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Items: 1 to 50 of 103

1.

Use of Crowd Innovation to Develop an Artificial Intelligence-Based Solution for Radiation Therapy Targeting.

Mak RH, Endres MG, Paik JH, Sergeev RA, Aerts H, Williams CL, Lakhani KR, Guinan EC.

JAMA Oncol. 2019 May 1;5(5):654-661. doi: 10.1001/jamaoncol.2019.0159.

2.

Alloanergization Method for Inducing Allospecific Hyporesponsiveness in PBMC Exposed to Allostimulation In Vitro in the Context of Costimulatory Molecule Blockade.

Barbon CM, Janec KJ, Kelner RH, Norton JE, Guinan EC.

Methods Mol Biol. 2019;1899:103-118. doi: 10.1007/978-1-4939-8938-6_8.

PMID:
30649768
3.

Combination therapy with atorvastatin and celecoxib delays tumor formation in a Fanconi anemia mouse model.

Zhang QS, Deater M, Phan N, Marcogliese A, Major A, Guinan EC, Grompe M.

Pediatr Blood Cancer. 2019 Jan;66(1):e27460. doi: 10.1002/pbc.27460. Epub 2018 Sep 25.

PMID:
30255556
4.

Toward a more scientific science.

Azoulay P, Graff-Zivin J, Uzzi B, Wang D, Williams H, Evans JA, Jin GZ, Lu SF, Jones BF, Börner K, Lakhani KR, Boudreau KJ, Guinan EC.

Science. 2018 Sep 21;361(6408):1194-1197. doi: 10.1126/science.aav2484. No abstract available.

PMID:
30237341
5.

The Open Translational Science in Schizophrenia (OPTICS) project: an open-science project bringing together Janssen clinical trial and NIMH data.

Wilcox MA, Savitz AJ, Addington AM, Gray GS, Guinan EC, Jackson JW, Lehner T, Normand SL, Ranu H, Senthil G, Spertus J, Valeri L, Ross JS.

NPJ Schizophr. 2018 Jun 27;4(1):14. doi: 10.1038/s41537-018-0055-7. Review.

6.

Infusion of Alloanergized Donor Lymphocytes after CD34-selected Haploidentical Myeloablative Hematopoietic Stem Cell Transplantation.

Davies JK, Brennan LL, Wingard JR, Cogle CR, Kapoor N, Shah AJ, Dey BR, Spitzer TR, de Lima M, Cooper LJ, Thall PF, Champlin RE, Nadler LM, Guinan EC.

Clin Cancer Res. 2018 Sep 1;24(17):4098-4109. doi: 10.1158/1078-0432.CCR-18-0449. Epub 2018 May 16.

7.

rBPI21 (Opebacan) Promotes Rapid Trilineage Hematopoietic Recovery in a Murine Model of High-Dose Total Body Irradiation.

Janec KJ, Yuan H, Norton JE, Kelner RH, Hirt CK, Betensky RA, Guinan EC.

Am J Hematol. 2018 May 11. doi: 10.1002/ajh.25136. [Epub ahead of print]

8.

Three sides to a story: Child, parent, and nurse perspectives on the child's experience during hematopoietic stem cell transplantation.

Ullrich CK, Rodday AM, Bingen KM, Kupst MJ, Patel SK, Syrjala KL, Harris LL, Recklitis CJ, Chang G, Guinan EC, Terrin N, Tighiouart H, Phipps S, Parsons SK.

Cancer. 2017 Aug 15;123(16):3159-3166. doi: 10.1002/cncr.30723. Epub 2017 Apr 7.

9.

Pre-existing invasive fungal infection is not a contraindication for allogeneic HSCT for patients with hematologic malignancies: a CIBMTR study.

Maziarz RT, Brazauskas R, Chen M, McLeod AA, Martino R, Wingard JR, Aljurf M, Battiwalla M, Dvorak CC, Geroge B, Guinan EC, Hale GA, Lazarus HM, Lee JW, Liesveld JL, Ramanathan M, Reddy V, Savani BN, Smith FO, Strasfeld L, Taplitz RA, Ustun C, Boeckh MJ, Gea-Banacloche J, Lindemans CA, Auletta JJ, Riches ML.

Bone Marrow Transplant. 2017 Feb;52(2):270-278. doi: 10.1038/bmt.2016.259. Epub 2016 Dec 19.

10.

Looking Across and Looking Beyond the Knowledge Frontier: Intellectual Distance, Novelty, and Resource Allocation in Science.

Boudreau KJ, Guinan EC, Lakhani KR, Riedl C.

Manage Sci. 2016 Oct;62(10):2765-2783. Epub 2016 Jan 8.

11.

Phase 3 trial of defibrotide for the treatment of severe veno-occlusive disease and multi-organ failure.

Richardson PG, Riches ML, Kernan NA, Brochstein JA, Mineishi S, Termuhlen AM, Arai S, Grupp SA, Guinan EC, Martin PL, Steinbach G, Krishnan A, Nemecek ER, Giralt S, Rodriguez T, Duerst R, Doyle J, Antin JH, Smith A, Lehmann L, Champlin R, Gillio A, Bajwa R, D'Agostino RB Sr, Massaro J, Warren D, Miloslavsky M, Hume RL, Iacobelli M, Nejadnik B, Hannah AL, Soiffer RJ.

Blood. 2016 Mar 31;127(13):1656-65. doi: 10.1182/blood-2015-10-676924. Epub 2016 Jan 29.

12.

Ex Vivo Costimulatory Blockade to Generate Regulatory T Cells From Patients Awaiting Kidney Transplantation.

Guinan EC, Cole GA, Wylie WH, Kelner RH, Janec KJ, Yuan H, Oppatt J, Brennan LL, Turka LA, Markmann J.

Am J Transplant. 2016 Jul;16(7):2187-95. doi: 10.1111/ajt.13725. Epub 2016 Mar 11.

13.

Parent Outlook: How Parents View the Road Ahead as They Embark on Hematopoietic Stem Cell Transplantation for Their Child.

Ullrich CK, Rodday AM, Bingen K, Kupst MJ, Patel SK, Syrjala KL, Harris LL, Recklitis CJ, Schwartz L, Davies S, Guinan EC, Chang G, Wolfe J, Parsons SK.

Biol Blood Marrow Transplant. 2016 Jan;22(1):104-11. doi: 10.1016/j.bbmt.2015.08.040. Epub 2015 Sep 5.

14.

The impact of pediatric blood and marrow transplant on parents: introduction of the parent impact scale.

Heinze KE, Rodday AM, Nolan MT, Bingen K, Kupst MJ, Patel SK, Syrjala K, Harris L, Recklitis C, Schwartz L, Davies S, Guinan EC, Noll R, Chang G, Parsons SK.

Health Qual Life Outcomes. 2015 Apr 9;13:46. doi: 10.1186/s12955-015-0240-6.

15.

Bone loss and vitamin D deficiency in children undergoing hematopoietic cell transplantation.

Bechard LJ, Gordon C, Feldman HA, Venick R, Gura K, Guinan EC, Duggan C.

Pediatr Blood Cancer. 2015 Apr;62(4):687-92. doi: 10.1002/pbc.25370. Epub 2015 Jan 28.

16.

Changing factors associated with parent activation after pediatric hematopoietic stem cell transplant.

Pennarola BW, Rodday AM, Bingen K, Schwartz LA, Patel SK, Syrjala KL, Mayer DK, Ratichek SJ, Guinan EC, Kupst MJ, Hibbard JH, Parsons SK.

Support Care Cancer. 2015 Jul;23(7):1997-2006. doi: 10.1007/s00520-014-2544-1. Epub 2014 Dec 18.

17.

Aplastic anemia in adolescents and young adults.

DeZern AE, Guinan EC.

Acta Haematol. 2014;132(3-4):331-9. doi: 10.1159/000360209. Epub 2014 Sep 10. Review.

18.

Serum citrulline as a biomarker of gastrointestinal function during hematopoietic cell transplantation in children.

Gosselin KB, Feldman HA, Sonis AL, Bechard LJ, Kellogg MD, Gura K, Venick R, Gordon CM, Guinan EC, Duggan C.

J Pediatr Gastroenterol Nutr. 2014 Jun;58(6):709-14. doi: 10.1097/MPG.0000000000000335.

19.

Alloanergization of human T cells results in expansion of alloantigen-specific CD8(+) CD28(-) suppressor cells.

Barbon CM, Davies JK, Voskertchian A, Kelner RH, Brennan LL, Nadler LM, Guinan EC.

Am J Transplant. 2014 Feb;14(2):305-18. doi: 10.1111/ajt.12575. Epub 2014 Jan 10.

20.

Identification of single nucleotide polymorphisms in hematopoietic cell transplant patients affecting early recognition of, and response to, endotoxin.

Guinan EC, Palmer CD, Mancuso CJ, Brennan L, Stoler-Barak L, Kalish LA, Suter EE, Gallington LC, Huhtelin DP, Mansilla M, Schumann RR, Murray JC, Weiss J, Levy O.

Innate Immun. 2014 Oct;20(7):697-711. doi: 10.1177/1753425913505122. Epub 2013 Oct 9.

21.

Allogeneic hematopoietic cell transplantation for fanconi anemia in patients with pretransplantation cytogenetic abnormalities, myelodysplastic syndrome, or acute leukemia.

Ayas M, Saber W, Davies SM, Harris RE, Hale GA, Socie G, LeRademacher J, Thakar M, Deeg HJ, Al-Seraihy A, Battiwalla M, Camitta BM, Olsson R, Bajwa RS, Bonfim CM, Pasquini R, Macmillan ML, George B, Copelan EA, Wirk B, Al Jefri A, Fasth AL, Guinan EC, Horn BN, Lewis VA, Slavin S, Stepensky P, Bierings M, Gale RP.

J Clin Oncol. 2013 May 1;31(13):1669-76. doi: 10.1200/JCO.2012.45.9719. Epub 2013 Apr 1.

22.

Prize-based contests can provide solutions to computational biology problems.

Lakhani KR, Boudreau KJ, Loh PR, Backstrom L, Baldwin C, Lonstein E, Lydon M, MacCormack A, Arnaout RA, Guinan EC.

Nat Biotechnol. 2013 Feb;31(2):108-11. doi: 10.1038/nbt.2495. No abstract available.

23.

A young adult with aplastic anemia and gray hair.

Guinan EC, Agarwal S.

Clin Chem. 2013 Jan;59(1):47-50. doi: 10.1373/clinchem.2012.187237. No abstract available.

24.

Effect of weight on outcomes of children undergoing hematopoietic cell transplantation.

Myers LC, Sun P, Brennan LL, London WB, Guinan EC.

Pediatr Hematol Oncol. 2013 Mar;30(2):116-30. doi: 10.3109/08880018.2012.743201. Epub 2012 Nov 28. Review.

PMID:
23189973
25.

Ex vivo alloanergization with belatacept: a strategy to selectively modulate alloresponses after transplantation.

Davies JK, Barbon CM, Voskertchian A, Nadler LM, Guinan EC.

Cell Transplant. 2012;21(9):2047-61. doi: 10.3727/096368912X637479. Epub 2012 Apr 10.

PMID:
22507909
26.

Attenuation of resting energy expenditure following hematopoietic SCT in children.

Bechard LJ, Feldman HA, Venick R, Gura K, Gordon C, Sonis A, Mehta N, Guinan EC, Duggan C.

Bone Marrow Transplant. 2012 Oct;47(10):1301-6. doi: 10.1038/bmt.2012.19. Epub 2012 Feb 20.

27.

Effect of titrated parenteral nutrition on body composition after allogeneic hematopoietic stem cell transplantation in children: a double-blind, randomized, multicenter trial.

Sharma TS, Bechard LJ, Feldman HA, Venick R, Gura K, Gordon CM, Sonis A, Guinan EC, Duggan C.

Am J Clin Nutr. 2012 Feb;95(2):342-51. doi: 10.3945/ajcn.111.026005. Epub 2011 Dec 28.

28.

Factors associated with parental activation in pediatric hematopoietic stem cell transplant.

Pennarola BW, Rodday AM, Mayer DK, Ratichek SJ, Davies SM, Syrjala KL, Patel S, Bingen K, Kupst MJ, Schwartz L, Guinan EC, Hibbard JH, Parsons SK; HSCT-CHESS Study.

Med Care Res Rev. 2012 Apr;69(2):194-214. doi: 10.1177/1077558711431460. Epub 2011 Dec 26.

29.

Therapy for aplastic anemia.

DeZern AE, Guinan EC.

Hematology Am Soc Hematol Educ Program. 2011;2011:82-3. doi: 10.1182/asheducation-2011.1.82.

30.

Diagnosis and management of aplastic anemia.

Guinan EC.

Hematology Am Soc Hematol Educ Program. 2011;2011:76-81. doi: 10.1182/asheducation-2011.1.76. Review.

PMID:
22160015
31.

Bactericidal/permeability-increasing protein (rBPI21) and fluoroquinolone mitigate radiation-induced bone marrow aplasia and death.

Guinan EC, Barbon CM, Kalish LA, Parmar K, Kutok J, Mancuso CJ, Stoler-Barak L, Suter EE, Russell JD, Palmer CD, Gallington LC, Voskertchian A, Vergilio JA, Cole G, Zhu K, D'Andrea A, Soiffer R, Weiss JP, Levy O.

Sci Transl Med. 2011 Nov 23;3(110):110ra118. doi: 10.1126/scitranslmed.3003126.

32.

Deficient expression of bactericidal/permeability-increasing protein in immunocompromised hosts: translational potential of replacement therapy.

Palmer CD, Guinan EC, Levy O.

Biochem Soc Trans. 2011 Aug;39(4):994-9. doi: 10.1042/BST0390994.

PMID:
21787336
33.

17(R)-Resolvin D1 differentially regulates TLR4-mediated responses of primary human macrophages to purified LPS and live E. coli.

Palmer CD, Mancuso CJ, Weiss JP, Serhan CN, Guinan EC, Levy O.

J Leukoc Biol. 2011 Sep;90(3):459-70. doi: 10.1189/jlb.0311145. Epub 2011 Jun 7.

34.

Sweet syndrome in patients with Fanconi anaemia: association with extracutaneous manifestations and progression of haematological disease.

Giulino L, Guinan EC, Gillio AP, Drachtman RA, Teruya-Feldstein J, Boulad F.

Br J Haematol. 2011 Jul;154(2):278-81. doi: 10.1111/j.1365-2141.2011.08604.x. Epub 2011 Apr 19. No abstract available.

PMID:
21501135
35.

Induction of alloantigen-specific anergy in human peripheral blood mononuclear cells by alloantigen stimulation with co-stimulatory signal blockade.

Davies JK, Barbon CM, Voskertchian AR, Nadler LM, Guinan EC.

J Vis Exp. 2011 Mar 14;(49). pii: 2673. doi: 10.3791/2673.

36.

Combining CD19 redirection and alloanergization to generate tumor-specific human T cells for allogeneic cell therapy of B-cell malignancies.

Davies JK, Singh H, Huls H, Yuk D, Lee DA, Kebriaei P, Champlin RE, Nadler LM, Guinan EC, Cooper LJ.

Cancer Res. 2010 May 15;70(10):3915-24. doi: 10.1158/0008-5472.CAN-09-3845. Epub 2010 Apr 27.

37.

Expansion of allospecific regulatory T cells after anergized, mismatched bone marrow transplantation.

Davies JK, Nadler LM, Guinan EC.

Sci Transl Med. 2009 Oct 7;1(1):1ra3. doi: 10.1126/scitranslmed.3000153.

38.

Outcome of hematopoietic stem cell transplant in children with congenital heart disease.

Guinan EC, Hewett EK, Domaney NM, Margossian R.

Pediatr Transplant. 2011 Feb;15(1):75-80. doi: 10.1111/j.1399-3046.2010.01317.x.

PMID:
20345610
39.

Defibrotide for the treatment of severe hepatic veno-occlusive disease and multiorgan failure after stem cell transplantation: a multicenter, randomized, dose-finding trial.

Richardson PG, Soiffer RJ, Antin JH, Uno H, Jin Z, Kurtzberg J, Martin PL, Steinbach G, Murray KF, Vogelsang GB, Chen AR, Krishnan A, Kernan NA, Avigan DE, Spitzer TR, Shulman HM, Di Salvo DN, Revta C, Warren D, Momtaz P, Bradwin G, Wei LJ, Iacobelli M, McDonald GB, Guinan EC.

Biol Blood Marrow Transplant. 2010 Jul;16(7):1005-17. doi: 10.1016/j.bbmt.2010.02.009. Epub 2010 Feb 16.

40.

A multi-center, randomized, controlled trial of parenteral nutrition titrated to resting energy expenditure in children undergoing hematopoietic stem cell transplantation ("PNTREE"): rationale and design.

Bechard LJ, Feldman HA, Gordon C, Gura K, Sonis A, Leung K, Venick R, Guinan EC, Duggan C.

Contemp Clin Trials. 2010 Mar;31(2):157-64. doi: 10.1016/j.cct.2009.12.002. Epub 2010 Jan 3.

41.

Acquired aplastic anemia in childhood.

Guinan EC.

Hematol Oncol Clin North Am. 2009 Apr;23(2):171-91. doi: 10.1016/j.hoc.2009.01.011. Review.

PMID:
19327578
42.

Induction of alloanergy in human donor T cells without loss of pathogen or tumor immunity.

Davies JK, Yuk D, Nadler LM, Guinan EC.

Transplantation. 2008 Sep 27;86(6):854-64. doi: 10.1097/TP.0b013e3181861b6c. Erratum in: Transplantation. 2012 Jun 15;93(11):e44. Dosage error in article text.

43.

Results of the Cord Blood Transplantation Study (COBLT): clinical outcomes of unrelated donor umbilical cord blood transplantation in pediatric patients with hematologic malignancies.

Kurtzberg J, Prasad VK, Carter SL, Wagner JE, Baxter-Lowe LA, Wall D, Kapoor N, Guinan EC, Feig SA, Wagner EL, Kernan NA; COBLT Steering Committee.

Blood. 2008 Nov 15;112(10):4318-27. doi: 10.1182/blood-2007-06-098020. Epub 2008 Aug 21.

44.

Outcome of alloanergized haploidentical bone marrow transplantation after ex vivo costimulatory blockade: results of 2 phase 1 studies.

Davies JK, Gribben JG, Brennan LL, Yuk D, Nadler LM, Guinan EC.

Blood. 2008 Sep 15;112(6):2232-41. doi: 10.1182/blood-2008-03-143636. Epub 2008 Jul 10.

45.

Weekly measurements accurately represent trends in resting energy expenditure in children undergoing hematopoietic stem cell transplantation.

Duro D, Bechard LJ, Feldman HA, Klykov A, O'Leary A, Guinan EC, Duggan C.

JPEN J Parenter Enteral Nutr. 2008 Jul-Aug;32(4):427-32. doi: 10.1177/0148607108319804.

46.

Prognostic factors in the resumption of oral dietary intake after allogeneic hematopoietic stem cell transplantation (HSCT) in children.

Bechard LJ, Guinan EC, Feldman HA, Tang V, Duggan C.

JPEN J Parenter Enteral Nutr. 2007 Jul-Aug;31(4):295-301.

47.

An update on the management of severe idiopathic aplastic anaemia in children.

Davies JK, Guinan EC.

Br J Haematol. 2007 Feb;136(4):549-64. Review.

PMID:
17214739
48.

A novel pattern of transaminase elevation associated with autologous transplant for neuroblastoma.

Guinan EC, Kalish LA, Berry WS, McDaniel S, Lehmann LE, Diller LR.

Pediatr Transplant. 2006 Sep;10(6):669-76.

PMID:
16911489
49.

Aplastic anemia: management of pediatric patients.

Guinan EC.

Hematology Am Soc Hematol Educ Program. 2005:104-9.

PMID:
16304366
50.

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