Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 334


Step-Wise Chondrogenesis of Human Induced Pluripotent Stem Cells and Purification Via a Reporter Allele Generated by CRISPR-Cas9 Genome Editing.

Adkar SS, Wu CL, Willard VP, Dicks A, Ettyreddy A, Steward N, Bhutani N, Gersbach CA, Guilak F.

Stem Cells. 2018 Oct 31. doi: 10.1002/stem.2931. [Epub ahead of print]


Obesity alters the in vivo mechanical response and biochemical properties of cartilage as measured by MRI.

Collins AT, Kulvaranon ML, Cutcliffe HC, Utturkar GM, Smith WAR, Spritzer CE, Guilak F, DeFrate LE.

Arthritis Res Ther. 2018 Oct 17;20(1):232. doi: 10.1186/s13075-018-1727-4.


Selective Enzymatic Digestion of Proteoglycans and Collagens Alters Cartilage T1rho and T2 Relaxation Times.

Collins AT, Hatcher CC, Kim SY, Ziemian SN, Spritzer CE, Guilak F, DeFrate LE, McNulty AL.

Ann Biomed Eng. 2018 Oct 4. doi: 10.1007/s10439-018-02143-7. [Epub ahead of print]


Composite Cellularized Structures Created from an Interpenetrating Polymer Network Hydrogel Reinforced by a 3D Woven Scaffold.

Moffat KL, Goon K, Moutos FT, Estes BT, Oswald SJ, Zhao X, Guilak F.

Macromol Biosci. 2018 Oct;18(10):e1800140. doi: 10.1002/mabi.201800140. Epub 2018 Jul 24.


High-depth transcriptomic profiling reveals the temporal gene signature of human mesenchymal stem cells during chondrogenesis.

Huynh NPT, Zhang B, Guilak F.

FASEB J. 2018 Jul 9:fj201800534R. doi: 10.1096/fj.201800534R. [Epub ahead of print]


Regulation of decellularized tissue remodeling via scaffold-mediated lentiviral delivery in anatomically-shaped osteochondral constructs.

Rowland CR, Glass KA, Ettyreddy AR, Gloss CC, Matthews JRL, Huynh NPT, Guilak F.

Biomaterials. 2018 Sep;177:161-175. doi: 10.1016/j.biomaterials.2018.04.049. Epub 2018 May 30.


Osteoarthritis as a disease of the cartilage pericellular matrix.

Guilak F, Nims RJ, Dicks A, Wu CL, Meulenbelt I.

Matrix Biol. 2018 Oct;71-72:40-50. doi: 10.1016/j.matbio.2018.05.008. Epub 2018 May 22. Review.


Publication trends in spine research from 2007 to 2016: Comparison of the Orthopaedic Research Society Spine Section and the International Society for the Study of the Lumbar Spine.

Martin JT, Gullbrand SE, Fields AJ, Purmessur D, Diwan AD, Oxland TR, Chiba K, Guilak F, Hoyland JA, Iatridis JC.

JOR Spine. 2018 Mar;1(1):e1006. doi: 10.1002/jsp2.1006. Epub 2018 Mar 23.


Genetic Engineering of Mesenchymal Stem Cells for Differential Matrix Deposition on 3D Woven Scaffolds.

Huynh NPT, Brunger JM, Gloss CC, Moutos FT, Gersbach CA, Guilak F.

Tissue Eng Part A. 2018 Oct;24(19-20):1531-1544. doi: 10.1089/ten.TEA.2017.0510. Epub 2018 Jul 13.


Chondrogenic Differentiation Processes in Human Bone-Marrow Aspirates Seeded in Three-Dimensional-Woven Poly(ɛ-Caprolactone) Scaffolds Enhanced by Recombinant Adeno-Associated Virus-Mediated SOX9 Gene Transfer.

Venkatesan JK, Moutos FT, Rey-Rico A, Estes BT, Frisch J, Schmitt G, Madry H, Guilak F, Cucchiarini M.

Hum Gene Ther. 2018 Nov;29(11):1277-1286. doi: 10.1089/hum.2017.165. Epub 2018 Jun 11.


Differentiation of human induced pluripotent stem cells into nucleus pulposus-like cells.

Tang R, Jing L, Willard VP, Wu CL, Guilak F, Chen J, Setton LA.

Stem Cell Res Ther. 2018 Mar 9;9(1):61. doi: 10.1186/s13287-018-0797-1.


Dynamics and mechanisms of intracellular calcium waves elicited by tandem bubble-induced jetting flow.

Li F, Yang C, Yuan F, Liao D, Li T, Guilak F, Zhong P.

Proc Natl Acad Sci U S A. 2018 Jan 16;115(3):E353-E362. doi: 10.1073/pnas.1713905115. Epub 2017 Dec 27.


Perspectives on Sharing Models and Related Resources in Computational Biomechanics Research.

Erdemir A, Hunter PJ, Holzapfel GA, Loew LM, Middleton J, Jacobs CR, Nithiarasu P, Löhner R, Wei G, Winkelstein BA, Barocas VH, Guilak F, Ku JP, Hicks JL, Delp SL, Sacks M, Weiss JA, Ateshian GA, Maas SA, McCulloch AD, Peng GCY.

J Biomech Eng. 2018 Feb 1;140(2). doi: 10.1115/1.4038768.


Canine hip dysplasia: A natural animal model for human developmental dysplasia of the hip.

Pascual-Garrido C, Guilak F, Rai MF, Harris MD, Lopez MJ, Todhunter RJ, Clohisy JC.

J Orthop Res. 2018 Jul;36(7):1807-1817. doi: 10.1002/jor.23828. Epub 2018 Feb 27.


Increased Ca2+ signaling through CaV1.2 promotes bone formation and prevents estrogen deficiency-induced bone loss.

Cao C, Ren Y, Barnett AS, Mirando AJ, Rouse D, Mun SH, Park-Min KH, McNulty AL, Guilak F, Karner CM, Hilton MJ, Pitt GS.

JCI Insight. 2017 Nov 16;2(22). pii: 95512. doi: 10.1172/jci.insight.95512. [Epub ahead of print]


CXCL10 is upregulated in synovium and cartilage following articular fracture.

Furman BD, Kent CL, Huebner JL, Kraus VB, McNulty AL, Guilak F, Olson SA.

J Orthop Res. 2018 Apr;36(4):1220-1227. doi: 10.1002/jor.23735. Epub 2017 Nov 20.


Genome Engineering for Personalized Arthritis Therapeutics.

Adkar SS, Brunger JM, Willard VP, Wu CL, Gersbach CA, Guilak F.

Trends Mol Med. 2017 Oct;23(10):917-931. doi: 10.1016/j.molmed.2017.08.002. Epub 2017 Sep 5. Review.


Role of Piezo Channels in Joint Health and Injury.

Lee W, Guilak F, Liedtke W.

Curr Top Membr. 2017;79:263-273. doi: 10.1016/bs.ctm.2016.10.003. Epub 2017 Jan 11. Review.


Conditional Macrophage Depletion Increases Inflammation and Does Not Inhibit the Development of Osteoarthritis in Obese Macrophage Fas-Induced Apoptosis-Transgenic Mice.

Wu CL, McNeill J, Goon K, Little D, Kimmerling K, Huebner J, Kraus V, Guilak F.

Arthritis Rheumatol. 2017 Sep;69(9):1772-1783. doi: 10.1002/art.40161. Epub 2017 Aug 8.


Genome Engineering of Stem Cells for Autonomously Regulated, Closed-Loop Delivery of Biologic Drugs.

Brunger JM, Zutshi A, Willard VP, Gersbach CA, Guilak F.

Stem Cell Reports. 2017 May 9;8(5):1202-1213. doi: 10.1016/j.stemcr.2017.03.022. Epub 2017 Apr 27.


Regulation of human nucleus pulposus cells by peptide-coupled substrates.

Bridgen DT, Fearing BV, Jing L, Sanchez-Adams J, Cohan MC, Guilak F, Chen J, Setton LA.

Acta Biomater. 2017 Jun;55:100-108. doi: 10.1016/j.actbio.2017.04.019. Epub 2017 Apr 20.


Comparison of Fixation Techniques of 3D-Woven Poly(ϵ-Caprolactone) Scaffolds for Cartilage Repair in a Weightbearing Porcine Large Animal Model.

Friedman JM, Sennett ML, Bonadio MB, Orji KO, Neuwirth AL, Keah N, Carey JL, Moutos FT, Estes BT, Guilak F, Madry H, Mauck RL, Dodge GR.

Cartilage. 2018 Oct;9(4):428-437. doi: 10.1177/1947603517700953. Epub 2017 Apr 11.


Serum and synovial fluid lipidomic profiles predict obesity-associated osteoarthritis, synovitis, and wound repair.

Wu CL, Kimmerling KA, Little D, Guilak F.

Sci Rep. 2017 Mar 20;7:44315. doi: 10.1038/srep44315.


Mechanical Signals as Regulators of Cartilage Degeneration and Regeneration.

Rai MF, Stoddart MJ, Guilak F.

J Am Acad Orthop Surg. 2017 Apr;25(4):e87-e89. doi: 10.5435/JAAOS-D-16-00938. No abstract available.


New tools for Content Innovation and data sharing: Enhancing reproducibility and rigor in biomechanics research.

Guilak F.

J Biomech. 2017 Mar 21;54:1-3. doi: 10.1016/j.jbiomech.2017.01.044. Epub 2017 Feb 10.


Relationship between T1rho magnetic resonance imaging, synovial fluid biomarkers, and the biochemical and biomechanical properties of cartilage.

Hatcher CC, Collins AT, Kim SY, Michel LC, Mostertz WC 3rd, Ziemian SN, Spritzer CE, Guilak F, DeFrate LE, McNulty AL.

J Biomech. 2017 Apr 11;55:18-26. doi: 10.1016/j.jbiomech.2017.02.001. Epub 2017 Feb 6.


* CRISPR-Based Epigenome Editing of Cytokine Receptors for the Promotion of Cell Survival and Tissue Deposition in Inflammatory Environments.

Farhang N, Brunger JM, Stover JD, Thakore PI, Lawrence B, Guilak F, Gersbach CA, Setton LA, Bowles RD.

Tissue Eng Part A. 2017 Aug;23(15-16):738-749. doi: 10.1089/ten.TEA.2016.0441. Epub 2017 Feb 28.


On the Functional Role of Valve Interstitial Cell Stress Fibers: A Continuum Modeling Approach.

Sakamoto Y, Buchanan RM, Sanchez-Adams J, Guilak F, Sacks MS.

J Biomech Eng. 2017 Feb 1;139(2). doi: 10.1115/1.4035557. Review.


Matrix metalloproteinase activity and prostaglandin E2 are elevated in the synovial fluid of meniscus tear patients.

Liu B, Goode AP, Carter TE, Utturkar GM, Huebner JL, Taylor DC, Moorman CT 3rd, Garrett WE, Kraus VB, Guilak F, DeFrate LE, McNulty AL.

Connect Tissue Res. 2017 May - Jul;58(3-4):305-316. doi: 10.1080/03008207.2016.1256391. Epub 2016 Nov 4.


CRISPR/Cas9 Editing of Murine Induced Pluripotent Stem Cells for Engineering Inflammation-Resistant Tissues.

Brunger JM, Zutshi A, Willard VP, Gersbach CA, Guilak F.

Arthritis Rheumatol. 2017 May;69(5):1111-1121. doi: 10.1002/art.39982. Epub 2017 Mar 31.


Loss of stiffness in collagen-rich uterine fibroids after digestion with purified collagenase Clostridium histolyticum.

Jayes FL, Liu B, Moutos FT, Kuchibhatla M, Guilak F, Leppert PC.

Am J Obstet Gynecol. 2016 Nov;215(5):596.e1-596.e8. doi: 10.1016/j.ajog.2016.05.006. Epub 2016 May 10.


Functional outcome measures in a surgical model of hip osteoarthritis in dogs.

Little D, Johnson S, Hash J, Olson SA, Estes BT, Moutos FT, Lascelles BD, Guilak F.

J Exp Orthop. 2016 Dec;3(1):17. doi: 10.1186/s40634-016-0053-5. Epub 2016 Aug 15.


Anatomically shaped tissue-engineered cartilage with tunable and inducible anticytokine delivery for biological joint resurfacing.

Moutos FT, Glass KA, Compton SA, Ross AK, Gersbach CA, Guilak F, Estes BT.

Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):E4513-22. doi: 10.1073/pnas.1601639113. Epub 2016 Jul 18.


Cartilage-Specific Knockout of the Mechanosensory Ion Channel TRPV4 Decreases Age-Related Osteoarthritis.

O'Conor CJ, Ramalingam S, Zelenski NA, Benefield HC, Rigo I, Little D, Wu CL, Chen D, Liedtke W, McNulty AL, Guilak F.

Sci Rep. 2016 Jul 8;6:29053. doi: 10.1038/srep29053.


Dedifferentiated Human Articular Chondrocytes Redifferentiate to a Cartilage-Like Tissue Phenotype in a Poly(ε-Caprolactone)/Self-Assembling Peptide Composite Scaffold.

Recha-Sancho L, Moutos FT, Abellà J, Guilak F, Semino CE.

Materials (Basel). 2016 Jun 17;9(6). pii: E472. doi: 10.3390/ma9060472.


N-cadherin is Key to Expression of the Nucleus Pulposus Cell Phenotype under Selective Substrate Culture Conditions.

Hwang PY, Jing L, Chen J, Lim FL, Tang R, Choi H, Cheung KM, Risbud MV, Gersbach CA, Guilak F, Leung VY, Setton LA.

Sci Rep. 2016 Jun 13;6:28038. doi: 10.1038/srep28038.


Emerging roles for long noncoding RNAs in skeletal biology and disease.

Huynh NP, Anderson BA, Guilak F, McAlinden A.

Connect Tissue Res. 2017 Jan;58(1):116-141. doi: 10.1080/03008207.2016.1194406. Epub 2016 Jun 2. Review.


Small molecule dual-inhibitors of TRPV4 and TRPA1 for attenuation of inflammation and pain.

Kanju P, Chen Y, Lee W, Yeo M, Lee SH, Romac J, Shahid R, Fan P, Gooden DM, Simon SA, Spasojevic I, Mook RA, Liddle RA, Guilak F, Liedtke WB.

Sci Rep. 2016 Jun 1;6:26894. doi: 10.1038/srep26894.


Exploratory secondary analyses of a cognitive-behavioral intervention for knee osteoarthritis demonstrate reduction in biomarkers of adipocyte inflammation.

Huebner JL, Landerman LR, Somers TJ, Keefe FJ, Guilak F, Blumenthal JA, Caldwell DS, Kraus VB.

Osteoarthritis Cartilage. 2016 Sep;24(9):1528-34. doi: 10.1016/j.joca.2016.04.002. Epub 2016 Apr 16.


Advances in combining gene therapy with cell and tissue engineering-based approaches to enhance healing of the meniscus.

Cucchiarini M, McNulty AL, Mauck RL, Setton LA, Guilak F, Madry H.

Osteoarthritis Cartilage. 2016 Aug;24(8):1330-9. doi: 10.1016/j.joca.2016.03.018. Epub 2016 Apr 5. Review.


Fabrication of anatomically-shaped cartilage constructs using decellularized cartilage-derived matrix scaffolds.

Rowland CR, Colucci LA, Guilak F.

Biomaterials. 2016 Jun;91:57-72. doi: 10.1016/j.biomaterials.2016.03.012. Epub 2016 Mar 9.


Universally Conserved Relationships between Nuclear Shape and Cytoplasmic Mechanical Properties in Human Stem Cells.

Lozoya OA, Gilchrist CL, Guilak F.

Sci Rep. 2016 Mar 15;6:23047. doi: 10.1038/srep23047.


Reply to "Does progranulin account for the opposite effects of etanercept and infliximab/adalimumab in osteoarthritis?" by Wei et al.

Olson SA, Furman BD, Kraus VB, Huebner JL, Guilak F.

J Orthop Res. 2016 Jan;34(1):15-6. doi: 10.1002/jor.23095. Epub 2015 Dec 8. No abstract available.


3D Printing: 3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures.

Hong S, Sycks D, Chan HF, Lin S, Lopez GP, Guilak F, Leong KW, Zhao X.

Adv Mater. 2015 Jul 15;27(27):4034. doi: 10.1002/adma.201570182.


Morphogenetic Implications of Peristalsis-Driven Fluid Flow in the Embryonic Lung.

Bokka KK, Jesudason EC, Lozoya OA, Guilak F, Warburton D, Lubkin SR.

PLoS One. 2015 Jul 6;10(7):e0132015. doi: 10.1371/journal.pone.0132015. eCollection 2015.


Aligned multilayered electrospun scaffolds for rotator cuff tendon tissue engineering.

Orr SB, Chainani A, Hippensteel KJ, Kishan A, Gilchrist C, Garrigues NW, Ruch DS, Guilak F, Little D.

Acta Biomater. 2015 Sep;24:117-26. doi: 10.1016/j.actbio.2015.06.010. Epub 2015 Jun 14.


Extracellular Calcium Modulates Chondrogenic and Osteogenic Differentiation of Human Adipose-Derived Stem Cells: A Novel Approach for Osteochondral Tissue Engineering Using a Single Stem Cell Source.

Mellor LF, Mohiti-Asli M, Williams J, Kannan A, Dent MR, Guilak F, Loboa EG.

Tissue Eng Part A. 2015 Sep;21(17-18):2323-33. doi: 10.1089/ten.TEA.2014.0572. Epub 2015 Jul 13.


3D Printing of Highly Stretchable and Tough Hydrogels into Complex, Cellularized Structures.

Hong S, Sycks D, Chan HF, Lin S, Lopez GP, Guilak F, Leong KW, Zhao X.

Adv Mater. 2015 Jul 15;27(27):4035-40. doi: 10.1002/adma.201501099. Epub 2015 Jun 1.


Non-invasive mouse models of post-traumatic osteoarthritis.

Christiansen BA, Guilak F, Lockwood KA, Olson SA, Pitsillides AA, Sandell LJ, Silva MJ, van der Meulen MC, Haudenschild DR.

Osteoarthritis Cartilage. 2015 Oct;23(10):1627-38. doi: 10.1016/j.joca.2015.05.009. Epub 2015 May 21. Review.


Therapeutic opportunities to prevent post-traumatic arthritis: Lessons from the natural history of arthritis after articular fracture.

Olson SA, Furman BD, Kraus VB, Huebner JL, Guilak F.

J Orthop Res. 2015 Sep;33(9):1266-77. doi: 10.1002/jor.22940. Epub 2015 Jun 7.

Supplemental Content

Loading ...
Support Center