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Dynamic Performance of an Oil Starved Squeeze Film Damper Combined With a Cylindrical Roller Bearing.

Meeus H, Fiszer J, Van De Velde G, Verrelst B, Lefeber D, Guillaume P, Desmet W.

J Eng Gas Turbine Power. 2019 Jul;141(7):0710091-7100912. doi: 10.1115/1.4042418. Epub 2019 Feb 6.


The Length Distribution and Multiple Specificity of Naturally Presented HLA-I Ligands.

Gfeller D, Guillaume P, Michaux J, Pak HS, Daniel RT, Racle J, Coukos G, Bassani-Sternberg M.

J Immunol. 2018 Dec 15;201(12):3705-3716. doi: 10.4049/jimmunol.1800914. Epub 2018 Nov 14.


OBE022, an Oral and Selective Prostaglandin F2α Receptor Antagonist as an Effective and Safe Modality for the Treatment of Preterm Labor.

Pohl O, Chollet A, Kim SH, Riaposova L, Spézia F, Gervais F, Guillaume P, Lluel P, Méen M, Lemaux F, Terzidou V, Bennett PR, Gotteland JP.

J Pharmacol Exp Ther. 2018 Aug;366(2):349-364. doi: 10.1124/jpet.118.247668. Epub 2018 May 18.


The C-terminal extension landscape of naturally presented HLA-I ligands.

Guillaume P, Picaud S, Baumgaertner P, Montandon N, Schmidt J, Speiser DE, Coukos G, Bassani-Sternberg M, Filippakopoulos P, Gfeller D.

Proc Natl Acad Sci U S A. 2018 May 15;115(20):5083-5088. doi: 10.1073/pnas.1717277115. Epub 2018 Apr 30.


Sensitive and frequent identification of high avidity neo-epitope specific CD8 + T cells in immunotherapy-naive ovarian cancer.

Bobisse S, Genolet R, Roberti A, Tanyi JL, Racle J, Stevenson BJ, Iseli C, Michel A, Le Bitoux MA, Guillaume P, Schmidt J, Bianchi V, Dangaj D, Fenwick C, Derré L, Xenarios I, Michielin O, Romero P, Monos DS, Zoete V, Gfeller D, Kandalaft LE, Coukos G, Harari A.

Nat Commun. 2018 Mar 15;9(1):1092. doi: 10.1038/s41467-018-03301-0.


Fatigue Performance of Ti-6Al-4V Additively Manufactured Specimens with Integrated Capillaries of an Embedded Structural Health Monitoring System.

Hinderdael M, Strantza M, De Baere D, Devesse W, De Graeve I, Terryn H, Guillaume P.

Materials (Basel). 2017 Aug 25;10(9). pii: E993. doi: 10.3390/ma10090993.


Deciphering HLA-I motifs across HLA peptidomes improves neo-antigen predictions and identifies allostery regulating HLA specificity.

Bassani-Sternberg M, Chong C, Guillaume P, Solleder M, Pak H, Gannon PO, Kandalaft LE, Coukos G, Gfeller D.

PLoS Comput Biol. 2017 Aug 23;13(8):e1005725. doi: 10.1371/journal.pcbi.1005725. eCollection 2017 Aug.


In silico and cell-based analyses reveal strong divergence between prediction and observation of T-cell-recognized tumor antigen T-cell epitopes.

Schmidt J, Guillaume P, Dojcinovic D, Karbach J, Coukos G, Luescher I.

J Biol Chem. 2017 Jul 14;292(28):11840-11849. doi: 10.1074/jbc.M117.789511. Epub 2017 May 23.


Dose to organ at risk and dose prescription in liver SBRT.

Michel R, Françoise I, Laure P, Anouchka M, Guillaume P, Sylvain K.

Rep Pract Oncol Radiother. 2017 Mar-Apr;22(2):96-102. doi: 10.1016/j.rpor.2017.03.001. Epub 2017 Apr 17. Review.


The logic of transcriptional regulator recruitment architecture at cis-regulatory modules controlling liver functions.

Dubois-Chevalier J, Dubois V, Dehondt H, Mazrooei P, Mazuy C, Sérandour AA, Gheeraert C, Guillaume P, Baugé E, Derudas B, Hennuyer N, Paumelle R, Marot G, Carroll JS, Lupien M, Staels B, Lefebvre P, Eeckhoute J.

Genome Res. 2017 Jun;27(6):985-996. doi: 10.1101/gr.217075.116. Epub 2017 Apr 11.


Proof of Concept of Integrated Load Measurement in 3D Printed Structures.

Hinderdael M, Jardon Z, Lison M, De Baere D, Devesse W, Strantza M, Guillaume P.

Sensors (Basel). 2017 Feb 9;17(2). pii: E328. doi: 10.3390/s17020328.


High Resolution Temperature Measurement of Liquid Stainless Steel Using Hyperspectral Imaging.

Devesse W, De Baere D, Guillaume P.

Sensors (Basel). 2017 Jan 5;17(1). pii: E91. doi: 10.3390/s17010091.


An optimized single chain TCR scaffold relying on the assembly with the native CD3-complex prevents residual mispairing with endogenous TCRs in human T-cells.

Knies D, Klobuch S, Xue SA, Birtel M, Echchannaoui H, Yildiz O, Omokoko T, Guillaume P, Romero P, Stauss H, Sahin U, Herr W, Theobald M, Thomas S, Voss RH.

Oncotarget. 2016 Apr 19;7(16):21199-221. doi: 10.18632/oncotarget.8385.


Fatigue of Ti6Al4V Structural Health Monitoring Systems Produced by Selective Laser Melting.

Strantza M, Vafadari R, de Baere D, Vrancken B, van Paepegem W, Vandendael I, Terryn H, Guillaume P, van Hemelrijck D.

Materials (Basel). 2016 Feb 11;9(2). pii: E106. doi: 10.3390/ma9020106.


Evaluation of SHM system produced by additive manufacturing via acoustic emission and other NDT methods.

Strantza M, Aggelis DG, de Baere D, Guillaume P, van Hemelrijck D.

Sensors (Basel). 2015 Oct 21;15(10):26709-25. doi: 10.3390/s151026709.


Vaccination with LAG-3Ig (IMP321) and Peptides Induces Specific CD4 and CD8 T-Cell Responses in Metastatic Melanoma Patients--Report of a Phase I/IIa Clinical Trial.

Legat A, Maby-El Hajjami H, Baumgaertner P, Cagnon L, Abed Maillard S, Geldhof C, Iancu EM, Lebon L, Guillaume P, Dojcinovic D, Michielin O, Romano E, Berthod G, Rimoldi D, Triebel F, Luescher I, Rufer N, Speiser DE.

Clin Cancer Res. 2016 Mar 15;22(6):1330-40. doi: 10.1158/1078-0432.CCR-15-1212. Epub 2015 Oct 23.


Underwater Acoustic Wavefront Visualization by Scanning Laser Doppler Vibrometer for the Characterization of Focused Ultrasonic Transducers.

Longo R, Vanlanduit S, Arroud G, Guillaume P.

Sensors (Basel). 2015 Aug 13;15(8):19925-36. doi: 10.3390/s150819925.


Identification of Rare High-Avidity, Tumor-Reactive CD8+ T Cells by Monomeric TCR-Ligand Off-Rates Measurements on Living Cells.

Hebeisen M, Schmidt J, Guillaume P, Baumgaertner P, Speiser DE, Luescher I, Rufer N.

Cancer Res. 2015 May 15;75(10):1983-91. doi: 10.1158/0008-5472.CAN-14-3516. Epub 2015 Mar 25.


Corrigendum: the antimicrobial peptide LL37 is a T-cell autoantigen in psoriasis.

Lande R, Botti E, Jandus C, Dojcinovic D, Fanelli G, Conrad C, Chamilos G, Feldmeyer L, Marinari B, Chon S, Vence L, Riccieri V, Guillaume P, Navarini AA, Romero P, Costanzo A, Piccolella E, Gilliet M, Frasca L.

Nat Commun. 2015 Mar 11;6:6595. doi: 10.1038/ncomms7595. No abstract available.


The antimicrobial peptide LL37 is a T-cell autoantigen in psoriasis.

Lande R, Botti E, Jandus C, Dojcinovic D, Fanelli G, Conrad C, Chamilos G, Feldmeyer L, Marinari B, Chon S, Vence L, Riccieri V, Guillaume P, Navarini AA, Romero P, Costanzo A, Piccolella E, Gilliet M, Frasca L.

Nat Commun. 2014 Dec 3;5:5621. doi: 10.1038/ncomms6621. Erratum in: Nat Commun. 2015;6:6595.


Comparison of the effects of clonidine, loperamide and metoclopramide in two models of gastric emptying in the rat.

Goineau S, Guillaume P, Castagné V.

Fundam Clin Pharmacol. 2015 Feb;29(1):86-94. doi: 10.1111/fcp.12086. Epub 2014 Oct 2.


Automated analysis of delayed emesis in the telemetered ferret: detection of synergistic effects of aprepitant and ondansetron.

Goineau S, Guillaume P, Barrais L, Castagné V.

Fundam Clin Pharmacol. 2014 Dec;28(6):643-51. doi: 10.1111/fcp.12082. Epub 2014 May 19.


PD-1 and Tim-3 regulate the expansion of tumor antigen-specific CD8⁺ T cells induced by melanoma vaccines.

Fourcade J, Sun Z, Pagliano O, Chauvin JM, Sander C, Janjic B, Tarhini AA, Tawbi HA, Kirkwood JM, Moschos S, Wang H, Guillaume P, Luescher IF, Krieg A, Anderson AC, Kuchroo VK, Zarour HM.

Cancer Res. 2014 Feb 15;74(4):1045-55. doi: 10.1158/0008-5472.CAN-13-2908. Epub 2013 Dec 16.


Tris-ACE-α-cyclodextrin tripods: chemistry and metal coordination behaviour.

Guillaume P, Florence DC, Alain M.

Dalton Trans. 2013 Dec 28;42(48):16806-17. doi: 10.1039/c3dt51811f. Epub 2013 Oct 1.


Hydroxypropyl-β-cyclodextrin impacts renal and systemic hemodynamics in the anesthetized dog.

Rosseels ML, Delaunois AG, Hanon E, Guillaume PJ, Martin FD, van den Dobbelsteen DJ.

Regul Toxicol Pharmacol. 2013 Dec;67(3):351-9. doi: 10.1016/j.yrtph.2013.08.013. Epub 2013 Aug 23.


Analysis, Isolation, and Activation of Antigen-Specific CD4(+) and CD8(+) T Cells by Soluble MHC-Peptide Complexes.

Schmidt J, Dojcinovic D, Guillaume P, Luescher I.

Front Immunol. 2013 Jul 30;4:218. doi: 10.3389/fimmu.2013.00218. eCollection 2013.


An overview of QT interval assessment in safety pharmacology.

Guillaume P, Goineau S, Froget G.

Curr Protoc Pharmacol. 2013 Jun;Chapter 10:Unit 10.7. doi: 10.1002/0471141755.ph1007s61. Review.


Using telemetry to automate the detection of emesis in the ferret: new vistas for delayed emesis assessment.

Goineau S, Rompion S, Guillaume P, Barrais L, Castagné V.

J Pharmacol Toxicol Methods. 2013 Jul-Aug;68(1):160-5. doi: 10.1016/j.vascn.2013.03.010. Epub 2013 Apr 9.


CSP--a model for in vivo presentation of Plasmodium berghei sporozoite antigens by hepatocytes.

Balam S, Romero JF, Bongfen SE, Guillaume P, Corradin G.

PLoS One. 2012;7(12):e51875. doi: 10.1371/journal.pone.0051875. Epub 2012 Dec 18.


Donor lymphocyte infusion induces polyspecific CD8(+) T-cell responses with concurrent molecular remission in acute myeloid leukemia with NPM1 mutation.

Hofmann S, Götz M, Schneider V, Guillaume P, Bunjes D, Döhner H, Wiesneth M, Greiner J.

J Clin Oncol. 2013 Jan 20;31(3):e44-7. doi: 10.1200/JCO.2011.41.1116. Epub 2012 Dec 17. No abstract available.


An optimized method for establishing high purity murine CD8+ T cell cultures.

Zanker D, Xiao K, Oveissi S, Guillaume P, Luescher IF, Chen W.

J Immunol Methods. 2013 Jan 31;387(1-2):173-80. doi: 10.1016/j.jim.2012.10.012. Epub 2012 Oct 22.


A novel HLA-B18 restricted CD8+ T cell epitope is efficiently cross-presented by dendritic cells from soluble tumor antigen.

Zhao RY, Mifsud NA, Xiao K, Chan KF, Oveissi S, Jackson HM, Dimopoulos N, Guillaume P, Knights AJ, Lowen T, Robson NC, Russell SE, Scotet E, Davis ID, Maraskovsky E, Cebon J, Luescher IF, Chen W.

PLoS One. 2012;7(9):e44707. doi: 10.1371/journal.pone.0044707. Epub 2012 Sep 6.


The comparative sensitivity of three in vitro safety pharmacology models for the detection of lidocaine-induced cardiac effects.

Goineau S, Castagné V, Guillaume P, Froget G.

J Pharmacol Toxicol Methods. 2012 Jul;66(1):52-8. doi: 10.1016/j.vascn.2012.06.001. Epub 2012 Jun 9.


Mutated regions of nucleophosmin 1 elicit both CD4(+) and CD8(+) T-cell responses in patients with acute myeloid leukemia.

Greiner J, Ono Y, Hofmann S, Schmitt A, Mehring E, Götz M, Guillaume P, Döhner K, Mytilineos J, Döhner H, Schmitt M.

Blood. 2012 Aug 9;120(6):1282-9. doi: 10.1182/blood-2011-11-394395. Epub 2012 May 16.


Interplay between T cell receptor binding kinetics and the level of cognate peptide presented by major histocompatibility complexes governs CD8+ T cell responsiveness.

Irving M, Zoete V, Hebeisen M, Schmid D, Baumgartner P, Guillaume P, Romero P, Speiser D, Luescher I, Rufer N, Michielin O.

J Biol Chem. 2012 Jun 29;287(27):23068-78. doi: 10.1074/jbc.M112.357673. Epub 2012 May 1.


CD8(+) T cells specific for tumor antigens can be rendered dysfunctional by the tumor microenvironment through upregulation of the inhibitory receptors BTLA and PD-1.

Fourcade J, Sun Z, Pagliano O, Guillaume P, Luescher IF, Sander C, Kirkwood JM, Olive D, Kuchroo V, Zarour HM.

Cancer Res. 2012 Feb 15;72(4):887-96. doi: 10.1158/0008-5472.CAN-11-2637. Epub 2011 Dec 28.


Enhanced cytotoxicity and decreased CD8 dependence of human cancer-specific cytotoxic T lymphocytes after vaccination with low peptide dose.

Lövgren T, Baumgaertner P, Wieckowski S, Devêvre E, Guillaume P, Luescher I, Rufer N, Speiser DE.

Cancer Immunol Immunother. 2012 Jun;61(6):817-26. doi: 10.1007/s00262-011-1140-1. Epub 2011 Nov 12.


Reversible major histocompatibility complex I-peptide multimers containing Ni(2+)-nitrilotriacetic acid peptides and histidine tags improve analysis and sorting of CD8(+) T cells.

Schmidt J, Guillaume P, Irving M, Baumgaertner P, Speiser D, Luescher IF.

J Biol Chem. 2011 Dec 2;286(48):41723-35. doi: 10.1074/jbc.M111.283127. Epub 2011 Oct 11.


Supplemental studies for cardiovascular risk assessment in safety pharmacology: a critical overview.

Picard S, Goineau S, Guillaume P, Henry J, Hanouz JL, Rouet R.

Cardiovasc Toxicol. 2011 Dec;11(4):285-307. doi: 10.1007/s12012-011-9133-z. Review.


Vaccination-induced functional competence of circulating human tumor-specific CD8 T-cells.

Baumgaertner P, Jandus C, Rivals JP, Derré L, Lövgren T, Baitsch L, Guillaume P, Luescher IF, Berthod G, Matter M, Rufer N, Michielin O, Speiser DE.

Int J Cancer. 2012 Jun 1;130(11):2607-17. doi: 10.1002/ijc.26297. Epub 2011 Aug 24.


Combination of lentivector immunization and low-dose chemotherapy or PD-1/PD-L1 blocking primes self-reactive T cells and induces anti-tumor immunity.

Sierro SR, Donda A, Perret R, Guillaume P, Yagita H, Levy F, Romero P.

Eur J Immunol. 2011 Aug;41(8):2217-28. doi: 10.1002/eji.201041235. Epub 2011 May 27.


Continuous evaluation of drug withdrawal in the rat using telemetry: effects of morphine and chlordiazepoxide.

Froger-Colléaux C, Rompion S, Guillaume P, Porsolt RD, Castagné V, Moser P.

J Pharmacol Toxicol Methods. 2011 Jul-Aug;64(1):81-8. doi: 10.1016/j.vascn.2011.03.001. Epub 2011 Mar 23.


Endothelin-converting enzyme/neutral endopeptidase inhibitor SLV338 prevents hypertensive cardiac remodeling in a blood pressure-independent manner.

Kalk P, Sharkovska Y, Kashina E, von Websky K, Relle K, Pfab T, Alter M, Guillaume P, Provost D, Hoffmann K, Fischer Y, Hocher B.

Hypertension. 2011 Apr;57(4):755-63. doi: 10.1161/HYPERTENSIONAHA.110.163972. Epub 2011 Feb 21.


Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen-specific CD8+ T cell dysfunction in melanoma patients.

Fourcade J, Sun Z, Benallaoua M, Guillaume P, Luescher IF, Sander C, Kirkwood JM, Kuchroo V, Zarour HM.

J Exp Med. 2010 Sep 27;207(10):2175-86. doi: 10.1084/jem.20100637. Epub 2010 Sep 6.


Peptide vaccine induces enhanced tumor growth associated with apoptosis induction in CD8+ T cells.

Muraoka D, Kato T, Wang L, Maeda Y, Noguchi T, Harada N, Takeda K, Yagita H, Guillaume P, Luescher I, Old LJ, Shiku H, Nishikawa H.

J Immunol. 2010 Sep 15;185(6):3768-76. doi: 10.4049/jimmunol.0903649. Epub 2010 Aug 23.


Ventilatory function assessment in safety pharmacology: optimization of rodent studies using normocapnic or hypercapnic conditions.

Goineau S, Rompion S, Guillaume P, Picard S.

Toxicol Appl Pharmacol. 2010 Sep 15;247(3):191-7. doi: 10.1016/j.taap.2010.06.012. Epub 2010 Jun 20.


Coexpression of the T-cell receptor constant alpha domain triggers tumor reactivity of single-chain TCR-transduced human T cells.

Voss RH, Thomas S, Pfirschke C, Hauptrock B, Klobuch S, Kuball J, Grabowski M, Engel R, Guillaume P, Romero P, Huber C, Beckhove P, Theobald M.

Blood. 2010 Jun 24;115(25):5154-63. doi: 10.1182/blood-2009-11-254078. Epub 2010 Apr 8.


Simultaneous determination of acoustic velocity and density of a cortical bone slab: ultrasonic model-based approach.

Longo R, Grimal Q, Laugier P, Vanlanduit S, Guillaume P.

IEEE Trans Ultrason Ferroelectr Freq Control. 2010;57(2):496-500. doi: 10.1109/TUFFC.2010.1430.


Novel soluble HLA-A2/MELAN-A complexes selectively stain a differentiation defective subpopulation of CD8+ T cells in patients with melanoma.

Guillaume P, Baumgaertner P, Neff L, Rufer N, Wettstein P, Speiser DE, Luescher IF.

Int J Cancer. 2010 Aug 15;127(4):910-23. doi: 10.1002/ijc.25099.


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