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Items: 9


Platelet-Specific Deletion of Cyclooxygenase-1 Ameliorates Dextran Sulfate Sodium-Induced Colitis in Mice.

Sacco A, Bruno A, Contursi A, Dovizio M, Tacconelli S, Ricciotti E, Guillem-Llobat P, Salvatore T, Di Francesco L, Fullone R, Ballerini P, Arena V, Alberti S, Liu G, Gong Y, Sgambato A, Patrono C, FitzGerald GA, Yu Y, Patrignani P.

J Pharmacol Exp Ther. 2019 Sep;370(3):416-426. doi: 10.1124/jpet.119.259382. Epub 2019 Jun 27.


Aspirin prevents colorectal cancer metastasis in mice by splitting the crosstalk between platelets and tumor cells.

Guillem-Llobat P, Dovizio M, Bruno A, Ricciotti E, Cufino V, Sacco A, Grande R, Alberti S, Arena V, Cirillo M, Patrono C, FitzGerald GA, Steinhilber D, Sgambato A, Patrignani P.

Oncotarget. 2016 May 31;7(22):32462-77. doi: 10.18632/oncotarget.8655.


Role of COX-2-derived PGE2 on vascular stiffness and function in hypertension.

Avendaño MS, Martínez-Revelles S, Aguado A, Simões MR, González-Amor M, Palacios R, Guillem-Llobat P, Vassallo DV, Vila L, García-Puig J, Beltrán LM, Alonso MJ, Cachofeiro MV, Salaices M, Briones AM.

Br J Pharmacol. 2016 May;173(9):1541-55. doi: 10.1111/bph.13457. Epub 2016 Mar 21.


Novel insights into the regulation of cyclooxygenase-2 expression by platelet-cancer cell cross-talk.

Dovizio M, Alberti S, Sacco A, Guillem-Llobat P, Schiavone S, Maier TJ, Steinhilber D, Patrignani P.

Biochem Soc Trans. 2015 Aug;43(4):707-14. doi: 10.1042/BST20140322. Epub 2015 Aug 3. Review.


Dysregulation of gene expression in human fetal endothelial cells from gestational diabetes in response to TGF-β1.

Marcantoni E, Dovizio M, O'Gaora P, Di Francesco L, Bendaya I, Schiavone S, Trenti A, Guillem-Llobat P, Zambon A, Nardelli GB, Trevisi L, Patrignani P, Belton O.

Prostaglandins Other Lipid Mediat. 2015 Jul;120:103-14. doi: 10.1016/j.prostaglandins.2015.03.004. Epub 2015 Mar 26.


Inhibition of lipopolysaccharide-induced gene expression by liver X receptor ligands in macrophages involves interference with early growth response factor 1.

Guillem-Llobat P, Íñiguez MA.

Prostaglandins Leukot Essent Fatty Acids. 2015 May;96:37-49. doi: 10.1016/j.plefa.2015.02.002. Epub 2015 Feb 19.


Platelets, cyclooxygenases, and colon cancer.

Guillem-Llobat P, Dovizio M, Alberti S, Bruno A, Patrignani P.

Semin Oncol. 2014 Jun;41(3):385-96. doi: 10.1053/j.seminoncol.2014.04.008. Epub 2014 Apr 24. Review.


Reappraisal of the clinical pharmacology of low-dose aspirin by comparing novel direct and traditional indirect biomarkers of drug action.

Patrignani P, Tacconelli S, Piazuelo E, Di Francesco L, Dovizio M, Sostres C, Marcantoni E, Guillem-Llobat P, Del Boccio P, Zucchelli M, Patrono C, Lanas A.

J Thromb Haemost. 2014 Aug;12(8):1320-30. doi: 10.1111/jth.12637. Epub 2014 Jul 18.


Role of platelets in inflammation and cancer: novel therapeutic strategies.

Dovizio M, Alberti S, Guillem-Llobat P, Patrignani P.

Basic Clin Pharmacol Toxicol. 2014 Jan;114(1):118-27. doi: 10.1111/bcpt.12156. Epub 2013 Nov 8. Review.

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