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Items: 32

1.

A downscaling-disaggregation approach for developing IDF curves in arid regions.

Uraba MB, Gunawardhana LN, Al-Rawas GA, Baawain MS.

Environ Monit Assess. 2019 Mar 26;191(4):245. doi: 10.1007/s10661-019-7385-4.

PMID:
30915584
2.

Cardiovascular Safety of Febuxostat.

White WB, Gunawardhana L.

N Engl J Med. 2018 Oct 18;379(16):1584. doi: 10.1056/NEJMc1809736. No abstract available.

PMID:
30332566
3.

Efficacy and Safety of Febuxostat Extended and Immediate Release in Patients With Gout and Renal Impairment: A Phase III Placebo-Controlled Study.

Saag KG, Becker MA, Whelton A, Hunt B, Castillo M, Kisfalvi K, Gunawardhana L.

Arthritis Rheumatol. 2019 Jan;71(1):143-153. doi: 10.1002/art.40685.

4.

Efficacy and safety of febuxostat extended release and immediate release in patients with gout and moderate renal impairment: phase II placebo-controlled study.

Gunawardhana L, Becker MA, Whelton A, Hunt B, Castillo M, Saag K.

Arthritis Res Ther. 2018 May 30;20(1):99. doi: 10.1186/s13075-018-1593-0.

5.

Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout.

White WB, Saag KG, Becker MA, Borer JS, Gorelick PB, Whelton A, Hunt B, Castillo M, Gunawardhana L; CARES Investigators.

N Engl J Med. 2018 Mar 29;378(13):1200-1210. doi: 10.1056/NEJMoa1710895. Epub 2018 Mar 12.

6.

Effect of Febuxostat on Ambulatory Blood Pressure in Subjects With Hyperuricemia and Hypertension: A Phase 2 Randomized Placebo-Controlled Study.

Gunawardhana L, McLean L, Punzi HA, Hunt B, Palmer RN, Whelton A, Feig DI.

J Am Heart Assoc. 2017 Nov 4;6(11). pii: e006683. doi: 10.1161/JAHA.117.006683.

7.

Effects of Febuxostat in Early Gout: A Randomized, Double-Blind, Placebo-Controlled Study.

Dalbeth N, Saag KG, Palmer WE, Choi HK, Hunt B, MacDonald PA, Thienel U, Gunawardhana L.

Arthritis Rheumatol. 2017 Dec;69(12):2386-2395. doi: 10.1002/art.40233.

8.

Reply.

Saag K, Gunawardhana L.

Arthritis Rheumatol. 2016 Oct;68(10):2564. doi: 10.1002/art.39768. No abstract available.

9.

Impact of Febuxostat on Renal Function in Gout Patients With Moderate-to-Severe Renal Impairment.

Saag KG, Whelton A, Becker MA, MacDonald P, Hunt B, Gunawardhana L.

Arthritis Rheumatol. 2016 Aug;68(8):2035-43. doi: 10.1002/art.39654.

10.

Assessment of future variability in extreme precipitation and the potential effects on the wadi flow regime.

Gunawardhana LN, Al-Rawas GA, Kazama S, Al-Najar KA.

Environ Monit Assess. 2015 Oct;187(10):626. doi: 10.1007/s10661-015-4851-5. Epub 2015 Sep 14.

PMID:
26370197
11.

Characteristic DNA methylation profiles in peripheral blood monocytes are associated with inflammatory phenotypes of asthma.

Gunawardhana LP, Gibson PG, Simpson JL, Benton MC, Lea RA, Baines KJ.

Epigenetics. 2014 Sep;9(9):1302-16. doi: 10.4161/epi.33066. Epub 2014 Aug 11.

12.

Activity and expression of histone acetylases and deacetylases in inflammatory phenotypes of asthma.

Gunawardhana LP, Gibson PG, Simpson JL, Powell H, Baines KJ.

Clin Exp Allergy. 2014 Jan;44(1):47-57. doi: 10.1111/cea.12168.

PMID:
24355018
13.

Differential DNA methylation profiles of infants exposed to maternal asthma during pregnancy.

Gunawardhana LP, Baines KJ, Mattes J, Murphy VE, Simpson JL, Gibson PG.

Pediatr Pulmonol. 2014 Sep;49(9):852-62. doi: 10.1002/ppul.22930. Epub 2013 Oct 25.

PMID:
24166889
14.

Elevated expression of the NLRP3 inflammasome in neutrophilic asthma.

Simpson JL, Phipps S, Baines KJ, Oreo KM, Gunawardhana L, Gibson PG.

Eur Respir J. 2014 Apr;43(4):1067-76. doi: 10.1183/09031936.00105013. Epub 2013 Oct 17.

15.

Randomized controlled trial of febuxostat versus allopurinol or placebo in individuals with higher urinary uric acid excretion and calcium stones.

Goldfarb DS, MacDonald PA, Gunawardhana L, Chefo S, McLean L.

Clin J Am Soc Nephrol. 2013 Nov;8(11):1960-7. doi: 10.2215/CJN.01760213. Epub 2013 Aug 8.

16.

Preservation of renal function during gout treatment with febuxostat: a quantitative study.

Whelton A, MacDonald PA, Chefo S, Gunawardhana L.

Postgrad Med. 2013 Jan;125(1):106-14. doi: 10.3810/pgm.2013.01.2626.

PMID:
23391676
17.

Novel immune genes associated with excessive inflammatory and antiviral responses to rhinovirus in COPD.

Baines KJ, Hsu AC, Tooze M, Gunawardhana LP, Gibson PG, Wark PA.

Respir Res. 2013 Feb 6;14:15. doi: 10.1186/1465-9921-14-15.

18.

The effects of xanthine oxidase inhibition by febuxostat on the pharmacokinetics of theophylline.

Tsai M, Wu JT, Gunawardhana L, Naik H.

Int J Clin Pharmacol Ther. 2012 May;50(5):331-7.

PMID:
22541837
19.

Treating hyperuricemia of gout: safety and efficacy of febuxostat and allopurinol in older versus younger subjects.

Becker MA, MacDonald PA, Hunt B, Gunawardhana L.

Nucleosides Nucleotides Nucleic Acids. 2011 Dec;30(12):1011-7. doi: 10.1080/15257770.2011.603715.

PMID:
22132950
20.

Febuxostat in gout: serum urate response in uric acid overproducers and underexcretors.

Goldfarb DS, MacDonald PA, Hunt B, Gunawardhana L.

J Rheumatol. 2011 Jul;38(7):1385-9. doi: 10.3899/jrheum.101156. Epub 2011 May 15.

PMID:
21572152
21.

Different inflammatory phenotypes in adults and children with acute asthma.

Wang F, He XY, Baines KJ, Gunawardhana LP, Simpson JL, Li F, Gibson PG.

Eur Respir J. 2011 Sep;38(3):567-74. doi: 10.1183/09031936.00170110. Epub 2011 Jan 13.

22.

Renal function in gout: long-term treatment effects of febuxostat.

Whelton A, Macdonald PA, Zhao L, Hunt B, Gunawardhana L.

J Clin Rheumatol. 2011 Jan;17(1):7-13. doi: 10.1097/RHU.0b013e318204aab4.

PMID:
21169856
23.

The CD-loop of PAI-2 (SERPINB2) is redundant in the targeting, inhibition and clearance of cell surface uPA activity.

Cochran BJ, Gunawardhana LP, Vine KL, Lee JA, Lobov S, Ranson M.

BMC Biotechnol. 2009 May 14;9:43. doi: 10.1186/1472-6750-9-43.

25.

1,2-Dichlorobenzene-mediated hepatocellular oxidative stress in Fischer-344 and Sprague-Dawley rats.

Younis HS, Hoglen NC, Kuester RK, Gunawardhana L, Sipes IG.

Toxicol Appl Pharmacol. 2000 Mar 1;163(2):141-8.

PMID:
10698672
26.

1,2-Dichlorobenzene-induced lipid peroxidation in male Fischer 344 rats is Kupffer cell dependent.

Hoglen NC, Younis HS, Hartley DP, Gunawardhana L, Lantz RC, Sipes IG.

Toxicol Sci. 1998 Dec;46(2):376-85.

PMID:
10048141
27.

The liver as a target for chemical-chemical interactions.

Sauer JM, Stine ER, Gunawardhana L, Hill DA, Sipes IG.

Adv Pharmacol. 1997;43:37-63. Review. No abstract available.

PMID:
9342172
28.
29.
30.

The N-acetylation of sulfamethazine and p-aminobenzoic acid by human liver slices in dynamic organ culture.

Gunawardhana L, Barr J, Weir AJ, Brendel K, Sipes IG.

Drug Metab Dispos. 1991 May-Jun;19(3):648-54.

PMID:
1680632
31.

Dichlorobenzene hepatotoxicity strain differences and structure activity relationships.

Gunawardhana L, Sipes IG.

Adv Exp Med Biol. 1991;283:731-4. No abstract available.

PMID:
2069048
32.

Liver slices: an in vitro system for determination of N-acetylation in human liver.

Gunawardhana L, Barr J, Weir AJ, Brendel K, Sipes IG.

Proc West Pharmacol Soc. 1988;31:137-41. No abstract available.

PMID:
3264914

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