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Items: 6

1.

p27 allosterically activates cyclin-dependent kinase 4 and antagonizes palbociclib inhibition.

Guiley KZ, Stevenson JW, Lou K, Barkovich KJ, Kumarasamy V, Wijeratne TU, Bunch KL, Tripathi S, Knudsen ES, Witkiewicz AK, Shokat KM, Rubin SM.

Science. 2019 Dec 13;366(6471). pii: eaaw2106. doi: 10.1126/science.aaw2106.

PMID:
31831640
2.

Structural mechanism of Myb-MuvB assembly.

Guiley KZ, Iness AN, Saini S, Tripathi S, Lipsick JS, Litovchick L, Rubin SM.

Proc Natl Acad Sci U S A. 2018 Oct 2;115(40):10016-10021. doi: 10.1073/pnas.1808136115. Epub 2018 Sep 17.

3.

The cell cycle regulatory DREAM complex is disrupted by high expression of oncogenic B-Myb.

Iness AN, Felthousen J, Ananthapadmanabhan V, Sesay F, Saini S, Guiley KZ, Rubin SM, Dozmorov M, Litovchick L.

Oncogene. 2019 Feb;38(7):1080-1092. doi: 10.1038/s41388-018-0490-y. Epub 2018 Sep 11.

4.

Structural mechanisms of DREAM complex assembly and regulation.

Guiley KZ, Liban TJ, Felthousen JG, Ramanan P, Litovchick L, Rubin SM.

Genes Dev. 2015 May 1;29(9):961-74. doi: 10.1101/gad.257568.114. Epub 2015 Apr 27.

5.

The molecular architecture of human Dicer.

Lau PW, Guiley KZ, De N, Potter CS, Carragher B, MacRae IJ.

Nat Struct Mol Biol. 2012 Mar 18;19(4):436-40. doi: 10.1038/nsmb.2268.

6.

Single-pot enzymatic synthesis of Dicer-substrate siRNAs.

Guiley KZ, Pratt AJ, MacRae IJ.

Nucleic Acids Res. 2012 Mar;40(5):e40. doi: 10.1093/nar/gkr1174. Epub 2011 Dec 20.

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