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Items: 21

1.

Detection of Aggregation-Competent Tau in Neuron-Derived Extracellular Vesicles.

Guix FX, Corbett GT, Cha DJ, Mustapic M, Liu W, Mengel D, Chen Z, Aikawa E, Young-Pearse T, Kapogiannis D, Selkoe DJ, Walsh DM.

Int J Mol Sci. 2018 Feb 27;19(3). pii: E663. doi: 10.3390/ijms19030663.

2.

Could blocking the formation of amyloid channels rescue Alzheimer's phenotype?

Guix FX, Dotti CG.

EMBO Mol Med. 2018 Jan;10(1):7-9. doi: 10.15252/emmm.201708491. No abstract available.

3.

Correction: Tetraspanin 6: A novel regulator of hippocampal synaptic transmission and long term plasticity.

Salas IH, Callaerts-Vegh Z, Arranz AM, Guix FX, D'Hooge R, Esteban JA, De Strooper B, Dotti CG.

PLoS One. 2017 Oct 24;12(10):e0187179. doi: 10.1371/journal.pone.0187179. eCollection 2017.

4.

Correction: Tetraspanin 6: A novel regulator of hippocampal synaptic transmission and long term plasticity.

Salas IH, Callaerts-Vegh Z, Arranz AM, Guix FX, D'Hooge R, Esteban JA, De Strooper B, Dotti CG.

PLoS One. 2017 Jul 7;12(7):e0178016. doi: 10.1371/journal.pone.0178016. eCollection 2017.

5.

Tetraspanin 6: a pivotal protein of the multiple vesicular body determining exosome release and lysosomal degradation of amyloid precursor protein fragments.

Guix FX, Sannerud R, Berditchevski F, Arranz AM, Horré K, Snellinx A, Thathiah A, Saido T, Saito T, Rajesh S, Overduin M, Kumar-Singh S, Radaelli E, Corthout N, Colombelli J, Tosi S, Munck S, Salas IH, Annaert W, De Strooper B.

Mol Neurodegener. 2017 Mar 10;12(1):25. doi: 10.1186/s13024-017-0165-0.

6.

Tetraspanin 6: A novel regulator of hippocampal synaptic transmission and long term plasticity.

Salas IH, Callaerts-Vegh Z, Arranz AM, Guix FX, D'Hooge R, Esteban JA, De Strooper B, Dotti CG.

PLoS One. 2017 Feb 16;12(2):e0171968. doi: 10.1371/journal.pone.0171968. eCollection 2017. Erratum in: PLoS One. 2017 Jul 7;12 (7):e0178016. PLoS One. 2017 Oct 24;12 (10 ):e0187179.

7.

Physiological Control of Nitric Oxide in Neuronal BACE1 Translation by Heme-Regulated eIF2α Kinase HRI Induces Synaptogenesis.

Ill-Raga G, Tajes M, Busquets-García A, Ramos-Fernández E, Vargas LM, Bosch-Morató M, Guivernau B, Valls-Comamala V, Eraso-Pichot A, Guix FX, Fandos C, Rosen MD, Rabinowitz MH, Maldonado R, Alvarez AR, Ozaita A, Muñoz FJ.

Antioxid Redox Signal. 2015 May 20;22(15):1295-307. doi: 10.1089/ars.2014.6080. Epub 2015 Mar 25.

PMID:
25706765
8.

Fibrinogen nitrotyrosination after ischemic stroke impairs thrombolysis and promotes neuronal death.

Ill-Raga G, Palomer E, Ramos-Fernández E, Guix FX, Bosch-Morató M, Guivernau B, Tajes M, Valls-Comamala V, Jiménez-Conde J, Ois A, Pérez-Asensio F, Reyes-Navarro M, Caballo C, Gil-Gómez G, Lopez-Vilchez I, Galan AM, Alameda F, Escolar G, Opazo C, Planas AM, Roquer J, Valverde MA, Muñoz FJ.

Biochim Biophys Acta. 2015 Mar;1852(3):421-8. doi: 10.1016/j.bbadis.2014.12.007. Epub 2014 Dec 12.

9.

Methylglyoxal produced by amyloid-β peptide-induced nitrotyrosination of triosephosphate isomerase triggers neuronal death in Alzheimer's disease.

Tajes M, Eraso-Pichot A, Rubio-Moscardó F, Guivernau B, Ramos-Fernández E, Bosch-Morató M, Guix FX, Clarimón J, Miscione GP, Boada M, Gil-Gómez G, Suzuki T, Molina H, Villà-Freixa J, Vicente R, Muñoz FJ.

J Alzheimers Dis. 2014;41(1):273-88. doi: 10.3233/JAD-131685.

PMID:
24614897
10.

Nitro-oxidative stress after neuronal ischemia induces protein nitrotyrosination and cell death.

Tajes M, Ill-Raga G, Palomer E, Ramos-Fernández E, Guix FX, Bosch-Morató M, Guivernau B, Jiménez-Conde J, Ois A, Pérez-Asensio F, Reyes-Navarro M, Caballo C, Galán AM, Alameda F, Escolar G, Opazo C, Planas A, Roquer J, Valverde MA, Muñoz FJ.

Oxid Med Cell Longev. 2013;2013:826143. doi: 10.1155/2013/826143. Epub 2013 Aug 1.

11.

The pathophysiology of triose phosphate isomerase dysfunction in Alzheimer's disease.

Tajes M, Guivernau B, Ramos-Fernández E, Bosch-Morató M, Palomer E, Guix FX, Muñoz FJ.

Histol Histopathol. 2013 Jan;28(1):43-51. doi: 10.14670/HH-28.43. Review.

PMID:
23233058
12.

Modification of γ-secretase by nitrosative stress links neuronal ageing to sporadic Alzheimer's disease.

Guix FX, Wahle T, Vennekens K, Snellinx A, Chávez-Gutiérrez L, Ill-Raga G, Ramos-Fernandez E, Guardia-Laguarta C, Lleó A, Arimon M, Berezovska O, Muñoz FJ, Dotti CG, De Strooper B.

EMBO Mol Med. 2012 Jul;4(7):660-73. doi: 10.1002/emmm.201200243. Epub 2012 May 2.

13.

Down-regulation of the ATP-binding cassette transporter 2 (Abca2) reduces amyloid-β production by altering Nicastrin maturation and intracellular localization.

Michaki V, Guix FX, Vennekens K, Munck S, Dingwall C, Davis JB, Townsend DM, Tew KD, Feiguin F, De Strooper B, Dotti CG, Wahle T.

J Biol Chem. 2012 Jan 6;287(2):1100-11. doi: 10.1074/jbc.M111.288258. Epub 2011 Nov 15.

14.

Alterations in phosphatidylethanolamine levels affect the generation of Aβ.

Nesic I, Guix FX, Vennekens K, Michaki V, Van Veldhoven PP, Feiguin F, De Strooper B, Dotti CG, Wahle T.

Aging Cell. 2012 Feb;11(1):63-72. doi: 10.1111/j.1474-9726.2011.00760.x. Epub 2011 Nov 28.

15.

Activation of PKR causes amyloid ß-peptide accumulation via de-repression of BACE1 expression.

Ill-Raga G, Palomer E, Wozniak MA, Ramos-Fernández E, Bosch-Morató M, Tajes M, Guix FX, Galán JJ, Clarimón J, Antúnez C, Real LM, Boada M, Itzhaki RF, Fandos C, Muñoz FJ.

PLoS One. 2011;6(6):e21456. doi: 10.1371/journal.pone.0021456. Epub 2011 Jun 28.

16.

Amyloid-β peptide fibrils induce nitro-oxidative stress in neuronal cells.

Ill-Raga G, Ramos-Fernández E, Guix FX, Tajes M, Bosch-Morató M, Palomer E, Godoy J, Belmar S, Cerpa W, Simpkins JW, Inestrosa And NC, Muñoz FJ.

J Alzheimers Dis. 2010;22(2):641-52. doi: 10.3233/JAD-2010-100474.

PMID:
20858976
17.

Amyloid-dependent triosephosphate isomerase nitrotyrosination induces glycation and tau fibrillation.

Guix FX, Ill-Raga G, Bravo R, Nakaya T, de Fabritiis G, Coma M, Miscione GP, Villà-Freixa J, Suzuki T, Fernàndez-Busquets X, Valverde MA, de Strooper B, Muñoz FJ.

Brain. 2009 May;132(Pt 5):1335-45. doi: 10.1093/brain/awp023. Epub 2009 Feb 27.

PMID:
19251756
18.

Oxidative stress triggers the amyloidogenic pathway in human vascular smooth muscle cells.

Coma M, Guix FX, Ill-Raga G, Uribesalgo I, Alameda F, Valverde MA, Muñoz FJ.

Neurobiol Aging. 2008 Jul;29(7):969-80. Epub 2007 Feb 15.

PMID:
17306421
19.

The physiology and pathophysiology of nitric oxide in the brain.

Guix FX, Uribesalgo I, Coma M, Muñoz FJ.

Prog Neurobiol. 2005 Jun;76(2):126-52. Review.

PMID:
16115721
20.

Lack of oestrogen protection in amyloid-mediated endothelial damage due to protein nitrotyrosination.

Coma M, Guix FX, Uribesalgo I, Espuña G, Solé M, Andreu D, Muñoz FJ.

Brain. 2005 Jul;128(Pt 7):1613-21. Epub 2005 Apr 7.

PMID:
15817516
21.

Plasma membrane voltage-dependent anion channel mediates antiestrogen-activated maxi Cl- currents in C1300 neuroblastoma cells.

Bahamonde MI, Fernández-Fernández JM, Guix FX, Vázquez E, Valverde MA.

J Biol Chem. 2003 Aug 29;278(35):33284-9. Epub 2003 Jun 5.

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