Sort by
Items per page

Send to

Choose Destination

Search results

Items: 39


Generating Robust and Informative Nonclinical In Vitro and In Vivo Bacterial Infection Model Efficacy Data To Support Translation to Humans.

Bulitta JB, Hope WW, Eakin AE, Guina T, Tam VH, Louie A, Drusano GL, Hoover JL.

Antimicrob Agents Chemother. 2019 Apr 25;63(5). pii: e02307-18. doi: 10.1128/AAC.02307-18. Print 2019 May. Review.


Considerations for Dose Selection and Clinical Pharmacokinetics/Pharmacodynamics for the Development of Antibacterial Agents.

Rizk ML, Bhavnani SM, Drusano G, Dane A, Eakin AE, Guina T, Jang SH, Tomayko JF, Wang J, Zhuang L, Lodise TP.

Antimicrob Agents Chemother. 2019 Apr 25;63(5). pii: e02309-18. doi: 10.1128/AAC.02309-18. Print 2019 May. Review.


The Cynomolgus Macaque Natural History Model of Pneumonic Tularemia for Predicting Clinical Efficacy Under the Animal Rule.

Guina T, Lanning LL, Omland KS, Williams MS, Wolfraim LA, Heyse SP, Houchens CR, Sanz P, Hewitt JA.

Front Cell Infect Microbiol. 2018 Apr 4;8:99. doi: 10.3389/fcimb.2018.00099. eCollection 2018.


The role of p38 MAPK in the induction of intestinal inflammation by dietary oxysterols: modulation by wine phenolics.

Guina T, Deiana M, Calfapietra S, Cabboi B, Maina M, Tuberoso CI, Leonarduzzi G, Gamba P, Gargiulo S, Testa G, Poli G, Biasi F.

Food Funct. 2015 Apr;6(4):1218-28. doi: 10.1039/c4fo01116c.


Inflammatory and redox reactions in colorectal carcinogenesis.

Guina T, Biasi F, Calfapietra S, Nano M, Poli G.

Ann N Y Acad Sci. 2015 Mar;1340:95-103. doi: 10.1111/nyas.12734. Epub 2015 Feb 27. Review.


Wine consumption and intestinal redox homeostasis.

Biasi F, Deiana M, Guina T, Gamba P, Leonarduzzi G, Poli G.

Redox Biol. 2014 Jun 18;2:795-802. doi: 10.1016/j.redox.2014.06.008. eCollection 2014. Review.


Loading into nanoparticles improves quercetin's efficacy in preventing neuroinflammation induced by oxysterols.

Testa G, Gamba P, Badilli U, Gargiulo S, Maina M, Guina T, Calfapietra S, Biasi F, Cavalli R, Poli G, Leonarduzzi G.

PLoS One. 2014 May 6;9(5):e96795. doi: 10.1371/journal.pone.0096795. eCollection 2014.


Evaluation of immunogenicity and efficacy of anthrax vaccine adsorbed for postexposure prophylaxis.

Ionin B, Hopkins RJ, Pleune B, Sivko GS, Reid FM, Clement KH, Rudge TL Jr, Stark GV, Innes A, Sari S, Guina T, Howard C, Smith J, Swoboda ML, Vert-Wong E, Johnson V, Nabors GS, Skiadopoulos MH.

Clin Vaccine Immunol. 2013 Jul;20(7):1016-26. doi: 10.1128/CVI.00099-13. Epub 2013 May 8.


Phenolic compounds present in Sardinian wine extracts protect against the production of inflammatory cytokines induced by oxysterols in CaCo-2 human enterocyte-like cells.

Biasi F, Guina T, Maina M, Cabboi B, Deiana M, Tuberoso CI, Calfapietra S, Chiarpotto E, Sottero B, Gamba P, Gargiulo S, Brunetto V, Testa G, Dessì MA, Poli G, Leonarduzzi G.

Biochem Pharmacol. 2013 Jul 1;86(1):138-45. doi: 10.1016/j.bcp.2013.03.024. Epub 2013 Apr 9.


Molecular signaling involved in oxysterol-induced β₁-integrin over-expression in human macrophages.

Gargiulo S, Gamba P, Testa G, Sottero B, Maina M, Guina T, Biasi F, Poli G, Leonarduzzi G.

Int J Mol Sci. 2012 Nov 5;13(11):14278-93. doi: 10.3390/ijms131114278.


Evidence of cell damage induced by major components of a diet-compatible mixture of oxysterols in human colon cancer CaCo-2 cell line.

Biasi F, Chiarpotto E, Sottero B, Maina M, Mascia C, Guina T, Gamba P, Gargiulo S, Testa G, Leonarduzzi G, Poli G.

Biochimie. 2013 Mar;95(3):632-40. doi: 10.1016/j.biochi.2012.10.011. Epub 2012 Oct 22.


Progressive increase of matrix metalloprotease-9 and interleukin-8 serum levels during carcinogenic process in human colorectal tract.

Biasi F, Guina T, Maina M, Nano M, Falcone A, Aroasio E, Saracco GM, Papotti M, Leonarduzzi G, Poli G.

PLoS One. 2012;7(7):e41839. doi: 10.1371/journal.pone.0041839. Epub 2012 Jul 25.


Fragmentation-free LC-MS can identify hundreds of proteins.

Bochet P, Rügheimer F, Guina T, Brooks P, Goodlett D, Clote P, Schwikowski B.

Proteomics. 2011 Jan;11(1):22-32. doi: 10.1002/pmic.200900765. Epub 2010 Dec 6.


Haematological, biochemical and bone density parameters in vegetarians and non-vegetarians.

Sambol SZ, Stimac D, Orlić ZC, Guina T.

West Indian Med J. 2009 Dec;58(6):512-7.


Identification, cloning, expression, and purification of Francisella lpp3: an immunogenic lipoprotein.

Parra MC, Shaffer SA, Hajjar AM, Gallis BM, Hager A, Goodlett DR, Guina T, Miller S, Collins CM.

Microbiol Res. 2010 Sep 20;165(7):531-45. doi: 10.1016/j.micres.2009.11.004. Epub 2009 Dec 14.


Treatment of severe psoriasis with infliximab: report of two cases.

Peternel S, Prpić-Massari L, Guina T, Novak S, Brajac I, Kastelan M.

Acta Dermatovenerol Croat. 2009;17(3):204-6.


Effects of nutritional support in patients with colorectal cancer during chemotherapy.

Dintinjana RD, Guina T, Krznarić Z, Radić M, Dintinjana M.

Coll Antropol. 2008 Sep;32(3):737-40.


Medical and psychological parameters in overweight and obese persons seeking treatment.

Guina T, Pokrajac-Bulian A, Tkalcić M, Basić Marković N, Crncević Orlić Z, Corić S, Stimac D.

Coll Antropol. 2008 Jun;32(2):601-6.


Nutritional and pharmacologic support in patients with pancreatic cancer.

Dobrila Dintinjana R, Guina T, Krznarić Z.

Coll Antropol. 2008 Jun;32(2):505-8.


MglA and Igl proteins contribute to the modulation of Francisella tularensis live vaccine strain-containing phagosomes in murine macrophages.

Bönquist L, Lindgren H, Golovliov I, Guina T, Sjöstedt A.

Infect Immun. 2008 Aug;76(8):3502-10. doi: 10.1128/IAI.00226-08. Epub 2008 May 12.


Determination and comparison of the Francisella tularensis subsp.novicida U112 proteome to other bacterial proteomes.

Rohmer L, Guina T, Chen J, Gallis B, Taylor GK, Shaffer SA, Miller SI, Brittnacher MJ, Goodlett DR.

J Proteome Res. 2008 May;7(5):2016-24. doi: 10.1021/pr700760z. Epub 2008 Apr 2.


PhoPQ-mediated regulation produces a more robust permeability barrier in the outer membrane of Salmonella enterica serovar typhimurium.

Murata T, Tseng W, Guina T, Miller SI, Nikaido H.

J Bacteriol. 2007 Oct;189(20):7213-22. Epub 2007 Aug 10.


MglA regulates Francisella tularensis subsp. novicida (Francisella novicida) response to starvation and oxidative stress.

Guina T, Radulovic D, Bahrami AJ, Bolton DL, Rohmer L, Jones-Isaac KA, Chen J, Gallagher LA, Gallis B, Ryu S, Taylor GK, Brittnacher MJ, Manoil C, Goodlett DR.

J Bacteriol. 2007 Sep;189(18):6580-6. Epub 2007 Jul 20.


Comparison of Francisella tularensis genomes reveals evolutionary events associated with the emergence of human pathogenic strains.

Rohmer L, Fong C, Abmayr S, Wasnick M, Larson Freeman TJ, Radey M, Guina T, Svensson K, Hayden HS, Jacobs M, Gallagher LA, Manoil C, Ernst RK, Drees B, Buckley D, Haugen E, Bovee D, Zhou Y, Chang J, Levy R, Lim R, Gillett W, Guenthener D, Kang A, Shaffer SA, Taylor G, Chen J, Gallis B, D'Argenio DA, Forsman M, Olson MV, Goodlett DR, Kaul R, Miller SI, Brittnacher MJ.

Genome Biol. 2007;8(6):R102.


Type II secretion and type IV pili of Francisella.

Forsberg A, Guina T.

Ann N Y Acad Sci. 2007 Jun;1105:187-201. Epub 2007 Apr 13. Review.


An extreme case of neurofibromatosis type 1.

Stimac D, Novak S, Guina T.

Wien Klin Wochenschr. 2007;119(3-4):90. No abstract available.


Type IV pili-mediated secretion modulates Francisella virulence.

Hager AJ, Bolton DL, Pelletier MR, Brittnacher MJ, Gallagher LA, Kaul R, Skerrett SJ, Miller SI, Guina T.

Mol Microbiol. 2006 Oct;62(1):227-37.


The Pseudomonas aeruginosa proteome during anaerobic growth.

Wu M, Guina T, Brittnacher M, Nguyen H, Eng J, Miller SI.

J Bacteriol. 2005 Dec;187(23):8185-90.


Mouse paneth cell secretory responses to cell surface glycolipids of virulent and attenuated pathogenic bacteria.

Tanabe H, Ayabe T, Bainbridge B, Guina T, Ernst RK, Darveau RP, Miller SI, Ouellette AJ.

Infect Immun. 2005 Apr;73(4):2312-20.


Activity of Staphylococcus epidermidis phenol-soluble modulin peptides expressed in Staphylococcus carnosus.

Otto M, O'Mahoney DS, Guina T, Klebanoff SJ.

J Infect Dis. 2004 Aug 15;190(4):748-55. Epub 2004 Jul 19.


Bacterial vesicle formation as a mechanism of protein transfer to animals.

Miller SI, Bader M, Guina T.

Cell. 2003 Oct 3;115(1):2-3.


Proteomic analysis of Pseudomonas aeruginosa grown under magnesium limitation.

Guina T, Wu M, Miller SI, Purvine SO, Yi EC, Eng J, Goodlett DR, Aebersold R, Ernst RK, Lee KA.

J Am Soc Mass Spectrom. 2003 Jul;14(7):742-51.


Quantitative proteomic analysis indicates increased synthesis of a quinolone by Pseudomonas aeruginosa isolates from cystic fibrosis airways.

Guina T, Purvine SO, Yi EC, Eng J, Goodlett DR, Aebersold R, Miller SI.

Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2771-6. Epub 2003 Feb 24.


Salmonella typhimurium outer membrane remodeling: role in resistance to host innate immunity.

Ernst RK, Guina T, Miller SI.

Microbes Infect. 2001 Nov-Dec;3(14-15):1327-34. Review.


Transfer of palmitate from phospholipids to lipid A in outer membranes of gram-negative bacteria.

Bishop RE, Gibbons HS, Guina T, Trent MS, Miller SI, Raetz CR.

EMBO J. 2000 Oct 2;19(19):5071-80.


How intracellular bacteria survive: surface modifications that promote resistance to host innate immune responses.

Ernst RK, Guina T, Miller SI.

J Infect Dis. 1999 Mar;179 Suppl 2:S326-30. Review.


Sequence and phylogenetic analysis of the Borrelia burgdorferi secA gene.

Guina T, Helfet-Hilliker D, Ramamurthy V, Oliver D.

Biochim Biophys Acta. 1998 Apr 22;1371(1):24-30.


Supplemental Content

Support Center