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Items: 26


Follicle-Stimulating Hormone Receptor Is Expressed by Most Ovarian Cancer Subtypes and Is a Safe and Effective Immunotherapeutic Target.

Perales-Puchalt A, Svoronos N, Rutkowski MR, Allegrezza MJ, Tesone AJ, Payne KK, Wickramasinghe J, Nguyen JM, O'Brien SW, Gumireddy K, Huang Q, Cadungog MG, Connolly DC, Tchou J, Curiel TJ, Conejo-Garcia JR.

Clin Cancer Res. 2017 Jan 15;23(2):441-453. doi: 10.1158/1078-0432.CCR-16-0492. Epub 2016 Jul 19.


The mRNA-edited form of GABRA3 suppresses GABRA3-mediated Akt activation and breast cancer metastasis.

Gumireddy K, Li A, Kossenkov AV, Sakurai M, Yan J, Li Y, Xu H, Wang J, Zhang PJ, Zhang L, Showe LC, Nishikura K, Huang Q.

Nat Commun. 2016 Feb 12;7:10715. doi: 10.1038/ncomms10715.


Isolation of Protein Complexes Associated with Long Noncoding RNAs.

Gumireddy K, Yan J, Huang Q.

Methods Mol Biol. 2016;1402:27-32. doi: 10.1007/978-1-4939-3378-5_4.


AKAP4 is a circulating biomarker for non-small cell lung cancer.

Gumireddy K, Li A, Chang DH, Liu Q, Kossenkov AV, Yan J, Korst RJ, Nam BT, Xu H, Zhang L, Ganepola GA, Showe LC, Huang Q.

Oncotarget. 2015 Jul 10;6(19):17637-47.


ZBRK1, a novel tumor suppressor, activates VHL gene transcription through formation of a complex with VHL and p300 in renal cancer.

Chen K, Yu G, Gumireddy K, Li A, Yao W, Gao L, Chen S, Hao J, Wang J, Huang Q, Xu H, Ye Z.

Oncotarget. 2015 Mar 30;6(9):6959-76.


Pseudogene PTENP1 functions as a competing endogenous RNA to suppress clear-cell renal cell carcinoma progression.

Yu G, Yao W, Gumireddy K, Li A, Wang J, Xiao W, Chen K, Xiao H, Li H, Tang K, Ye Z, Huang Q, Xu H.

Mol Cancer Ther. 2014 Dec;13(12):3086-97. doi: 10.1158/1535-7163.MCT-14-0245. Epub 2014 Sep 23.


ID1 promotes breast cancer metastasis by S100A9 regulation.

Gumireddy K, Li A, Kossenkov AV, Cai KQ, Liu Q, Yan J, Xu H, Showe L, Zhang L, Huang Q.

Mol Cancer Res. 2014 Sep;12(9):1334-43. doi: 10.1158/1541-7786.MCR-14-0049. Epub 2014 Jun 19.


miRNA-34a suppresses cell proliferation and metastasis by targeting CD44 in human renal carcinoma cells.

Yu G, Li H, Wang J, Gumireddy K, Li A, Yao W, Tang K, Xiao W, Hu J, Xiao H, Lang B, Ye Z, Huang Q, Xu H.

J Urol. 2014 Oct;192(4):1229-37. doi: 10.1016/j.juro.2014.05.094. Epub 2014 May 24.


NOV-002, A Glutathione Disulfide Mimetic, Suppresses Tumor Cell Invasion and Metastasis.

Gumireddy K, Li A, Cao L, Yan J, Liu L, Xu X, Pazoles C, Huang Q.

J Carcinog Mutagen. 2013 Apr 30;2013. pii: S7-002.


Regulation of mesenchymal phenotype by MicroRNAs in cancer.

Yan J, Gumireddy K, Li A, Huang Q.

Curr Cancer Drug Targets. 2013 Nov;13(9):930-4. Review.


Identification of a long non-coding RNA-associated RNP complex regulating metastasis at the translational step.

Gumireddy K, Li A, Yan J, Setoyama T, Johannes GJ, Orom UA, Tchou J, Liu Q, Zhang L, Speicher DW, Calin GA, Huang Q.

EMBO J. 2013 Oct 16;32(20):2672-84. doi: 10.1038/emboj.2013.188. Epub 2013 Aug 23.


Long noncoding RNAs with enhancer-like function in human cells.

Ørom UA, Derrien T, Beringer M, Gumireddy K, Gardini A, Bussotti G, Lai F, Zytnicki M, Notredame C, Huang Q, Guigo R, Shiekhattar R.

Cell. 2010 Oct 1;143(1):46-58. doi: 10.1016/j.cell.2010.09.001.


Identification of metastasis genes by a functional genomics approach.

Gumireddy K, Huang Q.

Cell Cycle. 2010 Feb 1;9(3):423. Epub 2010 Feb 17. No abstract available.


KLF17 is a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer.

Gumireddy K, Li A, Gimotty PA, Klein-Szanto AJ, Showe LC, Katsaros D, Coukos G, Zhang L, Huang Q.

Nat Cell Biol. 2009 Nov;11(11):1297-304. doi: 10.1038/ncb1974. Epub 2009 Oct 4.


Small-molecule inhibitors of microrna miR-21 function.

Gumireddy K, Young DD, Xiong X, Hogenesch JB, Huang Q, Deiters A.

Angew Chem Int Ed Engl. 2008;47(39):7482-4. doi: 10.1002/anie.200801555. No abstract available.


The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis.

Huang Q, Gumireddy K, Schrier M, le Sage C, Nagel R, Nair S, Egan DA, Li A, Huang G, Klein-Szanto AJ, Gimotty PA, Katsaros D, Coukos G, Zhang L, Puré E, Agami R.

Nat Cell Biol. 2008 Feb;10(2):202-10. doi: 10.1038/ncb1681. Epub 2008 Jan 13.


In vivo selection for metastasis promoting genes in the mouse.

Gumireddy K, Sun F, Klein-Szanto AJ, Gibbins JM, Gimotty PA, Saunders AJ, Schultz PG, Huang Q.

Proc Natl Acad Sci U S A. 2007 Apr 17;104(16):6696-701. Epub 2007 Apr 9.


Free fatty acids produce insulin resistance and activate the proinflammatory nuclear factor-kappaB pathway in rat liver.

Boden G, She P, Mozzoli M, Cheung P, Gumireddy K, Reddy P, Xiang X, Luo Z, Ruderman N.

Diabetes. 2005 Dec;54(12):3458-65.


Novel coumarin-3-(N-aryl)carboxamides arrest breast cancer cell growth by inhibiting ErbB-2 and ERK1.

Reddy NS, Gumireddy K, Mallireddigari MR, Cosenza SC, Venkatapuram P, Bell SC, Reddy EP, Reddy MV.

Bioorg Med Chem. 2005 May 2;13(9):3141-7.


ON01910, a non-ATP-competitive small molecule inhibitor of Plk1, is a potent anticancer agent.

Gumireddy K, Reddy MV, Cosenza SC, Boominathan R, Baker SJ, Papathi N, Jiang J, Holland J, Reddy EP.

Cancer Cell. 2005 Mar;7(3):275-86. Erratum in: Cancer Cell. 2005 May;7(5):497. Boomi Nathan, R [corrected to Boominathan, R].


A non-ATP-competitive inhibitor of BCR-ABL overrides imatinib resistance.

Gumireddy K, Baker SJ, Cosenza SC, John P, Kang AD, Robell KA, Reddy MV, Reddy EP.

Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):1992-7. Epub 2005 Jan 27. Erratum in: Proc Natl Acad Sci U S A. 2005 Apr 12;102(15):5635.


Synthesis of new coumarin 3-(N-aryl) sulfonamides and their anticancer activity.

Reddy NS, Mallireddigari MR, Cosenza S, Gumireddy K, Bell SC, Reddy EP, Reddy MV.

Bioorg Med Chem Lett. 2004 Aug 2;14(15):4093-7.


Mitogen-activated protein kinase pathway mediates DBP-maf-induced apoptosis in RAW 264.7 macrophages.

Gumireddy K, Reddy CD, Swamy N.

J Cell Biochem. 2003 Sep 1;90(1):87-96.


Effect of 20-epi-1alpha,25-dihydroxyvitamin D3 on the proliferation of human neuroblastoma: role of cell cycle regulators and the Myc-Id2 pathway.

Gumireddy K, Ikegaki N, Phillips PC, Sutton LN, Reddy CD.

Biochem Pharmacol. 2003 Jun 15;65(12):1943-55.


Anti-proliferative effects of 20-epi-vitamin-D3 analogue, KH1060 in human neuroblastoma: induction of RAR-beta and p21(Cip1).

Gumireddy K, Reddy GS, Ikegaki N, Binderup L, Sutton LN, Phillips PC, Reddy CD.

Cancer Lett. 2003 Feb 10;190(1):51-60.


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