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Items: 9


Human DNA Helicase B as a Candidate for Unwinding Secondary CGG Repeat Structures at the Fragile X Mental Retardation Gene.

Guler GD, Rosenwaks Z, Gerhardt J.

Front Mol Neurosci. 2018 Apr 30;11:138. doi: 10.3389/fnmol.2018.00138. eCollection 2018.


Repression of Stress-Induced LINE-1 Expression Protects Cancer Cell Subpopulations from Lethal Drug Exposure.

Guler GD, Tindell CA, Pitti R, Wilson C, Nichols K, KaiWai Cheung T, Kim HJ, Wongchenko M, Yan Y, Haley B, Cuellar T, Webster J, Alag N, Hegde G, Jackson E, Nance TL, Giresi PG, Chen KB, Liu J, Jhunjhunwala S, Settleman J, Stephan JP, Arnott D, Classon M.

Cancer Cell. 2017 Aug 14;32(2):221-237.e13. doi: 10.1016/j.ccell.2017.07.002. Epub 2017 Aug 3.


An Alternative Approach to ChIP-Seq Normalization Enables Detection of Genome-Wide Changes in Histone H3 Lysine 27 Trimethylation upon EZH2 Inhibition.

Egan B, Yuan CC, Craske ML, Labhart P, Guler GD, Arnott D, Maile TM, Busby J, Henry C, Kelly TK, Tindell CA, Jhunjhunwala S, Zhao F, Hatton C, Bryant BM, Classon M, Trojer P.

PLoS One. 2016 Nov 22;11(11):e0166438. doi: 10.1371/journal.pone.0166438. eCollection 2016.


An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells.

Vinogradova M, Gehling VS, Gustafson A, Arora S, Tindell CA, Wilson C, Williamson KE, Guler GD, Gangurde P, Manieri W, Busby J, Flynn EM, Lan F, Kim HJ, Odate S, Cochran AG, Liu Y, Wongchenko M, Yang Y, Cheung TK, Maile TM, Lau T, Costa M, Hegde GV, Jackson E, Pitti R, Arnott D, Bailey C, Bellon S, Cummings RT, Albrecht BK, Harmange JC, Kiefer JR, Trojer P, Classon M.

Nat Chem Biol. 2016 Jul;12(7):531-8. doi: 10.1038/nchembio.2085. Epub 2016 May 23.


Human DNA helicase B interacts with the replication initiation protein Cdc45 and facilitates Cdc45 binding onto chromatin.

Gerhardt J, Guler GD, Fanning E.

Exp Cell Res. 2015 Jun 10;334(2):283-93. doi: 10.1016/j.yexcr.2015.04.014. Epub 2015 Apr 29.


Mass spectrometric quantification of histone post-translational modifications by a hybrid chemical labeling method.

Maile TM, Izrael-Tomasevic A, Cheung T, Guler GD, Tindell C, Masselot A, Liang J, Zhao F, Trojer P, Classon M, Arnott D.

Mol Cell Proteomics. 2015 Apr;14(4):1148-58. doi: 10.1074/mcp.O114.046573. Epub 2015 Feb 13.


Human DNA helicase B (HDHB) binds to replication protein A and facilitates cellular recovery from replication stress.

Guler GD, Liu H, Vaithiyalingam S, Arnett DR, Kremmer E, Chazin WJ, Fanning E.

J Biol Chem. 2012 Feb 24;287(9):6469-81. doi: 10.1074/jbc.M111.324582. Epub 2011 Dec 21.


The replisome: a nanomachine or a dynamic dance of protein partners?

Guler GD, Fanning E.

Cell Cycle. 2010 May;9(9):1680-1. Epub 2010 May 1. No abstract available.


Structural mechanism of RPA loading on DNA during activation of a simple pre-replication complex.

Jiang X, Klimovich V, Arunkumar AI, Hysinger EB, Wang Y, Ott RD, Guler GD, Weiner B, Chazin WJ, Fanning E.

EMBO J. 2006 Nov 29;25(23):5516-26. Epub 2006 Nov 16.

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