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Items: 44


RNAi as a Tool to Study Virulence in the Pathogenic Yeast Candida glabrata.

Ishchuk OP, Ahmad KM, Koruza K, Bojanovič K, Sprenger M, Kasper L, Brunke S, Hube B, Säll T, Hellmark T, Gullstrand B, Brion C, Freel K, Schacherer J, Regenberg B, Knecht W, Piškur J.

Front Microbiol. 2019 Jul 24;10:1679. doi: 10.3389/fmicb.2019.01679. eCollection 2019.


Low plasma concentrations of apolipoprotein M are associated with disease activity and endothelial dysfunction in systemic lupus erythematosus.

Tydén H, Lood C, Jönsen A, Gullstrand B, Kahn R, Linge P, Kumaraswamy SB, Dahlbäck B, Bengtsson AA.

Arthritis Res Ther. 2019 May 2;21(1):110. doi: 10.1186/s13075-019-1890-2.


Cardiovascular disease in systemic lupus erythematosus is associated with increased levels of biomarkers reflecting receptor-activated apoptosis.

Wigren M, Svenungsson E, Mattisson IY, Gustafsson JT, Gunnarsson I, Zickert A, Elvin K, Jensen-Urstad K, Bengtsson A, Gullstrand B, Fredrikson GN, Nilsson J.

Atherosclerosis. 2018 Mar;270:1-7. doi: 10.1016/j.atherosclerosis.2018.01.022. Epub 2018 Jan 17.


Stress-induced release of the S100A8/A9 alarmin is elevated in coronary artery disease patients with impaired cortisol response.

Jonasson L, Grauen Larsen H, Lundberg AK, Gullstrand B, Bengtsson AA, Schiopu A.

Sci Rep. 2017 Dec 13;7(1):17545. doi: 10.1038/s41598-017-17586-6.


Plasma C4d as marker for lupus nephritis in systemic lupus erythematosus.

Martin M, Smoląg KI, Björk A, Gullstrand B, Okrój M, Leffler J, Jönsen A, Bengtsson AA, Blom AM.

Arthritis Res Ther. 2017 Dec 6;19(1):266. doi: 10.1186/s13075-017-1470-2.


Endothelial dysfunction is associated with activation of the type I interferon system and platelets in patients with systemic lupus erythematosus.

Tydén H, Lood C, Gullstrand B, Nielsen CT, Heegaard NHH, Kahn R, Jönsen A, Bengtsson AA.

RMD Open. 2017 Oct 25;3(2):e000508. doi: 10.1136/rmdopen-2017-000508. eCollection 2017.


A single nucleotide polymorphism in the NCF1 gene leading to reduced oxidative burst is associated with systemic lupus erythematosus.

Olsson LM, Johansson ÅC, Gullstrand B, Jönsen A, Saevarsdottir S, Rönnblom L, Leonard D, Wetterö J, Sjöwall C, Svenungsson E, Gunnarsson I, Bengtsson AA, Holmdahl R.

Ann Rheum Dis. 2017 Sep;76(9):1607-1613. doi: 10.1136/annrheumdis-2017-211287. Epub 2017 Jun 12.


Tumour necrosis factor-α/etanercept complexes in serum predict long-term efficacy of etanercept treatment in seronegative rheumatoid arthritis.

Berthold E, Månsson B, Gullstrand B, Geborek P, Saxne T, Bengtsson AA, Kahn R.

Scand J Rheumatol. 2018 Jan;47(1):22-26. doi: 10.1080/03009742.2017.1290822. Epub 2017 May 9.


Decreased platelet size is associated with platelet activation and anti-phospholipid syndrome in systemic lupus erythematosus.

Lood C, Tydén H, Gullstrand B, Nielsen CT, Heegaard NH, Linge P, Jönsen A, Hesselstrand R, Kahn R, Bengtsson AA.

Rheumatology (Oxford). 2017 Mar 1;56(3):408-416. doi: 10.1093/rheumatology/kew437.


Deciphering systemic lupus erythematosus-associated serum biomarkers reflecting apoptosis and disease activity.

Delfani P, Sturfelt G, Gullstrand B, Carlsson A, Kassandra M, Borrebaeck CA, Bengtsson AA, Wingren C.

Lupus. 2017 Apr;26(4):373-387. doi: 10.1177/0961203316669240. Epub 2016 Sep 30.


Pro-inflammatory S100 proteins are associated with glomerulonephritis and anti-dsDNA antibodies in systemic lupus erythematosus.

Tydén H, Lood C, Gullstrand B, Jönsen A, Ivars F, Leanderson T, Bengtsson AA.

Lupus. 2017 Feb;26(2):139-149. doi: 10.1177/0961203316655208. Epub 2016 Jul 19.


IRF7 inhibition prevents destructive innate immunity-A target for nonantibiotic therapy of bacterial infections.

Puthia M, Ambite I, Cafaro C, Butler D, Huang Y, Lutay N, Rydström G, Gullstrand B, Swaminathan B, Nadeem A, Nilsson B, Svanborg C.

Sci Transl Med. 2016 Apr 27;8(336):336ra59. doi: 10.1126/scitranslmed.aaf1156.


Platelet-Derived S100A8/A9 and Cardiovascular Disease in Systemic Lupus Erythematosus.

Lood C, Tydén H, Gullstrand B, Jönsen A, Källberg E, Mörgelin M, Kahn R, Gunnarsson I, Leanderson T, Ivars F, Svenungsson E, Bengtsson AA.

Arthritis Rheumatol. 2016 Aug;68(8):1970-80. doi: 10.1002/art.39656.


The assessment of serum-mediated phagocytosis of necrotic material by polymorphonuclear leukocytes to diagnose and predict the clinical features of systemic lupus erythematosus: an observational longitudinal study.

Compagno M, Gullstrand B, Jacobsen S, Eilertsen GØ, Nilsson JÅ, Lood C, Jönsen A, Truedsson L, Sturfelt G, Bengtsson AA.

Arthritis Res Ther. 2016 Feb 10;18:44. doi: 10.1186/s13075-016-0941-1.


Circulating complexes between tumour necrosis factor-alpha and etanercept predict long-term efficacy of etanercept in juvenile idiopathic arthritis.

Kahn R, Berthold E, Gullstrand B, Schmidt T, Kahn F, Geborek P, Saxne T, Bengtsson AA, Månsson B.

Acta Paediatr. 2016 Apr;105(4):427-32. doi: 10.1111/apa.13319. Epub 2016 Feb 1.


A subset of patients with systemic lupus erythematosus fails to degrade DNA from multiple clinically relevant sources.

Leffler J, Ciacma K, Gullstrand B, Bengtsson AA, Martin M, Blom AM.

Arthritis Res Ther. 2015 Aug 13;17:205. doi: 10.1186/s13075-015-0726-y.


Type I interferon-mediated skewing of the serotonin synthesis is associated with severe disease in systemic lupus erythematosus.

Lood C, Tydén H, Gullstrand B, Klint C, Wenglén C, Nielsen CT, Heegaard NH, Jönsen A, Kahn R, Bengtsson AA.

PLoS One. 2015 Apr 21;10(4):e0125109. doi: 10.1371/journal.pone.0125109. eCollection 2015.


Platelet activation and anti-phospholipid antibodies collaborate in the activation of the complement system on platelets in systemic lupus erythematosus.

Lood C, Tydén H, Gullstrand B, Sturfelt G, Jönsen A, Truedsson L, Bengtsson AA.

PLoS One. 2014 Jun 12;9(6):e99386. doi: 10.1371/journal.pone.0099386. eCollection 2014.


Low production of reactive oxygen species in granulocytes is associated with organ damage in systemic lupus erythematosus.

Bengtsson AA, Pettersson Å, Wichert S, Gullstrand B, Hansson M, Hellmark T, Johansson ÅC.

Arthritis Res Ther. 2014 Jun 5;16(3):R120. doi: 10.1186/ar4575.


Serum from patients with systemic vasculitis induces alternatively activated macrophage M2c polarization.

Ohlsson SM, Linge CP, Gullstrand B, Lood C, Johansson A, Ohlsson S, Lundqvist A, Bengtsson AA, Carlsson F, Hellmark T.

Clin Immunol. 2014 May-Jun;152(1-2):10-9. doi: 10.1016/j.clim.2014.02.016. Epub 2014 Mar 12.


A candidate gene approach to ANCA-associated vasculitis reveals links to the C3 and CTLA-4 genes but not to the IL1-Ra and Fcγ-RIIa genes.

Persson U, Gullstrand B, Pettersson A, Sturfelt G, Truedsson L, Segelmark M.

Kidney Blood Press Res. 2013;37(6):641-8. doi: 10.1159/000355744. Epub 2013 Dec 14.


Degradation of neutrophil extracellular traps co-varies with disease activity in patients with systemic lupus erythematosus.

Leffler J, Gullstrand B, Jönsen A, Nilsson JÅ, Martin M, Blom AM, Bengtsson AA.

Arthritis Res Ther. 2013 Aug 14;15(4):R84. doi: 10.1186/ar4264.


Increased serum levels of S100A8/A9 and S100A12 are associated with cardiovascular disease in patients with inactive systemic lupus erythematosus.

Tydén H, Lood C, Gullstrand B, Jönsen A, Nived O, Sturfelt G, Truedsson L, Ivars F, Leanderson T, Bengtsson AA.

Rheumatology (Oxford). 2013 Nov;52(11):2048-55. doi: 10.1093/rheumatology/ket263. Epub 2013 Aug 13.


Increased C1q, C4 and C3 deposition on platelets in patients with systemic lupus erythematosus--a possible link to venous thrombosis?

Lood C, Eriksson S, Gullstrand B, Jönsen A, Sturfelt G, Truedsson L, Bengtsson AA.

Lupus. 2012 Nov;21(13):1423-32. doi: 10.1177/0961203312457210. Epub 2012 Aug 9.


Vaccination against encapsulated bacteria in hereditary C2 deficiency results in antibody response and opsonization due to antibody-dependent complement activation.

Jönsson G, Lood C, Gullstrand B, Holmström E, Selander B, Braconier JH, Sturfelt G, Bengtsson AA, Truedsson L.

Clin Immunol. 2012 Sep;144(3):214-27. doi: 10.1016/j.clim.2012.06.008. Epub 2012 Jul 6.


Combination of autoantibodies against different histone proteins influences complement-dependent phagocytosis of necrotic cell material by polymorphonuclear leukocytes in systemic lupus erythematosus.

Gullstrand B, Lefort MH, Tydén H, Jönsen A, Lood C, Johansson A, Jacobsen S, Truedsson L, Bengtsson AA.

J Rheumatol. 2012 Aug;39(8):1619-27. doi: 10.3899/jrheum.111511. Epub 2012 Jul 1.


IgG glycan hydrolysis by endoglycosidase S diminishes the proinflammatory properties of immune complexes from patients with systemic lupus erythematosus: a possible new treatment?

Lood C, Allhorn M, Lood R, Gullstrand B, Olin AI, Rönnblom L, Truedsson L, Collin M, Bengtsson AA.

Arthritis Rheum. 2012 Aug;64(8):2698-706. doi: 10.1002/art.34454.


Neutrophil extracellular traps that are not degraded in systemic lupus erythematosus activate complement exacerbating the disease.

Leffler J, Martin M, Gullstrand B, Tydén H, Lood C, Truedsson L, Bengtsson AA, Blom AM.

J Immunol. 2012 Apr 1;188(7):3522-31. doi: 10.4049/jimmunol.1102404. Epub 2012 Feb 17.


Increased IgG on cell-derived plasma microparticles in systemic lupus erythematosus is associated with autoantibodies and complement activation.

Nielsen CT, Østergaard O, Stener L, Iversen LV, Truedsson L, Gullstrand B, Jacobsen S, Heegaard NH.

Arthritis Rheum. 2012 Apr;64(4):1227-36. doi: 10.1002/art.34381. Epub 2012 Jan 11.


Protein synthesis of the pro-inflammatory S100A8/A9 complex in plasmacytoid dendritic cells and cell surface S100A8/A9 on leukocyte subpopulations in systemic lupus erythematosus.

Lood C, Stenström M, Tydén H, Gullstrand B, Källberg E, Leanderson T, Truedsson L, Sturfelt G, Ivars F, Bengtsson AA.

Arthritis Res Ther. 2011 Apr 14;13(2):R60. doi: 10.1186/ar3314.


Recombinant human complement component C2 produced in a human cell line restores the classical complement pathway activity in-vitro: an alternative treatment for C2 deficiency diseases.

Martini PG, Cook LC, Alderucci S, Norton AW, Lundberg DM, Fish SM, Langsetmo K, Jönsson G, Lood C, Gullstrand B, Zaleski KJ, Savioli N, Lottherand J, Bedard C, Gill J, Concino MF, Heartlein MW, Truedsson L, Powell JL, Tzianabos AO.

BMC Immunol. 2010 Aug 20;11:43. doi: 10.1186/1471-2172-11-43.


Homozygosity for a novel mutation in the C1q C chain gene in a Turkish family with hereditary C1q deficiency.

Gulez N, Genel F, Atlihan F, Gullstrand B, Skattum L, Schejbel L, Garred P, Truedsson L.

J Investig Allergol Clin Immunol. 2010;20(3):255-8.


Platelet transcriptional profile and protein expression in patients with systemic lupus erythematosus: up-regulation of the type I interferon system is strongly associated with vascular disease.

Lood C, Amisten S, Gullstrand B, Jönsen A, Allhorn M, Truedsson L, Sturfelt G, Erlinge D, Bengtsson AA.

Blood. 2010 Sep 16;116(11):1951-7. doi: 10.1182/blood-2010-03-274605. Epub 2010 Jun 10.


C1q inhibits immune complex-induced interferon-alpha production in plasmacytoid dendritic cells: a novel link between C1q deficiency and systemic lupus erythematosus pathogenesis.

Lood C, Gullstrand B, Truedsson L, Olin AI, Alm GV, Rönnblom L, Sturfelt G, Eloranta ML, Bengtsson AA.

Arthritis Rheum. 2009 Oct;60(10):3081-90. doi: 10.1002/art.24852.


Complement classical pathway components are all important in clearance of apoptotic and secondary necrotic cells.

Gullstrand B, Mårtensson U, Sturfelt G, Bengtsson AA, Truedsson L.

Clin Exp Immunol. 2009 May;156(2):303-11. doi: 10.1111/j.1365-2249.2009.03896.x. Epub 2009 Mar 2.


Serum bactericidal activity against Neisseria meningitidis in patients with C3 nephritic factors is dependent on IgG allotypes.

Skattum L, Gullstrand B, Holmström E, Oxelius VA, Truedsson L.

Clin Immunol. 2008 Oct;129(1):123-31. doi: 10.1016/j.clim.2008.06.010. Epub 2008 Jul 29.


SLE serum induces classical caspase-dependent apoptosis independent of death receptors.

Bengtsson AA, Gullstrand B, Truedsson L, Sturfelt G.

Clin Immunol. 2008 Jan;126(1):57-66. Epub 2007 Nov 26.


Association between SLE nephritis and polymorphic variants of the CRP and FcgammaRIIIa genes.

Jönsen A, Gunnarsson I, Gullstrand B, Svenungsson E, Bengtsson AA, Nived O, Lundberg IE, Truedsson L, Sturfelt G.

Rheumatology (Oxford). 2007 Sep;46(9):1417-21. Epub 2007 Jun 27.


Characterization of non-expressed C4 genes in a case of complete C4 deficiency: identification of a novel point mutation leading to a premature stop codon.

Fredrikson GN, Gullstrand B, Schneider PM, Witzel-Schlömp K, Sjöholm AG, Alper CA, Awdeh Z, Truedsson L.

Hum Immunol. 1998 Nov;59(11):713-9.


Expression of properdin in complete and incomplete deficiency: normal in vitro synthesis by monocytes in two cases with properdin deficiency type II due to distinct mutations.

Fredrikson GN, Gullstrand B, Westberg J, Sjöholm AG, Uhlén M, Truedsson L.

J Clin Immunol. 1998 Jul;18(4):272-82.


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