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Items: 22


Correction to: A phase I study of LY3164530, a bispecific antibody targeting MET and EGFR, in patients with advanced or metastatic cancer.

Patnaik A, Gordon M, Tsai F, Papadopoulos KP, Rasco D, Beeram M, Fu S, Janku F, Hynes SM, Gundala SR, Willard MD, Zhang W, Lin AB, Hong D.

Cancer Chemother Pharmacol. 2018 Sep;82(3):419. doi: 10.1007/s00280-018-3641-5.


A phase I study of LY3164530, a bispecific antibody targeting MET and EGFR, in patients with advanced or metastatic cancer.

Patnaik A, Gordon M, Tsai F, Papadopoulos KP, Rasco D, Beeram M, Fu S, Janku F, Hynes SM, Gundala SR, Willard MD, Zhang W, Lin AB, Hong D.

Cancer Chemother Pharmacol. 2018 Sep;82(3):407-418. doi: 10.1007/s00280-018-3623-7. Epub 2018 Jun 20. Erratum in: Cancer Chemother Pharmacol. 2018 Jul 16;:. Papadopoulous, Kyri [corrected to Papadopoulos, Kyriakos P] and Beeram, S Muralidhar [corrected to Beeram, Muralidhar].


Pharmacokinetic-pharmacodynamic correlations in the development of ginger extract as an anticancer agent.

Mukkavilli R, Yang C, Tanwar RS, Saxena R, Gundala SR, Zhang Y, Ghareeb A, Floyd SD, Vangala S, Kuo WW, Rida PCG, Aneja R.

Sci Rep. 2018 Feb 14;8(1):3056. doi: 10.1038/s41598-018-21125-2.


Preclinical Development of a Nontoxic Oral Formulation of Monoethanolamine, a Lipid Precursor, for Prostate Cancer Treatment.

Saxena R, Yang C, Rao M, Turaga RC, Garlapati C, Gundala SR, Myers K, Ghareeb A, Bhattarai S, Kamalinia G, Bristi S, Su D, Gadda G, Rida PCG, Cantuaria GH, Aneja R.

Clin Cancer Res. 2017 Jul 15;23(14):3781-3793. doi: 10.1158/1078-0432.CCR-16-1716. Epub 2017 Feb 6.


Preclinical Evaluation of DMA, a Bisbenzimidazole, as Radioprotector: Toxicity, Pharmacokinetics, and Biodistribution Studies in Balb/c Mice.

Nimesh H, Tiwari V, Yang C, Gundala SR, Chuttani K, Hazari PP, Mishra AK, Sharma A, Lal J, Katyal A, Aneja R, Tandon V.

Mol Pharmacol. 2015 Oct;88(4):768-78. doi: 10.1124/mol.115.098376. Epub 2015 Aug 3. Erratum in: Mol Pharmacol. 2015 Oct;88(4):813.


Noscapine recirculates enterohepatically and induces self-clearance.

Mukkavilli R, Gundala SR, Yang C, Jadhav GR, Vangala S, Reid MD, Aneja R.

Eur J Pharm Sci. 2015 Sep 18;77:90-9. doi: 10.1016/j.ejps.2015.05.026. Epub 2015 May 28.


Design, synthesis and biological evaluation of di-substituted noscapine analogs as potent and microtubule-targeted anticancer agents.

Mishra RC, Gundala SR, Karna P, Lopus M, Gupta KK, Nagaraju M, Hamelberg D, Tandon V, Panda D, Reid MD, Aneja R.

Bioorg Med Chem Lett. 2015;25(10):2133-40. doi: 10.1016/j.bmcl.2015.03.076. Epub 2015 Mar 31.


Synergistic interactions among flavonoids and acetogenins in Graviola (Annona muricata) leaves confer protection against prostate cancer.

Yang C, Gundala SR, Mukkavilli R, Vangala S, Reid MD, Aneja R.

Carcinogenesis. 2015 Jun;36(6):656-65. doi: 10.1093/carcin/bgv046. Epub 2015 Apr 11.


Cyclodextrin complexes of reduced bromonoscapine in guar gum microspheres enhance colonic drug delivery.

Madan J, Gundala SR, Baruah B, Nagaraju M, Yates C, Turner T, Rangari V, Hamelberg D, Reid MD, Aneja R.

Mol Pharm. 2014 Dec 1;11(12):4339-49. doi: 10.1021/mp500408n. Epub 2014 Nov 18.


Modulation of cytochrome P450 metabolism and transport across intestinal epithelial barrier by ginger biophenolics.

Mukkavilli R, Gundala SR, Yang C, Donthamsetty S, Cantuaria G, Jadhav GR, Vangala S, Reid MD, Aneja R.

PLoS One. 2014 Sep 24;9(9):e108386. doi: 10.1371/journal.pone.0108386. eCollection 2014.


Novel third-generation water-soluble noscapine analogs as superior microtubule-interfering agents with enhanced antiproliferative activity.

Henary M, Narayana L, Ahad S, Gundala SR, Mukkavilli R, Sharma V, Owens EA, Yadav Y, Nagaraju M, Hamelberg D, Tandon V, Panda D, Aneja R.

Biochem Pharmacol. 2014 Nov 15;92(2):192-205. doi: 10.1016/j.bcp.2014.07.020. Epub 2014 Aug 11.


Hydroxychavicol, a betel leaf component, inhibits prostate cancer through ROS-driven DNA damage and apoptosis.

Gundala SR, Yang C, Mukkavilli R, Paranjpe R, Brahmbhatt M, Pannu V, Cheng A, Reid MD, Aneja R.

Toxicol Appl Pharmacol. 2014 Oct 1;280(1):86-96. doi: 10.1016/j.taap.2014.07.012. Epub 2014 Jul 23.


Enhanced noscapine delivery using estrogen-receptor-targeted nanoparticles for breast cancer therapy.

Madan J, Gundala SR, Kasetti Y, Bharatam PV, Aneja R, Katyal A, Jain UK.

Anticancer Drugs. 2014 Jul;25(6):704-16. doi: 10.1097/CAD.0000000000000098.


Piper betel leaf: a reservoir of potential xenohormetic nutraceuticals with cancer-fighting properties.

Gundala SR, Aneja R.

Cancer Prev Res (Phila). 2014 May;7(5):477-86. doi: 10.1158/1940-6207.CAPR-13-0355. Epub 2014 Jan 21. Review.


Enterohepatic recirculation of bioactive ginger phytochemicals is associated with enhanced tumor growth-inhibitory activity of ginger extract.

Gundala SR, Mukkavilli R, Yang C, Yadav P, Tandon V, Vangala S, Prakash S, Aneja R.

Carcinogenesis. 2014 Jun;35(6):1320-9. doi: 10.1093/carcin/bgu011. Epub 2014 Jan 15.


Polar biophenolics in sweet potato greens extract synergize to inhibit prostate cancer cell proliferation and in vivo tumor growth.

Gundala SR, Yang C, Lakshminarayana N, Asif G, Gupta MV, Shamsi S, Aneja R.

Carcinogenesis. 2013 Sep;34(9):2039-49. doi: 10.1093/carcin/bgt141. Epub 2013 Apr 29.


Ginger phytochemicals exhibit synergy to inhibit prostate cancer cell proliferation.

Brahmbhatt M, Gundala SR, Asif G, Shamsi SA, Aneja R.

Nutr Cancer. 2013;65(2):263-72. doi: 10.1080/01635581.2013.749925.


Piper betel leaf extract: anticancer benefits and bio-guided fractionation to identify active principles for prostate cancer management.

Paranjpe R, Gundala SR, Lakshminarayana N, Sagwal A, Asif G, Pandey A, Aneja R.

Carcinogenesis. 2013 Jul;34(7):1558-66. doi: 10.1093/carcin/bgt066. Epub 2013 Feb 21.


Polyphenol-rich sweet potato greens extract inhibits proliferation and induces apoptosis in prostate cancer cells in vitro and in vivo.

Karna P, Gundala SR, Gupta MV, Shamsi SA, Pace RD, Yates C, Narayan S, Aneja R.

Carcinogenesis. 2011 Dec;32(12):1872-80. doi: 10.1093/carcin/bgr215. Epub 2011 Sep 26.


Benefits of whole ginger extract in prostate cancer.

Karna P, Chagani S, Gundala SR, Rida PC, Asif G, Sharma V, Gupta MV, Aneja R.

Br J Nutr. 2012 Feb;107(4):473-84. doi: 10.1017/S0007114511003308. Epub 2011 Aug 18.


Second generation benzofuranone ring substituted noscapine analogs: synthesis and biological evaluation.

Mishra RC, Karna P, Gundala SR, Pannu V, Stanton RA, Gupta KK, Robinson MH, Lopus M, Wilson L, Henary M, Aneja R.

Biochem Pharmacol. 2011 Jul 15;82(2):110-21. doi: 10.1016/j.bcp.2011.03.029. Epub 2011 Apr 8.


The first low microM SecA inhibitors.

Chen W, Huang YJ, Gundala SR, Yang H, Li M, Tai PC, Wang B.

Bioorg Med Chem. 2010 Feb 15;18(4):1617-25. doi: 10.1016/j.bmc.2009.12.074. Epub 2010 Jan 6.

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