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Items: 1 to 50 of 119

1.

Sequence variation at the MTHFD1L-AKAP12 and FOPNL loci does not influence multiple myeloma survival in Sweden.

Ali M, Lemonakis K, Wihlborg AK, Veskovski L, Turesson I, Mellqvist UH, Gullberg U, Hansson M, Nilsson B.

Blood Cancer J. 2019 Jul 30;9(8):57. doi: 10.1038/s41408-019-0222-8. No abstract available.

2.

Author Correction: Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma.

Went M, Sud A, Försti A, Halvarsson BM, Weinhold N, Kimber S, van Duin M, Thorleifsson G, Holroyd A, Johnson DC, Li N, Orlando G, Law PJ, Ali M, Chen B, Mitchell JS, Gudbjartsson DF, Kuiper R, Stephens OW, Bertsch U, Broderick P, Campo C, Bandapalli OR, Einsele H, Gregory WA, Gullberg U, Hillengass J, Hoffmann P, Jackson GH, Jöckel KH, Johnsson E, Kristinsson SY, Mellqvist UH, Nahi H, Easton D, Pharoah P, Dunning A, Peto J, Canzian F, Swerdlow A, Eeles RA, Kote-Jarai Z, Muir K, Pashayan N; PRACTICAL consortium, Nickel J, Nöthen MM, Rafnar T, Ross FM, da Silva Filho MI, Thomsen H, Turesson I, Vangsted A, Andersen NF, Waage A, Walker BA, Wihlborg AK, Broyl A, Davies FE, Thorsteinsdottir U, Langer C, Hansson M, Goldschmidt H, Kaiser M, Sonneveld P, Stefansson K, Morgan GJ, Hemminki K, Nilsson B, Houlston RS.

Nat Commun. 2019 Jan 10;10(1):213. doi: 10.1038/s41467-018-08107-8.

3.

Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma.

Went M, Sud A, Försti A, Halvarsson BM, Weinhold N, Kimber S, van Duin M, Thorleifsson G, Holroyd A, Johnson DC, Li N, Orlando G, Law PJ, Ali M, Chen B, Mitchell JS, Gudbjartsson DF, Kuiper R, Stephens OW, Bertsch U, Broderick P, Campo C, Bandapalli OR, Einsele H, Gregory WA, Gullberg U, Hillengass J, Hoffmann P, Jackson GH, Jöckel KH, Johnsson E, Kristinsson SY, Mellqvist UH, Nahi H, Easton D, Pharoah P, Dunning A, Peto J, Canzian F, Swerdlow A, Eeles RA, Kote-Jarai Z, Muir K, Pashayan N, Nickel J, Nöthen MM, Rafnar T, Ross FM, da Silva Filho MI, Thomsen H, Turesson I, Vangsted A, Andersen NF, Waage A, Walker BA, Wihlborg AK, Broyl A, Davies FE, Thorsteinsdottir U, Langer C, Hansson M, Goldschmidt H, Kaiser M, Sonneveld P, Stefansson K, Morgan GJ, Hemminki K, Nilsson B, Houlston RS; PRACTICAL consortium.

Nat Commun. 2018 Sep 13;9(1):3707. doi: 10.1038/s41467-018-04989-w. Erratum in: Nat Commun. 2019 Jan 10;10(1):213.

4.

The multiple myeloma risk allele at 5q15 lowers ELL2 expression and increases ribosomal gene expression.

Ali M, Ajore R, Wihlborg AK, Niroula A, Swaminathan B, Johnsson E, Stephens OW, Morgan G, Meissner T, Turesson I, Goldschmidt H, Mellqvist UH, Gullberg U, Hansson M, Hemminki K, Nahi H, Waage A, Weinhold N, Nilsson B.

Nat Commun. 2018 Apr 25;9(1):1649. doi: 10.1038/s41467-018-04082-2.

5.

Direct evidence for a polygenic etiology in familial multiple myeloma.

Halvarsson BM, Wihlborg AK, Ali M, Lemonakis K, Johnsson E, Niroula A, Cibulskis C, Weinhold N, Försti A, Alici E, Langer C, Pfreundschuh M, Goldschmidt H, Mellqvist UH, Turesson I, Waage A, Hemminki K, Golub T, Nahi H, Gullberg U, Hansson M, Nilsson B.

Blood Adv. 2017 Apr 7;1(10):619-623. doi: 10.1182/bloodadvances.2016003111. eCollection 2017 Apr 11.

6.

DNA and RNA binding by the Wilms' tumour gene 1 (WT1) protein +KTS and -KTS isoforms-From initial observations to recent global genomic analyses.

Ullmark T, Montano G, Gullberg U.

Eur J Haematol. 2018 Mar;100(3):229-240. doi: 10.1111/ejh.13010. Epub 2018 Jan 10. Review.

PMID:
29240258
7.

The transcriptional coregulator NAB2 is a target gene for the Wilms' tumor gene 1 protein (WT1) in leukemic cells.

Nilsson HJ, Montano G, Ullmark T, Lennartsson A, Drott K, Järvstråt L, Nilsson B, Vidovic K, Gullberg U.

Oncotarget. 2017 Aug 3;8(50):87136-87150. doi: 10.18632/oncotarget.19896. eCollection 2017 Oct 20.

8.

Identification of sequence variants influencing immunoglobulin levels.

Jonsson S, Sveinbjornsson G, de Lapuente Portilla AL, Swaminathan B, Plomp R, Dekkers G, Ajore R, Ali M, Bentlage AEH, Elmér E, Eyjolfsson GI, Gudjonsson SA, Gullberg U, Gylfason A, Halldorsson BV, Hansson M, Holm H, Johansson Å, Johnsson E, Jonasdottir A, Ludviksson BR, Oddsson A, Olafsson I, Olafsson S, Sigurdardottir O, Sigurdsson A, Stefansdottir L, Masson G, Sulem P, Wuhrer M, Wihlborg AK, Thorleifsson G, Gudbjartsson DF, Thorsteinsdottir U, Vidarsson G, Jonsdottir I, Nilsson B, Stefansson K.

Nat Genet. 2017 Aug;49(8):1182-1191. doi: 10.1038/ng.3897. Epub 2017 Jun 19.

PMID:
28628107
9.

The HDAC inhibitor valproate induces a bivalent status of the CD20 promoter in CLL patients suggesting distinct epigenetic regulation of CD20 expression in CLL in vivo.

Scialdone A, Hasni MS, Damm JK, Lennartsson A, Gullberg U, Drott K.

Oncotarget. 2017 Jun 6;8(23):37409-37422. doi: 10.18632/oncotarget.16964.

10.

Anti-apoptotic quinolinate phosphoribosyltransferase (QPRT) is a target gene of Wilms' tumor gene 1 (WT1) protein in leukemic cells.

Ullmark T, Montano G, Järvstråt L, Jernmark Nilsson H, Håkansson E, Drott K, Nilsson B, Vidovic K, Gullberg U.

Biochem Biophys Res Commun. 2017 Jan 22;482(4):802-807. doi: 10.1016/j.bbrc.2016.11.114. Epub 2016 Nov 23.

PMID:
27889611
11.

Distinct global binding patterns of the Wilms tumor gene 1 (WT1) -KTS and +KTS isoforms in leukemic cells.

Ullmark T, Järvstråt L, Sandén C, Montano G, Jernmark-Nilsson H, Lilljebjörn H, Lennartsson A, Fioretos T, Drott K, Vidovic K, Nilsson B, Gullberg U.

Haematologica. 2017 Feb;102(2):336-345. doi: 10.3324/haematol.2016.149815. Epub 2016 Sep 9.

12.

Genome-wide association study identifies multiple susceptibility loci for multiple myeloma.

Mitchell JS, Li N, Weinhold N, Försti A, Ali M, van Duin M, Thorleifsson G, Johnson DC, Chen B, Halvarsson BM, Gudbjartsson DF, Kuiper R, Stephens OW, Bertsch U, Broderick P, Campo C, Einsele H, Gregory WA, Gullberg U, Henrion M, Hillengass J, Hoffmann P, Jackson GH, Johnsson E, Jöud M, Kristinsson SY, Lenhoff S, Lenive O, Mellqvist UH, Migliorini G, Nahi H, Nelander S, Nickel J, Nöthen MM, Rafnar T, Ross FM, da Silva Filho MI, Swaminathan B, Thomsen H, Turesson I, Vangsted A, Vogel U, Waage A, Walker BA, Wihlborg AK, Broyl A, Davies FE, Thorsteinsdottir U, Langer C, Hansson M, Kaiser M, Sonneveld P, Stefansson K, Morgan GJ, Goldschmidt H, Hemminki K, Nilsson B, Houlston RS.

Nat Commun. 2016 Jul 1;7:12050. doi: 10.1038/ncomms12050.

13.

The hematopoietic tumor suppressor interferon regulatory factor 8 (IRF8) is upregulated by the antimetabolite cytarabine in leukemic cells involving the zinc finger protein ZNF224, acting as a cofactor of the Wilms' tumor gene 1 (WT1) protein.

Montano G, Ullmark T, Jernmark-Nilsson H, Sodaro G, Drott K, Costanzo P, Vidovic K, Gullberg U.

Leuk Res. 2016 Jan;40:60-7. doi: 10.1016/j.leukres.2015.10.014. Epub 2015 Nov 2.

PMID:
26563595
14.

WT1-mediated repression of the proapoptotic transcription factor ZNF224 is triggered by the BCR-ABL oncogene.

Montano G, Vidovic K, Palladino C, Cesaro E, Sodaro G, Quintarelli C, De Angelis B, Errichiello S, Pane F, Izzo P, Grosso M, Gullberg U, Costanzo P.

Oncotarget. 2015 Sep 29;6(29):28223-37. doi: 10.18632/oncotarget.4950.

15.

Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma.

Swaminathan B, Thorleifsson G, Jöud M, Ali M, Johnsson E, Ajore R, Sulem P, Halvarsson BM, Eyjolfsson G, Haraldsdottir V, Hultman C, Ingelsson E, Kristinsson SY, Kähler AK, Lenhoff S, Masson G, Mellqvist UH, Månsson R, Nelander S, Olafsson I, Sigurðardottir O, Steingrimsdóttir H, Vangsted A, Vogel U, Waage A, Nahi H, Gudbjartsson DF, Rafnar T, Turesson I, Gullberg U, Stefánsson K, Hansson M, Thorsteinsdóttir U, Nilsson B.

Nat Commun. 2015 May 26;6:7213. doi: 10.1038/ncomms8213.

16.

Myeloid translocation gene-16 co-repressor promotes degradation of hypoxia-inducible factor 1.

Kumar P, Gullberg U, Olsson I, Ajore R.

PLoS One. 2015 May 14;10(5):e0123725. doi: 10.1371/journal.pone.0123725. eCollection 2015.

17.

Pharmacologically relevant doses of valproate upregulate CD20 expression in three diffuse large B-cell lymphoma patients in vivo.

Damm JK, Gordon S, Ehinger M, Jerkeman M, Gullberg U, Hultquist A, Drott K.

Exp Hematol Oncol. 2015 Jan 26;4:4. doi: 10.1186/2162-3619-4-4. eCollection 2015.

18.

The DEK oncoprotein and its emerging roles in gene regulation.

Sandén C, Gullberg U.

Leukemia. 2015 Aug;29(8):1632-6. doi: 10.1038/leu.2015.72. Epub 2015 Mar 13. Review.

PMID:
25765544
19.

The DEK oncoprotein is upregulated by multiple leukemia-associated fusion genes.

Sandén C, Nilsson HJ, Gullberg U.

Blood Cells Mol Dis. 2015 Mar;54(3):284-5. doi: 10.1016/j.bcmd.2014.11.014. Epub 2014 Nov 25. No abstract available.

PMID:
25524609
20.

The DEK oncoprotein binds to highly and ubiquitously expressed genes with a dual role in their transcriptional regulation.

Sandén C, Järvstråt L, Lennartsson A, Brattås PL, Nilsson B, Gullberg U.

Mol Cancer. 2014 Sep 12;13:215. doi: 10.1186/1476-4598-13-215.

21.

Robust isolation of malignant plasma cells in multiple myeloma.

Frigyesi I, Adolfsson J, Ali M, Christophersen MK, Johnsson E, Turesson I, Gullberg U, Hansson M, Nilsson B.

Blood. 2014 Feb 27;123(9):1336-40. doi: 10.1182/blood-2013-09-529800. Epub 2014 Jan 2.

22.

Forced expression of the DEK-NUP214 fusion protein promotes proliferation dependent on upregulation of mTOR.

Sandén C, Ageberg M, Petersson J, Lennartsson A, Gullberg U.

BMC Cancer. 2013 Sep 27;13:440. doi: 10.1186/1471-2407-13-440.

23.

Leukemia associated mutant Wilms' tumor gene 1 protein promotes expansion of human hematopoietic progenitor cells.

Vidovic K, Ullmark T, Rosberg B, Lennartsson A, Olofsson T, Nilsson B, Gullberg U.

Leuk Res. 2013 Oct;37(10):1341-9. doi: 10.1016/j.leukres.2013.06.018. Epub 2013 Jul 19.

PMID:
23871158
24.

The transcriptional co-repressor myeloid translocation gene 16 inhibits glycolysis and stimulates mitochondrial respiration.

Kumar P, Sharoyko VV, Spégel P, Gullberg U, Mulder H, Olsson I, Ajore R.

PLoS One. 2013 Jul 1;8(7):e68502. doi: 10.1371/journal.pone.0068502. Print 2013.

25.

Lentivirus-induced dendritic cells for immunization against high-risk WT1(+) acute myeloid leukemia.

Sundarasetty BS, Singh VK, Salguero G, Geffers R, Rickmann M, Macke L, Borchers S, Figueiredo C, Schambach A, Gullberg U, Provasi E, Bonini C, Ganser A, Woelfel T, Stripecke R.

Hum Gene Ther. 2013 Feb;24(2):220-37. doi: 10.1089/hum.2012.128.

26.

Ultranet: efficient solver for the sparse inverse covariance selection problem in gene network modeling.

Järvstråt L, Johansson M, Gullberg U, Nilsson B.

Bioinformatics. 2013 Feb 15;29(4):511-2. doi: 10.1093/bioinformatics/bts717. Epub 2012 Dec 24.

PMID:
23267175
27.

Stat1 activation attenuates IL-6 induced Stat3 activity but does not alter apoptosis sensitivity in multiple myeloma.

Dimberg LY, Dimberg A, Ivarsson K, Fryknäs M, Rickardson L, Tobin G, Ekman S, Larsson R, Gullberg U, Nilsson K, Öberg F, Wiklund HJ.

BMC Cancer. 2012 Jul 28;12:318. doi: 10.1186/1471-2407-12-318.

28.

The p53 target gene TRIM22 directly or indirectly interacts with the translation initiation factor eIF4E and inhibits the binding of eIF4E to eIF4G.

Petersson J, Ageberg M, Sandén C, Olofsson T, Gullberg U, Drott K.

Biol Cell. 2012 Aug;104(8):462-75. doi: 10.1111/boc.201100099. Epub 2012 May 31.

PMID:
22509910
29.

The leukemia associated nuclear corepressor ETO homologue genes MTG16 and MTGR1 are regulated differently in hematopoietic cells.

Ajore R, Kumar P, Dhanda RS, Gullberg U, Olsson I.

BMC Mol Biol. 2012 Mar 23;13:11. doi: 10.1186/1471-2199-13-11.

30.

The leukemia associated ETO nuclear repressor gene is regulated by the GATA-1 transcription factor in erythroid/megakaryocytic cells.

Ajore R, Dhanda RS, Gullberg U, Olsson I.

BMC Mol Biol. 2010 May 20;11:38. doi: 10.1186/1471-2199-11-38.

31.

Wilms' tumor gene 1 protein represses the expression of the tumor suppressor interferon regulatory factor 8 in human hematopoietic progenitors and in leukemic cells.

Vidovic K, Svensson E, Nilsson B, Thuresson B, Olofsson T, Lennartsson A, Gullberg U.

Leukemia. 2010 May;24(5):992-1000. doi: 10.1038/leu.2010.33. Epub 2010 Mar 18.

PMID:
20237505
32.

The human IFN-inducible p53 target gene TRIM22 colocalizes with the centrosome independently of cell cycle phase.

Petersson J, Lönnbro P, Herr AM, Mörgelin M, Gullberg U, Drott K.

Exp Cell Res. 2010 Feb 15;316(4):568-79. doi: 10.1016/j.yexcr.2009.12.007. Epub 2009 Dec 16.

PMID:
20006605
33.

Resistance to Melampsora larici-epitea leaf rust in Salix: analyses of quantitative trait loci.

Rönnberg-Wästljung AC, Samils B, Tsarouhas V, Gullberg U.

J Appl Genet. 2008;49(4):321-31. doi: 10.1007/BF03195630.

PMID:
19029679
34.

Identification of a novel and myeloid specific role of the leukemia-associated fusion protein DEK-NUP214 leading to increased protein synthesis.

Ageberg M, Drott K, Olofsson T, Gullberg U, Lindmark A.

Genes Chromosomes Cancer. 2008 Apr;47(4):276-87. doi: 10.1002/gcc.20531.

PMID:
18181180
35.

Gene expression analysis of BCR/ABL1-dependent transcriptional response reveals enrichment for genes involved in negative feedback regulation.

Håkansson P, Nilsson B, Andersson A, Lassen C, Gullberg U, Fioretos T.

Genes Chromosomes Cancer. 2008 Apr;47(4):267-75. doi: 10.1002/gcc.20528.

PMID:
18181176
36.

The hDMP1 tumor suppressor is a new WT1 target in myeloid leukemias.

Tschan MP, Gullberg U, Shan D, Torbett BE, Fey MF, Tobler A.

Leukemia. 2008 May;22(5):1087-90. Epub 2007 Nov 1. No abstract available.

PMID:
17972942
37.

Regulation of the interferon-inducible p53 target gene TRIM22 (Staf50) in human T lymphocyte activation.

Obad S, Olofsson T, Mechti N, Gullberg U, Drott K.

J Interferon Cytokine Res. 2007 Oct;27(10):857-64.

PMID:
17970695
38.

Quantitative trait loci controlling cyanogenic glucoside and dry matter content in cassava (Manihot esculenta Crantz) roots.

Balyejusa Kizito E, Rönnberg-Wästljung AC, Egwang T, Gullberg U, Fregene M, Westerbergh A.

Hereditas. 2007 Sep;144(4):129-36.

39.

Deregulation of the Wilms' tumour gene 1 protein (WT1) by BCR/ABL1 mediates resistance to imatinib in human leukaemia cells.

Svensson E, Vidovic K, Lassen C, Richter J, Olofsson T, Fioretos T, Gullberg U.

Leukemia. 2007 Dec;21(12):2485-94. Epub 2007 Aug 30.

PMID:
17728783
40.

The Wilms' tumor gene 1 (WT1) induces expression of the N-myc downstream regulated gene 2 (NDRG2).

Svensson E, Vidovic K, Olofsson T, Vallon-Christersson J, Borg A, Gullberg U.

DNA Cell Biol. 2007 Aug;26(8):589-97.

PMID:
17688410
41.

Expression of the IFN-inducible p53-target gene TRIM22 is down-regulated during erythroid differentiation of human bone marrow.

Obad S, Olofsson T, Mechti N, Gullberg U, Drott K.

Leuk Res. 2007 Jul;31(7):995-1001. Epub 2007 Jan 24.

PMID:
17257675
42.
43.

The involvement of cellular proliferation status in the expression of the human proto-oncogene DEK.

Ageberg M, Gullberg U, Lindmark A.

Haematologica. 2006 Feb;91(2):268-9.

44.

Functional and biochemical characterization of epithelial bactericidal/permeability-increasing protein.

Canny G, Cario E, Lennartsson A, Gullberg U, Brennan C, Levy O, Colgan SP.

Am J Physiol Gastrointest Liver Physiol. 2006 Mar;290(3):G557-67. Epub 2005 Nov 10.

45.
46.

DNA-binding dependent and independent functions of WT1 protein during human hematopoiesis.

Svensson E, Eriksson H, Gekas C, Olofsson T, Richter J, Gullberg U.

Exp Cell Res. 2005 Aug 1;308(1):211-21.

PMID:
15907324
47.

Biosynthetic profiles of neutrophil serine proteases in a human bone marrow-derived cellular myeloid differentiation model.

Garwicz D, Lennartsson A, Jacobsen SE, Gullberg U, Lindmark A.

Haematologica. 2005 Jan;90(1):38-44.

48.

A murine antibacterial ortholog to human bactericidal/permeability-increasing protein (BPI) is expressed in testis, epididymis, and bone marrow.

Lennartsson A, Pieters K, Vidovic K, Gullberg U.

J Leukoc Biol. 2005 Mar;77(3):369-77. Epub 2004 Dec 8.

PMID:
15590754
49.
50.

Identification of genes differentially regulated by the P210 BCR/ABL1 fusion oncogene using cDNA microarrays.

Håkansson P, Segal D, Lassen C, Gullberg U, Morse HC 3rd, Fioretos T, Meltzer PS.

Exp Hematol. 2004 May;32(5):476-82.

PMID:
15145216

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