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Items: 27

1.

Survivors of Ebola virus disease develop polyfunctional antibody responses.

Gunn BM, Roy V, Karim MM, Hartnett JN, Suscovich TJ, Goba A, Momoh M, Sandi JD, Kanneh L, Andersen KG, Shaffer JG, Schieffelin JS, Garry RF, Grant DS, Alter G.

J Infect Dis. 2019 Jul 12. pii: jiz364. doi: 10.1093/infdis/jiz364. [Epub ahead of print]

PMID:
31301137
2.

Optimal therapeutic activity of monoclonal antibodies against chikungunya virus requires Fc-FcγR interaction on monocytes.

Fox JM, Roy V, Gunn BM, Huang L, Edeling MA, Mack M, Fremont DH, Doranz BJ, Johnson S, Alter G, Diamond MS.

Sci Immunol. 2019 Feb 22;4(32). pii: eaav5062. doi: 10.1126/sciimmunol.aav5062.

3.

A Two-Antibody Pan-Ebolavirus Cocktail Confers Broad Therapeutic Protection in Ferrets and Nonhuman Primates.

Bornholdt ZA, Herbert AS, Mire CE, He S, Cross RW, Wec AZ, Abelson DM, Geisbert JB, James RM, Rahim MN, Zhu W, Borisevich V, Banadyga L, Gunn BM, Agans KN, Wirchnianski AS, Goodwin E, Tierney K, Shestowsky WS, Bohorov O, Bohorova N, Velasco J, Ailor E, Kim D, Pauly MH, Whaley KJ, Alter G, Walker LM, Chandran K, Zeitlin L, Qiu X, Geisbert TW, Dye JM.

Cell Host Microbe. 2019 Jan 9;25(1):49-58.e5. doi: 10.1016/j.chom.2018.12.005.

PMID:
30629918
4.

Development of a Human Antibody Cocktail that Deploys Multiple Functions to Confer Pan-Ebolavirus Protection.

Wec AZ, Bornholdt ZA, He S, Herbert AS, Goodwin E, Wirchnianski AS, Gunn BM, Zhang Z, Zhu W, Liu G, Abelson DM, Moyer CL, Jangra RK, James RM, Bakken RR, Bohorova N, Bohorov O, Kim DH, Pauly MH, Velasco J, Bortz RH 3rd, Whaley KJ, Goldstein T, Anthony SJ, Alter G, Walker LM, Dye JM, Zeitlin L, Qiu X, Chandran K.

Cell Host Microbe. 2019 Jan 9;25(1):39-48.e5. doi: 10.1016/j.chom.2018.12.004.

PMID:
30629917
5.

Antibody-Mediated Protective Mechanisms Induced by a Trivalent Parainfluenza Virus-Vectored Ebolavirus Vaccine.

Kimble JB, Malherbe DC, Meyer M, Gunn BM, Karim MM, Ilinykh PA, Iampietro M, Mohamed KS, Negi S, Gilchuk P, Huang K, Wolf YI, Braun W, Crowe JE, Alter G, Bukreyev A.

J Virol. 2019 Feb 5;93(4). pii: e01845-18. doi: 10.1128/JVI.01845-18. Print 2019 Feb 15.

6.

Antibody-mediated protection against Ebola virus.

Saphire EO, Schendel SL, Gunn BM, Milligan JC, Alter G.

Nat Immunol. 2018 Nov;19(11):1169-1178. doi: 10.1038/s41590-018-0233-9. Epub 2018 Oct 17. Review.

7.

Asymmetric antiviral effects of ebolavirus antibodies targeting glycoprotein stem and glycan cap.

Ilinykh PA, Santos RI, Gunn BM, Kuzmina NA, Shen X, Huang K, Gilchuk P, Flyak AI, Younan P, Alter G, Crowe JE Jr, Bukreyev A.

PLoS Pathog. 2018 Aug 23;14(8):e1007204. doi: 10.1371/journal.ppat.1007204. eCollection 2018 Aug.

8.

Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection.

Saphire EO, Schendel SL, Fusco ML, Gangavarapu K, Gunn BM, Wec AZ, Halfmann PJ, Brannan JM, Herbert AS, Qiu X, Wagh K, He S, Giorgi EE, Theiler J, Pommert KBJ, Krause TB, Turner HL, Murin CD, Pallesen J, Davidson E, Ahmed R, Aman MJ, Bukreyev A, Burton DR, Crowe JE Jr, Davis CW, Georgiou G, Krammer F, Kyratsous CA, Lai JR, Nykiforuk C, Pauly MH, Rijal P, Takada A, Townsend AR, Volchkov V, Walker LM, Wang CI, Zeitlin L, Doranz BJ, Ward AB, Korber B, Kobinger GP, Andersen KG, Kawaoka Y, Alter G, Chandran K, Dye JM; Viral Hemorrhagic Fever Immunotherapeutic Consortium.

Cell. 2018 Aug 9;174(4):938-952.e13. doi: 10.1016/j.cell.2018.07.033.

9.

A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus.

Gunn BM, Yu WH, Karim MM, Brannan JM, Herbert AS, Wec AZ, Halfmann PJ, Fusco ML, Schendel SL, Gangavarapu K, Krause T, Qiu X, He S, Das J, Suscovich TJ, Lai J, Chandran K, Zeitlin L, Crowe JE Jr, Lauffenburger D, Kawaoka Y, Kobinger GP, Andersen KG, Dye JM, Saphire EO, Alter G.

Cell Host Microbe. 2018 Aug 8;24(2):221-233.e5. doi: 10.1016/j.chom.2018.07.009.

10.

Multifunctional Pan-ebolavirus Antibody Recognizes a Site of Broad Vulnerability on the Ebolavirus Glycoprotein.

Gilchuk P, Kuzmina N, Ilinykh PA, Huang K, Gunn BM, Bryan A, Davidson E, Doranz BJ, Turner HL, Fusco ML, Bramble MS, Hoff NA, Binshtein E, Kose N, Flyak AI, Flinko R, Orlandi C, Carnahan R, Parrish EH, Sevy AM, Bombardi RG, Singh PK, Mukadi P, Muyembe-Tamfum JJ, Ohi MD, Saphire EO, Lewis GK, Alter G, Ward AB, Rimoin AW, Bukreyev A, Crowe JE Jr.

Immunity. 2018 Aug 21;49(2):363-374.e10. doi: 10.1016/j.immuni.2018.06.018. Epub 2018 Jul 17.

11.

Neutralizing Antibody Responses following Long-Term Vaccination with HIV-1 Env gp140 in Guinea Pigs.

Bricault CA, Kovacs JM, Badamchi-Zadeh A, McKee K, Shields JL, Gunn BM, Neubauer GH, Ghantous F, Jennings J, Gillis L, Perry J, Nkolola JP, Alter G, Chen B, Stephenson KE, Doria-Rose N, Mascola JR, Seaman MS, Barouch DH.

J Virol. 2018 Jun 13;92(13). pii: e00369-18. doi: 10.1128/JVI.00369-18. Print 2018 Jul 1.

12.

Ross River virus envelope glycans contribute to disease through activation of the host complement system.

Gunn BM, Jones JE, Shabman RS, Whitmore AC, Sarkar S, Blevins LK, Morrison TE, Heise MT.

Virology. 2018 Feb;515:250-260. doi: 10.1016/j.virol.2017.12.022. Epub 2018 Jan 8.

13.

Modulating Antibody Functionality in Infectious Disease and Vaccination.

Gunn BM, Alter G.

Trends Mol Med. 2016 Nov;22(11):969-982. doi: 10.1016/j.molmed.2016.09.002. Epub 2016 Oct 15. Review.

PMID:
27756530
14.

Attenuating mutations in nsP1 reveal tissue-specific mechanisms for control of Ross River virus infection.

Stoermer Burrack KA, Hawman DW, Jupille HJ, Oko L, Minor M, Shives KD, Gunn BM, Long KM, Morrison TE.

J Virol. 2014 Apr;88(7):3719-32. doi: 10.1128/JVI.02609-13. Epub 2014 Jan 15.

15.

Mannose binding lectin is required for alphavirus-induced arthritis/myositis.

Gunn BM, Morrison TE, Whitmore AC, Blevins LK, Hueston L, Fraser RJ, Herrero LJ, Ramirez R, Smith PN, Mahalingam S, Heise MT.

PLoS Pathog. 2012;8(3):e1002586. doi: 10.1371/journal.ppat.1002586. Epub 2012 Mar 22.

16.

A mouse model of chikungunya virus-induced musculoskeletal inflammatory disease: evidence of arthritis, tenosynovitis, myositis, and persistence.

Morrison TE, Oko L, Montgomery SA, Whitmore AC, Lotstein AR, Gunn BM, Elmore SA, Heise MT.

Am J Pathol. 2011 Jan;178(1):32-40. doi: 10.1016/j.ajpath.2010.11.018. Epub 2010 Dec 23.

17.

Mutations in nsP1 and PE2 are critical determinants of Ross River virus-induced musculoskeletal inflammatory disease in a mouse model.

Jupille HJ, Oko L, Stoermer KA, Heise MT, Mahalingam S, Gunn BM, Morrison TE.

Virology. 2011 Feb 5;410(1):216-27. doi: 10.1016/j.virol.2010.11.012. Epub 2010 Dec 4.

18.

Fine-tuning synthesis of Yersinia pestis LcrV from runaway-like replication balanced-lethal plasmid in a Salmonella enterica serovar typhimurium vaccine induces protection against a lethal Y. pestis challenge in mice.

Torres-Escobar A, Juárez-Rodríguez MD, Gunn BM, Branger CG, Tinge SA, Curtiss R 3rd.

Infect Immun. 2010 Jun;78(6):2529-43. doi: 10.1128/IAI.00005-10. Epub 2010 Mar 22.

19.

Construction of recombinant attenuated Salmonella enterica serovar typhimurium vaccine vector strains for safety in newborn and infant mice.

Gunn BM, Wanda SY, Burshell D, Wang C, Curtiss R 3rd.

Clin Vaccine Immunol. 2010 Mar;17(3):354-62. doi: 10.1128/CVI.00412-09. Epub 2010 Jan 6.

20.

Immunogenicity of a live recombinant Salmonella enterica serovar typhimurium vaccine expressing pspA in neonates and infant mice born from naive and immunized mothers.

Shi H, Wang S, Roland KL, Gunn BM, Curtiss R 3rd.

Clin Vaccine Immunol. 2010 Mar;17(3):363-71. doi: 10.1128/CVI.00413-09. Epub 2010 Jan 6.

21.

The impact of chemokine receptor CX3CR1 deficiency during respiratory infections with Mycobacterium tuberculosis or Francisella tularensis.

Hall JD, Kurtz SL, Rigel NW, Gunn BM, Taft-Benz S, Morrison JP, Fong AM, Patel DD, Braunstein M, Kawula TH.

Clin Exp Immunol. 2009 May;156(2):278-84. doi: 10.1111/j.1365-2249.2009.03882.x. Epub 2009 Feb 10.

22.

Salmonella enterica serovar typhimurium strains with regulated delayed attenuation in vivo.

Curtiss R 3rd, Wanda SY, Gunn BM, Zhang X, Tinge SA, Ananthnarayan V, Mo H, Wang S, Kong W.

Infect Immun. 2009 Mar;77(3):1071-82. doi: 10.1128/IAI.00693-08. Epub 2008 Dec 22.

23.

Infected-host-cell repertoire and cellular response in the lung following inhalation of Francisella tularensis Schu S4, LVS, or U112.

Hall JD, Woolard MD, Gunn BM, Craven RR, Taft-Benz S, Frelinger JA, Kawula TH.

Infect Immun. 2008 Dec;76(12):5843-52. doi: 10.1128/IAI.01176-08. Epub 2008 Oct 13.

24.

Presence of wild-type and attenuated Salmonella enterica strains in brain tissues following inoculation of mice by different routes.

Bollen WS, Gunn BM, Mo H, Lay MK, Curtiss R 3rd.

Infect Immun. 2008 Jul;76(7):3268-72. doi: 10.1128/IAI.00244-08. Epub 2008 May 12.

25.

NMR study of G.A and A.A pairing in (dGCGAATAAGCG)2.

Maskos K, Gunn BM, LeBlanc DA, Morden KM.

Biochemistry. 1993 Apr 13;32(14):3583-95.

PMID:
8385483
26.
27.

Fledgling translocation and philopatry in a seabird.

Serventy DL, Gunn BM, Skira IJ, Bradley JS, Wooller RD.

Oecologia. 1989 Nov;81(3):428-429. doi: 10.1007/BF00377094. No abstract available.

PMID:
28311199

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