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Items: 1 to 50 of 193

1.

The Place of PET to Assess New Therapeutic Effectiveness in Neurodegenerative Diseases.

Dupont AC, Largeau B, Guilloteau D, Santiago Ribeiro MJ, Arlicot N.

Contrast Media Mol Imaging. 2018 May 17;2018:7043578. doi: 10.1155/2018/7043578. eCollection 2018. Review.

2.

Amyloid PET Positivity in Different Primary Progressive Aphasia Phenotypes.

Beaufils E, Vercouillie J, Vierron E, Cottier JP, Camus V, Mondon K, Guilloteau D, Hommet C, Ribeiro MJ.

Clin Nucl Med. 2018 Apr;43(4):e103-e108. doi: 10.1097/RLU.0000000000002018.

PMID:
29504965
3.

TSPO PET Imaging: From Microglial Activation to Peripheral Sterile Inflammatory Diseases?

Largeau B, Dupont AC, Guilloteau D, Santiago-Ribeiro MJ, Arlicot N.

Contrast Media Mol Imaging. 2017 Sep 25;2017:6592139. doi: 10.1155/2017/6592139. eCollection 2017. Review.

4.

The Variability of Translocator Protein Signal in Brain and Blood of Genotyped Healthy Humans Using In Vivo 123I-CLINDE SPECT Imaging: A Test-Retest Study.

Feng L, Jensen P, Thomsen G, Dyssegaard A, Svarer C, Knudsen LV, Møller K, Thomsen C, Mikkelsen JD, Guilloteau D, Knudsen GM, Pinborg LH.

J Nucl Med. 2017 Jun;58(6):989-995. doi: 10.2967/jnumed.116.183202. Epub 2016 Nov 10.

5.

Molecular Targets for PET Imaging of Activated Microglia: The Current Situation and Future Expectations.

Tronel C, Largeau B, Santiago Ribeiro MJ, Guilloteau D, Dupont AC, Arlicot N.

Int J Mol Sci. 2017 Apr 11;18(4). pii: E802. doi: 10.3390/ijms18040802. Review.

6.

Translocator Protein-18 kDa (TSPO) Positron Emission Tomography (PET) Imaging and Its Clinical Impact in Neurodegenerative Diseases.

Dupont AC, Largeau B, Santiago Ribeiro MJ, Guilloteau D, Tronel C, Arlicot N.

Int J Mol Sci. 2017 Apr 7;18(4). pii: E785. doi: 10.3390/ijms18040785. Review.

7.

Erratum to "Validation of amino-acids measurement in dried blood spot by FIA-MS/MS for PKU management" [Clin. Biochem. 49 (2016) 1047-1050].

Bruno C, Dufour-Rainfray D, Patin F, Vourc'h P, Guilloteau D, Maillot F, Labarthe F, Tardieu M, Andres CR, Emond P, Blasco H.

Clin Biochem. 2017 Jun;50(9):546. doi: 10.1016/j.clinbiochem.2017.03.023. Epub 2017 May 2. No abstract available.

PMID:
28366684
8.

Editorial: Innovative Radiopharmaceuticals in Oncology and Neurology.

Barbet J, Arlicot N, Gaugler MH, Chérel M, Guilloteau D, Kraeber-Bodéré F.

Front Med (Lausanne). 2017 Jan 11;3:74. doi: 10.3389/fmed.2016.00074. eCollection 2016. No abstract available.

9.

68Ga 'vacuum elution approach' for direct radiolabelling of DOTA-conjugated and NODAGA-conjugated peptides.

Ben Azzouna R, Leygnac S, Al-Shoukr F, Rouzet F, Guilloteau D, Le Guludec D.

Nucl Med Commun. 2017 Jan;38(1):51-56.

PMID:
27824725
10.

Subjective cognitive decline in cognitively normal elders from the community or from a memory clinic: Differential affective and imaging correlates.

Perrotin A, La Joie R, de La Sayette V, Barré L, Mézenge F, Mutlu J, Guilloteau D, Egret S, Eustache F, Chételat G.

Alzheimers Dement. 2017 May;13(5):550-560. doi: 10.1016/j.jalz.2016.08.011. Epub 2016 Sep 28.

PMID:
27693187
11.

Validation of amino-acids measurement in dried blood spot by FIA-MS/MS for PKU management.

Bruno C, Dufour-Rainfray D, Patin F, Vourc'h P, Guilloteau D, Maillot F, Labarthe F, Tardieu M, Andres CR, Emond P, Blasco H.

Clin Biochem. 2016 Sep;49(13-14):1047-50. doi: 10.1016/j.clinbiochem.2016.07.008. Epub 2016 Jul 21. Erratum in: Clin Biochem. 2017 Jun;50(9):546. Vourch, P [corrected to Vourc'h , P].

PMID:
27450222
12.

Detection of Neuroinflammation in a Rat Model of Subarachnoid Hemorrhage Using [18F]DPA-714 PET Imaging.

Thomas C, Vercouillie J, Doméné A, Tauber C, Kassiou M, Guilloteau D, Destrieux C, Sérrière S, Chalon S.

Mol Imaging. 2016 Apr 26;15. pii: 1536012116639189. doi: 10.1177/1536012116639189. Print 2016.

13.

Design of α7 nicotinic acetylcholine receptor ligands using the (het)Aryl-1,2,3-triazole core: Synthesis, in vitro evaluation and SAR studies.

Ouach A, Pin F, Bertrand E, Vercouillie J, Gulhan Z, Mothes C, Deloye JB, Guilloteau D, Suzenet F, Chalon S, Routier S.

Eur J Med Chem. 2016 Jan 1;107:153-64. doi: 10.1016/j.ejmech.2015.11.001. Epub 2015 Nov 10.

PMID:
26580980
14.

Assessment of the Protection of Dopaminergic Neurons by an α7 Nicotinic Receptor Agonist, PHA 543613 Using [(18)F]LBT-999 in a Parkinson's Disease Rat Model.

Sérrière S, Doméné A, Vercouillie J, Mothes C, Bodard S, Rodrigues N, Guilloteau D, Routier S, Page G, Chalon S.

Front Med (Lausanne). 2015 Sep 2;2:61. doi: 10.3389/fmed.2015.00061. eCollection 2015.

15.

[11C]MADAM Used as a Model for Understanding the Radiometabolism of Diphenyl Sulfide Radioligands for Positron Emission Tomography (PET).

Gourand F, Amini N, Jia Z, Stone-Elander S, Guilloteau D, Barré L, Halldin C.

PLoS One. 2015 Sep 14;10(9):e0137160. doi: 10.1371/journal.pone.0137160. eCollection 2015.

16.

PET tracers for imaging brain α7 nicotinic receptors: an update.

Chalon S, Vercouillie J, Guilloteau D, Suzenet F, Routier S.

Chem Commun (Camb). 2015 Oct 14;51(80):14826-31. doi: 10.1039/c5cc04536c.

PMID:
26359819
17.

Precuneus and Cingulate Cortex Atrophy and Hypometabolism in Patients with Alzheimer's Disease and Mild Cognitive Impairment: MRI and (18)F-FDG PET Quantitative Analysis Using FreeSurfer.

Bailly M, Destrieux C, Hommet C, Mondon K, Cottier JP, Beaufils E, Vierron E, Vercouillie J, Ibazizene M, Voisin T, Payoux P, Barré L, Camus V, Guilloteau D, Ribeiro MJ.

Biomed Res Int. 2015;2015:583931. doi: 10.1155/2015/583931. Epub 2015 Jun 17.

18.

A new (68)Ga anionic concentration and purification method for automated synthesis of [(68)Ga]-DOTA or NODAGA conjugated peptides in high radiochemical purity.

Ben Azzouna R, Alshoukr F, Leygnac S, Guez A, Gonzalez W, Rousseaux O, Guilloteau D, Le Guludec D.

J Labelled Comp Radiopharm. 2015 Aug;58(10):403-10. doi: 10.1002/jlcr.3316. Epub 2015 Aug 4.

PMID:
26242879
19.

TSPO Imaging in Glioblastoma Multiforme: A Direct Comparison Between 123I-CLINDE SPECT, 18F-FET PET, and Gadolinium-Enhanced MR Imaging.

Jensen P, Feng L, Law I, Svarer C, Knudsen GM, Mikkelsen JD, de Nijs R, Larsen VA, Dyssegaard A, Thomsen G, Fischer W, Guilloteau D, Pinborg LH.

J Nucl Med. 2015 Sep;56(9):1386-90. doi: 10.2967/jnumed.115.158998. Epub 2015 Jul 16.

20.

Amyloid load and translocator protein 18 kDa in APPswePS1-dE9 mice: a longitudinal study.

Sérrière S, Tauber C, Vercouillie J, Mothes C, Pruckner C, Guilloteau D, Kassiou M, Doméné A, Garreau L, Page G, Chalon S.

Neurobiol Aging. 2015 Apr;36(4):1639-1652. doi: 10.1016/j.neurobiolaging.2014.11.023. Epub 2015 Jan 16.

PMID:
25680265
21.

[Mass spectrometry for steroid assays].

Dufour-Rainfray D, Moal V, Cloix L, Mathieu E, Gauchez AS, Brossaud J, Corcuff JB, Fraissinet F, Collet C, Boux de Casson F, Guilloteau D, Emond P, Reynier P.

Ann Biol Clin (Paris). 2015 Jan-Feb;73(1):70-8. doi: 10.1684/abc.2014.0988. Review. French.

22.

18F-FDG and 18F-florbetapir PET in clinical practice: regional analysis in mild cognitive impairment and Alzheimer disease.

Bailly M, Ribeiro MJ, Vercouillie J, Hommet C, Gissot V, Camus V, Guilloteau D.

Clin Nucl Med. 2015 Feb;40(2):e111-6. doi: 10.1097/RLU.0000000000000666.

PMID:
25549345
23.

The Pattern of Brain Amyloid Load in Posterior Cortical Atrophy Using (18)F-AV45: Is Amyloid the Principal Actor in the Disease?

Beaufils E, Ribeiro MJ, Vierron E, Vercouillie J, Dufour-Rainfray D, Cottier JP, Camus V, Mondon K, Guilloteau D, Hommet C.

Dement Geriatr Cogn Dis Extra. 2014 Nov 11;4(3):431-41. doi: 10.1159/000363761. eCollection 2014 Sep.

24.

Variational segmentation of vector-valued images with gradient vector flow.

Jaouen V, González P, Stute S, Guilloteau D, Chalon S, Buvat I, Tauber C.

IEEE Trans Image Process. 2014 Nov;23(11):4773-85. doi: 10.1109/TIP.2014.2353854. Epub 2014 Sep 4.

PMID:
25203991
25.

Could (18) F-DPA-714 PET imaging be interesting to use in the early post-stroke period?

Ribeiro MJ, Vercouillie J, Debiais S, Cottier JP, Bonnaud I, Camus V, Banister S, Kassiou M, Arlicot N, Guilloteau D.

EJNMMI Res. 2014 Jun 6;4:28. doi: 10.1186/s13550-014-0028-4. eCollection 2014.

26.

Design of α7 nicotinic acetylcholine receptor ligands in quinuclidine, tropane and quinazoline series. Chemistry, molecular modeling, radiochemistry, in vitro and in rats evaluations of a [(18)F] quinuclidine derivative.

Pin F, Vercouillie J, Ouach A, Mavel S, Gulhan Z, Chicheri G, Jarry C, Massip S, Deloye JB, Guilloteau D, Suzenet F, Chalon S, Routier S.

Eur J Med Chem. 2014 Jul 23;82:214-24. doi: 10.1016/j.ejmech.2014.04.057. Epub 2014 May 9.

PMID:
24904968
27.

PiB-Conjugated, Metal-Based Imaging Probes: Multimodal Approaches for the Visualization of β-Amyloid Plaques.

Martins AF, Morfin JF, Kubíčková A, Kubíček V, Buron F, Suzenet F, Salerno M, Lazar AN, Duyckaerts C, Arlicot N, Guilloteau D, Geraldes CF, Tóth E.

ACS Med Chem Lett. 2013 Apr 15;4(5):436-40. doi: 10.1021/ml400042w. eCollection 2013 May 9.

28.

A radiometabolite study of the serotonin transporter PET radioligand [(11)C]MADAM.

Gourand F, Emond P, Bergström JP, Takano A, Gulyás B, Guilloteau D, Barré L, Halldin C.

Nucl Med Biol. 2014 Jul;41(6):501-6. doi: 10.1016/j.nucmedbio.2014.03.022. Epub 2014 Apr 2.

PMID:
24857865
29.

Translocator protein (18 kDa) mapping with [125I]-CLINDE in the quinolinic acid rat model of excitotoxicity: a longitudinal comparison with microglial activation, astrogliosis, and neuronal death.

Arlicot N, Tronel C, Bodard S, Garreau L, de la Crompe B, Vandevelde I, Guilloteau D, Antier D, Chalon S.

Mol Imaging. 2014;13:4-11.

PMID:
24622813
30.

In vivo PET quantification of the dopamine transporter in rat brain with [¹⁸F]LBT-999.

Sérrière S, Tauber C, Vercouillie J, Guilloteau D, Deloye JB, Garreau L, Galineau L, Chalon S.

Nucl Med Biol. 2014 Jan;41(1):106-13. doi: 10.1016/j.nucmedbio.2013.09.007. Epub 2013 Oct 8.

PMID:
24210285
31.

Total protein level in cerebrospinal fluid is stable in elderly adults.

Dufour-Rainfray D, Beaufils E, Vourc'h P, Vierron E, Mereghetti L, Gendrot C, Hommet C, Andres CR, Guilloteau D, Mondon K.

J Am Geriatr Soc. 2013 Oct;61(10):1819-21. doi: 10.1111/jgs.12489. No abstract available.

PMID:
24117297
32.

Neuroinflammation and β amyloid deposition in Alzheimer's disease: in vivo quantification with molecular imaging.

Hommet C, Mondon K, Camus V, Ribeiro MJ, Beaufils E, Arlicot N, Corcia P, Paccalin M, Minier F, Gosselin T, Page G, Guilloteau D, Chalon S.

Dement Geriatr Cogn Disord. 2014;37(1-2):1-18. doi: 10.1159/000354363. Epub 2013 Oct 1. Review.

33.

Brain [18F]FDDNP binding and glucose metabolism in advanced elderly healthy subjects and Alzheimer's disease patients.

Tauber C, Beaufils E, Hommet C, Ribeiro MJ, Vercouillie J, Vierron E, Mondon K, Cottier JP, Gissot V, Guilloteau D, Camus V.

J Alzheimers Dis. 2013;36(2):311-20. doi: 10.3233/JAD-122068.

PMID:
23609763
34.

Molecular imaging of microglial activation in amyotrophic lateral sclerosis.

Corcia P, Tauber C, Vercoullie J, Arlicot N, Prunier C, Praline J, Nicolas G, Venel Y, Hommet C, Baulieu JL, Cottier JP, Roussel C, Kassiou M, Guilloteau D, Ribeiro MJ.

PLoS One. 2012;7(12):e52941. doi: 10.1371/journal.pone.0052941. Epub 2012 Dec 31.

35.

Region-specific hierarchy between atrophy, hypometabolism, and β-amyloid (Aβ) load in Alzheimer's disease dementia.

La Joie R, Perrotin A, Barré L, Hommet C, Mézenge F, Ibazizene M, Camus V, Abbas A, Landeau B, Guilloteau D, de La Sayette V, Eustache F, Desgranges B, Chételat G.

J Neurosci. 2012 Nov 14;32(46):16265-73. doi: 10.1523/JNEUROSCI.2170-12.2012.

36.

Progressive supranuclear palsy: in vivo SPECT imaging of presynaptic vesicular acetylcholine transporter with [123I]-iodobenzovesamicol.

Mazère J, Meissner WG, Mayo W, Sibon I, Lamare F, Guilloteau D, Tison F, Allard M.

Radiology. 2012 Nov;265(2):537-43. doi: 10.1148/radiol.12112650. Epub 2012 Sep 25.

PMID:
23012462
37.

Confirmation of the amyloidogenic process in posterior cortical atrophy: value of the Aβ42/Aβ40 ratio.

Beaufils E, Dufour-Rainfray D, Hommet C, Brault F, Cottier JP, Ribeiro MJ, Mondon K, Guilloteau D.

J Alzheimers Dis. 2013;33(3):775-80. doi: 10.3233/JAD-2012-121267.

PMID:
22986776
38.

Effects of translocator protein (18 kDa) ligands on microglial activation and neuronal death in the quinolinic-acid-injected rat striatum.

Leaver KR, Reynolds A, Bodard S, Guilloteau D, Chalon S, Kassiou M.

ACS Chem Neurosci. 2012 Feb 15;3(2):114-9. doi: 10.1021/cn200099e. Epub 2011 Dec 12.

39.

Longitudinal and parallel monitoring of neuroinflammation and neurodegeneration in a 6-hydroxydopamine rat model of Parkinson's disease.

Maia S, Arlicot N, Vierron E, Bodard S, Vergote J, Guilloteau D, Chalon S.

Synapse. 2012 Jul;66(7):573-83. doi: 10.1002/syn.21543. Epub 2012 Feb 15.

PMID:
22337286
40.

QSAR study and synthesis of new phenyltropanes as ligands of the dopamine transporter (DAT).

Mavel S, Mincheva Z, Méheux N, Carcenac Y, Guilloteau D, Abarbri M, Emond P.

Bioorg Med Chem. 2012 Feb 15;20(4):1388-95. doi: 10.1016/j.bmc.2012.01.014. Epub 2012 Jan 18.

PMID:
22300887
41.

PET imaging with [18F]AV-45 in an APP/PS1-21 murine model of amyloid plaque deposition.

Poisnel G, Dhilly M, Moustié O, Delamare J, Abbas A, Guilloteau D, Barré L.

Neurobiol Aging. 2012 Nov;33(11):2561-71. doi: 10.1016/j.neurobiolaging.2011.12.024. Epub 2012 Jan 24.

PMID:
22277262
42.

Using PET with 18F-AV-45 (florbetapir) to quantify brain amyloid load in a clinical environment.

Camus V, Payoux P, Barré L, Desgranges B, Voisin T, Tauber C, La Joie R, Tafani M, Hommet C, Chételat G, Mondon K, de La Sayette V, Cottier JP, Beaufils E, Ribeiro MJ, Gissot V, Vierron E, Vercouillie J, Vellas B, Eustache F, Guilloteau D.

Eur J Nucl Med Mol Imaging. 2012 Apr;39(4):621-31. doi: 10.1007/s00259-011-2021-8. Epub 2012 Jan 18.

43.

Initial evaluation in healthy humans of [18F]DPA-714, a potential PET biomarker for neuroinflammation.

Arlicot N, Vercouillie J, Ribeiro MJ, Tauber C, Venel Y, Baulieu JL, Maia S, Corcia P, Stabin MG, Reynolds A, Kassiou M, Guilloteau D.

Nucl Med Biol. 2012 May;39(4):570-8. doi: 10.1016/j.nucmedbio.2011.10.012. Epub 2011 Dec 14.

PMID:
22172392
44.

Evaluation of a 3D local multiresolution algorithm for the correction of partial volume effects in positron emission tomography.

Le Pogam A, Hatt M, Descourt P, Boussion N, Tsoumpas C, Turkheimer FE, Prunier-Aesch C, Baulieu JL, Guilloteau D, Visvikis D.

Med Phys. 2011 Sep;38(9):4920-3. doi: 10.1118/1.3608907.

45.

Spatio-temporal diffusion of dynamic PET images.

Tauber C, Stute S, Chau M, Spiteri P, Chalon S, Guilloteau D, Buvat I.

Phys Med Biol. 2011 Oct 21;56(20):6583-96. doi: 10.1088/0031-9155/56/20/004. Epub 2011 Sep 21.

PMID:
21937774
46.

Imaging of the striatal and extrastriatal dopamine transporter with (18)F-LBT-999: quantification, biodistribution, and radiation dosimetry in nonhuman primates.

Varrone A, Stepanov V, Nakao R, Tóth M, Gulyás B, Emond P, Deloye JB, Vercouillie J, Stabin MG, Jonsson C, Guilloteau D, Halldin C.

J Nucl Med. 2011 Aug;52(8):1313-21. doi: 10.2967/jnumed.111.089953. Epub 2011 Jul 15.

47.

Fetal exposure to teratogens: evidence of genes involved in autism.

Dufour-Rainfray D, Vourc'h P, Tourlet S, Guilloteau D, Chalon S, Andres CR.

Neurosci Biobehav Rev. 2011 Apr;35(5):1254-65. doi: 10.1016/j.neubiorev.2010.12.013. Epub 2010 Dec 30. Review.

PMID:
21195109
48.

Kinetic analysis and quantification of the dopamine transporter in the nonhuman primate brain with 11C-PE2I and 18F-FE-PE2I.

Varrone A, Tóth M, Steiger C, Takano A, Guilloteau D, Ichise M, Gulyás B, Halldin C.

J Nucl Med. 2011 Jan;52(1):132-9. doi: 10.2967/jnumed.110.077651.

49.

3D QSAR study, synthesis, and in vitro evaluation of (+)-5-FBVM as potential PET radioligand for the vesicular acetylcholine transporter (VAChT).

Kovac M, Mavel S, Deuther-Conrad W, Méheux N, Glöckner J, Wenzel B, Anderluh M, Brust P, Guilloteau D, Emond P.

Bioorg Med Chem. 2010 Nov 1;18(21):7659-67. doi: 10.1016/j.bmc.2010.08.028. Epub 2010 Aug 17.

PMID:
20889347
50.

Detection and quantification of remote microglial activation in rodent models of focal ischaemia using the TSPO radioligand CLINDE.

Arlicot N, Petit E, Katsifis A, Toutain J, Divoux D, Bodard S, Roussel S, Guilloteau D, Bernaudin M, Chalon S.

Eur J Nucl Med Mol Imaging. 2010 Dec;37(12):2371-80. doi: 10.1007/s00259-010-1598-7. Epub 2010 Sep 3.

PMID:
20814674

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