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Items: 7


Agonists and Antagonists of Protease-Activated Receptor 2 Discovered within a DNA-Encoded Chemical Library Using Mutational Stabilization of the Target.

Brown DG, Brown GA, Centrella P, Certel K, Cooke RM, Cuozzo JW, Dekker N, Dumelin CE, Ferguson A, Fiez-Vandal C, Geschwindner S, Guié MA, Habeshian S, Keefe AD, Schlenker O, Sigel EA, Snijder A, Soutter HT, Sundström L, Troast DM, Wiggin G, Zhang J, Zhang Y, Clark MA.

SLAS Discov. 2018 Jun;23(5):429-436. doi: 10.1177/2472555217749847. Epub 2018 Jan 9.


Discovery of cofactor-specific, bactericidal Mycobacterium tuberculosis InhA inhibitors using DNA-encoded library technology.

Soutter HH, Centrella P, Clark MA, Cuozzo JW, Dumelin CE, Guie MA, Habeshian S, Keefe AD, Kennedy KM, Sigel EA, Troast DM, Zhang Y, Ferguson AD, Davies G, Stead ER, Breed J, Madhavapeddi P, Read JA.

Proc Natl Acad Sci U S A. 2016 Dec 6;113(49):E7880-E7889. Epub 2016 Nov 18.


[The study of anticoagulants selection in platelet-rich plasma preparation].

Hua L, Lai G, Zhenjun L, Guie M.

Zhonghua Zheng Xing Wai Ke Za Zhi. 2015 Jul;31(4):295-300. Chinese.


Encoded Library Synthesis Using Chemical Ligation and the Discovery of sEH Inhibitors from a 334-Million Member Library.

Litovchick A, Dumelin CE, Habeshian S, Gikunju D, Guié MA, Centrella P, Zhang Y, Sigel EA, Cuozzo JW, Keefe AD, Clark MA.

Sci Rep. 2015 Jun 10;5:10916. doi: 10.1038/srep10916.


Genome-wide siRNA screen identifies the retromer as a cellular entry factor for human papillomavirus.

Lipovsky A, Popa A, Pimienta G, Wyler M, Bhan A, Kuruvilla L, Guie MA, Poffenberger AC, Nelson CD, Atwood WJ, DiMaio D.

Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7452-7. doi: 10.1073/pnas.1302164110. Epub 2013 Apr 8.


Programs to facilitate tuberculosis drug discovery: the tuberculosis antimicrobial acquisition and coordinating facility.

Goldman RC, Laughon BE, Reynolds RC, Secrist JA 3rd, Maddry JA, Guié MA, Poffenberger AC, Kwong CA, Ananthan S.

Infect Disord Drug Targets. 2007 Jun;7(2):92-104.


Synthesis and preliminary in vitro evaluation of antimycobacterial activity of new pyrrolo[1,2-a] quinoxaline-carboxylic acid hydrazide derivatives.

Guillon J, Reynolds RC, Leger JM, Guie MA, Massip S, Dallemagne P, Jarry C.

J Enzyme Inhib Med Chem. 2004 Dec;19(6):489-95.


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