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Items: 30


Multiparametric radiobiological assays show that variation of X-ray energy strongly impacts relative biological effectiveness: comparison between 220 kV and 4 MV.

Paget V, Ben Kacem M, Dos Santos M, Benadjaoud MA, Soysouvanh F, Buard V, Georges T, Vaurijoux A, Gruel G, François A, Guipaud O, Milliat F.

Sci Rep. 2019 Oct 4;9(1):14328. doi: 10.1038/s41598-019-50908-4.


Lung Stereotactic Arc Therapy in Mice: Development of Radiation Pneumopathy and Influence of HIF-1α Endothelial Deletion.

Lavigne J, Suissa A, Verger N, Dos Santos M, Benadjaoud M, Mille-Hamard L, Momken I, Soysouvanh F, Buard V, Guipaud O, Paget V, Tarlet G, Milliat F, François A.

Int J Radiat Oncol Biol Phys. 2019 Jun 1;104(2):279-290. doi: 10.1016/j.ijrobp.2019.01.081. Epub 2019 Jan 29.


Temporal clustering analysis of endothelial cell gene expression following exposure to a conventional radiotherapy dose fraction using Gaussian process clustering.

Heinonen M, Milliat F, Benadjaoud MA, François A, Buard V, Tarlet G, d'Alché-Buc F, Guipaud O.

PLoS One. 2018 Oct 3;13(10):e0204960. doi: 10.1371/journal.pone.0204960. eCollection 2018.


Importance of dosimetry protocol for cell irradiation on a low X-rays facility and consequences for the biological response.

Dos Santos M, Paget V, Ben Kacem M, Trompier F, Benadjaoud MA, François A, Guipaud O, Benderitter M, Milliat F.

Int J Radiat Biol. 2018 Jun;94(6):597-606. doi: 10.1080/09553002.2018.1466205.


The importance of the vascular endothelial barrier in the immune-inflammatory response induced by radiotherapy.

Guipaud O, Jaillet C, Clément-Colmou K, François A, Supiot S, Milliat F.

Br J Radiol. 2018 Sep;91(1089):20170762. doi: 10.1259/bjr.20170762. Epub 2018 Apr 20. Review.


HIF-1α Deletion in the Endothelium, but Not in the Epithelium, Protects From Radiation-Induced Enteritis.

Toullec A, Buard V, Rannou E, Tarlet G, Guipaud O, Robine S, Iruela-Arispe ML, François A, Milliat F.

Cell Mol Gastroenterol Hepatol. 2017 Aug 16;5(1):15-30. doi: 10.1016/j.jcmgh.2017.08.001. eCollection 2018.


Conditional Plasminogen Activator Inhibitor Type 1 Deletion in the Endothelial Compartment Has No Beneficial Effect on Radiation-Induced Whole-Lung Damage in Mice.

Lavigne J, Soysouvanh F, Buard V, Tarlet G, Guipaud O, Paget V, Milliat F, François A.

Int J Radiat Oncol Biol Phys. 2017 Nov 15;99(4):972-982. doi: 10.1016/j.ijrobp.2017.07.007. Epub 2017 Jul 11.


Radiation-induced changes in the glycome of endothelial cells with functional consequences.

Jaillet C, Morelle W, Slomianny MC, Paget V, Tarlet G, Buard V, Selbonne S, Caffin F, Rannou E, Martinez P, François A, Foulquier F, Allain F, Milliat F, Guipaud O.

Sci Rep. 2017 Jul 13;7(1):5290. doi: 10.1038/s41598-017-05563-y.


Endothelial Hey2 deletion reduces endothelial-to-mesenchymal transition and mitigates radiation proctitis in mice.

Mintet E, Lavigne J, Paget V, Tarlet G, Buard V, Guipaud O, Sabourin JC, Iruela-Arispe ML, Milliat F, François A.

Sci Rep. 2017 Jul 10;7(1):4933. doi: 10.1038/s41598-017-05389-8.


Proteome changes in rat serum after a chronic ingestion of enriched uranium: Toward a biological signature of internal contamination and radiological effect.

Petitot F, Frelon S, Chambon C, Paquet F, Guipaud O.

Toxicol Lett. 2016 Aug 22;257:44-59. doi: 10.1016/j.toxlet.2016.05.026. Epub 2016 Jun 5.


In vivo evidence for an endothelium-dependent mechanism in radiation-induced normal tissue injury.

Rannou E, François A, Toullec A, Guipaud O, Buard V, Tarlet G, Mintet E, Jaillet C, Iruela-Arispe ML, Benderitter M, Sabourin JC, Milliat F.

Sci Rep. 2015 Oct 29;5:15738. doi: 10.1038/srep15738.


A new phosphorylated form of Ku70 identified in resistant leukemic cells confers fast but unfaithful DNA repair in cancer cell lines.

Bouley J, Saad L, Grall R, Schellenbauer A, Biard D, Paget V, Morel-Altmeyer S, Guipaud O, Chambon C, Salles B, Maloum K, Merle-Béral H, Chevillard S, Delic J.

Oncotarget. 2015 Sep 29;6(29):27980-8000. doi: 10.18632/oncotarget.4735.


Identification of Endothelial-to-Mesenchymal Transition as a Potential Participant in Radiation Proctitis.

Mintet E, Rannou E, Buard V, West G, Guipaud O, Tarlet G, Sabourin JC, Benderitter M, Fiocchi C, Milliat F, François A.

Am J Pathol. 2015 Sep;185(9):2550-62. doi: 10.1016/j.ajpath.2015.04.028. Epub 2015 Jul 14.


Detecting time periods of differential gene expression using Gaussian processes: an application to endothelial cells exposed to radiotherapy dose fraction.

Heinonen M, Guipaud O, Milliat F, Buard V, Micheau B, Tarlet G, Benderitter M, Zehraoui F, d'Alché-Buc F.

Bioinformatics. 2015 Mar 1;31(5):728-35. doi: 10.1093/bioinformatics/btu699. Epub 2014 Oct 28.


Radiation-induced changes in levels of selected proteins in peripheral blood serum of breast cancer patients as a potential triage biodosimeter for large-scale radiological emergencies.

Deperas-Kaminska M, Bajinskis A, Marczyk M, Polanska J, Wersäll P, Lidbrink E, Ainsbury EA, Guipaud O, Benderitter M, Haghdoost S, Wojcik A.

Health Phys. 2014 Dec;107(6):555-63. doi: 10.1097/HP.0000000000000158.


Serum Proteome Analysis for Profiling Predictive Protein Markers Associated with the Severity of Skin Lesions Induced by Ionizing Radiation.

Chaze T, Hornez L, Chambon C, Haddad I, Vinh J, Peyrat JP, Benderitter M, Guipaud O.

Proteomes. 2013 Jul 10;1(2):40-69. doi: 10.3390/proteomes1020040.


Inflammation and immunity in radiation damage to the gut mucosa.

François A, Milliat F, Guipaud O, Benderitter M.

Biomed Res Int. 2013;2013:123241. doi: 10.1155/2013/123241. Epub 2013 Mar 19. Review.


Serum and plasma proteomics and its possible use as detector and predictor of radiation diseases.

Guipaud O.

Adv Exp Med Biol. 2013;990:61-86. doi: 10.1007/978-94-007-5896-4_4. Review.


Protective effect of geranylgeranylacetone against radiation-induced delayed effects on human keratinocytes.

Isoir M, Roque T, Squiban C, Milliat F, Mondon P, Mas-Chamberlin C, Benderitter M, Guipaud O, Tamarat R.

Radiat Res. 2013 Feb;179(2):232-42. doi: 10.1667/RR2717.1. Epub 2013 Jan 4.


Alteration of the serum N-glycome of mice locally exposed to high doses of ionizing radiation.

Chaze T, Slomianny MC, Milliat F, Tarlet G, Lefebvre-Darroman T, Gourmelon P, Bey E, Benderitter M, Michalski JC, Guipaud O.

Mol Cell Proteomics. 2013 Feb;12(2):283-301. doi: 10.1074/mcp.M111.014639. Epub 2012 Nov 12.


Protein biomarkers for radiation exposure: towards a proteomic approach as a new investigation tool.

Guipaud O, Benderitter M.

Ann Ist Super Sanita. 2009;45(3):278-86. Review.


Pravastatin limits radiation-induced vascular dysfunction in the skin.

Holler V, Buard V, Gaugler MH, Guipaud O, Baudelin C, Sache A, Perez Mdel R, Squiban C, Tamarat R, Milliat F, Benderitter M.

J Invest Dermatol. 2009 May;129(5):1280-91. doi: 10.1038/jid.2008.360. Epub 2009 Feb 12.


Time-course analysis of mouse serum proteome changes following exposure of the skin to ionizing radiation.

Guipaud O, Holler V, Buard V, Tarlet G, Royer N, Vinh J, Benderitter M.

Proteomics. 2007 Nov;7(21):3992-4002.


An in vitro enzymatic assay coupled to proteomics analysis reveals a new DNA processing activity for Ewing sarcoma and TAF(II)68 proteins.

Guipaud O, Guillonneau F, Labas V, Praseuth D, Rossier J, Lopez B, Bertrand P.

Proteomics. 2006 Nov;6(22):5962-72.


Mutagenicity of non-homologous end joining DNA repair in a resistant subset of human chronic lymphocytic leukaemia B cells.

Deriano L, Merle-Béral H, Guipaud O, Sabatier L, Delic J.

Br J Haematol. 2006 Jun;133(5):520-5.


Human chronic lymphocytic leukemia B cells can escape DNA damage-induced apoptosis through the nonhomologous end-joining DNA repair pathway.

Deriano L, Guipaud O, Merle-Béral H, Binet JL, Ricoul M, Potocki-Veronese G, Favaudon V, Maciorowski Z, Muller C, Salles B, Sabatier L, Delic J.

Blood. 2005 Jun 15;105(12):4776-83. Epub 2005 Feb 17.


B-cell chronic lymphocytic leukaemia: a polymorphic family unified by genomic features.

Guipaud O, Deriano L, Salin H, Vallat L, Sabatier L, Merle-Béral H, Delic J.

Lancet Oncol. 2003 Aug;4(8):505-14. Review.


DNA gyrase from Thermotoga maritima.

Guipaud O, Forterre P.

Methods Enzymol. 2001;334:162-71. No abstract available.


Both DNA gyrase and reverse gyrase are present in the hyperthermophilic bacterium Thermotoga maritima.

Guipaud O, Marguet E, Noll KM, de la Tour CB, Forterre P.

Proc Natl Acad Sci U S A. 1997 Sep 30;94(20):10606-11.


A gyrB-like gene from the hyperthermophilic bacterion Thermotoga maritima.

Guipaud O, Labedan B, Forterre P.

Gene. 1996 Sep 26;174(1):121-8.


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