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Items: 1 to 50 of 85

1.

Dual MAPK inhibition is an effective therapeutic strategy for a subset of class II BRAF mutant melanoma.

Dankner M, Lajoie M, Moldoveanu D, Nguyen TT, Savage P, Rajkumar S, Huang X, Lvova M, Protopopov A, Vuzman D, Hogg D, Park M, Guiot MC, Petrecca K, Mihalcioiu C, Watson IR, Siegel PM, Rose AAN.

Clin Cancer Res. 2018 Jun 14. pii: clincanres.3384.2017. doi: 10.1158/1078-0432.CCR-17-3384. [Epub ahead of print]

PMID:
29903896
2.

KIBRA (WWC1) Is a Metastasis Suppressor Gene Affected by Chromosome 5q Loss in Triple-Negative Breast Cancer.

Knight JF, Sung VYC, Kuzmin E, Couzens AL, de Verteuil DA, Ratcliffe CDH, Coelho PP, Johnson RM, Samavarchi-Tehrani P, Gruosso T, Smith HW, Lee W, Saleh SM, Zuo D, Zhao H, Guiot MC, Davis RR, Gregg JP, Moraes C, Gingras AC, Park M.

Cell Rep. 2018 Mar 20;22(12):3191-3205. doi: 10.1016/j.celrep.2018.02.095.

3.

A new method using Raman spectroscopy for in vivo targeted brain cancer tissue biopsy.

Desroches J, Jermyn M, Pinto M, Picot F, Tremblay MA, Obaid S, Marple E, Urmey K, Trudel D, Soulez G, Guiot MC, Wilson BC, Petrecca K, Leblond F.

Sci Rep. 2018 Jan 29;8(1):1792. doi: 10.1038/s41598-018-20233-3.

4.

Prognostic factors for progression in atypical meningioma.

Shakir SI, Souhami L, Petrecca K, Mansure JJ, Singh K, Panet-Raymond V, Shenouda G, Al-Odaini AA, Abdulkarim B, Guiot MC.

J Neurosurg. 2018 Jan 19:1-9. doi: 10.3171/2017.6.JNS17120. [Epub ahead of print]

PMID:
29350599
5.

Cavernous sinus syndrome associated with metastatic colorectal cancer and perineural spread along the trigeminal nerve.

Nassrallah G, Sun V, Guiot MC, Mikhail M, Arthurs B.

Am J Ophthalmol Case Rep. 2017 Mar 14;6:67-70. doi: 10.1016/j.ajoc.2016.11.011. eCollection 2017 Jun.

6.

Novel NAPRT specific antibody identifies small cell lung cancer and neuronal cancers as promising clinical indications for a NAMPT inhibitor/niacin co-administration strategy.

Cole J, Guiot MC, Gravel M, Bernier C, Shore GC, Roulston A.

Oncotarget. 2017 Sep 12;8(44):77846-77859. doi: 10.18632/oncotarget.20840. eCollection 2017 Sep 29.

7.

A Targetable EGFR-Dependent Tumor-Initiating Program in Breast Cancer.

Savage P, Blanchet-Cohen A, Revil T, Badescu D, Saleh SMI, Wang YC, Zuo D, Liu L, Bertos NR, Munoz-Ramos V, Basik M, Petrecca K, Asselah J, Meterissian S, Guiot MC, Omeroglu A, Kleinman CL, Park M, Ragoussis J.

Cell Rep. 2017 Oct 31;21(5):1140-1149. doi: 10.1016/j.celrep.2017.10.015.

8.

CUX1 stimulates APE1 enzymatic activity and increases the resistance of glioblastoma cells to the mono-alkylating agent temozolomide.

Kaur S, Ramdzan ZM, Guiot MC, Li L, Leduy L, Ramotar D, Sabri S, Abdulkarim B, Nepveu A.

Neuro Oncol. 2018 Mar 27;20(4):484-493. doi: 10.1093/neuonc/nox178.

PMID:
29036362
9.

Highly Accurate Detection of Cancer In Situ with Intraoperative, Label-Free, Multimodal Optical Spectroscopy.

Jermyn M, Mercier J, Aubertin K, Desroches J, Urmey K, Karamchandiani J, Marple E, Guiot MC, Leblond F, Petrecca K.

Cancer Res. 2017 Jul 15;77(14):3942-3950. doi: 10.1158/0008-5472.CAN-17-0668. Epub 2017 Jun 28.

10.

Preferential susceptibility of limbic cortices to microstructural damage in temporal lobe epilepsy: A quantitative T1 mapping study.

Bernhardt BC, Fadaie F, Vos de Wael R, Hong SJ, Liu M, Guiot MC, Rudko DA, Bernasconi A, Bernasconi N.

Neuroimage. 2017 Jun 3. pii: S1053-8119(17)30471-8. doi: 10.1016/j.neuroimage.2017.06.002. [Epub ahead of print]

PMID:
28583883
11.

Benefit of re-operation and salvage therapies for recurrent glioblastoma multiforme: results from a single institution.

Azoulay M, Santos F, Shenouda G, Petrecca K, Oweida A, Guiot MC, Owen S, Panet-Raymond V, Souhami L, Abdulkarim BS.

J Neurooncol. 2017 May;132(3):419-426. doi: 10.1007/s11060-017-2383-2. Epub 2017 Apr 3.

PMID:
28374095
12.

Monoamine oxidase B inhibitor, selegiline, reduces 18F-THK5351 uptake in the human brain.

Ng KP, Pascoal TA, Mathotaarachchi S, Therriault J, Kang MS, Shin M, Guiot MC, Guo Q, Harada R, Comley RA, Massarweh G, Soucy JP, Okamura N, Gauthier S, Rosa-Neto P.

Alzheimers Res Ther. 2017 Mar 31;9(1):25. doi: 10.1186/s13195-017-0253-y.

13.

Multimodal MRI profiling of focal cortical dysplasia type II.

Hong SJ, Bernhardt BC, Caldairou B, Hall JA, Guiot MC, Schrader D, Bernasconi N, Bernasconi A.

Neurology. 2017 Feb 21;88(8):734-742. doi: 10.1212/WNL.0000000000003632. Epub 2017 Jan 27.

14.

Raman spectroscopy detects distant invasive brain cancer cells centimeters beyond MRI capability in humans.

Jermyn M, Desroches J, Mercier J, St-Arnaud K, Guiot MC, Leblond F, Petrecca K.

Biomed Opt Express. 2016 Nov 16;7(12):5129-5137. doi: 10.1364/BOE.7.005129. eCollection 2016 Dec 1.

15.

A Phase 2 Trial of Neoadjuvant Temozolomide Followed by Hypofractionated Accelerated Radiation Therapy With Concurrent and Adjuvant Temozolomide for Patients With Glioblastoma.

Shenouda G, Souhami L, Petrecca K, Owen S, Panet-Raymond V, Guiot MC, Corredor AG, Abdulkarim B.

Int J Radiat Oncol Biol Phys. 2017 Mar 1;97(3):487-494. doi: 10.1016/j.ijrobp.2016.11.006. Epub 2016 Nov 15.

PMID:
28011051
16.

A review of Raman spectroscopy advances with an emphasis on clinical translation challenges in oncology.

Jermyn M, Desroches J, Aubertin K, St-Arnaud K, Madore WJ, De Montigny E, Guiot MC, Trudel D, Wilson BC, Petrecca K, Leblond F.

Phys Med Biol. 2016 Dec 7;61(23):R370-R400. Epub 2016 Nov 2. Review.

PMID:
27804917
17.

Progression pattern and adverse events with bevacizumab in glioblastoma.

Mamo A, Baig A, Azam M, Rho YS, Sahebjam S, Muanza T, Owen S, Petrecca K, Guiot MC, Al-Shami J, Sharma R, Kavan P.

Curr Oncol. 2016 Oct;23(5):e468-e471. Epub 2016 Oct 25.

18.

The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway.

Carbonneau M, M Gagné L, Lalonde ME, Germain MA, Motorina A, Guiot MC, Secco B, Vincent EE, Tumber A, Hulea L, Bergeman J, Oppermann U, Jones RG, Laplante M, Topisirovic I, Petrecca K, Huot MÉ, Mallette FA.

Nat Commun. 2016 Sep 14;7:12700. doi: 10.1038/ncomms12700.

19.

Neural networks improve brain cancer detection with Raman spectroscopy in the presence of operating room light artifacts.

Jermyn M, Desroches J, Mercier J, Tremblay MA, St-Arnaud K, Guiot MC, Petrecca K, Leblond F.

J Biomed Opt. 2016 Sep 1;21(9):94002. doi: 10.1117/1.JBO.21.9.094002.

PMID:
27604560
20.

Metabotropic Glutamate Receptor Type 5 (mGluR5) Cortical Abnormalities in Focal Cortical Dysplasia Identified In Vivo With [11C]ABP688 Positron-Emission Tomography (PET) Imaging.

DuBois JM, Rousset OG, Guiot MC, Hall JA, Reader AJ, Soucy JP, Rosa-Neto P, Kobayashi E.

Cereb Cortex. 2016 Oct 17;26(11):4170-4179. doi: 10.1093/cercor/bhw249.

21.

The spectrum of structural and functional imaging abnormalities in temporal lobe epilepsy.

Bernhardt BC, Bernasconi A, Liu M, Hong SJ, Caldairou B, Goubran M, Guiot MC, Hall J, Bernasconi N.

Ann Neurol. 2016 Jul;80(1):142-53. doi: 10.1002/ana.24691. Epub 2016 Jun 9.

PMID:
27228409
22.

Synchronous metastatic skull base chordoma to the breast: case report and literature review.

Shakir SI, Pelmus M, Florea A, Boileau JF, Guiot MC, Di Maio S, Muanza TM.

Curr Oncol. 2016 Apr;23(2):e154-7. doi: 10.3747/co.23.2896. Epub 2016 Apr 13.

23.

Differential transcriptional response profiles in human myeloid cell populations.

Healy LM, Perron G, Won SY, Rao VTS, Guiot MC, Moore C, Bar-Or A, Antel JP.

Clin Immunol. 2018 Apr;189:63-74. doi: 10.1016/j.clim.2016.04.006. Epub 2016 Apr 16.

PMID:
27094466
24.

Impaired RASGRF1/ERK-mediated GM-CSF response characterizes CARD9 deficiency in French-Canadians.

Gavino C, Hamel N, Zeng JB, Legault C, Guiot MC, Chankowsky J, Lejtenyi D, Lemire M, Alarie I, Dufresne S, Boursiquot JN, McIntosh F, Langelier M, Behr MA, Sheppard DC, Foulkes WD, Vinh DC.

J Allergy Clin Immunol. 2016 Apr;137(4):1178-1188.e7. doi: 10.1016/j.jaci.2015.09.016. Epub 2015 Oct 29.

PMID:
26521038
25.

The Fungal Exopolysaccharide Galactosaminogalactan Mediates Virulence by Enhancing Resistance to Neutrophil Extracellular Traps.

Lee MJ, Liu H, Barker BM, Snarr BD, Gravelat FN, Al Abdallah Q, Gavino C, Baistrocchi SR, Ostapska H, Xiao T, Ralph B, Solis NV, Lehoux M, Baptista SD, Thammahong A, Cerone RP, Kaminskyj SG, Guiot MC, Latgé JP, Fontaine T, Vinh DC, Filler SG, Sheppard DC.

PLoS Pathog. 2015 Oct 22;11(10):e1005187. doi: 10.1371/journal.ppat.1005187. eCollection 2015 Oct.

26.

Afatinib, an irreversible ErbB family blocker, with protracted temozolomide in recurrent glioblastoma: a case report.

Alshami J, Guiot MC, Owen S, Kavan P, Gibson N, Solca F, Cseh A, Reardon DA, Muanza T.

Oncotarget. 2015 Oct 20;6(32):34030-7. doi: 10.18632/oncotarget.5297.

27.

Characterization of a Raman spectroscopy probe system for intraoperative brain tissue classification.

Desroches J, Jermyn M, Mok K, Lemieux-Leduc C, Mercier J, St-Arnaud K, Urmey K, Guiot MC, Marple E, Petrecca K, Leblond F.

Biomed Opt Express. 2015 Jun 8;6(7):2380-97. doi: 10.1364/BOE.6.002380. eCollection 2015 Jul 1.

28.

Comparison of radiation regimens in the treatment of Glioblastoma multiforme: results from a single institution.

Azoulay M, Santos F, Souhami L, Panet-Raymond V, Petrecca K, Owen S, Guiot MC, Patyka M, Sabri S, Shenouda G, Abdulkarim B.

Radiat Oncol. 2015 Apr 26;10:106. doi: 10.1186/s13014-015-0396-6.

29.

Intraoperative brain cancer detection with Raman spectroscopy in humans.

Jermyn M, Mok K, Mercier J, Desroches J, Pichette J, Saint-Arnaud K, Bernstein L, Guiot MC, Petrecca K, Leblond F.

Sci Transl Med. 2015 Feb 11;7(274):274ra19. doi: 10.1126/scitranslmed.aaa2384.

PMID:
25673764
30.

Synchronous esthesioneuroblastoma and growth-hormone-secreting pituitary macroadenoma: combined open and endoscopic management.

Valdes CJ, Tewfik MA, Guiot MC, Di Maio S.

J Neurol Surg Rep. 2014 Dec;75(2):e194-9. doi: 10.1055/s-0034-1372472. Epub 2014 Jul 21.

31.

Giant petroclival primary intradural chordoma: case report and systematic review of the literature.

AlOtaibi F, Guiot MC, Muanza T, Di Maio S.

J Neurol Surg Rep. 2014 Aug;75(1):e160-9. doi: 10.1055/s-0034-1378157. Epub 2014 Jun 26.

32.

A novel mutation in the CSF1R gene causes a variable leukoencephalopathy with spheroids.

La Piana R, Webber A, Guiot MC, Del Pilar Cortes M, Brais B.

Neurogenetics. 2014 Oct;15(4):289-94. doi: 10.1007/s10048-014-0413-1. Epub 2014 Jul 12.

PMID:
25012610
33.

Dynamic reprogramming of signaling upon met inhibition reveals a mechanism of drug resistance in gastric cancer.

Lai AZ, Cory S, Zhao H, Gigoux M, Monast A, Guiot MC, Huang S, Tofigh A, Thompson C, Naujokas M, Marcus VA, Bertos N, Sehat B, Perera RM, Bell ES, Page BD, Gunning PT, Ferri LE, Hallett M, Park M.

Sci Signal. 2014 Apr 22;7(322):ra38. doi: 10.1126/scisignal.2004839.

PMID:
24757178
34.

Transcription factors FOXG1 and Groucho/TLE promote glioblastoma growth.

Verginelli F, Perin A, Dali R, Fung KH, Lo R, Longatti P, Guiot MC, Del Maestro RF, Rossi S, di Porzio U, Stechishin O, Weiss S, Stifani S.

Nat Commun. 2013;4:2956. doi: 10.1038/ncomms3956.

35.

Clinical Neuropathology practice guide 6-2013: morphology and an appropriate immunohistochemical screening panel aid in the identification of synovial sarcoma by neuropathologists.

Keith JL, Bilbao J, Croul S, Ang LC, Guiot MC, Rossiter J, Ghorab Z, Hawkins C, Karamchandani J.

Clin Neuropathol. 2013 Nov-Dec;32(6):461-70. doi: 10.5414/NP300685.

36.

Distinct increased metabotropic glutamate receptor type 5 (mGluR5) in temporal lobe epilepsy with and without hippocampal sclerosis.

Kandratavicius L, Rosa-Neto P, Monteiro MR, Guiot MC, Assirati JA Jr, Carlotti CG Jr, Kobayashi E, Leite JP.

Hippocampus. 2013 Dec;23(12):1212-30. doi: 10.1002/hipo.22160. Epub 2013 Jul 23.

37.

Does a positive Pittsburgh Compound B scan in a patient with dementia equal Alzheimer disease?

Ducharme S, Guiot MC, Nikelski J, Chertkow H.

JAMA Neurol. 2013 Jul;70(7):912-4. doi: 10.1001/jamaneurol.2013.420.

PMID:
23689280
38.

Lower motor neuron syndrome due to cauda equina hypertrophy with onion bulbs.

O'Ferrall EK, Gendron D, Guiot MC, Hall J, Sinnreich M.

Muscle Nerve. 2013 Aug;48(2):301-5. doi: 10.1002/mus.23816. Epub 2013 Jun 29.

PMID:
23424031
39.

An unusual mass at the abdominal site of a ventriculoperitoneal shunt.

Hébert-Blouin MN, Guiot MC, Hall JA.

Can J Neurol Sci. 2013 Mar;40(2):263-4. No abstract available.

PMID:
23419581
40.

Bevacizumab use for recurrent high-grade glioma at McGill University Hospital.

Sahebjam S, Garoufalis E, Guiot MC, Muanza T, Del Maestro R, Petrecca K, Sharma R, Kavan P.

Can J Neurol Sci. 2013 Mar;40(2):241-6.

PMID:
23419575
41.

Failure pattern following complete resection plus radiotherapy and temozolomide is at the resection margin in patients with glioblastoma.

Petrecca K, Guiot MC, Panet-Raymond V, Souhami L.

J Neurooncol. 2013 Jan;111(1):19-23. doi: 10.1007/s11060-012-0983-4. Epub 2012 Oct 10.

PMID:
23054563
42.

O6-Methylguanine-DNA methyltransferase is a novel negative effector of invasion in glioblastoma multiforme.

Chahal M, Abdulkarim B, Xu Y, Guiot MC, Easaw JC, Stifani N, Sabri S.

Mol Cancer Ther. 2012 Nov;11(11):2440-50. doi: 10.1158/1535-7163.MCT-11-0977. Epub 2012 Sep 17.

43.

Treatment of granulomatous amoebic encephalitis with voriconazole and miltefosine in an immunocompetent soldier.

Webster D, Umar I, Kolyvas G, Bilbao J, Guiot MC, Duplisea K, Qvarnstrom Y, Visvesvara GS.

Am J Trop Med Hyg. 2012 Oct;87(4):715-8. doi: 10.4269/ajtmh.2012.12-0100. Epub 2012 Aug 6. Erratum in: Am J Trop Med Hyg. 2012 Dec;87(6):1154. Umar, Imram [corrected to Umar, Imran].

44.

Comparison of polarization properties of human adult microglia and blood-derived macrophages.

Durafourt BA, Moore CS, Zammit DA, Johnson TA, Zaguia F, Guiot MC, Bar-Or A, Antel JP.

Glia. 2012 May;60(5):717-27. doi: 10.1002/glia.22298. Epub 2012 Jan 30.

PMID:
22290798
45.

Treatment of chordoma with imatinib complicated by intracranial hemorrhage: a case showing dissociation between biological effect and therapeutic outcome.

Mercier F, Guiot MC, Bojanowski MW.

J Neurooncol. 2012 Apr;107(2):435-7. doi: 10.1007/s11060-011-0767-2. Epub 2011 Nov 26. No abstract available.

PMID:
22120582
46.

Encephalopathy with neuroserpin inclusion bodies presenting as progressive myoclonus epilepsy and associated with a novel mutation in the Proteinase Inhibitor 12 gene.

Hagen MC, Murrell JR, Delisle MB, Andermann E, Andermann F, Guiot MC, Ghetti B.

Brain Pathol. 2011 Sep;21(5):575-82. doi: 10.1111/j.1750-3639.2011.00481.x. Epub 2011 Mar 24.

47.

A case of a spinal epidural capillary hemangioma: case report.

Hasan A, Guiot MC, Torres C, Marcoux J.

Neurosurgery. 2011 Mar;68(3):E850-3. doi: 10.1227/NEU.0b013e3182093320.

PMID:
21311280
48.

Double myxopapillary ependymomas of the filum terminale.

McLaughlin N, Guiot MC, Jacques L.

Can J Neurol Sci. 2011 Jan;38(1):151-4. No abstract available.

PMID:
21156449
49.

Preponderance of sonic hedgehog pathway activation characterizes adult medulloblastoma.

Al-Halabi H, Nantel A, Klekner A, Guiot MC, Albrecht S, Hauser P, Garami M, Bognar L, Kavan P, Gerges N, Shirinian M, Roberge D, Muanza T, Jabado N.

Acta Neuropathol. 2011 Feb;121(2):229-39. doi: 10.1007/s00401-010-0780-0. Epub 2010 Nov 24.

PMID:
21107850
50.

Scedosporium cerebral abscesses after extra-corporeal membrane oxygenation.

Al-Jehani H, Guiot MC, Torres C, Marcoux J.

Can J Neurol Sci. 2010 Sep;37(5):671-6. Review.

PMID:
21059516

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