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Items: 1 to 50 of 61

1.

Relapse-Fated Latent Diagnosis Subclones in Acute B Lineage Leukemia Are Drug Tolerant and Possess Distinct Metabolic Programs.

Dobson SM, García-Prat L, Vanner RJ, Wintersinger J, Waanders E, Gu Z, McLeod J, Gan OI, Grandal I, Payne-Turner D, Edmonson MN, Ma X, Fan Y, Voisin V, Chan-Seng-Yue M, Xie SZ, Hosseini M, Abelson S, Gupta P, Rusch M, Shao Y, Olsen SR, Neale G, Chan SM, Bader G, Easton J, Guidos CJ, Danska JS, Zhang J, Minden MD, Morris Q, Mullighan CG, Dick JE.

Cancer Discov. 2020 Apr;10(4):568-587. doi: 10.1158/2159-8290.CD-19-1059. Epub 2020 Feb 21.

2.

Validation of CyTOF Against Flow Cytometry for Immunological Studies and Monitoring of Human Cancer Clinical Trials.

Gadalla R, Noamani B, MacLeod BL, Dickson RJ, Guo M, Xu W, Lukhele S, Elsaesser HJ, Razak ARA, Hirano N, McGaha TL, Wang B, Butler M, Guidos CJ, Ohashi PS, Siu LL, Brooks DG.

Front Oncol. 2019 May 17;9:415. doi: 10.3389/fonc.2019.00415. eCollection 2019.

3.

Method for Tagging Antibodies with Metals for Mass Cytometry Experiments.

Chang SG, Guidos CJ.

Methods Mol Biol. 2019;1989:47-54. doi: 10.1007/978-1-4939-9454-0_4.

PMID:
31077098
4.

Cdh1 and Pik3ca Mutations Cooperate to Induce Immune-Related Invasive Lobular Carcinoma of the Breast.

An Y, Adams JR, Hollern DP, Zhao A, Chang SG, Gams MS, Chung PED, He X, Jangra R, Shah JS, Yang J, Beck LA, Raghuram N, Kozma KJ, Loch AJ, Wang W, Fan C, Done SJ, Zacksenhaus E, Guidos CJ, Perou CM, Egan SE.

Cell Rep. 2018 Oct 16;25(3):702-714.e6. doi: 10.1016/j.celrep.2018.09.056.

5.

CD8+ T Cell Priming in Established Chronic Viral Infection Preferentially Directs Differentiation of Memory-like Cells for Sustained Immunity.

Snell LM, MacLeod BL, Law JC, Osokine I, Elsaesser HJ, Hezaveh K, Dickson RJ, Gavin MA, Guidos CJ, McGaha TL, Brooks DG.

Immunity. 2018 Oct 16;49(4):678-694.e5. doi: 10.1016/j.immuni.2018.08.002. Epub 2018 Oct 9.

6.

Regulatory T Cells in Ovarian Cancer Are Characterized by a Highly Activated Phenotype Distinct from that in Melanoma.

Toker A, Nguyen LT, Stone SC, Yang SYC, Katz SR, Shaw PA, Clarke BA, Ghazarian D, Al-Habeeb A, Easson A, Leong WL, McCready DR, Reedijk M, Guidos CJ, Pugh TJ, Bernardini MQ, Ohashi PS.

Clin Cancer Res. 2018 Nov 15;24(22):5685-5696. doi: 10.1158/1078-0432.CCR-18-0554. Epub 2018 Jul 31.

7.

Functional screening of FGFR4-driven tumorigenesis identifies PI3K/mTOR inhibition as a therapeutic strategy in rhabdomyosarcoma.

McKinnon T, Venier R, Yohe M, Sindiri S, Gryder BE, Shern JF, Kabaroff L, Dickson B, Schleicher K, Chouinard-Pelletier G, Menezes S, Gupta A, Zhang X, Guha R, Ferrer M, Thomas CJ, Wei Y, Davani D, Guidos CJ, Khan J, Gladdy RA.

Oncogene. 2018 May;37(20):2630-2644. doi: 10.1038/s41388-017-0122-y. Epub 2018 Feb 28.

PMID:
29487419
8.

A key role for IL-7R in the generation of microenvironments required for thymic dendritic cells.

Moore AJ, In TS, Trotman-Grant A, Yoganathan K, Montpellier B, Guidos CJ, Zúñiga-Pflücker JC, Anderson MK.

Immunol Cell Biol. 2017 Nov;95(10):933-942. doi: 10.1038/icb.2017.74. Epub 2017 Sep 11.

9.

Chemo-genomic interrogation of CEBPA mutated AML reveals recurrent CSF3R mutations and subgroup sensitivity to JAK inhibitors.

Lavallée VP, Krosl J, Lemieux S, Boucher G, Gendron P, Pabst C, Boivin I, Marinier A, Guidos CJ, Meloche S, Hébert J, Sauvageau G.

Blood. 2016 Jun 16;127(24):3054-61. doi: 10.1182/blood-2016-03-705053. Epub 2016 Mar 31.

PMID:
27034432
10.

Corrigendum: Notch signal strength controls cell fate in the haemogenic endothelium.

Gama-Norton L, Ferrando E, Ruiz-Herguido C, Liu Z, Guiu J, Islam AB, Lee SU, Yan M, Guidos CJ, López-Bigas N, Maeda T, Espinosa L, Kopan R, Bigas A.

Nat Commun. 2016 Mar 4;7:10978. doi: 10.1038/ncomms10978. No abstract available.

11.

Notch signal strength controls cell fate in the haemogenic endothelium.

Gama-Norton L, Ferrando E, Ruiz-Herguido C, Liu Z, Guiu J, Islam AB, Lee SU, Yan M, Guidos CJ, López-Bigas N, Maeda T, Espinosa L, Kopan R, Bigas A.

Nat Commun. 2015 Oct 14;6:8510. doi: 10.1038/ncomms9510. Erratum in: Nat Commun. 2016;7:10978. Liu, Zenhy [Corrected to Liu, Zhenyi].

12.

In Vivo Senescence in the Sbds-Deficient Murine Pancreas: Cell-Type Specific Consequences of Translation Insufficiency.

Tourlakis ME, Zhang S, Ball HL, Gandhi R, Liu H, Zhong J, Yuan JS, Guidos CJ, Durie PR, Rommens JM.

PLoS Genet. 2015 Jun 9;11(6):e1005288. doi: 10.1371/journal.pgen.1005288. eCollection 2015 Jun.

13.

IL-7 coordinates proliferation, differentiation and Tcra recombination during thymocyte β-selection.

Boudil A, Matei IR, Shih HY, Bogdanoski G, Yuan JS, Chang SG, Montpellier B, Kowalski PE, Voisin V, Bashir S, Bader GD, Krangel MS, Guidos CJ.

Nat Immunol. 2015 Apr;16(4):397-405. doi: 10.1038/ni.3122. Epub 2015 Mar 2.

14.

Cell surface profiling using high-throughput flow cytometry: a platform for biomarker discovery and analysis of cellular heterogeneity.

Gedye CA, Hussain A, Paterson J, Smrke A, Saini H, Sirskyj D, Pereira K, Lobo N, Stewart J, Go C, Ho J, Medrano M, Hyatt E, Yuan J, Lauriault S, Meyer M, Kondratyev M, van den Beucken T, Jewett M, Dirks P, Guidos CJ, Danska J, Wang J, Wouters B, Neel B, Rottapel R, Ailles LE.

PLoS One. 2014 Aug 29;9(8):e105602. doi: 10.1371/journal.pone.0105602. eCollection 2014. Erratum in: PLoS One. 2014;9(11):e114354. Meyer, Mona [added].

15.

MuLV-related endogenous retroviral elements and Flt3 participate in aberrant end-joining events that promote B-cell leukemogenesis.

Johnson RM, Papp E, Grandal I, Kowalski PE, Nutter L, Wong RC, Joseph-George AM, Danska JS, Guidos CJ.

Genes Dev. 2014 Jun 1;28(11):1179-90. doi: 10.1101/gad.240820.114.

16.

Therapeutic potential of spleen tyrosine kinase inhibition for treating high-risk precursor B cell acute lymphoblastic leukemia.

Perova T, Grandal I, Nutter LM, Papp E, Matei IR, Beyene J, Kowalski PE, Hitzler JK, Minden MD, Guidos CJ, Danska JS.

Sci Transl Med. 2014 May 14;6(236):236ra62. doi: 10.1126/scitranslmed.3008661.

17.

Dominant-negative Ikaros cooperates with BCR-ABL1 to induce human acute myeloid leukemia in xenografts.

Theocharides AP, Dobson SM, Laurenti E, Notta F, Voisin V, Cheng PY, Yuan JS, Guidos CJ, Minden MD, Mullighan CG, Torlakovic E, Dick JE.

Leukemia. 2015 Jan;29(1):177-87. doi: 10.1038/leu.2014.150. Epub 2014 May 5.

PMID:
24791856
18.

STAT5-induced lunatic fringe during Th2 development alters delta-like 4-mediated Th2 cytokine production in respiratory syncytial virus-exacerbated airway allergic disease.

Mukherjee S, Rasky AJ, Lundy PA, Kittan NA, Kunkel SL, Maillard IP, Kowalski PE, Kousis PC, Guidos CJ, Lukacs NW.

J Immunol. 2014 Feb 1;192(3):996-1003. doi: 10.4049/jimmunol.1301991. Epub 2013 Dec 23.

19.

Notch2-dependent classical dendritic cells orchestrate intestinal immunity to attaching-and-effacing bacterial pathogens.

Satpathy AT, Briseño CG, Lee JS, Ng D, Manieri NA, Kc W, Wu X, Thomas SR, Lee WL, Turkoz M, McDonald KG, Meredith MM, Song C, Guidos CJ, Newberry RD, Ouyang W, Murphy TL, Stappenbeck TS, Gommerman JL, Nussenzweig MC, Colonna M, Kopan R, Murphy KM.

Nat Immunol. 2013 Sep;14(9):937-48. doi: 10.1038/ni.2679. Epub 2013 Aug 4.

20.

Lunatic fringe deficiency cooperates with the Met/Caveolin gene amplicon to induce basal-like breast cancer.

Xu K, Usary J, Kousis PC, Prat A, Wang DY, Adams JR, Wang W, Loch AJ, Deng T, Zhao W, Cardiff RD, Yoon K, Gaiano N, Ling V, Beyene J, Zacksenhaus E, Gridley T, Leong WL, Guidos CJ, Perou CM, Egan SE.

Cancer Cell. 2012 May 15;21(5):626-41. doi: 10.1016/j.ccr.2012.03.041.

21.

Zebrafish screen identifies novel compound with selective toxicity against leukemia.

Ridges S, Heaton WL, Joshi D, Choi H, Eiring A, Batchelor L, Choudhry P, Manos EJ, Sofla H, Sanati A, Welborn S, Agarwal A, Spangrude GJ, Miles RR, Cox JE, Frazer JK, Deininger M, Balan K, Sigman M, Müschen M, Perova T, Johnson R, Montpellier B, Guidos CJ, Jones DA, Trede NS.

Blood. 2012 Jun 14;119(24):5621-31. doi: 10.1182/blood-2011-12-398818. Epub 2012 Apr 9.

22.

Proteomic analyses reveal high expression of decorin and endoplasmin (HSP90B1) are associated with breast cancer metastasis and decreased survival.

Cawthorn TR, Moreno JC, Dharsee M, Tran-Thanh D, Ackloo S, Zhu PH, Sardana G, Chen J, Kupchak P, Jacks LM, Miller NA, Youngson BJ, Iakovlev V, Guidos CJ, Vallis KA, Evans KR, McCready D, Leong WL, Done SJ.

PLoS One. 2012;7(2):e30992. doi: 10.1371/journal.pone.0030992. Epub 2012 Feb 20.

23.

Jagged2 acts as a Delta-like Notch ligand during early hematopoietic cell fate decisions.

Van de Walle I, De Smet G, Gärtner M, De Smedt M, Waegemans E, Vandekerckhove B, Leclercq G, Plum J, Aster JC, Bernstein ID, Guidos CJ, Kyewski B, Taghon T.

Blood. 2011 Apr 28;117(17):4449-59. doi: 10.1182/blood-2010-06-290049. Epub 2011 Mar 3.

24.

Lunatic Fringe prolongs Delta/Notch-induced self-renewal of committed αβ T-cell progenitors.

Yuan JS, Tan JB, Visan I, Matei IR, Urbanellis P, Xu K, Danska JS, Egan SE, Guidos CJ.

Blood. 2011 Jan 27;117(4):1184-95. doi: 10.1182/blood-2010-07-296616. Epub 2010 Nov 19.

PMID:
21097675
25.

Lunatic fringe enhances competition for delta-like Notch ligands but does not overcome defective pre-TCR signaling during thymocyte beta-selection in vivo.

Visan I, Yuan JS, Liu Y, Stanley P, Guidos CJ.

J Immunol. 2010 Oct 15;185(8):4609-17. doi: 10.4049/jimmunol.1002008. Epub 2010 Sep 15.

26.

Functions of notch signaling in the immune system: consensus and controversies.

Yuan JS, Kousis PC, Suliman S, Visan I, Guidos CJ.

Annu Rev Immunol. 2010;28:343-65. doi: 10.1146/annurev.immunol.021908.132719. Review.

PMID:
20192807
27.

Regulation of Notch signaling during T- and B-cell development by O-fucose glycans.

Stanley P, Guidos CJ.

Immunol Rev. 2009 Jul;230(1):201-15. doi: 10.1111/j.1600-065X.2009.00791.x. Review.

PMID:
19594638
28.

Lunatic and manic fringe cooperatively enhance marginal zone B cell precursor competition for delta-like 1 in splenic endothelial niches.

Tan JB, Xu K, Cretegny K, Visan I, Yuan JS, Egan SE, Guidos CJ.

Immunity. 2009 Feb 20;30(2):254-63. doi: 10.1016/j.immuni.2008.12.016. Epub 2009 Feb 12.

29.

Chromosomal reinsertion of broken RSS ends during T cell development.

Curry JD, Schulz D, Guidos CJ, Danska JS, Nutter L, Nussenzweig A, Schlissel MS.

J Exp Med. 2007 Oct 1;204(10):2293-303. Epub 2007 Sep 4.

30.

ATM deficiency disrupts Tcra locus integrity and the maturation of CD4+CD8+ thymocytes.

Matei IR, Gladdy RA, Nutter LM, Canty A, Guidos CJ, Danska JS.

Blood. 2007 Mar 1;109(5):1887-96. Epub 2006 Oct 31.

PMID:
17077325
31.

Synergy between the pre-T cell receptor and Notch: cementing the alphabeta lineage choice.

Guidos CJ.

J Exp Med. 2006 Oct 2;203(10):2233-7. Epub 2006 Sep 25. Review.

32.

Regulation of T lymphopoiesis by Notch1 and Lunatic fringe-mediated competition for intrathymic niches.

Visan I, Tan JB, Yuan JS, Harper JA, Koch U, Guidos CJ.

Nat Immunol. 2006 Jun;7(6):634-43. Epub 2006 May 14.

PMID:
16699526
33.

p53-Independent apoptosis disrupts early organogenesis in embryos lacking both ataxia-telangiectasia mutated and Prkdc.

Gladdy RA, Nutter LM, Kunath T, Danska JS, Guidos CJ.

Mol Cancer Res. 2006 May;4(5):311-8.

34.

ATM-dependent DNA damage surveillance in T-cell development and leukemogenesis: the DSB connection.

Matei IR, Guidos CJ, Danska JS.

Immunol Rev. 2006 Feb;209:142-58. Review.

PMID:
16448540
35.

Regulation of intrathymic T-cell development by Lunatic Fringe- Notch1 interactions.

Visan I, Yuan JS, Tan JB, Cretegny K, Guidos CJ.

Immunol Rev. 2006 Feb;209:76-94. Review.

PMID:
16448535
36.

Requirement for Notch1 signals at sequential early stages of intrathymic T cell development.

Tan JB, Visan I, Yuan JS, Guidos CJ.

Nat Immunol. 2005 Jul;6(7):671-9. Epub 2005 Jun 12. Erratum in: Nat Immunol. 2005 Sep;6(9):954.

PMID:
15951812
37.

Notch signaling in development and disease.

Harper JA, Yuan JS, Tan JB, Visan I, Guidos CJ.

Clin Genet. 2003 Dec;64(6):461-72. Review.

PMID:
14986825
38.

Fine-tuning Notch1 activation by endocytosis and glycosylation.

Koch U, Yuan JS, Harper JA, Guidos CJ.

Semin Immunol. 2003 Apr;15(2):99-106. Review.

PMID:
12681946
39.

The RAG-1/2 endonuclease causes genomic instability and controls CNS complications of lymphoblastic leukemia in p53/Prkdc-deficient mice.

Gladdy RA, Taylor MD, Williams CJ, Grandal I, Karaskova J, Squire JA, Rutka JT, Guidos CJ, Danska JS.

Cancer Cell. 2003 Jan;3(1):37-50.

40.

Notch signaling in lymphocyte development.

Guidos CJ.

Semin Immunol. 2002 Dec;14(6):395-404. Review.

PMID:
12457612
41.

Transgenic expression of numb inhibits notch signaling in immature thymocytes but does not alter T cell fate specification.

French MB, Koch U, Shaye RE, McGill MA, Dho SE, Guidos CJ, McGlade CJ.

J Immunol. 2002 Apr 1;168(7):3173-80.

42.

Subversion of the T/B lineage decision in the thymus by lunatic fringe-mediated inhibition of Notch-1.

Koch U, Lacombe TA, Holland D, Bowman JL, Cohen BL, Egan SE, Guidos CJ.

Immunity. 2001 Aug;15(2):225-36.

43.

Irradiation promotes V(D)J joining and RAG-dependent neoplastic transformation in SCID T-cell precursors.

Williams CJ, Grandal I, Vesprini DJ, Wojtyra U, Danska JS, Guidos CJ.

Mol Cell Biol. 2001 Jan;21(2):400-13.

44.
45.

Essential and perilous: V(D)J recombination and DNA damage checkpoints in lymphocyte precursors.

Danska JS, Guidos CJ.

Semin Immunol. 1997 Jun;9(3):199-206. Review.

PMID:
9200331
46.

TCR engagement of CD4+CD8+ thymocytes in vitro induces early aspects of positive selection, but not apoptosis.

Groves T, Parsons M, Miyamoto NG, Guidos CJ.

J Immunol. 1997 Jan 1;158(1):65-75.

PMID:
8977176
47.

Fyn can partially substitute for Lck in T lymphocyte development.

Groves T, Smiley P, Cooke MP, Forbush K, Perlmutter RM, Guidos CJ.

Immunity. 1996 Nov;5(5):417-28.

48.

Biochemical and genetic defects in the DNA-dependent protein kinase in murine scid lymphocytes.

Danska JS, Holland DP, Mariathasan S, Williams KM, Guidos CJ.

Mol Cell Biol. 1996 Oct;16(10):5507-17.

49.

V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors.

Guidos CJ, Williams CJ, Grandal I, Knowles G, Huang MT, Danska JS.

Genes Dev. 1996 Aug 15;10(16):2038-54.

50.

Transient restoration of gene rearrangement at multiple T cell receptor loci in gamma-irradiated scid mice.

Livák F, Welsh SC, Guidos CJ, Crispe IN, Danska JS, Schatz DG.

J Exp Med. 1996 Aug 1;184(2):419-28.

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