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Items: 46

1.

Advances in endovascular neuro-oncology: endovascular selective intra-arterial (ESIA) infusion of targeted biologic therapy for brain tumors.

Srinivasan VM, Lang FF, Chen SR, Chen MM, Gumin J, Johnson J, Burkhardt JK, Kan P.

J Neurointerv Surg. 2020 Feb;12(2):197-203. doi: 10.1136/neurintsurg-2019-015137. Epub 2019 Nov 1. Review.

PMID:
31676690
2.

GITRL-armed Delta-24-RGD oncolytic adenovirus prolongs survival and induces anti-glioma immune memory.

Rivera-Molina Y, Jiang H, Fueyo J, Nguyen T, Shin DH, Youssef G, Fan X, Gumin J, Alonso MM, Phadnis S, Lang FF, Gomez-Manzano C.

Neurooncol Adv. 2019 May-Dec;1(1):vdz009. doi: 10.1093/noajnl/vdz009. Epub 2019 Jun 5.

3.

Microcatheter delivery of neurotherapeutics: compatibility with mesenchymal stem cells.

Srinivasan VM, Gumin J, Camstra KM, Chen SR, Johnson JN, Shimizu Y, Parker Kerrigan BC, Shpall EJ, Lang FF, Kan P.

J Neurosurg. 2019 Sep 6:1-9. doi: 10.3171/2019.6.JNS19327. [Epub ahead of print]

PMID:
31491769
4.

REST-DRD2 mechanism impacts glioblastoma stem cell-mediated tumorigenesis.

Marisetty AL, Lu L, Veo BL, Liu B, Coarfa C, Kamal MM, Kassem DH, Irshad K, Lu Y, Gumin J, Henry V, Paulucci-Holthauzen A, Rao G, Baladandayuthapani V, Lang FF, Fuller GN, Majumder S.

Neuro Oncol. 2019 Jun 10;21(6):775-785. doi: 10.1093/neuonc/noz030.

PMID:
30953587
5.

REST overexpression in mice causes deficits in spontaneous locomotion.

Lu L, Marisetty A, Liu B, Kamal MM, Gumin J, Veo B, Cai Y, Kassem DH, Weng C, Maynard ME, Hood KN, Fuller GN, Pan ZZ, Cykowski MD, Dash PK, Majumder S.

Sci Rep. 2018 Aug 14;8(1):12083. doi: 10.1038/s41598-018-29441-3.

6.

A Coclinical Radiogenomic Validation Study: Conserved Magnetic Resonance Radiomic Appearance of Periostin-Expressing Glioblastoma in Patients and Xenograft Models.

Zinn PO, Singh SK, Kotrotsou A, Hassan I, Thomas G, Luedi MM, Elakkad A, Elshafeey N, Idris T, Mosley J, Gumin J, Fuller GN, de Groot JF, Baladandayuthapani V, Sulman EP, Kumar AJ, Sawaya R, Lang FF, Piwnica-Worms D, Colen RR.

Clin Cancer Res. 2018 Dec 15;24(24):6288-6299. doi: 10.1158/1078-0432.CCR-17-3420. Epub 2018 Jul 27.

7.

A gene expression signature predicts recurrence-free survival in meningioma.

Olar A, Goodman LD, Wani KM, Boehling NS, Sharma DS, Mody RR, Gumin J, Claus EB, Lang FF, Cloughesy TF, Lai A, Aldape KD, DeMonte F, Sulman EP.

Oncotarget. 2018 Feb 15;9(22):16087-16098. doi: 10.18632/oncotarget.24498. eCollection 2018 Mar 23.

8.

Glioblastoma stem cell-derived exosomes induce M2 macrophages and PD-L1 expression on human monocytes.

Gabrusiewicz K, Li X, Wei J, Hashimoto Y, Marisetty AL, Ott M, Wang F, Hawke D, Yu J, Healy LM, Hossain A, Akers JC, Maiti SN, Yamashita S, Shimizu Y, Dunner K, Zal MA, Burks JK, Gumin J, Nwajei F, Rezavanian A, Zhou S, Rao G, Sawaya R, Fuller GN, Huse JT, Antel JP, Li S, Cooper L, Sulman EP, Chen C, Geula C, Kalluri R, Zal T, Heimberger AB.

Oncoimmunology. 2018 Jan 16;7(4):e1412909. doi: 10.1080/2162402X.2017.1412909. eCollection 2018.

9.

Magnetic resonance and photoacoustic imaging of brain tumor mediated by mesenchymal stem cell labeled with multifunctional nanoparticle introduced via carotid artery injection.

Qiao Y, Gumin J, MacLellan CJ, Gao F, Bouchard R, Lang FF, Stafford RJ, Melancon MP.

Nanotechnology. 2018 Apr 20;29(16):165101. doi: 10.1088/1361-6528/aaaf16.

10.

Phase I Study of DNX-2401 (Delta-24-RGD) Oncolytic Adenovirus: Replication and Immunotherapeutic Effects in Recurrent Malignant Glioma.

Lang FF, Conrad C, Gomez-Manzano C, Yung WKA, Sawaya R, Weinberg JS, Prabhu SS, Rao G, Fuller GN, Aldape KD, Gumin J, Vence LM, Wistuba I, Rodriguez-Canales J, Villalobos PA, Dirven CMF, Tejada S, Valle RD, Alonso MM, Ewald B, Peterkin JJ, Tufaro F, Fueyo J.

J Clin Oncol. 2018 May 10;36(14):1419-1427. doi: 10.1200/JCO.2017.75.8219. Epub 2018 Feb 12.

11.

Dexamethasone-mediated oncogenicity in vitro and in an animal model of glioblastoma.

Luedi MM, Singh SK, Mosley JC, Hassan ISA, Hatami M, Gumin J, Andereggen L, Sulman EP, Lang FF, Stueber F, Fuller GN, Colen RR, Zinn PO.

J Neurosurg. 2018 Dec 1;129(6):1446-1455. doi: 10.3171/2017.7.JNS17668.

PMID:
29328002
12.

Mesenchymal stem cells as natural biofactories for exosomes carrying miR-124a in the treatment of gliomas.

Lang FM, Hossain A, Gumin J, Momin EN, Shimizu Y, Ledbetter D, Shahar T, Yamashita S, Parker Kerrigan B, Fueyo J, Sawaya R, Lang FF.

Neuro Oncol. 2018 Feb 19;20(3):380-390. doi: 10.1093/neuonc/nox152.

13.

Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587.

Figueroa J, Phillips LM, Shahar T, Hossain A, Gumin J, Kim H, Bean AJ, Calin GA, Fueyo J, Walters ET, Kalluri R, Verhaak RG, Lang FF.

Cancer Res. 2017 Nov 1;77(21):5808-5819. doi: 10.1158/0008-5472.CAN-16-2524. Epub 2017 Aug 30.

14.

Efficacy of Onalespib, a Long-Acting Second-Generation HSP90 Inhibitor, as a Single Agent and in Combination with Temozolomide against Malignant Gliomas.

Canella A, Welker AM, Yoo JY, Xu J, Abas FS, Kesanakurti D, Nagarajan P, Beattie CE, Sulman EP, Liu J, Gumin J, Lang FF, Gurcan MN, Kaur B, Sampath D, Puduvalli VK.

Clin Cancer Res. 2017 Oct 15;23(20):6215-6226. doi: 10.1158/1078-0432.CCR-16-3151. Epub 2017 Jul 5.

15.

Percentage of mesenchymal stem cells in high-grade glioma tumor samples correlates with patient survival.

Shahar T, Rozovski U, Hess KR, Hossain A, Gumin J, Gao F, Fuller GN, Goodman L, Sulman EP, Lang FF.

Neuro Oncol. 2017 May 1;19(5):660-668. doi: 10.1093/neuonc/now239.

16.

Ionizing radiation augments glioma tropism of mesenchymal stem cells.

Thomas JG, Parker Kerrigan BC, Hossain A, Gumin J, Shinojima N, Nwajei F, Ezhilarasan R, Love P, Sulman EP, Lang FF.

J Neurosurg. 2018 Jan;128(1):287-295. doi: 10.3171/2016.9.JNS16278. Epub 2017 Mar 31.

17.

Preclinical Evaluation of Sequential Combination of Oncolytic Adenovirus Delta-24-RGD and Phosphatidylserine-Targeting Antibody in Pancreatic Ductal Adenocarcinoma.

Dai B, Roife D, Kang Y, Gumin J, Rios Perez MV, Li X, Pratt M, Brekken RA, Fueyo-Margareto J, Lang FF, Fleming JB.

Mol Cancer Ther. 2017 Apr;16(4):662-670. doi: 10.1158/1535-7163.MCT-16-0526. Epub 2017 Jan 30.

18.

TMEM43/LUMA is a key signaling component mediating EGFR-induced NF-κB activation and tumor progression.

Jiang C, Zhu Y, Zhou Z, Gumin J, Bengtsson L, Wu W, Songyang Z, Lang FF, Lin X.

Oncogene. 2017 May 18;36(20):2813-2823. doi: 10.1038/onc.2016.430. Epub 2016 Dec 19.

PMID:
27991920
19.

A Dexamethasone-regulated Gene Signature Is Prognostic for Poor Survival in Glioblastoma Patients.

Luedi MM, Singh SK, Mosley JC, Hatami M, Gumin J, Sulman EP, Lang FF, Stueber F, Zinn PO, Colen RR.

J Neurosurg Anesthesiol. 2017 Jan;29(1):46-58.

20.

Critical Role of Autophagy in the Processing of Adenovirus Capsid-Incorporated Cancer-Specific Antigens.

Klein SR, Jiang H, Hossain MB, Fan X, Gumin J, Dong A, Alonso MM, Gomez-Manzano C, Fueyo J.

PLoS One. 2016 Apr 19;11(4):e0153814. doi: 10.1371/journal.pone.0153814. eCollection 2016.

21.

Soluble Tie2 overrides the heightened invasion induced by anti-angiogenesis therapies in gliomas.

Cortes-Santiago N, Hossain MB, Gabrusiewicz K, Fan X, Gumin J, Marini FC, Alonso MM, Lang F, Yung WK, Fueyo J, Gomez-Manzano C.

Oncotarget. 2016 Mar 29;7(13):16146-57. doi: 10.18632/oncotarget.7550.

22.

Mir-21-Sox2 Axis Delineates Glioblastoma Subtypes with Prognostic Impact.

Sathyan P, Zinn PO, Marisetty AL, Liu B, Kamal MM, Singh SK, Bady P, Lu L, Wani KM, Veo BL, Gumin J, Kassem DH, Robinson F, Weng C, Baladandayuthapani V, Suki D, Colman H, Bhat KP, Sulman EP, Aldape K, Colen RR, Verhaak RG, Lu Z, Fuller GN, Huang S, Lang FF, Sawaya R, Hegi M, Majumder S.

J Neurosci. 2015 Nov 11;35(45):15097-112. doi: 10.1523/JNEUROSCI.1265-15.2015.

23.

Aberrant mesenchymal differentiation of glioma stem-like cells: implications for therapeutic targeting.

Balasubramaniyan V, Vaillant B, Wang S, Gumin J, Butalid ME, Sai K, Mukheef F, Kim SH, Boddeke HW, Lang F, Aldape K, Sulman EP, Bhat KP, Colman H.

Oncotarget. 2015 Oct 13;6(31):31007-17. doi: 10.18632/oncotarget.5219.

24.

Integrated Transcriptomic and Glycomic Profiling of Glioma Stem Cell Xenografts.

Wildburger NC, Zhou S, Zacharias LG, Kroes RA, Moskal JR, Schmidt M, Mirzaei P, Gumin J, Lang FF, Mechref Y, Nilsson CL.

J Proteome Res. 2015 Sep 4;14(9):3932-9. doi: 10.1021/acs.jproteome.5b00549. Epub 2015 Aug 4.

25.

Mesenchymal Stem Cells Isolated From Human Gliomas Increase Proliferation and Maintain Stemness of Glioma Stem Cells Through the IL-6/gp130/STAT3 Pathway.

Hossain A, Gumin J, Gao F, Figueroa J, Shinojima N, Takezaki T, Priebe W, Villarreal D, Kang SG, Joyce C, Sulman E, Wang Q, Marini FC, Andreeff M, Colman H, Lang FF.

Stem Cells. 2015 Aug;33(8):2400-15. doi: 10.1002/stem.2053. Epub 2015 May 27.

26.

ESI-MS/MS and MALDI-IMS Localization Reveal Alterations in Phosphatidic Acid, Diacylglycerol, and DHA in Glioma Stem Cell Xenografts.

Wildburger NC, Wood PL, Gumin J, Lichti CF, Emmett MR, Lang FF, Nilsson CL.

J Proteome Res. 2015 Jun 5;14(6):2511-9. doi: 10.1021/acs.jproteome.5b00076. Epub 2015 Apr 29.

27.

Orthotopic murine model of a primary malignant bone tumor in the spine: functional, bioluminescence, and histological correlations.

Fahim DK, Tatsui CE, Suki D, Gumin J, Lang FF, Rhines LD.

J Neurosurg Spine. 2014 Sep;21(3):378-85. doi: 10.3171/2014.5.SPINE13205. Epub 2014 Jun 27.

PMID:
24971476
28.

Delta-24-RGD oncolytic adenovirus elicits anti-glioma immunity in an immunocompetent mouse model.

Jiang H, Clise-Dwyer K, Ruisaard KE, Fan X, Tian W, Gumin J, Lamfers ML, Kleijn A, Lang FF, Yung WK, Vence LM, Gomez-Manzano C, Fueyo J.

PLoS One. 2014 May 14;9(5):e97407. doi: 10.1371/journal.pone.0097407. eCollection 2014.

29.

Two mature products of MIR-491 coordinate to suppress key cancer hallmarks in glioblastoma.

Li X, Liu Y, Granberg KJ, Wang Q, Moore LM, Ji P, Gumin J, Sulman EP, Calin GA, Haapasalo H, Nykter M, Shmulevich I, Fuller GN, Lang FF, Zhang W.

Oncogene. 2015 Mar 26;34(13):1619-1628. doi: 10.1038/onc.2014.98. Epub 2014 Apr 21.

30.

Mesenchymal differentiation mediated by NF-κB promotes radiation resistance in glioblastoma.

Bhat KPL, Balasubramaniyan V, Vaillant B, Ezhilarasan R, Hummelink K, Hollingsworth F, Wani K, Heathcock L, James JD, Goodman LD, Conroy S, Long L, Lelic N, Wang S, Gumin J, Raj D, Kodama Y, Raghunathan A, Olar A, Joshi K, Pelloski CE, Heimberger A, Kim SH, Cahill DP, Rao G, Den Dunnen WFA, Boddeke HWGM, Phillips HS, Nakano I, Lang FF, Colman H, Sulman EP, Aldape K.

Cancer Cell. 2013 Sep 9;24(3):331-46. doi: 10.1016/j.ccr.2013.08.001. Epub 2013 Aug 29.

31.

TGF-β mediates homing of bone marrow-derived human mesenchymal stem cells to glioma stem cells.

Shinojima N, Hossain A, Takezaki T, Fueyo J, Gumin J, Gao F, Nwajei F, Marini FC, Andreeff M, Kuratsu J, Lang FF.

Cancer Res. 2013 Apr 1;73(7):2333-44. doi: 10.1158/0008-5472.CAN-12-3086. Epub 2013 Jan 30.

32.

The tumorigenic FGFR3-TACC3 gene fusion escapes miR-99a regulation in glioblastoma.

Parker BC, Annala MJ, Cogdell DE, Granberg KJ, Sun Y, Ji P, Li X, Gumin J, Zheng H, Hu L, Yli-Harja O, Haapasalo H, Visakorpi T, Liu X, Liu CG, Sawaya R, Fuller GN, Chen K, Lang FF, Nykter M, Zhang W.

J Clin Invest. 2013 Feb;123(2):855-65. doi: 10.1172/JCI67144. Epub 2013 Jan 9.

33.

REST regulates oncogenic properties of glioblastoma stem cells.

Kamal MM, Sathyan P, Singh SK, Zinn PO, Marisetty AL, Liang S, Gumin J, El-Mesallamy HO, Suki D, Colman H, Fuller GN, Lang FF, Majumder S.

Stem Cells. 2012 Mar;30(3):405-14. doi: 10.1002/stem.1020. Erratum in: Stem Cells. 2012 May;30(5):1049.

34.

The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma.

Bhat KP, Salazar KL, Balasubramaniyan V, Wani K, Heathcock L, Hollingsworth F, James JD, Gumin J, Diefes KL, Kim SH, Turski A, Azodi Y, Yang Y, Doucette T, Colman H, Sulman EP, Lang FF, Rao G, Copray S, Vaillant BD, Aldape KD.

Genes Dev. 2011 Dec 15;25(24):2594-609. doi: 10.1101/gad.176800.111.

35.

Mesenchymal stem cells display tumor-specific tropism in an RCAS/Ntv-a glioma model.

Doucette T, Rao G, Yang Y, Gumin J, Shinojima N, Bekele BN, Qiao W, Zhang W, Lang FF.

Neoplasia. 2011 Aug;13(8):716-25.

36.

Isolation and perivascular localization of mesenchymal stem cells from mouse brain.

Kang SG, Shinojima N, Hossain A, Gumin J, Yong RL, Colman H, Marini F, Andreeff M, Lang FF.

Neurosurgery. 2010 Sep;67(3):711-20. doi: 10.1227/01.NEU.0000377859.06219.78.

37.

Glioma-associated cancer-initiating cells induce immunosuppression.

Wei J, Barr J, Kong LY, Wang Y, Wu A, Sharma AK, Gumin J, Henry V, Colman H, Sawaya R, Lang FF, Heimberger AB.

Clin Cancer Res. 2010 Jan 15;16(2):461-73. doi: 10.1158/1078-0432.CCR-09-1983. Epub 2010 Jan 12. Retraction in: Clin Cancer Res. 2015 May 1;21(9):2189.

38.

Glioblastoma cancer-initiating cells inhibit T-cell proliferation and effector responses by the signal transducers and activators of transcription 3 pathway.

Wei J, Barr J, Kong LY, Wang Y, Wu A, Sharma AK, Gumin J, Henry V, Colman H, Priebe W, Sawaya R, Lang FF, Heimberger AB.

Mol Cancer Ther. 2010 Jan;9(1):67-78. doi: 10.1158/1535-7163.MCT-09-0734. Epub 2010 Jan 6.

39.

Platelet-derived growth factor BB mediates the tropism of human mesenchymal stem cells for malignant gliomas.

Hata N, Shinojima N, Gumin J, Yong R, Marini F, Andreeff M, Lang FF.

Neurosurgery. 2010 Jan;66(1):144-56; discussion 156-7. doi: 10.1227/01.NEU.0000363149.58885.2E.

40.

Human bone marrow-derived mesenchymal stem cells for intravascular delivery of oncolytic adenovirus Delta24-RGD to human gliomas.

Yong RL, Shinojima N, Fueyo J, Gumin J, Vecil GG, Marini FC, Bogler O, Andreeff M, Lang FF.

Cancer Res. 2009 Dec 1;69(23):8932-40. doi: 10.1158/0008-5472.CAN-08-3873. Epub 2009 Nov 17.

41.

An orthotopic murine model of human spinal metastasis: histological and functional correlations.

Tatsui CE, Lang FF, Gumin J, Suki D, Shinojima N, Rhines LD.

J Neurosurg Spine. 2009 Jun;10(6):501-12. doi: 10.3171/2009.2.SPINE08391.

42.

Tie2-mediated multidrug resistance in malignant gliomas is associated with upregulation of ABC transporters.

Martin V, Xu J, Pabbisetty SK, Alonso MM, Liu D, Lee OH, Gumin J, Bhat KP, Colman H, Lang FF, Fueyo J, Gomez-Manzano C.

Oncogene. 2009 Jun 18;28(24):2358-63. doi: 10.1038/onc.2009.103. Epub 2009 May 4.

43.

Simultaneous phosphorylation of p53 at serine 15 and 20 induces apoptosis in human glioma cells by increasing expression of pro-apoptotic genes.

Amano T, Nakamizo A, Mishra SK, Gumin J, Shinojima N, Sawaya R, Lang FF.

J Neurooncol. 2009 May;92(3):357-71. doi: 10.1007/s11060-009-9844-1. Epub 2009 Apr 9.

PMID:
19357962
44.

Human bone marrow-derived mesenchymal stem cells in the treatment of gliomas.

Nakamizo A, Marini F, Amano T, Khan A, Studeny M, Gumin J, Chen J, Hentschel S, Vecil G, Dembinski J, Andreeff M, Lang FF.

Cancer Res. 2005 Apr 15;65(8):3307-18. Erratum in: Cancer Res. 2006 Jun 1;66(11):5975.

45.

PAX6 suppresses growth of human glioblastoma cells.

Zhou YH, Wu X, Tan F, Shi YX, Glass T, Liu TJ, Wathen K, Hess KR, Gumin J, Lang F, Yung WK.

J Neurooncol. 2005 Feb;71(3):223-9.

PMID:
15735909
46.

Mechanisms of action of rapamycin in gliomas.

Heimberger AB, Wang E, McGary EC, Hess KR, Henry VK, Shono T, Cohen Z, Gumin J, Sawaya R, Conrad CA, Lang FF.

Neuro Oncol. 2005 Jan;7(1):1-11.

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