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Items: 1 to 50 of 94

1.

Antitumor Activity of a Binary EGFR/DNA Targeting Strategy Overcomes Resistance of Glioblastoma Stem cells to Temozolomide.

Sharifi Z, Abdulkarim B, Meehan B, Rak J, Daniel P, Schmitt J, Lauzon N, Eppert K, Duncan HM, Petrecca K, Guiot MC, Jean-Claude BJ, Sabri S.

Clin Cancer Res. 2019 Sep 20. pii: clincanres.0955.2019. doi: 10.1158/1078-0432.CCR-19-0955. [Epub ahead of print]

PMID:
31540977
2.

eIF4A inhibitors suppress cell cycle feedback response and acquired resistance to CDK4/6 inhibition in cancer.

Kong T, Xue Y, Cencic R, Zhu X, Monast A, Fu Z, Pilon V, Sangwan V, Guiot MC, Foulkes WD, Porco JA, Park M, Pelletier J, Huang S.

Mol Cancer Ther. 2019 Aug 8. pii: molcanther.0162.2019. doi: 10.1158/1535-7163.MCT-19-0162. [Epub ahead of print]

PMID:
31395685
3.

Rheumatoid Meningitis Presenting With Acute Parkinsonism and Protracted Non-convulsive Seizures: An Unusual Case Presentation and Review of Treatment Strategies.

Pellerin D, Wodkowski M, Guiot MC, AlDhukair H, Blotsky A, Karamchandani J, Vinet E, Lafontaine AL, Lubarsky S.

Front Neurol. 2019 Feb 27;10:163. doi: 10.3389/fneur.2019.00163. eCollection 2019.

4.

Spatially distinct tumor immune microenvironments stratify triple-negative breast cancers.

Gruosso T, Gigoux M, Manem VSK, Bertos N, Zuo D, Perlitch I, Saleh SMI, Zhao H, Souleimanova M, Johnson RM, Monette A, Ramos VM, Hallett MT, Stagg J, Lapointe R, Omeroglu A, Meterissian S, Buisseret L, Van den Eynden G, Salgado R, Guiot MC, Haibe-Kains B, Park M.

J Clin Invest. 2019 Apr 1;129(4):1785-1800. doi: 10.1172/JCI96313. Epub 2019 Mar 18.

5.

Infiltration of CD8+ T cells into tumor cell clusters in triple-negative breast cancer.

Li X, Gruosso T, Zuo D, Omeroglu A, Meterissian S, Guiot MC, Salazar A, Park M, Levine H.

Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3678-3687. doi: 10.1073/pnas.1817652116. Epub 2019 Feb 7.

6.

CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary.

Xue Y, Meehan B, Macdonald E, Venneti S, Wang XQD, Witkowski L, Jelinic P, Kong T, Martinez D, Morin G, Firlit M, Abedini A, Johnson RM, Cencic R, Patibandla J, Chen H, Papadakis AI, Auguste A, de Rink I, Kerkhoven RM, Bertos N, Gotlieb WH, Clarke BA, Leary A, Witcher M, Guiot MC, Pelletier J, Dostie J, Park M, Judkins AR, Hass R, Levine DA, Rak J, Vanderhyden B, Foulkes WD, Huang S.

Nat Commun. 2019 Feb 4;10(1):558. doi: 10.1038/s41467-018-06958-9.

7.

SMARCA4 loss is synthetic lethal with CDK4/6 inhibition in non-small cell lung cancer.

Xue Y, Meehan B, Fu Z, Wang XQD, Fiset PO, Rieker R, Levins C, Kong T, Zhu X, Morin G, Skerritt L, Herpel E, Venneti S, Martinez D, Judkins AR, Jung S, Camilleri-Broet S, Gonzalez AV, Guiot MC, Lockwood WW, Spicer JD, Agaimy A, Pastor WA, Dostie J, Rak J, Foulkes WD, Huang S.

Nat Commun. 2019 Feb 4;10(1):557. doi: 10.1038/s41467-019-08380-1.

8.

Development and first in-human use of a Raman spectroscopy guidance system integrated with a brain biopsy needle.

Desroches J, Lemoine É, Pinto M, Marple E, Urmey K, Diaz R, Guiot MC, Wilson BC, Petrecca K, Leblond F.

J Biophotonics. 2019 Mar;12(3):e201800396. doi: 10.1002/jbio.201800396. Epub 2019 Jan 28.

PMID:
30636032
9.

In vivo metabotropic glutamate receptor type 5 abnormalities localize the epileptogenic zone in mesial temporal lobe epilepsy.

Lam J, DuBois JM, Rowley J, González-Otárula KA, Soucy JP, Massarweh G, Hall JA, Guiot MC, Rosa-Neto P, Kobayashi E.

Ann Neurol. 2019 Feb;85(2):218-228. doi: 10.1002/ana.25404. Epub 2019 Jan 20.

PMID:
30597619
10.

Dual MAPK Inhibition Is an Effective Therapeutic Strategy for a Subset of Class II BRAF Mutant Melanomas.

Dankner M, Lajoie M, Moldoveanu D, Nguyen TT, Savage P, Rajkumar S, Huang X, Lvova M, Protopopov A, Vuzman D, Hogg D, Park M, Guiot MC, Petrecca K, Mihalcioiu C, Watson IR, Siegel PM, Rose AAN.

Clin Cancer Res. 2018 Dec 15;24(24):6483-6494. doi: 10.1158/1078-0432.CCR-17-3384. Epub 2018 Jun 14.

PMID:
29903896
11.

KIBRA (WWC1) Is a Metastasis Suppressor Gene Affected by Chromosome 5q Loss in Triple-Negative Breast Cancer.

Knight JF, Sung VYC, Kuzmin E, Couzens AL, de Verteuil DA, Ratcliffe CDH, Coelho PP, Johnson RM, Samavarchi-Tehrani P, Gruosso T, Smith HW, Lee W, Saleh SM, Zuo D, Zhao H, Guiot MC, Davis RR, Gregg JP, Moraes C, Gingras AC, Park M.

Cell Rep. 2018 Mar 20;22(12):3191-3205. doi: 10.1016/j.celrep.2018.02.095.

12.

A new method using Raman spectroscopy for in vivo targeted brain cancer tissue biopsy.

Desroches J, Jermyn M, Pinto M, Picot F, Tremblay MA, Obaid S, Marple E, Urmey K, Trudel D, Soulez G, Guiot MC, Wilson BC, Petrecca K, Leblond F.

Sci Rep. 2018 Jan 29;8(1):1792. doi: 10.1038/s41598-018-20233-3.

13.

Prognostic factors for progression in atypical meningioma.

Shakir SI, Souhami L, Petrecca K, Mansure JJ, Singh K, Panet-Raymond V, Shenouda G, Al-Odaini AA, Abdulkarim B, Guiot MC.

J Neurosurg. 2018 Nov 1;129(5):1240-1248. doi: 10.3171/2017.6.JNS17120.

PMID:
29350599
14.

Cavernous sinus syndrome associated with metastatic colorectal cancer and perineural spread along the trigeminal nerve.

Nassrallah G, Sun V, Guiot MC, Mikhail M, Arthurs B.

Am J Ophthalmol Case Rep. 2017 Mar 14;6:67-70. doi: 10.1016/j.ajoc.2016.11.011. eCollection 2017 Jun.

15.

Novel NAPRT specific antibody identifies small cell lung cancer and neuronal cancers as promising clinical indications for a NAMPT inhibitor/niacin co-administration strategy.

Cole J, Guiot MC, Gravel M, Bernier C, Shore GC, Roulston A.

Oncotarget. 2017 Sep 12;8(44):77846-77859. doi: 10.18632/oncotarget.20840. eCollection 2017 Sep 29.

16.

A Targetable EGFR-Dependent Tumor-Initiating Program in Breast Cancer.

Savage P, Blanchet-Cohen A, Revil T, Badescu D, Saleh SMI, Wang YC, Zuo D, Liu L, Bertos NR, Munoz-Ramos V, Basik M, Petrecca K, Asselah J, Meterissian S, Guiot MC, Omeroglu A, Kleinman CL, Park M, Ragoussis J.

Cell Rep. 2017 Oct 31;21(5):1140-1149. doi: 10.1016/j.celrep.2017.10.015.

17.

CUX1 stimulates APE1 enzymatic activity and increases the resistance of glioblastoma cells to the mono-alkylating agent temozolomide.

Kaur S, Ramdzan ZM, Guiot MC, Li L, Leduy L, Ramotar D, Sabri S, Abdulkarim B, Nepveu A.

Neuro Oncol. 2018 Mar 27;20(4):484-493. doi: 10.1093/neuonc/nox178.

18.

Highly Accurate Detection of Cancer In Situ with Intraoperative, Label-Free, Multimodal Optical Spectroscopy.

Jermyn M, Mercier J, Aubertin K, Desroches J, Urmey K, Karamchandiani J, Marple E, Guiot MC, Leblond F, Petrecca K.

Cancer Res. 2017 Jul 15;77(14):3942-3950. doi: 10.1158/0008-5472.CAN-17-0668. Epub 2017 Jun 28.

19.

Preferential susceptibility of limbic cortices to microstructural damage in temporal lobe epilepsy: A quantitative T1 mapping study.

Bernhardt BC, Fadaie F, Vos de Wael R, Hong SJ, Liu M, Guiot MC, Rudko DA, Bernasconi A, Bernasconi N.

Neuroimage. 2018 Nov 15;182:294-303. doi: 10.1016/j.neuroimage.2017.06.002. Epub 2017 Jun 3.

PMID:
28583883
20.

Benefit of re-operation and salvage therapies for recurrent glioblastoma multiforme: results from a single institution.

Azoulay M, Santos F, Shenouda G, Petrecca K, Oweida A, Guiot MC, Owen S, Panet-Raymond V, Souhami L, Abdulkarim BS.

J Neurooncol. 2017 May;132(3):419-426. doi: 10.1007/s11060-017-2383-2. Epub 2017 Apr 3.

PMID:
28374095
21.

Monoamine oxidase B inhibitor, selegiline, reduces 18F-THK5351 uptake in the human brain.

Ng KP, Pascoal TA, Mathotaarachchi S, Therriault J, Kang MS, Shin M, Guiot MC, Guo Q, Harada R, Comley RA, Massarweh G, Soucy JP, Okamura N, Gauthier S, Rosa-Neto P.

Alzheimers Res Ther. 2017 Mar 31;9(1):25. doi: 10.1186/s13195-017-0253-y.

22.

Multimodal MRI profiling of focal cortical dysplasia type II.

Hong SJ, Bernhardt BC, Caldairou B, Hall JA, Guiot MC, Schrader D, Bernasconi N, Bernasconi A.

Neurology. 2017 Feb 21;88(8):734-742. doi: 10.1212/WNL.0000000000003632. Epub 2017 Jan 27.

23.

Raman spectroscopy detects distant invasive brain cancer cells centimeters beyond MRI capability in humans.

Jermyn M, Desroches J, Mercier J, St-Arnaud K, Guiot MC, Leblond F, Petrecca K.

Biomed Opt Express. 2016 Nov 16;7(12):5129-5137. doi: 10.1364/BOE.7.005129. eCollection 2016 Dec 1.

24.

A Phase 2 Trial of Neoadjuvant Temozolomide Followed by Hypofractionated Accelerated Radiation Therapy With Concurrent and Adjuvant Temozolomide for Patients With Glioblastoma.

Shenouda G, Souhami L, Petrecca K, Owen S, Panet-Raymond V, Guiot MC, Corredor AG, Abdulkarim B.

Int J Radiat Oncol Biol Phys. 2017 Mar 1;97(3):487-494. doi: 10.1016/j.ijrobp.2016.11.006. Epub 2016 Nov 15.

PMID:
28011051
25.

A review of Raman spectroscopy advances with an emphasis on clinical translation challenges in oncology.

Jermyn M, Desroches J, Aubertin K, St-Arnaud K, Madore WJ, De Montigny E, Guiot MC, Trudel D, Wilson BC, Petrecca K, Leblond F.

Phys Med Biol. 2016 Dec 7;61(23):R370-R400. Epub 2016 Nov 2. Review.

PMID:
27804917
26.

Progression pattern and adverse events with bevacizumab in glioblastoma.

Mamo A, Baig A, Azam M, Rho YS, Sahebjam S, Muanza T, Owen S, Petrecca K, Guiot MC, Al-Shami J, Sharma R, Kavan P.

Curr Oncol. 2016 Oct;23(5):e468-e471. Epub 2016 Oct 25.

27.

The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway.

Carbonneau M, M Gagné L, Lalonde ME, Germain MA, Motorina A, Guiot MC, Secco B, Vincent EE, Tumber A, Hulea L, Bergeman J, Oppermann U, Jones RG, Laplante M, Topisirovic I, Petrecca K, Huot MÉ, Mallette FA.

Nat Commun. 2016 Sep 14;7:12700. doi: 10.1038/ncomms12700.

28.

Neural networks improve brain cancer detection with Raman spectroscopy in the presence of operating room light artifacts.

Jermyn M, Desroches J, Mercier J, Tremblay MA, St-Arnaud K, Guiot MC, Petrecca K, Leblond F.

J Biomed Opt. 2016 Sep 1;21(9):94002. doi: 10.1117/1.JBO.21.9.094002.

29.

Metabotropic Glutamate Receptor Type 5 (mGluR5) Cortical Abnormalities in Focal Cortical Dysplasia Identified In Vivo With [11C]ABP688 Positron-Emission Tomography (PET) Imaging.

DuBois JM, Rousset OG, Guiot MC, Hall JA, Reader AJ, Soucy JP, Rosa-Neto P, Kobayashi E.

Cereb Cortex. 2016 Oct 17;26(11):4170-4179. doi: 10.1093/cercor/bhw249.

30.

The spectrum of structural and functional imaging abnormalities in temporal lobe epilepsy.

Bernhardt BC, Bernasconi A, Liu M, Hong SJ, Caldairou B, Goubran M, Guiot MC, Hall J, Bernasconi N.

Ann Neurol. 2016 Jul;80(1):142-53. doi: 10.1002/ana.24691. Epub 2016 Jun 9.

PMID:
27228409
31.

Synchronous metastatic skull base chordoma to the breast: case report and literature review.

Shakir SI, Pelmus M, Florea A, Boileau JF, Guiot MC, Di Maio S, Muanza TM.

Curr Oncol. 2016 Apr;23(2):e154-7. doi: 10.3747/co.23.2896. Epub 2016 Apr 13.

32.

Differential transcriptional response profiles in human myeloid cell populations.

Healy LM, Perron G, Won SY, Rao VTS, Guiot MC, Moore C, Bar-Or A, Antel JP.

Clin Immunol. 2018 Apr;189:63-74. doi: 10.1016/j.clim.2016.04.006. Epub 2016 Apr 16.

PMID:
27094466
33.

Impaired RASGRF1/ERK-mediated GM-CSF response characterizes CARD9 deficiency in French-Canadians.

Gavino C, Hamel N, Zeng JB, Legault C, Guiot MC, Chankowsky J, Lejtenyi D, Lemire M, Alarie I, Dufresne S, Boursiquot JN, McIntosh F, Langelier M, Behr MA, Sheppard DC, Foulkes WD, Vinh DC.

J Allergy Clin Immunol. 2016 Apr;137(4):1178-1188.e7. doi: 10.1016/j.jaci.2015.09.016. Epub 2015 Oct 29.

PMID:
26521038
34.

The Fungal Exopolysaccharide Galactosaminogalactan Mediates Virulence by Enhancing Resistance to Neutrophil Extracellular Traps.

Lee MJ, Liu H, Barker BM, Snarr BD, Gravelat FN, Al Abdallah Q, Gavino C, Baistrocchi SR, Ostapska H, Xiao T, Ralph B, Solis NV, Lehoux M, Baptista SD, Thammahong A, Cerone RP, Kaminskyj SG, Guiot MC, Latgé JP, Fontaine T, Vinh DC, Filler SG, Sheppard DC.

PLoS Pathog. 2015 Oct 22;11(10):e1005187. doi: 10.1371/journal.ppat.1005187. eCollection 2015 Oct.

35.

Afatinib, an irreversible ErbB family blocker, with protracted temozolomide in recurrent glioblastoma: a case report.

Alshami J, Guiot MC, Owen S, Kavan P, Gibson N, Solca F, Cseh A, Reardon DA, Muanza T.

Oncotarget. 2015 Oct 20;6(32):34030-7. doi: 10.18632/oncotarget.5297.

36.

Characterization of a Raman spectroscopy probe system for intraoperative brain tissue classification.

Desroches J, Jermyn M, Mok K, Lemieux-Leduc C, Mercier J, St-Arnaud K, Urmey K, Guiot MC, Marple E, Petrecca K, Leblond F.

Biomed Opt Express. 2015 Jun 8;6(7):2380-97. doi: 10.1364/BOE.6.002380. eCollection 2015 Jul 1.

37.

Comparison of radiation regimens in the treatment of Glioblastoma multiforme: results from a single institution.

Azoulay M, Santos F, Souhami L, Panet-Raymond V, Petrecca K, Owen S, Guiot MC, Patyka M, Sabri S, Shenouda G, Abdulkarim B.

Radiat Oncol. 2015 Apr 26;10:106. doi: 10.1186/s13014-015-0396-6.

38.

Intraoperative brain cancer detection with Raman spectroscopy in humans.

Jermyn M, Mok K, Mercier J, Desroches J, Pichette J, Saint-Arnaud K, Bernstein L, Guiot MC, Petrecca K, Leblond F.

Sci Transl Med. 2015 Feb 11;7(274):274ra19. doi: 10.1126/scitranslmed.aaa2384.

PMID:
25673764
39.

Synchronous esthesioneuroblastoma and growth-hormone-secreting pituitary macroadenoma: combined open and endoscopic management.

Valdes CJ, Tewfik MA, Guiot MC, Di Maio S.

J Neurol Surg Rep. 2014 Dec;75(2):e194-9. doi: 10.1055/s-0034-1372472. Epub 2014 Jul 21.

40.

Giant petroclival primary intradural chordoma: case report and systematic review of the literature.

AlOtaibi F, Guiot MC, Muanza T, Di Maio S.

J Neurol Surg Rep. 2014 Aug;75(1):e160-9. doi: 10.1055/s-0034-1378157. Epub 2014 Jun 26.

41.

A novel mutation in the CSF1R gene causes a variable leukoencephalopathy with spheroids.

La Piana R, Webber A, Guiot MC, Del Pilar Cortes M, Brais B.

Neurogenetics. 2014 Oct;15(4):289-94. doi: 10.1007/s10048-014-0413-1. Epub 2014 Jul 12.

PMID:
25012610
42.

Dynamic reprogramming of signaling upon met inhibition reveals a mechanism of drug resistance in gastric cancer.

Lai AZ, Cory S, Zhao H, Gigoux M, Monast A, Guiot MC, Huang S, Tofigh A, Thompson C, Naujokas M, Marcus VA, Bertos N, Sehat B, Perera RM, Bell ES, Page BD, Gunning PT, Ferri LE, Hallett M, Park M.

Sci Signal. 2014 Apr 22;7(322):ra38. doi: 10.1126/scisignal.2004839.

PMID:
24757178
43.

Transcription factors FOXG1 and Groucho/TLE promote glioblastoma growth.

Verginelli F, Perin A, Dali R, Fung KH, Lo R, Longatti P, Guiot MC, Del Maestro RF, Rossi S, di Porzio U, Stechishin O, Weiss S, Stifani S.

Nat Commun. 2013;4:2956. doi: 10.1038/ncomms3956.

44.

Clinical Neuropathology practice guide 6-2013: morphology and an appropriate immunohistochemical screening panel aid in the identification of synovial sarcoma by neuropathologists.

Keith JL, Bilbao J, Croul S, Ang LC, Guiot MC, Rossiter J, Ghorab Z, Hawkins C, Karamchandani J.

Clin Neuropathol. 2013 Nov-Dec;32(6):461-70. doi: 10.5414/NP300685.

45.

Distinct increased metabotropic glutamate receptor type 5 (mGluR5) in temporal lobe epilepsy with and without hippocampal sclerosis.

Kandratavicius L, Rosa-Neto P, Monteiro MR, Guiot MC, Assirati JA Jr, Carlotti CG Jr, Kobayashi E, Leite JP.

Hippocampus. 2013 Dec;23(12):1212-30. doi: 10.1002/hipo.22160. Epub 2013 Jul 23.

46.

Does a positive Pittsburgh Compound B scan in a patient with dementia equal Alzheimer disease?

Ducharme S, Guiot MC, Nikelski J, Chertkow H.

JAMA Neurol. 2013 Jul;70(7):912-4. doi: 10.1001/jamaneurol.2013.420.

PMID:
23689280
47.

Lower motor neuron syndrome due to cauda equina hypertrophy with onion bulbs.

O'Ferrall EK, Gendron D, Guiot MC, Hall J, Sinnreich M.

Muscle Nerve. 2013 Aug;48(2):301-5. doi: 10.1002/mus.23816. Epub 2013 Jun 29.

PMID:
23424031
48.

An unusual mass at the abdominal site of a ventriculoperitoneal shunt.

Hébert-Blouin MN, Guiot MC, Hall JA.

Can J Neurol Sci. 2013 Mar;40(2):263-4. No abstract available.

PMID:
23419581
49.

Bevacizumab use for recurrent high-grade glioma at McGill University Hospital.

Sahebjam S, Garoufalis E, Guiot MC, Muanza T, Del Maestro R, Petrecca K, Sharma R, Kavan P.

Can J Neurol Sci. 2013 Mar;40(2):241-6.

PMID:
23419575
50.

Failure pattern following complete resection plus radiotherapy and temozolomide is at the resection margin in patients with glioblastoma.

Petrecca K, Guiot MC, Panet-Raymond V, Souhami L.

J Neurooncol. 2013 Jan;111(1):19-23. doi: 10.1007/s11060-012-0983-4. Epub 2012 Oct 10.

PMID:
23054563

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