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Items: 8


SGL5213, a novel and potent intestinal SGLT1 inhibitor, suppresses intestinal glucose absorption and enhances plasma GLP-1 and GLP-2 secretion in rats.

Io F, Gunji E, Koretsune H, Kato K, Sugisaki-Kitano M, Okumura-Kitajima L, Kimura K, Uchida S, Yamamoto K.

Eur J Pharmacol. 2019 Jun 15;853:136-144. doi: 10.1016/j.ejphar.2019.03.023. Epub 2019 Mar 13.


In vitro characterization of luseogliflozin, a potent and competitive sodium glucose co-transporter 2 inhibitor: Inhibition kinetics and binding studies.

Uchida S, Mitani A, Gunji E, Takahashi T, Yamamoto K.

J Pharmacol Sci. 2015 May;128(1):54-7. doi: 10.1016/j.jphs.2015.04.001. Epub 2015 Apr 9.


A Strategy for assessing potential drug-drug interactions of a concomitant agent against a drug absorbed via an intestinal transporter in humans.

Mizuno-Yasuhira A, Nakai Y, Gunji E, Uchida S, Takahashi T, Kinoshita K, Jingu S, Sakai S, Samukawa Y, Yamaguchi J.

Drug Metab Dispos. 2014 Sep;42(9):1456-65. doi: 10.1124/dmd.114.058305. Epub 2014 Jul 8.


TS-071 is a novel, potent and selective renal sodium-glucose cotransporter 2 (SGLT2) inhibitor with anti-hyperglycaemic activity.

Yamamoto K, Uchida S, Kitano K, Fukuhara N, Okumura-Kitajima L, Gunji E, Kozakai A, Tomoike H, Kojima N, Asami J, Toyoda H, Arai M, Takahashi T, Takahashi K.

Br J Pharmacol. 2011 Sep;164(1):181-91. doi: 10.1111/j.1476-5381.2011.01340.x.


Molecular dissection of the mechanisms of substrate recognition and F-actin-mediated activation of cofilin-phosphatase Slingshot-1.

Kurita S, Watanabe Y, Gunji E, Ohashi K, Mizuno K.

J Biol Chem. 2008 Nov 21;283(47):32542-52. doi: 10.1074/jbc.M804627200. Epub 2008 Sep 22.


Actin filaments-stabilizing and -bundling activities of cofilin-phosphatase Slingshot-1.

Kurita S, Gunji E, Ohashi K, Mizuno K.

Genes Cells. 2007 May;12(5):663-76.


The disposition of thioperamide, a histamine H3-receptor antagonist, in rats.

Sakurai E, Gunji E, Iizuka Y, Hikichi N, Maeyama K, Watanabe T.

J Pharm Pharmacol. 1994 Mar;46(3):209-12.


In vivo microdialysis measurement of histamine in rat blood effects of compound 48/80 and histamine receptor antagonists.

Sakurai E, Gunji E, Iizuka Y, Hikichi N, Maeyama K, Watanabe T.

J Pharmacol Toxicol Methods. 1993 Apr;29(2):105-9.


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