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Items: 49

1.

Metformin promotes anxiolytic and antidepressant-like responses in insulin-resistant mice by decreasing circulating branched-chain amino acids.

Zemdegs J, Martin H, Pintana H, Bullich S, Manta S, Marqués MA, Moro C, Layé S, Ducrocq F, Chattipakorn N, Chattipakorn SC, Rampon C, Pénicaud L, Fioramonti X, Guiard BP.

J Neurosci. 2019 Jun 3. pii: 2904-18. doi: 10.1523/JNEUROSCI.2904-18.2019. [Epub ahead of print]

PMID:
31160539
2.

Lack of correlation between the activity of the mesolimbic dopaminergic system and the rewarding properties of pregabalin in mouse.

Coutens B, Mouledous L, Stella M, Rampon C, Lapeyre-Mestre M, Roussin A, Guiard BP, Jouanjus E.

Psychopharmacology (Berl). 2019 Jul;236(7):2069-2082. doi: 10.1007/s00213-019-05198-z. Epub 2019 Mar 16.

PMID:
30879119
3.

Viral vector-mediated Cre recombinase expression in substantia nigra induces lesions of the nigrostriatal pathway associated with perturbations of dopamine-related behaviors and hallmarks of programmed cell death.

Rezai Amin S, Gruszczynski C, Guiard BP, Callebert J, Launay JM, Louis F, Betancur C, Vialou V, Gautron S.

J Neurochem. 2019 Feb 12. doi: 10.1111/jnc.14684. [Epub ahead of print]

PMID:
30748001
4.

Anxiolytic- and Antidepressant-Like Effects of Fish Oil-Enriched Diet in Brain-Derived Neurotrophic Factor Deficient Mice.

Zemdegs J, Rainer Q, Grossmann CP, Rousseau-Ralliard D, Grynberg A, Ribeiro E, Guiard BP.

Front Neurosci. 2018 Dec 21;12:974. doi: 10.3389/fnins.2018.00974. eCollection 2018.

5.

Positive regulation of raphe serotonin neurons by serotonin 2B receptors.

Belmer A, Quentin E, Diaz SL, Guiard BP, Fernandez SP, Doly S, Banas SM, Pitychoutis PM, Moutkine I, Muzerelle A, Tchenio A, Roumier A, Mameli M, Maroteaux L.

Neuropsychopharmacology. 2018 Jun;43(7):1623-1632. doi: 10.1038/s41386-018-0013-0. Epub 2018 Feb 5.

6.

Differential alteration of hippocampal function and plasticity in females and males of the APPxPS1 mouse model of Alzheimer's disease.

Richetin K, Petsophonsakul P, Roybon L, Guiard BP, Rampon C.

Neurobiol Aging. 2017 Sep;57:220-231. doi: 10.1016/j.neurobiolaging.2017.05.025. Epub 2017 Jun 6.

PMID:
28666707
7.

Heterodimers of serotonin receptor subtypes 2 are driven by 5-HT2C protomers.

Moutkine I, Quentin E, Guiard BP, Maroteaux L, Doly S.

J Biol Chem. 2017 Apr 14;292(15):6352-6368. doi: 10.1074/jbc.M117.779041. Epub 2017 Mar 3.

8.

Serotonin Signaling through Prefrontal Cortex 5-HT1A Receptors during Adolescence Can Determine Baseline Mood-Related Behaviors.

Garcia-Garcia AL, Meng Q, Canetta S, Gardier AM, Guiard BP, Kellendonk C, Dranovsky A, Leonardo ED.

Cell Rep. 2017 Jan 31;18(5):1144-1156. doi: 10.1016/j.celrep.2017.01.021.

9.

Ketamine treatment involves medial prefrontal cortex serotonin to induce a rapid antidepressant-like activity in BALB/cJ mice.

Pham TH, Mendez-David I, Defaix C, Guiard BP, Tritschler L, David DJ, Gardier AM.

Neuropharmacology. 2017 Jan;112(Pt A):198-209. doi: 10.1016/j.neuropharm.2016.05.010. Epub 2016 May 17.

PMID:
27211253
10.

Genetic dysfunction of serotonin 2A receptor hampers response to antidepressant drugs: A translational approach.

Qesseveur G, Petit AC, Nguyen HT, Dahan L, Colle R, Rotenberg S, Seif I, Robert P, David D, Guilloux JP, Gardier AM, Verstuyft C, Becquemont L, Corruble E, Guiard BP.

Neuropharmacology. 2016 Jun;105:142-153. doi: 10.1016/j.neuropharm.2015.12.022. Epub 2016 Jan 4.

PMID:
26764241
11.

Attenuated Levels of Hippocampal Connexin 43 and its Phosphorylation Correlate with Antidepressant- and Anxiolytic-Like Activities in Mice.

Quesseveur G, Portal B, Basile JA, Ezan P, Mathou A, Halley H, Leloup C, Fioramonti X, Déglon N, Giaume C, Rampon C, Guiard BP.

Front Cell Neurosci. 2015 Dec 22;9:490. doi: 10.3389/fncel.2015.00490. eCollection 2015.

12.

High-fat diet-induced metabolic disorders impairs 5-HT function and anxiety-like behavior in mice.

Zemdegs J, Quesseveur G, Jarriault D, Pénicaud L, Fioramonti X, Guiard BP.

Br J Pharmacol. 2016 Jul;173(13):2095-110. doi: 10.1111/bph.13343. Epub 2015 Dec 9.

13.

Central serotonin-2A (5-HT2A) receptor dysfunction in depression and epilepsy: the missing link?

Guiard BP, Di Giovanni G.

Front Pharmacol. 2015 Mar 17;6:46. doi: 10.3389/fphar.2015.00046. eCollection 2015. Review.

14.

Antinociceptive activity of the new triple reuptake inhibitor NS18283 in a mouse model of chemotherapy-induced neuropathic pain.

Hache G, Guiard BP, Nguyen TH, Quesseveur G, Gardier AM, Peters D, Munro G, Coudoré F.

Eur J Pain. 2015 Mar;19(3):322-33. doi: 10.1002/ejp.550.

PMID:
25045036
15.

NREM sleep hypersomnia and reduced sleep/wake continuity in a neuroendocrine mouse model of anxiety/depression based on chronic corticosterone administration.

Le Dantec Y, Hache G, Guilloux JP, Guiard BP, David DJ, Adrien J, Escourrou P.

Neuroscience. 2014 Aug 22;274:357-68. doi: 10.1016/j.neuroscience.2014.05.050. Epub 2014 Jun 6.

PMID:
24909899
16.

Converging translational evidence for the involvement of the serotonin 2A receptor gene in major depressive disorder.

Petit AC, Quesseveur G, Gressier F, Colle R, David DJ, Gardier AM, Ferreri F, Lépine JP, Falissard B, Verstuyft C, Guiard BP, Corruble E.

Prog Neuropsychopharmacol Biol Psychiatry. 2014 Oct 3;54:76-82. doi: 10.1016/j.pnpbp.2014.04.013. Epub 2014 May 5.

PMID:
24801750
17.

The monoaminergic tripartite synapse: a putative target for currently available antidepressant drugs.

Quesseveur G, Gardier AM, Guiard BP.

Curr Drug Targets. 2013 Oct;14(11):1277-94. Review.

PMID:
24020973
18.

Antidepressant and anxiolytic potential of the multimodal antidepressant vortioxetine (Lu AA21004) assessed by behavioural and neurogenesis outcomes in mice.

Guilloux JP, Mendez-David I, Pehrson A, Guiard BP, Repérant C, Orvoën S, Gardier AM, Hen R, Ebert B, Miller S, Sanchez C, David DJ.

Neuropharmacology. 2013 Oct;73:147-59. doi: 10.1016/j.neuropharm.2013.05.014. Epub 2013 May 28.

19.

BDNF overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities.

Quesseveur G, David DJ, Gaillard MC, Pla P, Wu MV, Nguyen HT, Nicolas V, Auregan G, David I, Dranovsky A, Hantraye P, Hen R, Gardier AM, Déglon N, Guiard BP.

Transl Psychiatry. 2013 Apr 30;3:e253. doi: 10.1038/tp.2013.30.

20.

5-HT₂A receptor inactivation potentiates the acute antidepressant-like activity of escitalopram: involvement of the noradrenergic system.

Quesseveur G, Repérant C, David DJ, Gardier AM, Sanchez C, Guiard BP.

Exp Brain Res. 2013 Apr;226(2):285-95. doi: 10.1007/s00221-013-3434-3. Epub 2013 Feb 15.

PMID:
23411676
21.

5-HT2 ligands in the treatment of anxiety and depression.

Quesseveur G, Nguyen HT, Gardier AM, Guiard BP.

Expert Opin Investig Drugs. 2012 Nov;21(11):1701-25. doi: 10.1517/13543784.2012.719872. Epub 2012 Aug 24. Review.

PMID:
22917059
22.

Antinociceptive effects of fluoxetine in a mouse model of anxiety/depression.

Hache G, Guiard BP, Le Dantec Y, Orvoën S, David DJ, Gardier AM, Coudoré F.

Neuroreport. 2012 Jun 20;23(9):525-9. doi: 10.1097/WNR.0b013e328353d70a.

PMID:
22555563
23.

Blockade of the high-affinity noradrenaline transporter (NET) by the selective 5-HT reuptake inhibitor escitalopram: an in vivo microdialysis study in mice.

Nguyen HT, Guiard BP, Bacq A, David DJ, David I, Quesseveur G, Gautron S, Sanchez C, Gardier AM.

Br J Pharmacol. 2013 Jan;168(1):103-16. doi: 10.1111/j.1476-5381.2012.01850.x.

24.

Functional status of somatodendritic serotonin 1A autoreceptor after long-term treatment with fluoxetine in a mouse model of anxiety/depression based on repeated corticosterone administration.

Rainer Q, Nguyen HT, Quesseveur G, Gardier AM, David DJ, Guiard BP.

Mol Pharmacol. 2012 Feb;81(2):106-12. doi: 10.1124/mol.111.075796. Epub 2011 Oct 26.

PMID:
22031471
25.

Serotonin-1A autoreceptors are necessary and sufficient for the normal formation of circuits underlying innate anxiety.

Richardson-Jones JW, Craige CP, Nguyen TH, Kung HF, Gardier AM, Dranovsky A, David DJ, Guiard BP, Beck SG, Hen R, Leonardo ED.

J Neurosci. 2011 Apr 20;31(16):6008-18. doi: 10.1523/JNEUROSCI.5836-10.2011.

26.

Altered response to the selective serotonin reuptake inhibitor escitalopram in mice heterozygous for the serotonin transporter: an electrophysiological and neurochemical study.

Guiard BP, Mansari ME, Murphy DL, Blier P.

Int J Neuropsychopharmacol. 2012 Apr;15(3):349-61. doi: 10.1017/S1461145711000484. Epub 2011 Mar 25.

PMID:
21439106
27.

Characterization of 5-HT(1A/1B)-/- mice: an animal model sensitive to anxiolytic treatments.

Guilloux JP, David DJ, Xia L, Nguyen HT, Rainer Q, Guiard BP, Repérant C, Deltheil T, Toth M, Hen R, Gardier AM.

Neuropharmacology. 2011 Sep;61(3):478-88. doi: 10.1016/j.neuropharm.2011.02.009. Epub 2011 Feb 17.

PMID:
21333660
28.

Glucocorticoid receptors in dopaminoceptive neurons, key for cocaine, are dispensable for molecular and behavioral morphine responses.

Barik J, Parnaudeau S, Saint Amaux AL, Guiard BP, Golib Dzib JF, Bocquet O, Bailly A, Benecke A, Tronche F.

Biol Psychiatry. 2010 Aug 1;68(3):231-9. doi: 10.1016/j.biopsych.2010.03.037. Epub 2010 Jun 15.

PMID:
20554270
29.

Relevance of norepinephrine-dopamine interactions in the treatment of major depressive disorder.

El Mansari M, Guiard BP, Chernoloz O, Ghanbari R, Katz N, Blier P.

CNS Neurosci Ther. 2010 Jun;16(3):e1-17. doi: 10.1111/j.1755-5949.2010.00146.x. Epub 2010 Apr 8. Review.

30.

5-HT1A autoreceptor levels determine vulnerability to stress and response to antidepressants.

Richardson-Jones JW, Craige CP, Guiard BP, Stephen A, Metzger KL, Kung HF, Gardier AM, Dranovsky A, David DJ, Beck SG, Hen R, Leonardo ED.

Neuron. 2010 Jan 14;65(1):40-52. doi: 10.1016/j.neuron.2009.12.003.

31.

Characterization of the electrophysiological properties of triple reuptake inhibitors on monoaminergic neurons.

Guiard BP, Chenu F, El Mansari M, Blier P.

Int J Neuropsychopharmacol. 2011 Mar;14(2):211-23. doi: 10.1017/S1461145710000076. Epub 2010 Feb 11.

PMID:
20149268
32.

A longitudinal study of 5-HT outflow during chronic fluoxetine treatment using a new technique of chronic microdialysis in a highly emotional mouse strain.

Popa D, Cerdan J, Repérant C, Guiard BP, Guilloux JP, David DJ, Gardier AM.

Eur J Pharmacol. 2010 Feb 25;628(1-3):83-90. doi: 10.1016/j.ejphar.2009.11.037. Epub 2009 Nov 26.

PMID:
19944680
33.

Effects of acute and sustained administration of the catecholamine reuptake inhibitor nomifensine on the firing activity of monoaminergic neurons.

Katz NS, Guiard BP, El Mansari M, Blier P.

J Psychopharmacol. 2010 Aug;24(8):1223-35. doi: 10.1177/0269881109348178. Epub 2009 Nov 25.

PMID:
19939862
34.

Prospect of a dopamine contribution in the next generation of antidepressant drugs: the triple reuptake inhibitors.

Guiard BP, El Mansari M, Blier P.

Curr Drug Targets. 2009 Nov;10(11):1069-84. Review.

PMID:
19702555
35.

Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression.

David DJ, Samuels BA, Rainer Q, Wang JW, Marsteller D, Mendez I, Drew M, Craig DA, Guiard BP, Guilloux JP, Artymyshyn RP, Gardier AM, Gerald C, Antonijevic IA, Leonardo ED, Hen R.

Neuron. 2009 May 28;62(4):479-93. doi: 10.1016/j.neuron.2009.04.017.

36.

Interest of using genetically manipulated mice as models of depression to evaluate antidepressant drugs activity: a review.

Gardier AM, Guiard BP, Guilloux JP, Repérant C, Coudoré F, David DJ.

Fundam Clin Pharmacol. 2009 Feb;23(1):23-42. doi: 10.1111/j.1472-8206.2008.00640.x. Review.

PMID:
19267769
37.

Behavioral and serotonergic consequences of decreasing or increasing hippocampus brain-derived neurotrophic factor protein levels in mice.

Deltheil T, Guiard BP, Cerdan J, David DJ, Tanaka KF, Repérant C, Guilloux JP, Coudoré F, Hen R, Gardier AM.

Neuropharmacology. 2008 Nov;55(6):1006-14. doi: 10.1016/j.neuropharm.2008.08.001. Epub 2008 Aug 12. Review.

PMID:
18761360
38.

Cross-talk between dopaminergic and noradrenergic systems in the rat ventral tegmental area, locus ceruleus, and dorsal hippocampus.

Guiard BP, El Mansari M, Blier P.

Mol Pharmacol. 2008 Nov;74(5):1463-75. doi: 10.1124/mol.108.048033. Epub 2008 Aug 14.

PMID:
18703671
39.

Functional interactions between dopamine, serotonin and norepinephrine neurons: an in-vivo electrophysiological study in rats with monoaminergic lesions.

Guiard BP, El Mansari M, Merali Z, Blier P.

Int J Neuropsychopharmacol. 2008 Aug;11(5):625-39. doi: 10.1017/S1461145707008383. Epub 2008 Jan 21.

PMID:
18205979
40.

Consequences of changes in BDNF levels on serotonin neurotransmission, 5-HT transporter expression and function: studies in adult mice hippocampus.

Deltheil T, Guiard BP, Guilloux JP, Nicolas L, Deloménie C, Repérant C, Le Maitre E, Leroux-Nicollet I, Benmansour S, Coudoré F, David DJ, Gardier AM.

Pharmacol Biochem Behav. 2008 Aug;90(2):174-83. Epub 2007 Oct 3. Review.

PMID:
17980409
41.

Substance P neurokinin 1 receptor activation within the dorsal raphe nucleus controls serotonin release in the mouse frontal cortex.

Guiard BP, Guilloux JP, Reperant C, Hunt SP, Toth M, Gardier AM.

Mol Pharmacol. 2007 Dec;72(6):1411-8. Epub 2007 Sep 21.

PMID:
17890358
42.

Brain-derived neurotrophic factor-deficient mice exhibit a hippocampal hyperserotonergic phenotype.

Guiard BP, David DJ, Deltheil T, Chenu F, Le Maître E, Renoir T, Leroux-Nicollet I, Sokoloff P, Lanfumey L, Hamon M, Andrews AM, Hen R, Gardier AM.

Int J Neuropsychopharmacol. 2008 Feb;11(1):79-92. Epub 2007 Jun 11.

PMID:
17559709
43.

Antidepressant-like activity of selective serotonin reuptake inhibitors combined with a NK1 receptor antagonist in the mouse forced swimming test.

Chenu F, Guiard BP, Bourin M, Gardier AM.

Behav Brain Res. 2006 Sep 25;172(2):256-63. Epub 2006 Jun 27.

PMID:
16806519
45.

Blockade of 5-HT1A receptors by (+/-)-pindolol potentiates cortical 5-HT outflow, but not antidepressant-like activity of paroxetine: microdialysis and behavioral approaches in 5-HT1A receptor knockout mice.

Guilloux JP, David DJ, Guiard BP, Chenu F, Repérant C, Toth M, Bourin M, Gardier AM.

Neuropsychopharmacology. 2006 Oct;31(10):2162-72. Epub 2006 Jan 25.

46.

Sustained pharmacological blockade of NK1 substance P receptors causes functional desensitization of dorsal raphe 5-HT 1A autoreceptors in mice.

Guiard BP, Froger N, Hamon M, Gardier AM, Lanfumey L.

J Neurochem. 2005 Dec;95(6):1713-23. Epub 2005 Oct 7.

47.

Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors.

Maskos U, Molles BE, Pons S, Besson M, Guiard BP, Guilloux JP, Evrard A, Cazala P, Cormier A, Mameli-Engvall M, Dufour N, Cloëz-Tayarani I, Bemelmans AP, Mallet J, Gardier AM, David V, Faure P, Granon S, Changeux JP.

Nature. 2005 Jul 7;436(7047):103-7.

PMID:
16001069
48.

Rapid and precise method to locate microdialysis probe implantation in the rodent brain.

Bert L, Favale D, Jego G, Greve P, Guilloux JP, Guiard BP, Gardier AM, Suaud-Chagny MF, Lestage P.

J Neurosci Methods. 2004 Dec 30;140(1-2):53-7.

PMID:
15589334
49.

Blockade of substance P (neurokinin 1) receptors enhances extracellular serotonin when combined with a selective serotonin reuptake inhibitor: an in vivo microdialysis study in mice.

Guiard BP, Przybylski C, Guilloux JP, Seif I, Froger N, De Felipe C, Hunt SP, Lanfumey L, Gardier AM.

J Neurochem. 2004 Apr;89(1):54-63.

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