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Items: 1 to 50 of 86

1.

Platelet Acetyl-CoA Carboxylase Phosphorylation: A Risk Stratification Marker That Reveals Platelet-Lipid Interplay in Coronary Artery Disease Patients.

Kautbally S, Lepropre S, Onselaer MB, Le Rigoleur A, Ginion A, De Meester de Ravenstein C, Ambroise J, Boudjeltia KZ, Octave M, Wéra O, Hego A, Pincemail J, Cheramy-Bien JP, Huby T, Giera M, Gerber B, Pouleur AC, Guigas B, Vanoverschelde JL, Kefer J, Bertrand L, Oury C, Horman S, Beauloye C.

JACC Basic Transl Sci. 2019 Sep 11;4(5):596-610. doi: 10.1016/j.jacbts.2019.04.005. eCollection 2019 Sep.

2.

Immune Regulation of Metabolic Homeostasis by Helminths and Their Molecules.

van der Zande HJP, Zawistowska-Deniziak A, Guigas B.

Trends Parasitol. 2019 Oct;35(10):795-808. doi: 10.1016/j.pt.2019.07.014. Epub 2019 Sep 3. Review.

PMID:
31492623
3.

Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus.

Foretz M, Guigas B, Viollet B.

Nat Rev Endocrinol. 2019 Oct;15(10):569-589. doi: 10.1038/s41574-019-0242-2. Epub 2019 Aug 22. Review.

PMID:
31439934
4.

A single day of high-fat diet feeding induces lipid accumulation and insulin resistance in brown adipose tissue in mice.

Kuipers EN, Held NM, In Het Panhuis W, Modder M, Ruppert PMM, Kersten S, Kooijman S, Guigas B, Houtkooper RH, Rensen PCN, Boon MR.

Am J Physiol Endocrinol Metab. 2019 Nov 1;317(5):E820-E830. doi: 10.1152/ajpendo.00123.2019. Epub 2019 Aug 6.

PMID:
31386566
5.

A novel nutritional supplement prevents muscle loss and accelerates muscle mass recovery in caloric-restricted mice.

van den Hoek AM, Zondag GCM, Verschuren L, de Ruiter C, Attema J, de Wit EC, Schwerk AMK, Guigas B, Lek S, Rietman A, Strijker R, Kleemann R.

Metabolism. 2019 Aug;97:57-67. doi: 10.1016/j.metabol.2019.05.012. Epub 2019 May 31.

6.

Role of Mitochondria in the Mechanism(s) of Action of Metformin.

Vial G, Detaille D, Guigas B.

Front Endocrinol (Lausanne). 2019 May 7;10:294. doi: 10.3389/fendo.2019.00294. eCollection 2019. Review.

7.

AMPK-ACC signaling modulates platelet phospholipids and potentiates thrombus formation.

Lepropre S, Kautbally S, Octave M, Ginion A, Onselaer MB, Steinberg GR, Kemp BE, Hego A, Wéra O, Brouns S, Swieringa F, Giera M, Darley-Usmar VM, Ambroise J, Guigas B, Heemskerk J, Bertrand L, Oury C, Beauloye C, Horman S.

Blood. 2018 Sep 13;132(11):1180-1192. doi: 10.1182/blood-2018-02-831503. Epub 2018 Jul 17.

8.

Impact of rural-urban environment on metabolic profile and response to a 5-day high-fat diet.

Tahapary DL, de Ruiter K, Kurniawan F, Djuardi Y, Wang Y, Nurdin SME, Iskandar E, Minggu D, Yunir E, Guigas B, Supali T, Rensen PCN, Sartono E, Soewondo P, Harbuwono DS, Smit JWA, Yazdanbakhsh M.

Sci Rep. 2018 May 25;8(1):8149. doi: 10.1038/s41598-018-25092-6.

9.

Dietary yeast-derived mannan oligosaccharides have immune-modulatory properties but do not improve high fat diet-induced obesity and glucose intolerance.

Hoving LR, van der Zande HJP, Pronk A, Guigas B, Willems van Dijk K, van Harmelen V.

PLoS One. 2018 May 3;13(5):e0196165. doi: 10.1371/journal.pone.0196165. eCollection 2018.

10.

Assessing Mitochondrial Bioenergetics by Respirometry in Cells or Isolated Organelles.

Vial G, Guigas B.

Methods Mol Biol. 2018;1732:273-287. doi: 10.1007/978-1-4939-7598-3_18.

PMID:
29480482
11.

Determination of Adenine Nucleotide Concentrations in Cells and Tissues by High-Performance Liquid Chromatography.

García-Tardón N, Guigas B.

Methods Mol Biol. 2018;1732:229-237. doi: 10.1007/978-1-4939-7598-3_15.

PMID:
29480479
12.

Interleukin-33-Activated Islet-Resident Innate Lymphoid Cells Promote Insulin Secretion through Myeloid Cell Retinoic Acid Production.

Dalmas E, Lehmann FM, Dror E, Wueest S, Thienel C, Borsigova M, Stawiski M, Traunecker E, Lucchini FC, Dapito DH, Kallert SM, Guigas B, Pattou F, Kerr-Conte J, Maechler P, Girard JP, Konrad D, Wolfrum C, Böni-Schnetzler M, Finke D, Donath MY.

Immunity. 2017 Nov 21;47(5):928-942.e7. doi: 10.1016/j.immuni.2017.10.015.

13.

Chronic Intermittent Hypoxia Impairs Insulin Sensitivity but Improves Whole-Body Glucose Tolerance by Activating Skeletal Muscle AMPK.

Thomas A, Belaidi E, Moulin S, Horman S, van der Zon GC, Viollet B, Levy P, Bertrand L, Pepin JL, Godin-Ribuot D, Guigas B.

Diabetes. 2017 Dec;66(12):2942-2951. doi: 10.2337/db17-0186. Epub 2017 Sep 7.

14.

Editorial - Parasites and metabolic diseases.

Guigas B.

Parasite Immunol. 2017 May;39(5). doi: 10.1111/pim.12432. No abstract available.

15.

SpecPad: device-independent NMR data visualization and processing based on the novel DART programming language and Html5 Web technology.

Guigas B.

Magn Reson Chem. 2017 Sep;55(9):821-827. doi: 10.1002/mrc.4592. Epub 2017 Mar 23.

PMID:
28295580
16.

Lipid droplet dynamics and insulin sensitivity upon a 5-day high-fat diet in Caucasians and South Asians.

Gemmink A, Bakker LE, Guigas B, Kornips E, Schaart G, Meinders AE, Jazet IM, Hesselink MK.

Sci Rep. 2017 Feb 14;7:42393. doi: 10.1038/srep42393.

17.

Targeting AMPK: From Ancient Drugs to New Small-Molecule Activators.

Guigas B, Viollet B.

Exp Suppl. 2016;107:327-350. Review.

PMID:
27812986
18.

Environmental 24-hr Cycles Are Essential for Health.

Lucassen EA, Coomans CP, van Putten M, de Kreij SR, van Genugten JH, Sutorius RP, de Rooij KE, van der Velde M, Verhoeve SL, Smit JW, Löwik CW, Smits HH, Guigas B, Aartsma-Rus AM, Meijer JH.

Curr Biol. 2016 Jul 25;26(14):1843-53. doi: 10.1016/j.cub.2016.05.038. Epub 2016 Jul 14.

19.

Hypoxia-inducible factor prolyl hydroxylase 1 (PHD1) deficiency promotes hepatic steatosis and liver-specific insulin resistance in mice.

Thomas A, Belaidi E, Aron-Wisnewsky J, van der Zon GC, Levy P, Clement K, Pepin JL, Godin-Ribuot D, Guigas B.

Sci Rep. 2016 Apr 20;6:24618. doi: 10.1038/srep24618.

20.

Correction: Infection with Soil-Transmitted Helminths Is Associated with Increased Insulin Sensitivity.

Wiria AE, Hamid F, Wammes LJ, Prasetyani MA, Dekkers OM, May L, Kaisar MM, Verweij JJ, Guigas B, Partono F, Sartono E, Supali T, Yazdanbakhsh M, Smit JW.

PLoS One. 2015 Aug 13;10(8):e0136002. doi: 10.1371/journal.pone.0136002. eCollection 2015. No abstract available.

21.

Infection with Soil-Transmitted Helminths Is Associated with Increased Insulin Sensitivity.

Wiria AE, Hamid F, Wammes LJ, Prasetyani MA, Dekkers OM, May L, Kaisar MM, Verweij JJ, Guigas B, Partono F, Sartono E, Supali T, Yazdanbakhsh M, Smit JW.

PLoS One. 2015 Jun 10;10(6):e0127746. doi: 10.1371/journal.pone.0127746. eCollection 2015. Erratum in: PLoS One. 2015;10(8):e0136002.

22.

A worm of one's own: how helminths modulate host adipose tissue function and metabolism.

Guigas B, Molofsky AB.

Trends Parasitol. 2015 Sep;31(9):435-41. doi: 10.1016/j.pt.2015.04.008. Epub 2015 May 16. Review.

23.

Helminth infections and type 2 diabetes: a cluster-randomized placebo controlled SUGARSPIN trial in Nangapanda, Flores, Indonesia.

Tahapary DL, de Ruiter K, Martin I, van Lieshout L, Guigas B, Soewondo P, Djuardi Y, Wiria AE, Mayboroda OA, Houwing-Duistermaat JJ, Tasman H, Sartono E, Yazdanbakhsh M, Smit JW, Supali T.

BMC Infect Dis. 2015 Mar 18;15:133. doi: 10.1186/s12879-015-0873-4.

24.

Chronic helminth infection and helminth-derived egg antigens promote adipose tissue M2 macrophages and improve insulin sensitivity in obese mice.

Hussaarts L, García-Tardón N, van Beek L, Heemskerk MM, Haeberlein S, van der Zon GC, Ozir-Fazalalikhan A, Berbée JF, Willems van Dijk K, van Harmelen V, Yazdanbakhsh M, Guigas B.

FASEB J. 2015 Jul;29(7):3027-39. doi: 10.1096/fj.14-266239. Epub 2015 Apr 7.

PMID:
25852044
25.

Salsalate activates brown adipose tissue in mice.

van Dam AD, Nahon KJ, Kooijman S, van den Berg SM, Kanhai AA, Kikuchi T, Heemskerk MM, van Harmelen V, Lombès M, van den Hoek AM, de Winther MP, Lutgens E, Guigas B, Rensen PC, Boon MR.

Diabetes. 2015 May;64(5):1544-54. doi: 10.2337/db14-1125. Epub 2014 Dec 4.

26.

Metformin: from mechanisms of action to therapies.

Foretz M, Guigas B, Bertrand L, Pollak M, Viollet B.

Cell Metab. 2014 Dec 2;20(6):953-66. doi: 10.1016/j.cmet.2014.09.018. Epub 2014 Oct 30. Review.

27.

Priming dendritic cells for th2 polarization: lessons learned from helminths and implications for metabolic disorders.

Hussaarts L, Yazdanbakhsh M, Guigas B.

Front Immunol. 2014 Oct 20;5:499. doi: 10.3389/fimmu.2014.00499. eCollection 2014. Review.

28.

Middle-aged overweight South Asian men exhibit a different metabolic adaptation to short-term energy restriction compared with Europeans.

Bakker LE, Guigas B, van Schinkel LD, van der Zon GC, Streefland TC, van Klinken JB, Jonker JT, Lamb HJ, Smit JW, Pijl H, Meinders AE, Jazet IM.

Diabetologia. 2015 Jan;58(1):165-77. doi: 10.1007/s00125-014-3408-4. Epub 2014 Oct 15.

PMID:
25316433
29.

Regulation of skeletal muscle energy/nutrient-sensing pathways during metabolic adaptation to fasting in healthy humans.

Wijngaarden MA, Bakker LE, van der Zon GC, 't Hoen PA, van Dijk KW, Jazet IM, Pijl H, Guigas B.

Am J Physiol Endocrinol Metab. 2014 Nov 15;307(10):E885-95. doi: 10.1152/ajpendo.00215.2014. Epub 2014 Sep 23.

30.

Peripheral cannabinoid 1 receptor blockade activates brown adipose tissue and diminishes dyslipidemia and obesity.

Boon MR, Kooijman S, van Dam AD, Pelgrom LR, Berbée JF, Visseren CA, van Aggele RC, van den Hoek AM, Sips HC, Lombès M, Havekes LM, Tamsma JT, Guigas B, Meijer OC, Jukema JW, Rensen PC.

FASEB J. 2014 Dec;28(12):5361-75. doi: 10.1096/fj.13-247643. Epub 2014 Aug 25.

PMID:
25154875
31.

Short-term high-fat diet increases macrophage markers in skeletal muscle accompanied by impaired insulin signalling in healthy male subjects.

Boon MR, Bakker LE, Haks MC, Quinten E, Schaart G, Van Beek L, Wang Y, Van Schinkel L, Van Harmelen V, Meinders AE, Ottenhoff TH, Van Dijk KW, Guigas B, Jazet IM, Rensen PC.

Clin Sci (Lond). 2015 Jan;128(2):143-51. doi: 10.1042/CS20140179.

PMID:
25148551
32.

Sex-specific effects of naturally occurring variants in the dopamine receptor D2 locus on insulin secretion and type 2 diabetes susceptibility.

Guigas B, de Leeuw van Weenen JE, van Leeuwen N, Simonis-Bik AM, van Haeften TW, Nijpels G, Houwing-Duistermaat JJ, Beekman M, Deelen J, Havekes LM, Penninx BW, Vogelzangs N, van 't Riet E, Dehghan A, Hofman A, Witteman JC, Uitterlinden AG, Grarup N, Jørgensen T, Witte DR, Lauritzen T, Hansen T, Pedersen O, Hottenga J, Romijn JA, Diamant M, Kramer MH, Heine RJ, Willemsen G, Dekker JM, Eekhoff EM, Pijl H, de Geus EJ, Slagboom PE, 't Hart LM.

Diabet Med. 2014 Aug;31(8):1001-8. doi: 10.1111/dme.12464. Epub 2014 May 2.

PMID:
24724616
33.

A 5-day high-fat, high-calorie diet impairs insulin sensitivity in healthy, young South Asian men but not in Caucasian men.

Bakker LE, van Schinkel LD, Guigas B, Streefland TC, Jonker JT, van Klinken JB, van der Zon GC, Lamb HJ, Smit JW, Pijl H, Meinders AE, Jazet IM.

Diabetes. 2014 Jan;63(1):248-58. doi: 10.2337/db13-0696.

34.

Metformin lowers plasma triglycerides by promoting VLDL-triglyceride clearance by brown adipose tissue in mice.

Geerling JJ, Boon MR, van der Zon GC, van den Berg SA, van den Hoek AM, Lombès M, Princen HM, Havekes LM, Rensen PC, Guigas B.

Diabetes. 2014 Mar;63(3):880-91. doi: 10.2337/db13-0194. Epub 2013 Nov 22.

35.

CD24(hi)CD27(+) B cells from patients with allergic asthma have impaired regulatory activity in response to lipopolysaccharide.

van der Vlugt LE, Mlejnek E, Ozir-Fazalalikhan A, Janssen Bonas M, Dijksman TR, Labuda LA, Schot R, Guigas B, Möller GM, Hiemstra PS, Yazdanbakhsh M, Smits HH.

Clin Exp Allergy. 2014 Apr;44(4):517-28. doi: 10.1111/cea.12238.

PMID:
24261983
36.

Chronic treatment with olanzapine increases adiposity by changing fuel substrate and causes desensitization of the acute metabolic side effects.

Girault EM, Guigas B, Alkemade A, Foppen E, Ackermans MT, la Fleur SE, Fliers E, Kalsbeek A.

Naunyn Schmiedebergs Arch Pharmacol. 2014 Feb;387(2):185-95. doi: 10.1007/s00210-013-0933-5. Epub 2013 Nov 5.

PMID:
24190543
37.

The insulin sensitizing effect of topiramate involves KATP channel activation in the central nervous system.

Coomans CP, Geerling JJ, van den Berg SA, van Diepen HC, Garcia-Tardón N, Thomas A, Schröder-van der Elst JP, Ouwens DM, Pijl H, Rensen PC, Havekes LM, Guigas B, Romijn JA.

Br J Pharmacol. 2013 Oct;170(4):908-18. doi: 10.1111/bph.12338.

38.

Glucocorticoid treatment impairs microvascular function in healthy men in association with its adverse effects on glucose metabolism and blood pressure: a randomised controlled trial.

van Raalte DH, Diamant M, Ouwens DM, Ijzerman RG, Linssen MM, Guigas B, Eringa EC, Serné EH.

Diabetologia. 2013 Nov;56(11):2383-91. doi: 10.1007/s00125-013-3016-8. Epub 2013 Aug 11.

PMID:
23933953
39.

Rapamycin and omega-1: mTOR-dependent and -independent Th2 skewing by human dendritic cells.

Hussaarts L, Smits HH, Schramm G, van der Ham AJ, van der Zon GC, Haas H, Guigas B, Yazdanbakhsh M.

Immunol Cell Biol. 2013 Aug;91(7):486-9. doi: 10.1038/icb.2013.31. Epub 2013 Jul 9.

PMID:
23835553
40.

Impact of Metformin and compound C on NIS expression and iodine uptake in vitro and in vivo: a role for CRE in AMPK modulation of thyroid function.

Abdulrahman RM, Boon MR, Sips HC, Guigas B, Rensen PC, Smit JW, Hovens GC.

Thyroid. 2014 Jan;24(1):78-87. doi: 10.1089/thy.2013.0041. Epub 2013 Sep 25.

PMID:
23819433
41.

Proline-rich Akt substrate of 40-kDa contains a nuclear export signal.

Wiza C, Nascimento EB, Linssen MM, Carlotti F, Herzfeld de Wiza D, van der Zon GC, Maassen JA, Diamant M, Guigas B, Ouwens DM.

Cell Signal. 2013 Sep;25(9):1762-8. doi: 10.1016/j.cellsig.2013.05.022. Epub 2013 May 24.

PMID:
23712034
42.

The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway.

't Hart LM, Fritsche A, Nijpels G, van Leeuwen N, Donnelly LA, Dekker JM, Alssema M, Fadista J, Carlotti F, Gjesing AP, Palmer CN, van Haeften TW, Herzberg-Schäfer SA, Simonis-Bik AM, Houwing-Duistermaat JJ, Helmer Q, Deelen J, Guigas B, Hansen T, Machicao F, Willemsen G, Heine RJ, Kramer MH, Holst JJ, de Koning EJ, Häring HU, Pedersen O, Groop L, de Geus EJ, Slagboom PE, Boomsma DI, Eekhoff EM, Pearson ER, Diamant M.

Diabetes. 2013 Sep;62(9):3275-81. doi: 10.2337/db13-0227. Epub 2013 May 14.

43.

The degree of liver injury determines the role of p21 in liver regeneration and hepatocarcinogenesis in mice.

Buitrago-Molina LE, Marhenke S, Longerich T, Sharma AD, Boukouris AE, Geffers R, Guigas B, Manns MP, Vogel A.

Hepatology. 2013 Sep;58(3):1143-52. doi: 10.1002/hep.26412. Epub 2013 Aug 7.

PMID:
23526443
44.

Effects of prolonged fasting on AMPK signaling, gene expression, and mitochondrial respiratory chain content in skeletal muscle from lean and obese individuals.

Wijngaarden MA, van der Zon GC, van Dijk KW, Pijl H, Guigas B.

Am J Physiol Endocrinol Metab. 2013 May 1;304(9):E1012-21. doi: 10.1152/ajpendo.00008.2013. Epub 2013 Mar 19.

45.

Prednisolone induces the Wnt signalling pathway in 3T3-L1 adipocytes.

Fleuren WW, Linssen MM, Toonen EJ, van der Zon GC, Guigas B, de Vlieg J, Dokter WH, Ouwens DM, Alkema W.

Arch Physiol Biochem. 2013 May;119(2):52-64. doi: 10.3109/13813455.2013.774022. Epub 2013 Mar 19.

46.

Gene expression analysis of mTOR pathway: association with human longevity.

Passtoors WM, Beekman M, Deelen J, van der Breggen R, Maier AB, Guigas B, Derhovanessian E, van Heemst D, de Craen AJ, Gunn DA, Pawelec G, Slagboom PE.

Aging Cell. 2013 Feb;12(1):24-31. doi: 10.1111/acel.12015. Epub 2012 Nov 23.

47.

A gene variant near ATM is significantly associated with metformin treatment response in type 2 diabetes: a replication and meta-analysis of five cohorts.

van Leeuwen N, Nijpels G, Becker ML, Deshmukh H, Zhou K, Stricker BH, Uitterlinden AG, Hofman A, van 't Riet E, Palmer CN, Guigas B, Slagboom PE, Durrington P, Calle RA, Neil A, Hitman G, Livingstone SJ, Colhoun H, Holman RR, McCarthy MI, Dekker JM, 't Hart LM, Pearson ER.

Diabetologia. 2012 Jul;55(7):1971-7. doi: 10.1007/s00125-012-2537-x. Epub 2012 Mar 28.

48.

AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase.

Bultot L, Guigas B, Von Wilamowitz-Moellendorff A, Maisin L, Vertommen D, Hussain N, Beullens M, Guinovart JJ, Foretz M, Viollet B, Sakamoto K, Hue L, Rider MH.

Biochem J. 2012 Apr 1;443(1):193-203. doi: 10.1042/BJ20112026.

PMID:
22233421
49.

Cellular and molecular mechanisms of metformin: an overview.

Viollet B, Guigas B, Sanz Garcia N, Leclerc J, Foretz M, Andreelli F.

Clin Sci (Lond). 2012 Mar;122(6):253-70. doi: 10.1042/CS20110386. Review.

50.

Stimulatory effect of insulin on glucose uptake by muscle involves the central nervous system in insulin-sensitive mice.

Coomans CP, Biermasz NR, Geerling JJ, Guigas B, Rensen PC, Havekes LM, Romijn JA.

Diabetes. 2011 Dec;60(12):3132-40. doi: 10.2337/db10-1100. Epub 2011 Oct 25.

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