11.

A semi-synthetic natural product blocks collagen induced arthritis by preferentially suppressing the production of IL-6.

Kulkarni-Almeida A, Shah M, Jadhav M, Hegde B, Trivedi J, Mishra PD, Mahajan GB, Dadarkar S, Gupte R, Dagia N.

Int Immunopharmacol. 2016 Apr;33:63-9. doi: 10.1016/j.intimp.2016.01.001. Epub 2016 Feb 9.

PMID:
26869203
12.

Convergent phosphomodulation of the major neuronal dendritic potassium channel Kv4.2 by pituitary adenylate cyclase-activating polypeptide.

Gupte RP, Kadunganattil S, Shepherd AJ, Merrill R, Planer W, Bruchas MR, Strack S, Mohapatra DP.

Neuropharmacology. 2016 Feb;101:291-308. doi: 10.1016/j.neuropharm.2015.10.006. Epub 2015 Oct 9.

13.

Hypoxia-induced glucose-6-phosphate dehydrogenase overexpression and -activation in pulmonary artery smooth muscle cells: implication in pulmonary hypertension.

Chettimada S, Gupte R, Rawat D, Gebb SA, McMurtry IF, Gupte SA.

Am J Physiol Lung Cell Mol Physiol. 2015 Feb 1;308(3):L287-300. doi: 10.1152/ajplung.00229.2014. Epub 2014 Dec 5.

14.

Increased reactive oxygen species, metabolic maladaptation, and autophagy contribute to pulmonary arterial hypertension-induced ventricular hypertrophy and diastolic heart failure.

Rawat DK, Alzoubi A, Gupte R, Chettimada S, Watanabe M, Kahn AG, Okada T, McMurtry IF, Gupte SA.

Hypertension. 2014 Dec;64(6):1266-74. doi: 10.1161/HYPERTENSIONAHA.114.03261. Epub 2014 Sep 29.

PMID:
25267798
15.

Glucocorticoid receptor coordinates transcription factor-dominated regulatory network in macrophages.

Chinenov Y, Coppo M, Gupte R, Sacta MA, Rogatsky I.

BMC Genomics. 2014 Aug 6;15:656. doi: 10.1186/1471-2164-15-656.

16.

Glucose-6-phosphate dehydrogenase plays a critical role in hypoxia-induced CD133+ progenitor cells self-renewal and stimulates their accumulation in the lungs of pulmonary hypertensive rats.

Chettimada S, Joshi SR, Alzoubi A, Gebb SA, McMurtry IF, Gupte R, Gupte SA.

Am J Physiol Lung Cell Mol Physiol. 2014 Oct 1;307(7):L545-56. doi: 10.1152/ajplung.00303.2013. Epub 2014 Jul 25.

17.

Pivotal role of NOD2 in inflammatory processes affecting atherosclerosis and periodontal bone loss.

Yuan H, Zelkha S, Burkatovskaya M, Gupte R, Leeman SE, Amar S.

Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):E5059-68. doi: 10.1073/pnas.1320862110. Epub 2013 Dec 9. Erratum in: Proc Natl Acad Sci U S A. 2014 Nov 25;111(47):16973. Zelka, Sami [corrected to Zelkha, Sami].

18.

Glucocorticoid receptor represses proinflammatory genes at distinct steps of the transcription cycle.

Gupte R, Muse GW, Chinenov Y, Adelman K, Rogatsky I.

Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):14616-21. doi: 10.1073/pnas.1309898110. Epub 2013 Aug 15.

19.

Regioselective synthesis of phenanthrenes and evaluation of their anti-oxidant based anti-inflammatory potential.

Kanekar Y, Basha K, Duche S, Gupte R, Kapat A.

Eur J Med Chem. 2013 Sep;67:454-63. doi: 10.1016/j.ejmech.2013.06.016. Epub 2013 Jun 18.

PMID:
23933533
20.

Nuclear receptors in inflammation control: repression by GR and beyond.

Chinenov Y, Gupte R, Rogatsky I.

Mol Cell Endocrinol. 2013 Nov 5;380(1-2):55-64. doi: 10.1016/j.mce.2013.04.006. Epub 2013 Apr 26. Review.

21.

Failure to refill essential prescription medications for asthma among pediatric Medicaid beneficiaries with persistent asthma.

Vaidya V, Gupte R, Balkrishnan R.

Patient Prefer Adherence. 2013;7:21-6. doi: 10.2147/PPA.S37811. Epub 2013 Jan 9.

22.

Distinct modifications in Kv2.1 channel via chemokine receptor CXCR4 regulate neuronal survival-death dynamics.

Shepherd AJ, Loo L, Gupte RP, Mickle AD, Mohapatra DP.

J Neurosci. 2012 Dec 5;32(49):17725-39. doi: 10.1523/JNEUROSCI.3029-12.2012.

23.

Automated microfluidic processing platform for multiplexed magnetic bead immunoassays.

Sasso LA, Johnston IH, Zheng M, Gupte RK, Ündar A, Zahn JD.

Microfluid Nanofluidics. 2012 Oct;13(4):603-612.

24.

Virtual screening for LPA2-specific agonists identifies a nonlipid compound with antiapoptotic actions.

Kiss GN, Fells JI, Gupte R, Lee SC, Liu J, Nusser N, Lim KG, Ray RM, Lin FT, Parrill AL, Sümegi B, Miller DD, Tigyi G.

Mol Pharmacol. 2012 Dec;82(6):1162-73. doi: 10.1124/mol.112.079699. Epub 2012 Sep 11.

25.

Role of transcriptional coregulator GRIP1 in the anti-inflammatory actions of glucocorticoids.

Chinenov Y, Gupte R, Dobrovolna J, Flammer JR, Liu B, Michelassi FE, Rogatsky I.

Proc Natl Acad Sci U S A. 2012 Jul 17;109(29):11776-81. doi: 10.1073/pnas.1206059109. Epub 2012 Jul 2.

26.

Down-regulation of replication factor C-40 (RFC40) causes chromosomal missegregation in neonatal and hypertrophic adult rat cardiac myocytes.

Ata H, Shrestha D, Oka M, Ochi R, Jong CJ, Gebb S, Benjamin J, Schaffer S, Hobart HH, Downey J, McMurtry I, Gupte R.

PLoS One. 2012;7(6):e39009. doi: 10.1371/journal.pone.0039009. Epub 2012 Jun 14.

27.

Controlling cancer through the autotaxin-lysophosphatidic acid receptor axis.

Gotoh M, Fujiwara Y, Yue J, Liu J, Lee S, Fells J, Uchiyama A, Murakami-Murofushi K, Kennel S, Wall J, Patil R, Gupte R, Balazs L, Miller DD, Tigyi GJ.

Biochem Soc Trans. 2012 Feb;40(1):31-6. doi: 10.1042/BST20110608. Review.

28.

Receptor activator of nuclear factor kappa B ligand antagonists inhibit tissue inflammation and bone loss in experimental periodontitis.

Yuan H, Gupte R, Zelkha S, Amar S.

J Clin Periodontol. 2011 Nov;38(11):1029-36. doi: 10.1111/j.1600-051X.2011.01780.x. Epub 2011 Sep 7.

PMID:
22092474
29.

Methamphetamine toxicity and its implications during HIV-1 infection.

Silverstein PS, Shah A, Gupte R, Liu X, Piepho RW, Kumar S, Kumar A.

J Neurovirol. 2011 Oct;17(5):401-15. doi: 10.1007/s13365-011-0043-4. Epub 2011 Jul 23. Review.

30.

A LC-MS/MS method for concurrent determination of nicotine metabolites and role of CYP2A6 in nicotine metabolism in U937 macrophages: implications in oxidative stress in HIV + smokers.

Jin M, Earla R, Shah A, Earla RL, Gupte R, Mitra AK, Kumar A, Kumar S.

J Neuroimmune Pharmacol. 2012 Mar;7(1):289-99. doi: 10.1007/s11481-011-9283-6. Epub 2011 Jun 8.

31.

Benzyl and naphthalene methylphosphonic acid inhibitors of autotaxin with anti-invasive and anti-metastatic activity.

Gupte R, Patil R, Liu J, Wang Y, Lee SC, Fujiwara Y, Fells J, Bolen AL, Emmons-Thompson K, Yates CR, Siddam A, Panupinthu N, Pham TC, Baker DL, Parrill AL, Mills GB, Tigyi G, Miller DD.

ChemMedChem. 2011 May 2;6(5):922-35. doi: 10.1002/cmdc.201000425. Epub 2011 Apr 4.

32.

Synthesis and pharmacological evaluation of the stereoisomers of 3-carba cyclic-phosphatidic acid.

Gupte R, Siddam A, Lu Y, Li W, Fujiwara Y, Panupinthu N, Pham TC, Baker DL, Parrill AL, Gotoh M, Murakami-Murofushi K, Kobayashi S, Mills GB, Tigyi G, Miller DD.

Bioorg Med Chem Lett. 2010 Dec 15;20(24):7525-8. doi: 10.1016/j.bmcl.2010.09.115. Epub 2010 Oct 8.

33.

Role of NAD(P)H oxidase in superoxide generation and endothelial dysfunction in Goto-Kakizaki (GK) rats as a model of nonobese NIDDM.

Gupte S, Labinskyy N, Gupte R, Csiszar A, Ungvari Z, Edwards JG.

PLoS One. 2010 Jul 26;5(7):e11800. doi: 10.1371/journal.pone.0011800.

34.

Glucose-6-phosphate dehydrogenase is a regulator of vascular smooth muscle contraction.

Gupte RS, Ata H, Rawat D, Abe M, Taylor MS, Ochi R, Gupte SA.

Antioxid Redox Signal. 2011 Feb 15;14(4):543-58. doi: 10.1089/ars.2010.3207. Epub 2010 Oct 25.

35.

Activation of glucose-6-phosphate dehydrogenase promotes acute hypoxic pulmonary artery contraction.

Gupte RS, Rawat DK, Chettimada S, Cioffi DL, Wolin MS, Gerthoffer WT, McMurtry IF, Gupte SA.

J Biol Chem. 2010 Jun 18;285(25):19561-71. doi: 10.1074/jbc.M109.092916. Epub 2010 Apr 2.

36.

A preferential p110alpha/gamma PI3K inhibitor attenuates experimental inflammation by suppressing the production of proinflammatory mediators in a NF-kappaB-dependent manner.

Dagia NM, Agarwal G, Kamath DV, Chetrapal-Kunwar A, Gupte RD, Jadhav MG, Dadarkar SS, Trivedi J, Kulkarni-Almeida AA, Kharas F, Fonseca LC, Kumar S, Bhonde MR.

Am J Physiol Cell Physiol. 2010 Apr;298(4):C929-41. doi: 10.1152/ajpcell.00461.2009. Epub 2010 Jan 20.

37.

18F9 (4-(3,6-bis (ethoxycarbonyl)-4,5,6,7-tetrahydrothieno (2,3-c) pyridin-2-ylamino)-4-oxobutanoic acid) enhances insulin-mediated glucose uptake in vitro and exhibits antidiabetic activity in vivo in db/db mice.

Anandharajan R, Sayyed SG, Doshi LS, Dixit P, Chandak PG, Dixit AV, Brahma MK, Deshmukh NJ, Gupte R, Damre A, Suthar J, Padigaru M, Sharma SD, Nemmani KV.

Metabolism. 2009 Oct;58(10):1503-16. doi: 10.1016/j.metabol.2009.04.036. Epub 2009 Jul 15.

38.

Superoxide production by NAD(P)H oxidase and mitochondria is increased in genetically obese and hyperglycemic rat heart and aorta before the development of cardiac dysfunction. The role of glucose-6-phosphate dehydrogenase-derived NADPH.

Serpillon S, Floyd BC, Gupte RS, George S, Kozicky M, Neito V, Recchia F, Stanley W, Wolin MS, Gupte SA.

Am J Physiol Heart Circ Physiol. 2009 Jul;297(1):H153-62. doi: 10.1152/ajpheart.01142.2008. Epub 2009 May 8.

39.

Synthesis and therapeutic evaluation of pyridyl based novel mTOR inhibitors.

Deore V, Yewalkar N, Bhatia D, Desai N, Gupte RD, Dadarkar SS, Jadhav MG, Tannu AA, Bhatt P, Nemmani KV, Vishwakarma RA, Sharma S, Roychowdhury A, Dagia NM, Bhonde MR, Kumar S.

Bioorg Med Chem Lett. 2009 Jun 1;19(11):2949-52. doi: 10.1016/j.bmcl.2009.04.055. Epub 2009 Apr 18.

PMID:
19409777
40.

A fluorinated analog of ISO-1 blocks the recognition and biological function of MIF and is orally efficacious in a murine model of colitis.

Dagia NM, Kamath DV, Bhatt P, Gupte RD, Dadarkar SS, Fonseca L, Agarwal G, Chetrapal-Kunwar A, Balachandran S, Srinivasan S, Bose J, Pari K, B-Rao C, Parkale SS, Gadekar PK, Rodge AH, Mandrekar N, Vishwakarma RA, Sharma S.

Eur J Pharmacol. 2009 Apr 1;607(1-3):201-12. doi: 10.1016/j.ejphar.2009.02.031. Epub 2009 Feb 21.

PMID:
19239912
41.

Synergistic activation of glucose-6-phosphate dehydrogenase and NAD(P)H oxidase by Src kinase elevates superoxide in type 2 diabetic, Zucker fa/fa, rat liver.

Gupte RS, Floyd BC, Kozicky M, George S, Ungvari ZI, Neito V, Wolin MS, Gupte SA.

Free Radic Biol Med. 2009 Aug 1;47(3):219-28. doi: 10.1016/j.freeradbiomed.2009.01.028. Epub 2009 Feb 20.

42.

A novel mTOR inhibitor is efficacious in a murine model of colitis.

Bhonde MR, Gupte RD, Dadarkar SD, Jadhav MG, Tannu AA, Bhatt P, Bhatia DR, Desai NK, Deore V, Yewalkar N, Vishwakarma RA, Sharma S, Kumar S, Dagia NM.

Am J Physiol Gastrointest Liver Physiol. 2008 Dec;295(6):G1237-45. doi: 10.1152/ajpgi.90537.2008. Epub 2008 Oct 16.

43.

The Cys3-Cys4 loop of the hydrophobin EAS is not required for rodlet formation and surface activity.

Kwan AH, Macindoe I, Vukasin PV, Morris VK, Kass I, Gupte R, Mark AE, Templeton MD, Mackay JP, Sunde M.

J Mol Biol. 2008 Oct 10;382(3):708-20. doi: 10.1016/j.jmb.2008.07.034. Epub 2008 Jul 22.

PMID:
18674544
44.

Quantitative chiral analysis of phthaloylglutamic acid and related analogs by a single ratio kinetic method using electrospray ionization and matrix-assisted laser desorption techniques.

Ramagiri S, Gupte R, Rakov I, Yates CR, Miller DD.

Rapid Commun Mass Spectrom. 2008;22(5):639-46. doi: 10.1002/rcm.3405.

PMID:
18247407
45.

Upregulation of glucose-6-phosphate dehydrogenase and NAD(P)H oxidase activity increases oxidative stress in failing human heart.

Gupte RS, Vijay V, Marks B, Levine RJ, Sabbah HN, Wolin MS, Recchia FA, Gupte SA.

J Card Fail. 2007 Aug;13(6):497-506.

PMID:
17675065
46.

Glucose-6-phosphate dehydrogenase-derived NADPH fuels superoxide production in the failing heart.

Gupte SA, Levine RJ, Gupte RS, Young ME, Lionetti V, Labinskyy V, Floyd BC, Ojaimi C, Bellomo M, Wolin MS, Recchia FA.

J Mol Cell Cardiol. 2006 Aug;41(2):340-9. Epub 2006 Jul 7.

PMID:
16828794
47.

Phosphorylation of RIalpha by cyclin-dependent kinase CDK 2/cyclin E modulates the dissociation of the RIalpha-RFC40 complex.

Gupte RS, Traganos F, Darzynkiewicz Z, Lee MY.

Cell Cycle. 2006 Mar;5(6):653-60. Epub 2006 Mar 15.

PMID:
16582606
48.

Cyclic AMP regulates the expression and nuclear translocation of RFC40 in MCF7 cells.

Gupte RS, Sampson V, Traganos F, Darzynkiewicz Z, Lee MY.

Exp Cell Res. 2006 Apr 1;312(6):796-806. Epub 2006 Jan 17.

PMID:
16413017
49.

RIalpha influences cellular proliferation in cancer cells by transporting RFC40 into the nucleus.

Gupte RS, Pozarowski P, Grabarek J, Traganos F, Darzynkiewicz Z, Lee MY.

Cancer Biol Ther. 2005 Apr;4(4):429-37. Epub 2005 Apr 21.

PMID:
15846072

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