Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 14

1.

MI130004, a Novel Antibody-Drug Conjugate Combining Trastuzumab with a Molecule of Marine Origin, Shows Outstanding In Vivo Activity against HER2-Expressing Tumors.

Avilés P, Domínguez JM, Guillén MJ, Muñoz-Alonso MJ, Mateo C, Rodriguez-Acebes R, Molina-Guijarro JM, Francesch A, Martínez-Leal JF, Munt S, Galmarini CM, Cuevas C.

Mol Cancer Ther. 2018 Apr;17(4):786-794. doi: 10.1158/1535-7163.MCT-17-0795. Epub 2018 Feb 13.

PMID:
29440297
2.

Improved pharmacokinetic profile of lipophilic anti-cancer drugs using ανβ3-targeted polyurethane-polyurea nanoparticles.

Rocas P, Fernández Y, García-Aranda N, Foradada L, Calvo P, Avilés P, Guillén MJ, Schwartz S Jr, Rocas J, Albericio F, Abasolo I.

Nanomedicine. 2018 Feb;14(2):257-267. doi: 10.1016/j.nano.2017.10.009. Epub 2017 Nov 7.

PMID:
29127040
3.

Lurbinectedin induces depletion of tumor-associated macrophages, an essential component of its in vivo synergism with gemcitabine, in pancreatic adenocarcinoma mouse models.

Céspedes MV, Guillén MJ, López-Casas PP, Sarno F, Gallardo A, Álamo P, Cuevas C, Hidalgo M, Galmarini CM, Allavena P, Avilés P, Mangues R.

Dis Model Mech. 2016 Dec 1;9(12):1461-1471. Epub 2016 Oct 20.

4.

Development of a liquid chromatography/tandem mass spectrometry assay for the quantification of PM01183 (lurbinectedin), a novel antineoplastic agent, in mouse, rat, dog, Cynomolgus monkey and mini-pig plasma.

Pernice T, Bishop AG, Guillen MJ, Cuevas C, Aviles P.

J Pharm Biomed Anal. 2016 May 10;123:37-41. doi: 10.1016/j.jpba.2016.01.043. Epub 2016 Jan 21.

PMID:
26871278
5.

Enhanced in vivo therapeutic efficacy of plitidepsin-loaded nanocapsules decorated with a new poly-aminoacid-PEG derivative.

Lollo G, Hervella P, Calvo P, Avilés P, Guillén MJ, Garcia-Fuentes M, Alonso MJ, Torres D.

Int J Pharm. 2015 Apr 10;483(1-2):212-9. doi: 10.1016/j.ijpharm.2015.02.028. Epub 2015 Feb 11.

PMID:
25681727
6.

Nano-encapsulation of plitidepsin: in vivo pharmacokinetics, biodistribution, and efficacy in a renal xenograft tumor model.

Oliveira H, Thevenot J, Garanger E, Ibarboure E, Calvo P, Aviles P, Guillen MJ, Lecommandoux S.

Pharm Res. 2014 Apr;31(4):983-91. doi: 10.1007/s11095-013-1220-3. Epub 2013 Nov 28.

PMID:
24287622
7.

A new potential nano-oncological therapy based on polyamino acid nanocapsules.

Gonzalo T, Lollo G, Garcia-Fuentes M, Torres D, Correa J, Riguera R, Fernandez-Megia E, Calvo P, Avilés P, Guillén MJ, Alonso MJ.

J Control Release. 2013 Jul 10;169(1-2):10-6.

PMID:
23591661
8.

Lurbinectedin (PM01183), a new DNA minor groove binder, inhibits growth of orthotopic primary graft of cisplatin-resistant epithelial ovarian cancer.

Vidal A, Muñoz C, Guillén MJ, Moretó J, Puertas S, Martínez-Iniesta M, Figueras A, Padullés L, García-Rodriguez FJ, Berdiel-Acer M, Pujana MA, Salazar R, Gil-Martin M, Martí L, Ponce J, Molleví DG, Capella G, Condom E, Viñals F, Huertas D, Cuevas C, Esteller M, Avilés P, Villanueva A.

Clin Cancer Res. 2012 Oct 1;18(19):5399-411. doi: 10.1158/1078-0432.CCR-12-1513. Epub 2012 Aug 15.

9.

Development of a liquid chromatography/tandem mass spectrometry assay for the quantification of PM02734, a novel antineoplastic agent, in dog plasma.

Yin J, Aviles P, Lee W, Ly C, Guillen MJ, Munt S, Cuevas C, Faircloth G.

Rapid Commun Mass Spectrom. 2006;20(18):2735-40.

PMID:
16921565
10.

Quantitative analysis of Variolin analog (PM01218) in mouse and rat plasma by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry.

Yin J, Aviles P, Ly C, Lee W, Guillen MJ, Munt S, Cuevas C, Faircloth G.

J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Mar 7;832(2):268-73. Epub 2006 Feb 21.

PMID:
16497567
11.

Development of a liquid chromatography/tandem mass spectrometry assay for the quantification of PM00104, a novel antineoplastic agent, in mouse, rat, dog, and human plasma.

Yin J, Aviles P, Lee W, Ly C, Guillen MJ, Munt S, Cuevas C, Faircloth G.

Rapid Commun Mass Spectrom. 2005;19(5):689-95.

PMID:
15702485
12.

Validation of a sensitive assay for thiocoraline in mouse plasma using liquid chromatography-tandem mass spectrometry.

Yin J, Aviles P, Lee W, Ly C, Guillen MJ, Calvo P, Manzanares I, Faircloth G.

J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Aug 25;794(1):89-98.

PMID:
12888201
13.

Animal pharmacokinetics and interspecies scaling of sordarin derivatives following intravenous administration.

Aviles P, Pateman A, San Roman R, Guillén MJ, Gómez De Las Heras F, Gargallo-Viola D.

Antimicrob Agents Chemother. 2001 Oct;45(10):2787-92.

14.

Supplemental Content

Loading ...
Support Center