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Items: 1 to 50 of 53

1.

Inosine RNA modifications are enriched at the codon wobble position in mouse oocytes and eggs.

Brachova P, Alvarez NS, Hong X, Gunewardena S, Vincent KA, Latham KE, Christenson LK.

Biol Reprod. 2019 Jul 26. pii: ioz130. doi: 10.1093/biolre/ioz130. [Epub ahead of print]

PMID:
31346607
2.

Analysis of lncRNA-miRNA-mRNA Interactions in Hyper-proliferative Human Pulmonary Arterial Smooth Muscle Cells.

Chinnappan M, Gunewardena S, Chalise P, Dhillon NK.

Sci Rep. 2019 Jul 19;9(1):10533. doi: 10.1038/s41598-019-46981-4.

3.

Pleotropic role of RNA binding protein CELF2 in autophagy induction.

New J, Subramaniam D, Ramalingam S, Enders J, Sayed AAA, Ponnurangam S, Standing D, Ramamoorthy P, O'Neil M, Dixon DA, Saha S, Umar S, Gunewardena S, Jensen RA, Thomas SM, Anant S.

Mol Carcinog. 2019 Aug;58(8):1400-1409. doi: 10.1002/mc.23023. Epub 2019 Apr 24.

PMID:
31020708
4.

Super-enhancers: novel target for pancreatic ductal adenocarcinoma.

Ghosh C, Paul S, Dandawate P, Gunewardena SS, Subramaniam D, West C, Anant S, Dhar A.

Oncotarget. 2019 Feb 22;10(16):1554-1571. doi: 10.18632/oncotarget.26704. eCollection 2019 Feb 22.

5.

CYR61/CCN1 Regulates dCK and CTGF and Causes Gemcitabine-resistant Phenotype in Pancreatic Ductal Adenocarcinoma.

Maity G, Ghosh A, Gupta V, Haque I, Sarkar S, Das A, Dhar K, Bhavanasi S, Gunewardena SS, Von Hoff DD, Mallik S, Kambhampati S, Banerjee SK, Banerjee S.

Mol Cancer Ther. 2019 Apr;18(4):788-800. doi: 10.1158/1535-7163.MCT-18-0899. Epub 2019 Feb 20.

PMID:
30787177
6.

Metastatic Tumor-in-a-Dish, a Novel Multicellular Organoid to Study Lung Colonization and Predict Therapeutic Response.

Ramamoorthy P, Thomas SM, Kaushik G, Subramaniam D, Chastain KM, Dhar A, Tawfik O, Kasi A, Sun W, Ramalingam S, Gunewardena S, Umar S, Mammen JM, Padhye SB, Weir SJ, Jensen RA, Sittampalam GS, Anant S.

Cancer Res. 2019 Apr 1;79(7):1681-1695. doi: 10.1158/0008-5472.CAN-18-2602. Epub 2019 Jan 23.

PMID:
30674533
7.

Hepatocyte Nuclear Factor 4 Alpha Activation Is Essential for Termination of Liver Regeneration in Mice.

Huck I, Gunewardena S, Espanol-Suner R, Willenbring H, Apte U.

Hepatology. 2019 Aug;70(2):666-681. doi: 10.1002/hep.30405. Epub 2019 Mar 10.

PMID:
30520062
8.

Micro-RNAs involved in cellular proliferation have altered expression profiles in granulosa of young women with diminished ovarian reserve.

Woo I, Christenson LK, Gunewardena S, Ingles SA, Thomas S, Ahmady A, Chung K, Bendikson K, Paulson R, McGinnis LK.

J Assist Reprod Genet. 2018 Oct;35(10):1777-1786. doi: 10.1007/s10815-018-1239-9. Epub 2018 Jul 9.

PMID:
29987422
9.

Feasibility of microRNA profiling in human inner ear perilymph.

Shew M, Warnecke A, Lenarz T, Schmitt H, Gunewardena S, Staecker H.

Neuroreport. 2018 Aug 1;29(11):894-901. doi: 10.1097/WNR.0000000000001049.

PMID:
29781875
10.

Macrophage-derived extracellular vesicles mediate smooth muscle hyperplasia: role of altered miRNA cargo in response to HIV infection and substance abuse.

Sharma H, Chinnappan M, Agarwal S, Dalvi P, Gunewardena S, O'Brien-Ladner A, Dhillon NK.

FASEB J. 2018 Sep;32(9):5174-5185. doi: 10.1096/fj.201701558R. Epub 2018 Apr 19.

11.

Pleiotropic Role of p53 in Injury and Liver Regeneration after Acetaminophen Overdose.

Borude P, Bhushan B, Gunewardena S, Akakpo J, Jaeschke H, Apte U.

Am J Pathol. 2018 Jun;188(6):1406-1418. doi: 10.1016/j.ajpath.2018.03.006. Epub 2018 Apr 11.

12.

Differential Gene Expression and Pathway Analysis in Juvenile Nasopharyngeal Angiofibroma Using RNA Sequencing.

Jones JW, Usman S, New J, Holcomb A, Gunewardena S, Tawfik O, Hoover L, Bruegger D, Thomas SM.

Otolaryngol Head Neck Surg. 2018 Sep;159(3):572-575. doi: 10.1177/0194599818769879. Epub 2018 Apr 10.

PMID:
29634432
13.

Relative Abundance of Integrant-Derived Viral RNAs in Infected Tissues Harvested from Chronic Hepatitis B Virus Carriers.

Freitas N, Lukash T, Gunewardena S, Chappell B, Slagle BL, Gudima SO.

J Virol. 2018 Apr 27;92(10). pii: e02221-17. doi: 10.1128/JVI.02221-17. Print 2018 May 15.

14.

Development and Characterization of an In Vitro Model for Radiation-Induced Fibrosis.

Kumar D, Yalamanchali S, New J, Parsel S, New N, Holcomb A, Gunewardena S, Tawfik O, Lominska C, Kimler BF, Anant S, Kakarala K, Tsue T, Shnayder Y, Sykes K, Padhye S, Thomas SM.

Radiat Res. 2018 Mar;189(3):326-336. doi: 10.1667/RR14926.1. Epub 2018 Jan 19.

15.

Motor, Somatosensory, Viscerosensory and Metabolic Impairments in a Heterozygous Female Rat Model of Rett Syndrome.

Bhattacherjee A, Winter MK, Eggimann LS, Mu Y, Gunewardena S, Liao Z, Christianson JA, Smith PG.

Int J Mol Sci. 2017 Dec 29;19(1). pii: E97. doi: 10.3390/ijms19010097.

16.

Neuronal cytoskeletal gene dysregulation and mechanical hypersensitivity in a rat model of Rett syndrome.

Bhattacherjee A, Mu Y, Winter MK, Knapp JR, Eggimann LS, Gunewardena SS, Kobayashi K, Kato S, Krizsan-Agbas D, Smith PG.

Proc Natl Acad Sci U S A. 2017 Aug 15;114(33):E6952-E6961. doi: 10.1073/pnas.1618210114. Epub 2017 Jul 31.

17.

Circulating microRNA as candidates for early embryonic viability in cattle.

Pohler KG, Green JA, Moley LA, Gunewardena S, Hung WT, Payton RR, Hong X, Christenson LK, Geary TW, Smith MF.

Mol Reprod Dev. 2017 Aug;84(8):731-743. doi: 10.1002/mrd.22856.

18.

Vitamin D Impacts the Expression of Runx2 Target Genes and Modulates Inflammation, Oxidative Stress and Membrane Vesicle Biogenesis Gene Networks in 143B Osteosarcoma Cells.

Garimella R, Tadikonda P, Tawfik O, Gunewardena S, Rowe P, Van Veldhuizen P.

Int J Mol Sci. 2017 Mar 16;18(3). pii: E642. doi: 10.3390/ijms18030642.

19.

Genetic redundancy of GATA factors in the extraembryonic trophoblast lineage ensures the progression of preimplantation and postimplantation mammalian development.

Home P, Kumar RP, Ganguly A, Saha B, Milano-Foster J, Bhattacharya B, Ray S, Gunewardena S, Paul A, Camper SA, Fields PE, Paul S.

Development. 2017 Mar 1;144(5):876-888. doi: 10.1242/dev.145318.

20.

The histone demethylase KDM4B regulates peritoneal seeding of ovarian cancer.

Wilson C, Qiu L, Hong Y, Karnik T, Tadros G, Mau B, Ma T, Mu Y, New J, Louie RJ, Gunewardena S, Godwin AK, Tawfik OW, Chien J, Roby KF, Krieg AJ.

Oncogene. 2017 May 4;36(18):2565-2576. doi: 10.1038/onc.2016.412. Epub 2016 Nov 21.

21.

Characterization and Small RNA Content of Extracellular Vesicles in Follicular Fluid of Developing Bovine Antral Follicles.

Navakanitworakul R, Hung WT, Gunewardena S, Davis JS, Chotigeat W, Christenson LK.

Sci Rep. 2016 May 9;6:25486. doi: 10.1038/srep25486.

22.

The role of hepatocyte nuclear factor 4-alpha in perfluorooctanoic acid- and perfluorooctanesulfonic acid-induced hepatocellular dysfunction.

Beggs KM, McGreal SR, McCarthy A, Gunewardena S, Lampe JN, Lau C, Apte U.

Toxicol Appl Pharmacol. 2016 Aug 1;304:18-29. doi: 10.1016/j.taap.2016.05.001. Epub 2016 May 3.

23.

Bile acids promote diethylnitrosamine-induced hepatocellular carcinoma via increased inflammatory signaling.

Sun L, Beggs K, Borude P, Edwards G, Bhushan B, Walesky C, Roy N, Manley MW Jr, Gunewardena S, O'Neil M, Li H, Apte U.

Am J Physiol Gastrointest Liver Physiol. 2016 Jul 1;311(1):G91-G104. doi: 10.1152/ajpgi.00027.2015. Epub 2016 May 5.

24.

Deciphering the Developmental Dynamics of the Mouse Liver Transcriptome.

Gunewardena SS, Yoo B, Peng L, Lu H, Zhong X, Klaassen CD, Cui JY.

PLoS One. 2015 Oct 23;10(10):e0141220. doi: 10.1371/journal.pone.0141220. eCollection 2015.

25.

PI3K/AKT/mTOR and sonic hedgehog pathways cooperate together to inhibit human pancreatic cancer stem cell characteristics and tumor growth.

Sharma N, Nanta R, Sharma J, Gunewardena S, Singh KP, Shankar S, Srivastava RK.

Oncotarget. 2015 Oct 13;6(31):32039-60. doi: 10.18632/oncotarget.5055.

26.
27.

Coding and noncoding expression patterns associated with rare obesity-related disorders: Prader-Willi and Alström syndromes.

Butler MG, Wang K, Marshall JD, Naggert JK, Rethmeyer JA, Gunewardena SS, Manzardo AM.

Adv Genomics Genet. 2015;2015(5):53-75.

28.

Functional coupling of ATP-binding cassette transporter Abcb6 to cytochrome P450 expression and activity in liver.

Chavan H, Li F, Tessman R, Mickey K, Dorko K, Schmitt T, Kumer S, Gunewardena S, Gaikwad N, Krishnamurthy P.

J Biol Chem. 2015 Mar 20;290(12):7871-86. doi: 10.1074/jbc.M114.605386. Epub 2015 Jan 26.

29.

Gonadotrope-specific deletion of Dicer results in severely suppressed gonadotropins and fertility defects.

Wang H, Graham I, Hastings R, Gunewardena S, Brinkmeier ML, Conn PM, Camper SA, Kumar TR.

J Biol Chem. 2015 Jan 30;290(5):2699-714. doi: 10.1074/jbc.M114.621565. Epub 2014 Dec 18.

30.

MicroRNA Expression can be a Promising Strategy for the Detection of Barrett's Esophagus: A Pilot Study.

Bansal A, Hong X, Lee IH, Krishnadath KK, Mathur SC, Gunewardena S, Rastogi A, Sharma P, Christenson LK.

Clin Transl Gastroenterol. 2014 Dec 11;5:e65. doi: 10.1038/ctg.2014.17.

31.

BRCA1 regulation of epidermal growth factor receptor (EGFR) expression in human breast cancer cells involves microRNA-146a and is critical for its tumor suppressor function.

Kumaraswamy E, Wendt KL, Augustine LA, Stecklein SR, Sibala EC, Li D, Gunewardena S, Jensen RA.

Oncogene. 2015 Aug 13;34(33):4333-46. doi: 10.1038/onc.2014.363. Epub 2014 Nov 24.

32.

Altered gene expression patterns during the initiation and promotion stages of neonatally diethylstilbestrol-induced hyperplasia/dysplasia/neoplasia in the hamster uterus.

Hendry WJ, Hariri HY, Alwis ID, Gunewardena SS, Hendry IR.

Reprod Toxicol. 2014 Dec;50:68-86. doi: 10.1016/j.reprotox.2014.09.002. Epub 2014 Sep 19.

33.

Exon microarray analysis of human dorsolateral prefrontal cortex in alcoholism.

Manzardo AM, Gunewardena S, Wang K, Butler MG.

Alcohol Clin Exp Res. 2014 Jun;38(6):1594-601. doi: 10.1111/acer.12429. Epub 2014 May 30.

34.

PKCλ/ι signaling promotes triple-negative breast cancer growth and metastasis.

Paul A, Gunewardena S, Stecklein SR, Saha B, Parelkar N, Danley M, Rajendran G, Home P, Ray S, Jokar I, Vielhauer GA, Jensen RA, Tawfik O, Paul S.

Cell Death Differ. 2014 Sep;21(9):1469-81. doi: 10.1038/cdd.2014.62. Epub 2014 May 2.

35.

Auranofin induces lethal oxidative and endoplasmic reticulum stress and exerts potent preclinical activity against chronic lymphocytic leukemia.

Fiskus W, Saba N, Shen M, Ghias M, Liu J, Gupta SD, Chauhan L, Rao R, Gunewardena S, Schorno K, Austin CP, Maddocks K, Byrd J, Melnick A, Huang P, Wiestner A, Bhalla KN.

Cancer Res. 2014 May 1;74(9):2520-32. doi: 10.1158/0008-5472.CAN-13-2033. Epub 2014 Mar 5.

36.

RNA-sequencing quantification of hepatic ontogeny of phase-I enzymes in mice.

Peng L, Cui JY, Yoo B, Gunewardena SS, Lu H, Klaassen CD, Zhong XB.

Drug Metab Dispos. 2013 Dec;41(12):2175-86. doi: 10.1124/dmd.113.054635. Epub 2013 Sep 30.

37.

Cell-specific post-transcriptional regulation of γ-synuclein gene by micro-RNAs.

Surgucheva I, Gunewardena S, Rao HS, Surguchov A.

PLoS One. 2013 Sep 11;8(9):e73786. doi: 10.1371/journal.pone.0073786. eCollection 2013.

38.
39.

Research resource: preovulatory LH surge effects on follicular theca and granulosa transcriptomes.

Christenson LK, Gunewardena S, Hong X, Spitschak M, Baufeld A, Vanselow J.

Mol Endocrinol. 2013 Jul;27(7):1153-71. doi: 10.1210/me.2013-1093. Epub 2013 May 28.

40.

RNA-sequencing quantification of hepatic ontogeny and tissue distribution of mRNAs of phase II enzymes in mice.

Lu H, Gunewardena S, Cui JY, Yoo B, Zhong XB, Klaassen CD.

Drug Metab Dispos. 2013 Apr;41(4):844-57. doi: 10.1124/dmd.112.050211. Epub 2013 Feb 4.

41.

Hepatocyte nuclear factor 4 alpha deletion promotes diethylnitrosamine-induced hepatocellular carcinoma in rodents.

Walesky C, Edwards G, Borude P, Gunewardena S, O'Neil M, Yoo B, Apte U.

Hepatology. 2013 Jun;57(6):2480-90. doi: 10.1002/hep.26251.

42.

Loss of the repressor REST in uterine fibroids promotes aberrant G protein-coupled receptor 10 expression and activates mammalian target of rapamycin pathway.

Varghese BV, Koohestani F, McWilliams M, Colvin A, Gunewardena S, Kinsey WH, Nowak RA, Nothnick WB, Chennathukuzhi VM.

Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2187-92. doi: 10.1073/pnas.1215759110. Epub 2013 Jan 2.

43.

Hepatocyte-specific deletion of hepatocyte nuclear factor-4α in adult mice results in increased hepatocyte proliferation.

Walesky C, Gunewardena S, Terwilliger EF, Edwards G, Borude P, Apte U.

Am J Physiol Gastrointest Liver Physiol. 2013 Jan 1;304(1):G26-37. doi: 10.1152/ajpgi.00064.2012. Epub 2012 Oct 25.

44.

An RNA interference lethality screen of the human druggable genome to identify molecular vulnerabilities in epithelial ovarian cancer.

Sethi G, Pathak HB, Zhang H, Zhou Y, Einarson MB, Vathipadiekal V, Gunewardena S, Birrer MJ, Godwin AK.

PLoS One. 2012;7(10):e47086. doi: 10.1371/journal.pone.0047086. Epub 2012 Oct 9.

45.

Hepatic ontogeny and tissue distribution of mRNAs of epigenetic modifiers in mice using RNA-sequencing.

Lu H, Cui JY, Gunewardena S, Yoo B, Zhong XB, Klaassen CD.

Epigenetics. 2012 Aug;7(8):914-29. doi: 10.4161/epi.21113. Epub 2012 Jul 9.

46.

Altered subcellular localization of transcription factor TEAD4 regulates first mammalian cell lineage commitment.

Home P, Saha B, Ray S, Dutta D, Gunewardena S, Yoo B, Pal A, Vivian JL, Larson M, Petroff M, Gallagher PG, Schulz VP, White KL, Golos TG, Behr B, Paul S.

Proc Natl Acad Sci U S A. 2012 May 8;109(19):7362-7. doi: 10.1073/pnas.1201595109. Epub 2012 Apr 23.

47.

RNA-Seq reveals different mRNA abundance of transporters and their alternative transcript isoforms during liver development.

Cui JY, Gunewardena SS, Yoo B, Liu J, Renaud HJ, Lu H, Zhong XB, Klaassen CD.

Toxicol Sci. 2012 Jun;127(2):592-608. doi: 10.1093/toxsci/kfs107. Epub 2012 Mar 27.

48.

RNA sequencing reveals dynamic changes of mRNA abundance of cytochromes P450 and their alternative transcripts during mouse liver development.

Peng L, Yoo B, Gunewardena SS, Lu H, Klaassen CD, Zhong XB.

Drug Metab Dispos. 2012 Jun;40(6):1198-209. doi: 10.1124/dmd.112.045088. Epub 2012 Mar 20.

49.

Yes-associated protein is involved in proliferation and differentiation during postnatal liver development.

Septer S, Edwards G, Gunewardena S, Wolfe A, Li H, Daniel J, Apte U.

Am J Physiol Gastrointest Liver Physiol. 2012 Mar 1;302(5):G493-503. doi: 10.1152/ajpgi.00056.2011. Epub 2011 Dec 22.

50.

ChIPing the cistrome of PXR in mouse liver.

Cui JY, Gunewardena SS, Rockwell CE, Klaassen CD.

Nucleic Acids Res. 2010 Dec;38(22):7943-63. doi: 10.1093/nar/gkq654. Epub 2010 Aug 6.

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