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Items: 1 to 50 of 139

1.

Preclinical development of gastro-protective botanical candidate from Woodfordia fruticosa: Chemical standardization, efficacy, pharmacokinetics and safety pharmacology.

Khan IA, Singh A, Mindala DP, Meena S, Vij B, Yadav AK, Roy S, Nandi U, Katare AK, Jaglan S, Singh D, Gupta AP, Gupta P, Singh S, Tikko MK, Singh G, Vishwakarma RA.

J Ethnopharmacol. 2019 Jun 10:112023. doi: 10.1016/j.jep.2019.112023. [Epub ahead of print]

PMID:
31195031
2.

Indolylkojyl methane analogue IKM5 potentially inhibits invasion of breast cancer cells via attenuation of GRP78.

Nayak D, Katoch A, Sharma D, Faheem MM, Chakraborty S, Sahu PK, Chikan NA, Amin H, Gupta AP, Gandhi SG, Mukherjee D, Goswami A.

Breast Cancer Res Treat. 2019 Jun 7. doi: 10.1007/s10549-019-05301-0. [Epub ahead of print]

PMID:
31175498
3.

Pancreastatin inhibitor activates AMPK pathway via GRP78 and ameliorates dexamethasone induced fatty liver disease in C57BL/6 mice.

Gupta AP, Singh P, Garg R, Valicherla GR, Riyazuddin M, Syed AA, Hossain Z, Gayen JR.

Biomed Pharmacother. 2019 Aug;116:108959. doi: 10.1016/j.biopha.2019.108959. Epub 2019 May 17.

4.

Cutaneous Melanoma, Version 2.2019, NCCN Clinical Practice Guidelines in Oncology.

Coit DG, Thompson JA, Albertini MR, Barker C, Carson WE, Contreras C, Daniels GA, DiMaio D, Fields RC, Fleming MD, Freeman M, Galan A, Gastman B, Guild V, Johnson D, Joseph RW, Lange JR, Nath S, Olszanski AJ, Ott P, Gupta AP, Ross MI, Salama AK, Skitzki J, Sosman J, Swetter SM, Tanabe KK, Wuthrick E, McMillian NR, Engh AM.

J Natl Compr Canc Netw. 2019 Apr 1;17(4):367-402. doi: 10.6004/jnccn.2019.0018.

PMID:
30959471
5.

Role of brown adipose tissue in modulating adipose tissue inflammation and insulin resistance in high-fat diet fed mice.

Shankar K, Kumar D, Gupta S, Varshney S, Rajan S, Srivastava A, Gupta A, Gupta AP, Vishwakarma AL, Gayen JR, Gaikwad AN.

Eur J Pharmacol. 2019 Jul 5;854:354-364. doi: 10.1016/j.ejphar.2019.02.044. Epub 2019 Feb 27.

PMID:
30822393
6.

Enhanced potential of biomimetic, silver nanoparticles functionalized Antheraea mylitta (tasar) silk fibroin nanofibrous mats for skin tissue engineering.

Srivastava CM, Purwar R, Gupta AP.

Int J Biol Macromol. 2019 Jun 1;130:437-453. doi: 10.1016/j.ijbiomac.2018.12.255. Epub 2019 Feb 8.

PMID:
30738903
7.

Use of Dynamic MRI of the Pelvic Floor in the Assessment of Anterior Compartment Disorders.

Gupta AP, Pandya PR, Nguyen ML, Fashokun T, Macura KJ.

Curr Urol Rep. 2018 Nov 13;19(12):112. doi: 10.1007/s11934-018-0862-4. Review.

PMID:
30421087
8.

Rosiglitazone up-regulates glial fibrillary acidic protein via HB-EGF secreted from astrocytes and neurons through PPARγ pathway and reduces apoptosis in high-fat diet-fed mice.

Kushwaha R, Mishra J, Gupta AP, Gupta K, Vishwakarma J, Chattopadhyay N, Gayen JR, Kamthan M, Bandyopadhyay S.

J Neurochem. 2019 Jun;149(5):679-698. doi: 10.1111/jnc.14610. Epub 2018 Dec 7.

PMID:
30311190
9.

Determination of permeability, plasma protein binding, blood partitioning, pharmacokinetics and tissue distribution of Withanolide A in rats: A neuroprotective steroidal lactone.

Singh SK, Valicherla GR, Joshi P, Shahi S, Syed AA, Gupta AP, Hossain Z, Italiya K, Makadia V, Singh SK, Wahajuddin M, Gayen JR.

Drug Dev Res. 2018 Nov;79(7):339-351. doi: 10.1002/ddr.21463. Epub 2018 Oct 4.

PMID:
30284738
10.

Elucidation of pharmacokinetics of novel DNA ligase I inhibitor, S012-1332 in rats: Integration of in vitro and in vivo findings.

Riyazuddin M, Valicherla GR, Husain A, Hussain MK, Shukla M, Katekar R, Gupta AP, Singh P, Banerjee D, Hajela K, Gayen JR.

J Pharm Biomed Anal. 2019 Jan 5;162:205-214. doi: 10.1016/j.jpba.2018.09.031. Epub 2018 Sep 18.

PMID:
30265980
11.

Discovery of pancreastatin inhibitor PSTi8 for the treatment of insulin resistance and diabetes: studies in rodent models of diabetes mellitus.

Hossain Z, Valicherla GR, Gupta AP, Syed AA, Riyazuddin M, Chandra S, Siddiqi MI, Gayen JR.

Sci Rep. 2018 Jun 7;8(1):8715. doi: 10.1038/s41598-018-27018-8.

12.

Carbon Nanotube Field Emitters Synthesized on Metal Alloy Substrate by PECVD for Customized Compact Field Emission Devices to Be Used in X-Ray Source Applications.

Park S, Gupta AP, Yeo SJ, Jung J, Paik SH, Mativenga M, Kim SH, Shin JH, Ahn JS, Ryu J.

Nanomaterials (Basel). 2018 May 29;8(6). pii: E378. doi: 10.3390/nano8060378.

13.

Glucose and lipid metabolism alterations in liver and adipose tissue pre-dispose p47phox knockout mice to systemic insulin resistance.

Kanuri BN, Rebello SC, Pathak P, Agarwal H, Kanshana JS, Awasthi D, Gupta AP, Gayen JR, Jagavelu K, Dikshit M.

Free Radic Res. 2018 May;52(5):568-582. doi: 10.1080/10715762.2018.1453136. Epub 2018 Apr 3.

PMID:
29544378
14.

Corrigendum: Mannitol Stress Directs Flavonoid Metabolism toward Synthesis of Flavones via Differential Regulation of Two Cytochrome P450 Monooxygenases in Coleus forskohlii.

Awasthi P, Gupta AP, Bedi YS, Vishwakarma RA, Gandhi SG.

Front Plant Sci. 2018 Jan 8;8:2222. doi: 10.3389/fpls.2017.02222. eCollection 2017.

15.

Modulation of dietary folate with age confers selective hepatocellular epigenetic imprints through DNA methylation.

Najar RA, Wani NA, Bhat JA, Dar NJ, Rahat B, Gupta AP, Kaur J, Kaur J, Hamid A.

J Nutr Biochem. 2018 Mar;53:121-132. doi: 10.1016/j.jnutbio.2017.10.007. Epub 2017 Nov 2.

PMID:
29220669
16.

Determination of ZSTK474, a novel Pan PI3K inhibitor in mouse plasma by LC-MS/MS and its application to Pharmacokinetics.

Singh A, Thatikonda T, Kumar A, Wazir P, V V, Nandi U, Singh PP, Singh S, Gupta AP, Tikoo MK, Singh G, Vishwakarma R.

J Pharm Biomed Anal. 2018 Feb 5;149:387-393. doi: 10.1016/j.jpba.2017.11.031. Epub 2017 Nov 11.

PMID:
29175554
17.

Mining and characterization of EST-SSR markers for Zingiber officinale Roscoe with transferability to other species of Zingiberaceae.

Awasthi P, Singh A, Sheikh G, Mahajan V, Gupta AP, Gupta S, Bedi YS, Gandhi SG.

Physiol Mol Biol Plants. 2017 Oct;23(4):925-931. doi: 10.1007/s12298-017-0472-5. Epub 2017 Oct 11.

18.

Histone 4 lysine 8 acetylation regulates proliferation and host-pathogen interaction in Plasmodium falciparum.

Gupta AP, Zhu L, Tripathi J, Kucharski M, Patra A, Bozdech Z.

Epigenetics Chromatin. 2017 Aug 22;10(1):40. doi: 10.1186/s13072-017-0147-z.

19.

Direct Synthesis of Carbon Nanotube Field Emitters on Metal Substrate for Open-Type X-ray Source in Medical Imaging.

Gupta AP, Park S, Yeo SJ, Jung J, Cho C, Paik SH, Park H, Cho YC, Kim SH, Shin JH, Ahn JS, Ryu J.

Materials (Basel). 2017 Jul 29;10(8). pii: E878. doi: 10.3390/ma10080878.

20.

Isoalantolactone derivative promotes glucose utilization in skeletal muscle cells and increases energy expenditure in db/db mice via activating AMPK-dependent signaling.

Arha D, Ramakrishna E, Gupta AP, Rai AK, Sharma A, Ahmad I, Riyazuddin M, Gayen JR, Maurya R, Tamrakar AK.

Mol Cell Endocrinol. 2018 Jan 15;460:134-151. doi: 10.1016/j.mce.2017.07.015. Epub 2017 Jul 20.

PMID:
28736255
21.

Molecular and functional characterization of two isoforms of chalcone synthase and their expression analysis in relation to flavonoid constituents in Grewia asiatica L.

Wani TA, Pandith SA, Gupta AP, Chandra S, Sharma N, Lattoo SK.

PLoS One. 2017 Jun 29;12(6):e0179155. doi: 10.1371/journal.pone.0179155. eCollection 2017.

22.

Development and validation of a highly sensitive LC-ESI-MS/MS method for estimation of IIIM-MCD-211, a novel nitrofuranyl methyl piperazine derivative with potential activity against tuberculosis: Application to drug development.

Magotra A, Sharma A, Gupta AP, Wazir P, Sharma S, Singh PP, Tikoo MK, Vishwakarma RA, Singh G, Nandi U.

J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Aug 15;1060:200-206. doi: 10.1016/j.jchromb.2017.06.015. Epub 2017 Jun 8.

PMID:
28623772
23.

Epigenetic landscapes underlining global patterns of gene expression in the human malaria parasite, Plasmodium falciparum.

Gupta AP, Bozdech Z.

Int J Parasitol. 2017 Jun;47(7):399-407. doi: 10.1016/j.ijpara.2016.10.008. Epub 2017 Apr 13. Review.

PMID:
28414071
24.

Corrigendum: Altered glucose and lipid homeostasis in liver and adipose tissue pre-dispose inducible NOS knockout mice to insulin resistance.

Kanuri BN, Kanshana JS, Rebello SC, Pathak P, Gupta AP, Gayen JR, Jagavelu K, Dikshit M.

Sci Rep. 2017 Apr 6;7:46010. doi: 10.1038/srep46010. No abstract available.

25.

Epigenetic modifier induced enhancement of fumiquinazoline C production in Aspergillus fumigatus (GA-L7): an endophytic fungus from Grewia asiatica L.

Magotra A, Kumar M, Kushwaha M, Awasthi P, Raina C, Gupta AP, Shah BA, Gandhi SG, Chaubey A.

AMB Express. 2017 Dec;7(1):43. doi: 10.1186/s13568-017-0343-z. Epub 2017 Feb 17.

26.

Altered glucose and lipid homeostasis in liver and adipose tissue pre-dispose inducible NOS knockout mice to insulin resistance.

Kanuri BN, Kanshana JS, Rebello SC, Pathak P, Gupta AP, Gayen JR, Jagavelu K, Dikshit M.

Sci Rep. 2017 Jan 20;7:41009. doi: 10.1038/srep41009. Erratum in: Sci Rep. 2017 Apr 06;7:46010.

27.

Cardioprotective Effect of Ulmus wallichiana Planchon in β-Adrenergic Agonist Induced Cardiac Hypertrophy.

Syed AA, Lahiri S, Mohan D, Valicherla GR, Gupta AP, Kumar S, Maurya R, Bora HK, Hanif K, Gayen JR.

Front Pharmacol. 2016 Dec 21;7:510. doi: 10.3389/fphar.2016.00510. eCollection 2016.

28.

Synthesis of substituted 2H-benzo[e]indazole-9-carboxylate as a potent antihyperglycemic agent that may act through IRS-1, Akt and GSK-3β pathways.

Taneja G, Gupta CP, Mishra S, Srivastava R, Rahuja N, Rawat AK, Pandey J, Gupta AP, Jaiswal N, Gayen JR, Tamrakar AK, Srivastava AK, Goel A.

Medchemcomm. 2016 Nov 15;8(2):329-337. doi: 10.1039/c6md00467a. eCollection 2017 Feb 1.

29.

Isolation and characterization of bioactive metabolites from Xylaria psidii, an endophytic fungus of the medicinal plant Aegle marmelos and their role in mitochondrial dependent apoptosis against pancreatic cancer cells.

Arora D, Sharma N, Singamaneni V, Sharma V, Kushwaha M, Abrol V, Guru S, Sharma S, Gupta AP, Bhushan S, Jaglan S, Gupta P.

Phytomedicine. 2016 Nov 15;23(12):1312-1320. doi: 10.1016/j.phymed.2016.07.004. Epub 2016 Jul 18.

PMID:
27765350
30.

Evaluation of anti-hypertensive activity of Ulmus wallichiana extract and fraction in SHR, DOCA-salt- and L-NAME-induced hypertensive rats.

Syed AA, Lahiri S, Mohan D, Valicherla GR, Gupta AP, Riyazuddin M, Kumar S, Maurya R, Hanif K, Gayen JR.

J Ethnopharmacol. 2016 Dec 4;193:555-565. doi: 10.1016/j.jep.2016.10.008. Epub 2016 Oct 5.

PMID:
27720848
31.

Leaf spot disease adversely affects human health-promoting constituents and withanolide biosynthesis in Withania somnifera (L.) Dunal.

Singh V, Singh B, Sharma A, Kaur K, Gupta AP, Salar RK, Hallan V, Pati PK.

J Appl Microbiol. 2017 Jan;122(1):153-165. doi: 10.1111/jam.13314. Epub 2016 Nov 15.

PMID:
27709727
32.

NCCN Guidelines Insights: Melanoma, Version 3.2016.

Coit DG, Thompson JA, Algazi A, Andtbacka R, Bichakjian CK, Carson WE 3rd, Daniels GA, DiMaio D, Fields RC, Fleming MD, Gastman B, Gonzalez R, Guild V, Johnson D, Joseph RW, Lange JR, Martini MC, Materin MA, Olszanski AJ, Ott P, Gupta AP, Ross MI, Salama AK, Skitzki J, Swetter SM, Tanabe KK, Torres-Roca JF, Trisal V, Urist MM, McMillian N, Engh A.

J Natl Compr Canc Netw. 2016 Aug;14(8):945-58.

PMID:
27496110
33.

Mannitol Stress Directs Flavonoid Metabolism toward Synthesis of Flavones via Differential Regulation of Two Cytochrome P450 Monooxygenases in Coleus forskohlii.

Awasthi P, Gupta AP, Bedi YS, Vishwakarma RA, Gandhi SG.

Front Plant Sci. 2016 Jul 6;7:985. doi: 10.3389/fpls.2016.00985. eCollection 2016. Erratum in: Front Plant Sci. 2018 Jan 08;8:2222.

34.

I2/Aqueous TBHP-Catalyzed Coupling of Amides with Methylarenes/Aldehydes/Alcohols: Metal-Free Synthesis of Imides.

Aruri H, Singh U, Kumar S, Kushwaha M, Gupta AP, Vishwakarma RA, Singh PP.

Org Lett. 2016 Aug 5;18(15):3638-41. doi: 10.1021/acs.orglett.6b01684. Epub 2016 Jul 19.

PMID:
27434140
35.

Functional Promiscuity of Two Divergent Paralogs of Type III Plant Polyketide Synthases.

Pandith SA, Dhar N, Rana S, Bhat WW, Kushwaha M, Gupta AP, Shah MA, Vishwakarma R, Lattoo SK.

Plant Physiol. 2016 Aug;171(4):2599-619. doi: 10.1104/pp.16.00003. Epub 2016 Jun 7.

36.

Formulation optimization of Docetaxel loaded self-emulsifying drug delivery system to enhance bioavailability and anti-tumor activity.

Valicherla GR, Dave KM, Syed AA, Riyazuddin M, Gupta AP, Singh A, Wahajuddin, Mitra K, Datta D, Gayen JR.

Sci Rep. 2016 May 31;6:26895. doi: 10.1038/srep26895.

37.

DNA damage regulation and its role in drug-related phenotypes in the malaria parasites.

Gupta DK, Patra AT, Zhu L, Gupta AP, Bozdech Z.

Sci Rep. 2016 Apr 1;6:23603. doi: 10.1038/srep23603.

38.

Development and validation of a highly sensitive LC-MS/MS-ESI method for quantification of IIIM-019-A novel nitroimidazole derivative with promising action against Tuberculosis: Application to drug development.

Kour G, Chandan BK, Khullar M, Munagala G, Singh PP, Bhagat A, Gupta AP, Vishwakarma RA, Ahmed Z.

J Pharm Biomed Anal. 2016 May 30;124:26-33. doi: 10.1016/j.jpba.2016.02.027. Epub 2016 Feb 22.

PMID:
26922579
39.

Plant Omics: Isolation, Identification, and Expression Analysis of Cytochrome P450 Gene Sequences from Coleus forskohlii.

Awasthi P, Mahajan V, Rather IA, Gupta AP, Rasool S, Bedi YS, Vishwakarma RA, Gandhi SG.

OMICS. 2015 Dec;19(12):782-92. doi: 10.1089/omi.2015.0148.

PMID:
26669713
40.

2-Oxo-Driven N2 Elimination Induced Decarbonylative Cyclization Reaction in Benzotriazoles to 6-Aminophenanthridines.

Battula S, Kumar A, Gupta AP, Ahmed QN.

Org Lett. 2015 Nov 20;17(22):5562-5. doi: 10.1021/acs.orglett.5b02699. Epub 2015 Nov 2.

PMID:
26523429
41.

Amino Catalytic Oxidative Thioesterification Approach to α-Ketothioesters.

Mupparapu N, Khushwaha M, Gupta AP, Singh PP, Ahmed QN.

J Org Chem. 2015 Nov 20;80(22):11588-92. doi: 10.1021/acs.joc.5b02176. Epub 2015 Oct 28.

PMID:
26485643
42.

Simultaneous Quantification of Five Bioactive Flavonoids in High Altitude Plant Actinocarya tibetica by LC-ESI-MS/MS.

Singh B, Jain SK, Bharate SB, Kushwaha M, Gupta AP, Vishwakarma RA.

J AOAC Int. 2015 Jul-Aug;98(4):907-12. doi: 10.5740/jaoacint.14-270.

PMID:
26268971
43.

A Plasmodium Falciparum Bromodomain Protein Regulates Invasion Gene Expression.

Josling GA, Petter M, Oehring SC, Gupta AP, Dietz O, Wilson DW, Schubert T, Längst G, Gilson PR, Crabb BS, Moes S, Jenoe P, Lim SW, Brown GV, Bozdech Z, Voss TS, Duffy MF.

Cell Host Microbe. 2015 Jun 10;17(6):741-51. doi: 10.1016/j.chom.2015.05.009.

44.
45.

A therapeutically relevant, 3,3'-diindolylmethane derivative NGD16 attenuates angiogenesis by targeting glucose regulated protein, 78kDa (GRP78).

Nayak D, Amin H, Rah B, Ur Rasool R, Sharma D, Gupta AP, Kushwaha M, Mukherjee D, Goswami A.

Chem Biol Interact. 2015 May 5;232:58-67. doi: 10.1016/j.cbi.2015.03.008. Epub 2015 Mar 17.

PMID:
25794856
46.

NMR studies of the chiral selectivity of self-assembled guanosinemonophosphate.

Gupta AP, Taylor WJ, McGown LB, Kempf JG.

J Phys Chem B. 2014 Dec 11;118(49):14243-56. doi: 10.1021/jp5075016. Epub 2014 Nov 26.

PMID:
25401946
47.

Genome-wide analysis in Plasmodium falciparum reveals early and late phases of RNA polymerase II occupancy during the infectious cycle.

Rai R, Zhu L, Chen H, Gupta AP, Sze SK, Zheng J, Ruedl C, Bozdech Z, Featherstone M.

BMC Genomics. 2014 Nov 6;15:959. doi: 10.1186/1471-2164-15-959.

48.

Multi-elemental profiling and chemo-metric validation revealed nutritional qualities of Zingiber officinale.

Pandotra P, Viz B, Ram G, Gupta AP, Gupta S.

Ecotoxicol Environ Saf. 2015 Apr;114:222-31. doi: 10.1016/j.ecoenv.2014.01.021. Epub 2014 Jun 19.

PMID:
24953004
49.

Dysoxylum binectariferum bark as a new source of anticancer drug camptothecin: bioactivity-guided isolation and LCMS-based quantification.

Jain SK, Meena S, Gupta AP, Kushwaha M, Uma Shaanker R, Jaglan S, Bharate SB, Vishwakarma RA.

Bioorg Med Chem Lett. 2014 Jul 15;24(14):3146-9. doi: 10.1016/j.bmcl.2014.05.001. Epub 2014 May 10.

PMID:
24878199
50.

Hepatoprotective activity of LC-ESI-MS standardized Iris spuria rhizome extract on its main bioactive constituents.

Akther N, Andrabi K, Nissar A, Ganaie S, Chandan BK, Gupta AP, Khuswant M, Sultana S, Shawl AS.

Phytomedicine. 2014 Sep 15;21(10):1202-7. doi: 10.1016/j.phymed.2014.04.007. Epub 2014 May 28.

PMID:
24877715

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