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Items: 1 to 50 of 60

1.

Loss of Slug Compromises DNA Damage Repair and Accelerates Stem Cell Aging in Mammary Epithelium.

Gross KM, Zhou W, Breindel JL, Ouyang J, Jin DX, Sokol ES, Gupta PB, Huber K, Zou L, Kuperwasser C.

Cell Rep. 2019 Jul 9;28(2):394-407.e6. doi: 10.1016/j.celrep.2019.06.043.

PMID:
31291576
Free Article
2.

Implementation of a Blood Management Program at a Tertiary Care Hospital: Effect on Transfusion Practices and Clinical Outcomes Among Patients Undergoing Surgery.

Gani F, Cerullo M, Ejaz A, Gupta PB, Demario VM, Johnston FM, Frank SM, Pawlik TM.

Ann Surg. 2019 Jun;269(6):1073-1079. doi: 10.1097/SLA.0000000000002585.

PMID:
31082904
3.

Phenotypic Plasticity: Driver of Cancer Initiation, Progression, and Therapy Resistance.

Gupta PB, Pastushenko I, Skibinski A, Blanpain C, Kuperwasser C.

Cell Stem Cell. 2019 Jan 3;24(1):65-78. doi: 10.1016/j.stem.2018.11.011. Epub 2018 Dec 13. Review.

PMID:
30554963
4.

Loss of function of NF1 is a mechanism of acquired resistance to endocrine therapy in lobular breast cancer.

Sokol ES, Feng YX, Jin DX, Basudan A, Lee AV, Atkinson JM, Chen J, Stephens PJ, Frampton GM, Gupta PB, Ross JS, Chung JH, Oesterreich S, Ali SM, Hartmaier RJ.

Ann Oncol. 2019 Jan 1;30(1):115-123. doi: 10.1093/annonc/mdy497.

5.

Patient Blood Management Program Improves Blood Use and Clinical Outcomes in Orthopedic Surgery.

Gupta PB, DeMario VM, Amin RM, Gehrie EA, Goel R, Lee KHK, Yang WW, Khanuja HS, Sterling RS, Ness PM, Frank SM.

Anesthesiology. 2018 Dec;129(6):1082-1091. doi: 10.1097/ALN.0000000000002397.

PMID:
30124488
6.

BCL11B Drives Human Mammary Stem Cell Self-Renewal In Vitro by Inhibiting Basal Differentiation.

Miller DH, Jin DX, Sokol ES, Cabrera JR, Superville DA, Gorelov RA, Kuperwasser C, Gupta PB.

Stem Cell Reports. 2018 Mar 13;10(3):1131-1145. doi: 10.1016/j.stemcr.2018.01.036. Epub 2018 Mar 1.

7.

Defining the Essential Function of Yeast Hsf1 Reveals a Compact Transcriptional Program for Maintaining Eukaryotic Proteostasis.

Solís EJ, Pandey JP, Zheng X, Jin DX, Gupta PB, Airoldi EM, Pincus D, Denic V.

Mol Cell. 2018 Feb 1;69(3):534. doi: 10.1016/j.molcel.2018.01.021. No abstract available.

8.

Premature polyadenylation of MAGI3 is associated with diminished N6-methyladenosine in its large internal exon.

Ni TK, Elman JS, Jin DX, Gupta PB, Kuperwasser C.

Sci Rep. 2018 Jan 23;8(1):1415. doi: 10.1038/s41598-018-19916-8.

9.

Perceptual training enhances temporal acuity for multisensory speech.

De Niear MA, Gupta PB, Baum SH, Wallace MT.

Neurobiol Learn Mem. 2018 Jan;147:9-17. doi: 10.1016/j.nlm.2017.10.016. Epub 2017 Oct 28.

PMID:
29107704
10.

Implementation of a Blood Management Program at a Tertiary Care Hospital: Effect on Transfusion Practices and Clinical Outcomes Among Patients Undergoing Surgery.

Gani F, Cerullo M, Ejaz A, Gupta PB, Demario VM, Johnston FM, Frank SM, Pawlik TM.

Ann Surg. 2017 Nov 2. doi: 10.1097/SLA.0000000000002585. [Epub ahead of print]

PMID:
29099397
11.

Cancer-specific PERK signaling drives invasion and metastasis through CREB3L1.

Feng YX, Jin DX, Sokol ES, Reinhardt F, Miller DH, Gupta PB.

Nat Commun. 2017 Oct 20;8(1):1079. doi: 10.1038/s41467-017-01052-y.

12.

Blood utilization in revision versus first-time cardiac surgery: an update in the era of patient blood management.

Hensley NB, Kostibas MP, Yang WW, Crawford TC, Mandal K, Gupta PB, Frank SM, Brown CH 4th.

Transfusion. 2018 Jan;58(1):168-175. doi: 10.1111/trf.14361. Epub 2017 Oct 8.

13.

3D Primary Culture Model to Study Human Mammary Development.

Miller DH, Sokol ES, Gupta PB.

Methods Mol Biol. 2017;1612:139-147. doi: 10.1007/978-1-4939-7021-6_10.

PMID:
28634940
14.

SMARCE1 is required for the invasive progression of in situ cancers.

Sokol ES, Feng YX, Jin DX, Tizabi MD, Miller DH, Cohen MA, Sanduja S, Reinhardt F, Pandey J, Superville DA, Jaenisch R, Gupta PB.

Proc Natl Acad Sci U S A. 2017 Apr 18;114(16):4153-4158. doi: 10.1073/pnas.1703931114. Epub 2017 Apr 4.

15.

Cancer cells exhibit clonal diversity in phenotypic plasticity.

Mathis RA, Sokol ES, Gupta PB.

Open Biol. 2017 Feb;7(2). pii: 160283. doi: 10.1098/rsob.160283.

16.

Suppression of 19S proteasome subunits marks emergence of an altered cell state in diverse cancers.

Tsvetkov P, Sokol E, Jin D, Brune Z, Thiru P, Ghandi M, Garraway LA, Gupta PB, Santagata S, Whitesell L, Lindquist S.

Proc Natl Acad Sci U S A. 2017 Jan 10;114(2):382-387. doi: 10.1073/pnas.1619067114. Epub 2016 Dec 27.

17.

Foreign body in the rectum: A challenge for the emergency physician.

Gajjar RA, Gupta PB.

J Family Med Prim Care. 2016 Apr-Jun;5(2):495-497.

18.

Defining the Essential Function of Yeast Hsf1 Reveals a Compact Transcriptional Program for Maintaining Eukaryotic Proteostasis.

Solís EJ, Pandey JP, Zheng X, Jin DX, Gupta PB, Airoldi EM, Pincus D, Denic V.

Mol Cell. 2016 Jul 7;63(1):60-71. doi: 10.1016/j.molcel.2016.05.014. Epub 2016 Jun 16. Erratum in: Mol Cell. 2018 Feb 1;69(3):534.

19.

AMPK promotes tolerance to Ras pathway inhibition by activating autophagy.

Sanduja S, Feng Y, Mathis RA, Sokol ES, Reinhardt F, Halaban R, Gupta PB.

Oncogene. 2016 Oct 6;35(40):5295-5303. doi: 10.1038/onc.2016.70. Epub 2016 Apr 4.

20.

Growth of human breast tissues from patient cells in 3D hydrogel scaffolds.

Sokol ES, Miller DH, Breggia A, Spencer KC, Arendt LM, Gupta PB.

Breast Cancer Res. 2016 Mar 1;18(1):19. doi: 10.1186/s13058-016-0677-5.

21.

An Alternative Approach to Isoganciclovir: A Prominent Impurity in the Antiviral Drug Ganciclovir.

Sundaram DT, Kamat AG, Prabahar KJ, Gupta PB, Venkateswara Rao B, Paul Douglas S.

Sci Pharm. 2014 Nov 11;83(2):233-41. doi: 10.3797/scipharm.1409-15. Print 2015 Apr-Jun.

22.

Perturbation-expression analysis identifies RUNX1 as a regulator of human mammary stem cell differentiation.

Sokol ES, Sanduja S, Jin DX, Miller DH, Mathis RA, Gupta PB.

PLoS Comput Biol. 2015 Apr 20;11(4):e1004161. doi: 10.1371/journal.pcbi.1004161. eCollection 2015 Apr.

23.

Musashi proteins are post-transcriptional regulators of the epithelial-luminal cell state.

Katz Y, Li F, Lambert NJ, Sokol ES, Tam WL, Cheng AW, Airoldi EM, Lengner CJ, Gupta PB, Yu Z, Jaenisch R, Burge CB.

Elife. 2014 Nov 7;3:e03915. doi: 10.7554/eLife.03915.

24.

De-differentiation confers multidrug resistance via noncanonical PERK-Nrf2 signaling.

Del Vecchio CA, Feng Y, Sokol ES, Tillman EJ, Sanduja S, Reinhardt F, Gupta PB.

PLoS Biol. 2014 Sep 9;12(9):e1001945. doi: 10.1371/journal.pbio.1001945. eCollection 2014 Sep.

25.

Cell-state transitions regulated by SLUG are critical for tissue regeneration and tumor initiation.

Phillips S, Prat A, Sedic M, Proia T, Wronski A, Mazumdar S, Skibinski A, Shirley SH, Perou CM, Gill G, Gupta PB, Kuperwasser C.

Stem Cell Reports. 2014 Apr 24;2(5):633-47. doi: 10.1016/j.stemcr.2014.03.008. eCollection 2014 May 6.

26.

Identification of a Selective Small-Molecule Inhibitor of Breast Cancer Stem Cells—Probe 2.

Carmody LC, Germain A, Morgan B, VerPlank L, Fernandez C, Feng Y, Perez JR, Dandapani S, Munoz B, Palmer M, Lander ES, Gupta PB, Schreiber SL.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2011 Nov 30 [updated 2014 May 13].

27.

Epithelial-to-mesenchymal transition activates PERK-eIF2α and sensitizes cells to endoplasmic reticulum stress.

Feng YX, Sokol ES, Del Vecchio CA, Sanduja S, Claessen JH, Proia TA, Jin DX, Reinhardt F, Ploegh HL, Wang Q, Gupta PB.

Cancer Discov. 2014 Jun;4(6):702-15. doi: 10.1158/2159-8290.CD-13-0945. Epub 2014 Apr 4.

28.

The endoplasmic reticulum may be an Achilles' heel of cancer cells that have undergone an epithelial-to-mesenchymal transition.

Feng YX, Sokol ES, Gupta PB.

Mol Cell Oncol. 2014 Oct 29;1(2):e961822. doi: 10.4161/23723548.2014.961822. eCollection 2014 Apr-Jun.

29.

The Hippo transducer TAZ interacts with the SWI/SNF complex to regulate breast epithelial lineage commitment.

Skibinski A, Breindel JL, Prat A, Galván P, Smith E, Rolfs A, Gupta PB, LaBaer J, Kuperwasser C.

Cell Rep. 2014 Mar 27;6(6):1059-1072. doi: 10.1016/j.celrep.2014.02.038. Epub 2014 Mar 6.

30.

Identification, isolation and characterization of process related impurities in ezetimibe.

Guntupalli S, Ray UK, Murali N, Gupta PB, Kumar VJ, Satheesh D, Islam A.

J Pharm Biomed Anal. 2014 Jan;88:385-90. doi: 10.1016/j.jpba.2013.09.020. Epub 2013 Oct 5.

PMID:
24176742
31.

Identification of a Selective Small-Molecule Inhibitor of Breast Cancer Stem Cells - Probe 3.

Carmody L, Germain A, Morgan B, VerPlank L, Fernandez C, Feng Y, Perez J, Dandapani S, Munoz B, Palmer M, Lander ES, Gupta PB, Schreiber SL.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2011 Sep 28 [updated 2013 Mar 7].

32.

Identification of a Selective Small-Molecule Inhibitor of Breast Cancer Stem Cells - Probe 1.

Carmody L, Germain A, Morgan B, VerPlank L, Fernandez C, Forbeck E, Ting A, Feng Y, Perez J, Dandapani S, Munoz B, Palmer M, Lander E, Gupta PB, Schreiber SL.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2011 Apr 15 [updated 2013 Feb 28].

33.

Comparative evaluation of efficacy and safety of artesunate-lumefantrine vs. artemether-lumefantrine fixed-dose combination in the treatment of uncomplicated Plasmodium falciparum malaria.

Pareek A, Chandurkar N, Srivastav V, Lakhani J, Karmakar PS, Basu S, Ray A, Pednekar S, Gupta PB, Suthar N, Lakhani S.

Trop Med Int Health. 2013 May;18(5):578-87. doi: 10.1111/tmi.12088. Epub 2013 Mar 14.

34.

Cinnamides as selective small-molecule inhibitors of a cellular model of breast cancer stem cells.

Germain AR, Carmody LC, Nag PP, Morgan B, Verplank L, Fernandez C, Donckele E, Feng Y, Perez JR, Dandapani S, Palmer M, Lander ES, Gupta PB, Schreiber SL, Munoz B.

Bioorg Med Chem Lett. 2013 Mar 15;23(6):1834-8. doi: 10.1016/j.bmcl.2013.01.025. Epub 2013 Jan 16.

PMID:
23403082
35.

Comparison of haemodynamic responses to intubation: Flexible fibreoptic bronchoscope versus bonfils rigid intubation endoscope.

Gupta K, Girdhar KK, Anand R, Majgi SM, Gupta SP, Gupta PB.

Indian J Anaesth. 2012 Jul;56(4):353-8. doi: 10.4103/0019-5049.100816.

36.

Protein array patterning by diffusive gel stamping.

Anwar M, Gupta PB, Palaniapan R, Matsudaira P.

PLoS One. 2012;7(10):e46382. doi: 10.1371/journal.pone.0046382. Epub 2012 Oct 10.

37.

Identification of a selective small molecule inhibitor of breast cancer stem cells.

Germain AR, Carmody LC, Morgan B, Fernandez C, Forbeck E, Lewis TA, Nag PP, Ting A, VerPlank L, Feng Y, Perez JR, Dandapani S, Palmer M, Lander ES, Gupta PB, Schreiber SL, Munoz B.

Bioorg Med Chem Lett. 2012 May 15;22(10):3571-4. doi: 10.1016/j.bmcl.2012.01.035. Epub 2012 Jan 25.

PMID:
22503247
38.

Chromatin-modifying enzymes as modulators of reprogramming.

Onder TT, Kara N, Cherry A, Sinha AU, Zhu N, Bernt KM, Cahan P, Marcarci BO, Unternaehrer J, Gupta PB, Lander ES, Armstrong SA, Daley GQ.

Nature. 2012 Mar 4;483(7391):598-602. doi: 10.1038/nature10953.

39.

Functional heterogeneity of breast fibroblasts is defined by a prostaglandin secretory phenotype that promotes expansion of cancer-stem like cells.

Rudnick JA, Arendt LM, Klebba I, Hinds JW, Iyer V, Gupta PB, Naber SP, Kuperwasser C.

PLoS One. 2011;6(9):e24605. doi: 10.1371/journal.pone.0024605. Epub 2011 Sep 21.

40.

Stochastic state transitions give rise to phenotypic equilibrium in populations of cancer cells.

Gupta PB, Fillmore CM, Jiang G, Shapira SD, Tao K, Kuperwasser C, Lander ES.

Cell. 2011 Aug 19;146(4):633-44. doi: 10.1016/j.cell.2011.07.026. Erratum in: Cell. 2011 Nov 23;147(5):1197. Cell. 2011 Sep 16;146(6):1042.

41.

Genetic predisposition directs breast cancer phenotype by dictating progenitor cell fate.

Proia TA, Keller PJ, Gupta PB, Klebba I, Jones AD, Sedic M, Gilmore H, Tung N, Naber SP, Schnitt S, Lander ES, Kuperwasser C.

Cell Stem Cell. 2011 Feb 4;8(2):149-63. doi: 10.1016/j.stem.2010.12.007.

42.

Estrogen expands breast cancer stem-like cells through paracrine FGF/Tbx3 signaling.

Fillmore CM, Gupta PB, Rudnick JA, Caballero S, Keller PJ, Lander ES, Kuperwasser C.

Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21737-42. doi: 10.1073/pnas.1007863107. Epub 2010 Nov 22.

43.

Identification, isolation and characterization of a new degradation product in sultamicillin drug substance.

Kumar VJ, Gupta PB, Kumar KS, Ray UK, Sreenivasulu B, Kumar GS, Rao KR, Sharma HK, Mukkanti K.

J Pharm Biomed Anal. 2011 Feb 20;54(3):582-7. doi: 10.1016/j.jpba.2010.09.016. Epub 2010 Sep 19.

PMID:
20934824
44.

Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes.

Taube JH, Herschkowitz JI, Komurov K, Zhou AY, Gupta S, Yang J, Hartwell K, Onder TT, Gupta PB, Evans KW, Hollier BG, Ram PT, Lander ES, Rosen JM, Weinberg RA, Mani SA.

Proc Natl Acad Sci U S A. 2010 Aug 31;107(35):15449-54. doi: 10.1073/pnas.1004900107. Epub 2010 Aug 16. Erratum in: Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):19132.

45.

Identification, isolation and characterization of new impurity in rabeprazole sodium.

Rao PS, Ray UK, Gupta PB, Rao DV, Islam A, Rajput P, Mukkanti K.

J Pharm Biomed Anal. 2010 Aug 1;52(4):620-4. doi: 10.1016/j.jpba.2010.01.034. Epub 2010 Jan 25.

PMID:
20153594
46.

A physical and regulatory map of host-influenza interactions reveals pathways in H1N1 infection.

Shapira SD, Gat-Viks I, Shum BO, Dricot A, de Grace MM, Wu L, Gupta PB, Hao T, Silver SJ, Root DE, Hill DE, Regev A, Hacohen N.

Cell. 2009 Dec 24;139(7):1255-67. doi: 10.1016/j.cell.2009.12.018.

47.

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1.

Barbie DA, Tamayo P, Boehm JS, Kim SY, Moody SE, Dunn IF, Schinzel AC, Sandy P, Meylan E, Scholl C, Fröhling S, Chan EM, Sos ML, Michel K, Mermel C, Silver SJ, Weir BA, Reiling JH, Sheng Q, Gupta PB, Wadlow RC, Le H, Hoersch S, Wittner BS, Ramaswamy S, Livingston DM, Sabatini DM, Meyerson M, Thomas RK, Lander ES, Mesirov JP, Root DE, Gilliland DG, Jacks T, Hahn WC.

Nature. 2009 Nov 5;462(7269):108-12. doi: 10.1038/nature08460. Epub 2009 Oct 21.

48.

Cancer stem cells: mirage or reality?

Gupta PB, Chaffer CL, Weinberg RA.

Nat Med. 2009 Sep;15(9):1010-2. doi: 10.1038/nm0909-1010. Epub 2009 Sep 4. Review.

PMID:
19734877
49.

Identification of selective inhibitors of cancer stem cells by high-throughput screening.

Gupta PB, Onder TT, Jiang G, Tao K, Kuperwasser C, Weinberg RA, Lander ES.

Cell. 2009 Aug 21;138(4):645-659. doi: 10.1016/j.cell.2009.06.034. Epub 2009 Aug 13.

50.

AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer.

Vasudevan KM, Barbie DA, Davies MA, Rabinovsky R, McNear CJ, Kim JJ, Hennessy BT, Tseng H, Pochanard P, Kim SY, Dunn IF, Schinzel AC, Sandy P, Hoersch S, Sheng Q, Gupta PB, Boehm JS, Reiling JH, Silver S, Lu Y, Stemke-Hale K, Dutta B, Joy C, Sahin AA, Gonzalez-Angulo AM, Lluch A, Rameh LE, Jacks T, Root DE, Lander ES, Mills GB, Hahn WC, Sellers WR, Garraway LA.

Cancer Cell. 2009 Jul 7;16(1):21-32. doi: 10.1016/j.ccr.2009.04.012.

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