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Reintroducing Heart Sounds for Early Detection of Acute Myocardial Ischemia in a Porcine Model - Correlation of Acoustic Cardiography With Gold Standard of Pressure-Volume Analysis.

Luciani M, Saccocci M, Kuwata S, Cesarovic N, Lipiski M, Arand P, Bauer P, Guidotti A, Regar E, Erne P, Zuber M, Maisano F.

Front Physiol. 2019 Aug 22;10:1090. doi: 10.3389/fphys.2019.01090. eCollection 2019.


Genome-wide methylation in alcohol use disorder subjects: implications for an epigenetic regulation of the cortico-limbic glucocorticoid receptors (NR3C1).

Gatta E, Grayson DR, Auta J, Saudagar V, Dong E, Chen Y, Krishnan HR, Drnevich J, Pandey SC, Guidotti A.

Mol Psychiatry. 2019 Jun 25. doi: 10.1038/s41380-019-0449-6. [Epub ahead of print]


Transcatheter aortic valve-in-ring implantation: feasibility in an acute, preclinical, pilot trial.

Andreas M, Russo M, Kuwata S, Cesarovic N, Wang C, Guidotti A, Lipiski M, Rankin JS, Regar E, Taramasso M, Maisano F, Weber A.

Interact Cardiovasc Thorac Surg. 2019 Jun 1;28(6):908-915. doi: 10.1093/icvts/ivy341.


Epigenetic Alterations in Prenatal Stress Mice as an Endophenotype Model for Schizophrenia: Role of Metabotropic Glutamate 2/3 Receptors.

Matrisciano F, Dong E, Nicoletti F, Guidotti A.

Front Mol Neurosci. 2018 Nov 30;11:423. doi: 10.3389/fnmol.2018.00423. eCollection 2018. Review.


Long-term analysis of standard abdominal aortic endovascular repair using different grafts focusing on endoleak onset and its evolution.

Chisci E, Guidotti A, Pigozzi C, Frosini P, Sapio PL, Troisi N, Ercolini L, Michelagnoli S.

Int J Cardiol. 2019 Feb 1;276:53-60. doi: 10.1016/j.ijcard.2018.11.009. Epub 2018 Nov 7.


N-Phthalyl-l-Tryptophan (RG108), like Clozapine (CLO), Induces Chromatin Remodeling in Brains of Prenatally Stressed Mice.

Dong E, Locci V, Gatta E, Grayson DR, Guidotti A.

Mol Pharmacol. 2019 Jan;95(1):62-69. doi: 10.1124/mol.118.113415. Epub 2018 Nov 5.


Prenatal stress leads to chromatin and synaptic remodeling and excessive alcohol intake comorbid with anxiety-like behaviors in adult offspring.

Dong E, Guidotti A, Zhang H, Pandey SC.

Neuropharmacology. 2018 Sep 15;140:76-85. doi: 10.1016/j.neuropharm.2018.07.010. Epub 2018 Aug 4.


Potential role for histone deacetylation in chronic diazepam-induced downregulation of α1-GABAA receptor subunit expression.

Auta J, Gatta E, Davis JM, Pandey SC, Guidotti A.

Pharmacol Res Perspect. 2018 Jun 26;6(4):e00416. doi: 10.1002/prp2.416. eCollection 2018 Jul.


DNA Methylation in Animal Models of Psychosis.

Grayson DR, Guidotti A.

Prog Mol Biol Transl Sci. 2018;157:105-132. doi: 10.1016/bs.pmbts.2017.12.012. Epub 2018 Mar 30. Review.


Echocardiographic-fluoroscopic fusion imaging for transcatheter mitral valve repair guidance.

Faletra FF, Pozzoli A, Agricola E, Guidotti A, Biasco L, Leo LA, Taramasso M, Pasotti E, Kuwata S, Moccetti M, Tanner FC, Pedrazzini G, Nietlispach F, Moccetti T, Zuber M, Maisano F.

Eur Heart J Cardiovasc Imaging. 2018 Jul 1;19(7):715-726. doi: 10.1093/ehjci/jey067. Review.


Endovascular Aortic Repair Follow up Protocol Based on Contrast Enhanced Ultrasound Is Safe and Effective.

Chisci E, Harris L, Guidotti A, Pecchioli A, Pigozzi C, Barbanti E, Ercolini L, Michelagnoli S.

Eur J Vasc Endovasc Surg. 2018 Jul;56(1):40-47. doi: 10.1016/j.ejvs.2018.03.006. Epub 2018 Apr 17.


Management of Tricuspid Regurgitation: The Role of Transcatheter Therapies.

Taramasso M, Calen C, Guidotti A, Kuwata S, Biefer HRC, Nietlispach F, Zuber M, Maisano F.

Interv Cardiol. 2017 May;12(1):51-55. doi: 10.15420/icr.2017:3:2.


Drug-coated balloons reduce the risk of recurrent restenosis in arteriovenous fistulas and prosthetic grafts for hemodialysis.

Troisi N, Frosini P, Somma C, Romano E, Guidotti A, Dattolo PC, Ferro G, Chisci E, Michelagnoli S.

Int Angiol. 2018 Feb;37(1):59-63. doi: 10.23736/S0392-9590.17.03886-X. Epub 2017 Nov 10.


Freeway paclitaxel-releasing balloons to treat recurrent stenosis of arteriovenous fistula in hemodialysis patients.

Troisi N, Frosini P, Romano E, Guidotti A, Chisci E, Michelagnoli S.

Minerva Cardioangiol. 2018 Jun;66(3):233-237. doi: 10.23736/S0026-4725.17.04534-0. Epub 2017 Oct 25.


Emerging Role of One-Carbon Metabolism and DNA Methylation Enrichment on δ-Containing GABAA Receptor Expression in the Cerebellum of Subjects with Alcohol Use Disorders (AUD).

Gatta E, Auta J, Gavin DP, Bhaumik DK, Grayson DR, Pandey SC, Guidotti A.

Int J Neuropsychopharmacol. 2017 Dec 1;20(12):1013-1026. doi: 10.1093/ijnp/pyx075.


Fluoroscopic anatomy of the tricuspid valve: Implications for Transcatheter procedures.

Pozzoli A, Maisano F, Kuwata S, Guidotti A, Plass A, Zuber M, Russo M, Nietlispach F, Taramasso M.

Int J Cardiol. 2017 Oct 1;244:119-120. doi: 10.1016/j.ijcard.2017.06.048. Epub 2017 Jun 15. No abstract available.


Ongoing and future directions in percutaneous treatment of mitral regurgitation.

Kuwata S, Taramasso M, Guidotti A, Nietlispach F, Maisano F.

Expert Rev Cardiovasc Ther. 2017 Jun;15(6):441-446. doi: 10.1080/14779072.2017.1327349. Epub 2017 May 19. Review.


Chronic Alcohol Exposure Differentially Alters One-Carbon Metabolism in Rat Liver and Brain.

Auta J, Zhang H, Pandey SC, Guidotti A.

Alcohol Clin Exp Res. 2017 Jun;41(6):1105-1111. doi: 10.1111/acer.13382. Epub 2017 Apr 25.


Successful TriCinch-in-TriCinch Transcatheter Tricuspid Valve Repair.

Calen C, Taramasso M, Guidotti A, Kuwata S, Nietlispach F, Zuber M, Maisano F.

JACC Cardiovasc Interv. 2017 Apr 24;10(8):e75-e77. doi: 10.1016/j.jcin.2017.01.032. Epub 2017 Mar 29. No abstract available.


Evaluation of Valtech's transcatheter mitral valve repair device.

Kuwata S, Taramasso M, Guidotti A, Nietlispach F, Maisano F.

Expert Rev Med Devices. 2017 Mar;14(3):189-195. doi: 10.1080/17434440.2017.1292122. Epub 2017 Feb 20. Review.


Epigenetic regulation of RELN and GAD1 in the frontal cortex (FC) of autism spectrum disorder (ASD) subjects.

Zhubi A, Chen Y, Guidotti A, Grayson DR.

Int J Dev Neurosci. 2017 Nov;62:63-72. doi: 10.1016/j.ijdevneu.2017.02.003. Epub 2017 Feb 14.


Intra-arterial injection of iloprost reduces the risk of early recoil after balloon angioplasty of below-the-knee vessels in patients with critical limb ischemia.

Troisi N, Farina A, Chisci E, Ercolini L, Frosini P, Pigozzi C, Guidotti A, Michelagnoli S.

J Cardiovasc Surg (Torino). 2016 Oct 4. [Epub ahead of print]


The Cardioband: strategies for optimal patient selection and optimised results.

Maisano F, Taramasso M, Guidotti A, Nietlispach F.

EuroIntervention. 2016 Sep 18;12(Y):Y61-3. doi: 10.4244/EIJV12SYA15. Review. No abstract available.


Percutaneous repair of the tricuspid valve using a novel cinching device: acute and chronic experience in a preclinical large animal model.

Taramasso M, Latib A, Denti P, Nietlispach F, Lynn K, Cesarovic N, Addis A, Emmert MY, Guidotti A, Vanermen H, Maisano F.

EuroIntervention. 2016 Sep 18;12(7):918-25. doi: 10.4244/EIJV12I7A150.


Transcatheter direct mitral valve annuloplasty with the Cardioband system for the treatment of functional mitral regurgitation.

Taramasso M, Inderbitzin DT, Guidotti A, Nietlispach F, Gaemperli O, Zuber M, Maisano F.

Multimed Man Cardiothorac Surg. 2016 May 30;2016. pii: mmw004. doi: 10.1093/mmcts/mmw004. Print 2016.


Epigenetic RELN Dysfunction in Schizophrenia and Related Neuropsychiatric Disorders.

Guidotti A, Grayson DR, Caruncho HJ.

Front Cell Neurosci. 2016 Apr 5;10:89. doi: 10.3389/fncel.2016.00089. eCollection 2016. Review.


A creative transcatheter approach to correct complex recurring mitral regurgitation after previous surgical repair.

Czerny M, Taramasso M, Guidotti A, Maisano F.

EuroIntervention. 2016 Feb;11(11):e1302-4. doi: 10.4244/EIJV11I11A252.


Role of Growth Arrest and DNA Damage-Inducible, Beta in Alcohol-Drinking Behaviors.

Gavin DP, Kusumo H, Zhang H, Guidotti A, Pandey SC.

Alcohol Clin Exp Res. 2016 Feb;40(2):263-72. doi: 10.1111/acer.12965.


Metabotropic Glutamate 2/3 Receptors and Epigenetic Modifications in Psychotic Disorders: A Review.

Matrisciano F, Panaccione I, Grayson DR, Nicoletti F, Guidotti A.

Curr Neuropharmacol. 2016;14(1):41-7. Review.


Percutaneous tricuspid valve therapies: the new frontier.

Taramasso M, Pozzoli A, Guidotti A, Nietlispach F, Inderbitzin DT, Benussi S, Alfieri O, Maisano F.

Eur Heart J. 2017 Mar 1;38(9):639-647. doi: 10.1093/eurheartj/ehv766. Review.


Behavioral and molecular neuroepigenetic alterations in prenatally stressed mice: relevance for the study of chromatin remodeling properties of antipsychotic drugs.

Dong E, Tueting P, Matrisciano F, Grayson DR, Guidotti A.

Transl Psychiatry. 2016 Jan 12;6:e711. doi: 10.1038/tp.2015.191.


Varenicline Effects on Smoking, Cognition, and Psychiatric Symptoms in Schizophrenia: A Double-Blind Randomized Trial.

Smith RC, Amiaz R, Si TM, Maayan L, Jin H, Boules S, Sershen H, Li C, Ren J, Liu Y, Youseff M, Lajtha A, Guidotti A, Weiser M, Davis JM.

PLoS One. 2016 Jan 5;11(1):e0143490. doi: 10.1371/journal.pone.0143490. eCollection 2016.


Maternal immune activation induces GAD1 and GAD2 promoter remodeling in the offspring prefrontal cortex.

Labouesse MA, Dong E, Grayson DR, Guidotti A, Meyer U.

Epigenetics. 2015;10(12):1143-55. doi: 10.1080/15592294.2015.1114202.


Transcatheter direct mitral annuloplasty with Cardioband: feasibility and efficacy trial in an acute preclinical model.

Taramasso M, Guidotti A, Cesarovic N, Denti P, Addis A, Candreva A, Nietlispach F, Fleischmann T, Emmert MY, Maisano F.

EuroIntervention. 2016 Dec 10;12(11):e1428-e1434. doi: 10.4244/EIJY15M11_06.


Merging data from genetic and epigenetic approaches to better understand autistic spectrum disorder.

Grayson DR, Guidotti A.

Epigenomics. 2016 Jan;8(1):85-104. doi: 10.2217/epi.15.92. Epub 2015 Nov 9.


Current challenges in interventional mitral valve treatment.

Taramasso M, Candreva A, Pozzoli A, Guidotti A, Gaemperli O, Nietlispach F, Barthelmes J, Emmert MY, Weber A, Benussi S, Alfieri O, Maisano F.

J Thorac Dis. 2015 Sep;7(9):1536-42. doi: 10.3978/j.issn.2072-1439.2015.04.58. Review.


Upper ministernotomy.

Reser D, Holubec T, Scherman J, Yilmaz M, Guidotti A, Maisano F.

Multimed Man Cardiothorac Surg. 2015 Nov 2;2015. pii: mmv036. doi: 10.1093/mmcts/mmv036. Print 2015.


Right lateral mini-thoracotomy for mitral valve surgery.

Reser D, Holubec T, Yilmaz M, Guidotti A, Maisano F.

Multimed Man Cardiothorac Surg. 2015 Oct 26;2015. pii: mmv031. doi: 10.1093/mmcts/mmv031. Print 2015.


Left anterior small thoracotomy for minimally invasive coronary artery bypass grafting.

Reser D, Holubec T, Caliskan E, Guidotti A, Maisano F.

Multimed Man Cardiothorac Surg. 2015 Sep 28;2015. pii: mmv022. doi: 10.1093/mmcts/mmv022. Print 2015.


The Sino Medical AccuFit transcatheter mitral valve implantation system.

Abdelghani M, Onuma Y, Zeng Y, Soliman OI, Ma J, Huo Y, Guidotti A, Nietlispach F, Maisano F, Serruys PW.

EuroIntervention. 2015 Sep;11 Suppl W:W84-5. doi: 10.4244/EIJV11SWA26. No abstract available.


Median sternotomy.

Reser D, Caliskan E, Tolboom H, Guidotti A, Maisano F.

Multimed Man Cardiothorac Surg. 2015 Jul 17;2015. pii: mmv017. doi: 10.1093/mmcts/mmv017. Print 2015.


Gadd45b and N-methyl-D-aspartate induced DNA demethylation in postmitotic neurons.

Gavin DP, Kusumo H, Sharma RP, Guizzetti M, Guidotti A, Pandey SC.

Epigenomics. 2015;7(4):567-79. doi: 10.2217/epi.15.12.


Pre-clinical In Vitro and In Vivo Models for Heart Valve Therapies.

Taramasso M, Emmert MY, Reser D, Guidotti A, Cesarovic N, Campagnol M, Addis A, Nietlispach F, Hoerstrup SP, Maisano F.

J Cardiovasc Transl Res. 2015 Jul;8(5):319-27. doi: 10.1007/s12265-015-9631-7. Epub 2015 May 13.


Clinical and anatomical predictors of MitraClip therapy failure for functional mitral regurgitation: single central clip strategy in asymmetric tethering.

Taramasso M, Denti P, Latib A, Guidotti A, Buzzatti N, Pozzoli A, Di Giannuario G, La Canna G, Colombo A, Alfieri O, Maisano F.

Int J Cardiol. 2015;186:286-8. doi: 10.1016/j.ijcard.2015.03.236. Epub 2015 Mar 18. No abstract available.


Transcatheter mitral repair and replacement: state of the art and future directions.

Buzzatti N, Taramasso M, Latib A, Denti P, Guidotti A, Alfieri O, Maisano F.

J Heart Valve Dis. 2014 Jul;23(4):492-505. Review.


A translational "humanised" porcine model for transcatheter mitral valve interventions: the neo inferior vena cava approach.

Maisano F, Reser D, Pavicevic J, Guidotti A, Denti P, Taramasso M, Addis A, Cesarovic N, Emmert MY, Nietlispach F, Swain J, Falk V, Leon M.

EuroIntervention. 2015 May;11(1):92-5. doi: 10.4244/EIJY15M02_04.


Surgical treatment of paravalvular leak: Long-term results in a single-center experience (up to 14 years).

Taramasso M, Maisano F, Denti P, Guidotti A, Sticchi A, Pozzoli A, Buzzatti N, De Bonis M, La Canna G, Alfieri O.

J Thorac Cardiovasc Surg. 2015 May;149(5):1270-5. doi: 10.1016/j.jtcvs.2014.12.041. Epub 2014 Dec 22.


DNA-methyltransferase1 (DNMT1) binding to CpG rich GABAergic and BDNF promoters is increased in the brain of schizophrenia and bipolar disorder patients.

Dong E, Ruzicka WB, Grayson DR, Guidotti A.

Schizophr Res. 2015 Sep;167(1-3):35-41. doi: 10.1016/j.schres.2014.10.030. Epub 2014 Dec 2.


Brain-derived neurotrophic factor epigenetic modifications associated with schizophrenia-like phenotype induced by prenatal stress in mice.

Dong E, Dzitoyeva SG, Matrisciano F, Tueting P, Grayson DR, Guidotti A.

Biol Psychiatry. 2015 Mar 15;77(6):589-96. doi: 10.1016/j.biopsych.2014.08.012. Epub 2014 Aug 27.


Modeling the molecular epigenetic profile of psychosis in prenatally stressed mice.

Guidotti A, Dong E, Tueting P, Grayson DR.

Prog Mol Biol Transl Sci. 2014;128:89-101. doi: 10.1016/B978-0-12-800977-2.00004-8. Review.

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