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Items: 21

1.

Probenecid-Boosted Tenofovir: A PBPK model informed strategy for on-demand HIV pre-exposure prophylaxis.

Liu SN, Desta Z, Gufford BT.

CPT Pharmacometrics Syst Pharmacol. 2019 Nov 20. doi: 10.1002/psp4.12481. [Epub ahead of print]

2.

Inhibitory Effects of Probenecid on Pharmacokinetics of Tenofovir Disoproxil Fumarate and Emtricitabine for On-Demand HIV Pre-Exposure Prophylaxis.

Liu SN, Gufford BT, Lu JBL, Bushman LR, Anderson PL, Bergstrom RF, Desta Z, Gupta SK.

Clin Pharmacol Ther. 2019 Nov 1. doi: 10.1002/cpt.1714. [Epub ahead of print]

PMID:
31675437
3.

Developing User Personas to Aid in the Design of a User-Centered Natural Product-Drug Interaction Information Resource for Researchers.

Boyce RD, Ragueneau-Majlessi I, Yu J, Tay-Sontheimer J, Kinsella C, Chou E, Brochhausen M, Judkins J, Gufford BT, Pinkleton BE, Cooney R, Paine MF, McCune JS.

AMIA Annu Symp Proc. 2018 Dec 5;2018:279-287. eCollection 2018.

4.

Mechanistic Assessment of Extrahepatic Contributions to Glucuronidation of Integrase Strand Transfer Inhibitors.

Liu SN, Lu JBL, Watson CJW, Lazarus P, Desta Z, Gufford BT.

Drug Metab Dispos. 2019 May;47(5):535-544. doi: 10.1124/dmd.118.085035. Epub 2019 Feb 25.

PMID:
30804050
5.

Drug-gene and drug-drug interactions associated with tramadol and codeine therapy in the INGENIOUS trial.

Fulton CR, Zang Y, Desta Z, Rosenman MB, Holmes AM, Decker BS, Zhang Y, T Callaghan J, Pratt VM, Levy KD, Gufford BT, Dexter PR, Skaar TC, Eadon MT.

Pharmacogenomics. 2019 Apr;20(6):397-408. doi: 10.2217/pgs-2018-0205. Epub 2019 Feb 20.

PMID:
30784356
6.

Pharmacogenetics and Practice: Tailoring Prescribing for Safety and Effectiveness.

Fulton CR, Swart M, De Luca T, Liu SN, Collins KS, Desta Z, Gufford BT, Eadon MT.

J Nurse Pract. 2018 Nov-Dec;14(10):697-704.e1. doi: 10.1016/j.nurpra.2018.09.021. Epub 2018 Nov 2. No abstract available.

7.

Rifampin modulation of xeno- and endobiotic conjugating enzyme mRNA expression and associated microRNAs in human hepatocytes.

Gufford BT, Robarge JD, Eadon MT, Gao H, Lin H, Liu Y, Desta Z, Skaar TC.

Pharmacol Res Perspect. 2018 Mar 26;6(2):e00386. doi: 10.1002/prp2.386. eCollection 2018 Apr.

8.

Variants in the CYP2B6 3'UTR Alter In Vitro and In Vivo CYP2B6 Activity: Potential Role of MicroRNAs.

Burgess KS, Ipe J, Swart M, Metzger IF, Lu J, Gufford BT, Thong N, Desta Z, Gaedigk R, Pearce RE, Gaedigk A, Liu Y, Skaar TC.

Clin Pharmacol Ther. 2018 Jul;104(1):130-138. doi: 10.1002/cpt.892. Epub 2017 Oct 25.

9.

Clinical and educational impact of pharmacogenomics testing: a case series from the INGENIOUS trial.

Pierson RC, Gufford BT, Desta Z, Eadon MT.

Pharmacogenomics. 2017 Jun;18(9):835-841. doi: 10.2217/pgs-2017-0042. Epub 2017 Jun 8.

10.

Comparison of a New Intranasal Naloxone Formulation to Intramuscular Naloxone: Results from Hypothesis-generating Small Clinical Studies.

Gufford BT, Ainslie GR, White JR Jr, Layton ME, Padowski JM, Pollack GM, Paine MF.

Clin Transl Sci. 2017 Sep;10(5):380-386. doi: 10.1111/cts.12473. Epub 2017 May 23.

11.

Chiral Plasma Pharmacokinetics and Urinary Excretion of Bupropion and Metabolites in Healthy Volunteers.

Masters AR, Gufford BT, Lu JB, Metzger IF, Jones DR, Desta Z.

J Pharmacol Exp Ther. 2016 Aug;358(2):230-8. doi: 10.1124/jpet.116.232876. Epub 2016 Jun 2.

12.

Quantitative prediction and clinical evaluation of an unexplored herb-drug interaction mechanism in healthy volunteers.

Gufford BT, Barr JT, González-Pérez V, Layton ME, White JR Jr, Oberlies NH, Paine MF.

CPT Pharmacometrics Syst Pharmacol. 2015 Dec;4(12):701-10. doi: 10.1002/psp4.12047. Epub 2015 Nov 28.

13.

Implementation of a pharmacogenomics consult service to support the INGENIOUS trial.

Eadon MT, Desta Z, Levy KD, Decker BS, Pierson RC, Pratt VM, Callaghan JT, Rosenman MB, Carpenter JS, Holmes AM, McDonald CA, Benson EA, Patil AS, Vuppalanchi R, Gufford BT, Dave N, Robarge JD, Hyder MA, Haas DM, Kreutz RP, Dexter PR, Skaar TC, Flockhart DA.

Clin Pharmacol Ther. 2016 Jul;100(1):63-6. doi: 10.1002/cpt.347. Epub 2016 Mar 31. Review.

14.

Stereoselective Glucuronidation of Bupropion Metabolites In Vitro and In Vivo.

Gufford BT, Lu JB, Metzger IF, Jones DR, Desta Z.

Drug Metab Dispos. 2016 Apr;44(4):544-53. doi: 10.1124/dmd.115.068908. Epub 2016 Jan 22. Erratum in: Drug Metab Dispos. 2016 Nov;44(11):1852.

15.

Chemoenzymatic Synthesis, Characterization, and Scale-Up of Milk Thistle Flavonolignan Glucuronides.

Gufford BT, Graf TN, Paguigan ND, Oberlies NH, Paine MF.

Drug Metab Dispos. 2015 Nov;43(11):1734-43. doi: 10.1124/dmd.115.066076. Epub 2015 Aug 27.

16.

Milk Thistle Constituents Inhibit Raloxifene Intestinal Glucuronidation: A Potential Clinically Relevant Natural Product-Drug Interaction.

Gufford BT, Chen G, Vergara AG, Lazarus P, Oberlies NH, Paine MF.

Drug Metab Dispos. 2015 Sep;43(9):1353-9. doi: 10.1124/dmd.115.065086. Epub 2015 Jun 12.

17.

Identification of diet-derived constituents as potent inhibitors of intestinal glucuronidation.

Gufford BT, Chen G, Lazarus P, Graf TN, Oberlies NH, Paine MF.

Drug Metab Dispos. 2014 Oct;42(10):1675-83. doi: 10.1124/dmd.114.059451. Epub 2014 Jul 9.

18.

Physiologically based pharmacokinetic modeling framework for quantitative prediction of an herb-drug interaction.

Brantley SJ, Gufford BT, Dua R, Fediuk DJ, Graf TN, Scarlett YV, Frederick KS, Fisher MB, Oberlies NH, Paine MF.

CPT Pharmacometrics Syst Pharmacol. 2014 Mar 26;3:e107. doi: 10.1038/psp.2013.69.

19.

pH-dependent stability of creatine ethyl ester: relevance to oral absorption.

Gufford BT, Ezell EL, Robinson DH, Miller DW, Miller NJ, Gu X, Vennerstrom JL.

J Diet Suppl. 2013 Sep;10(3):241-51. doi: 10.3109/19390211.2013.822453.

20.

Semisynthesis, cytotoxicity, antiviral activity, and drug interaction liability of 7-O-methylated analogues of flavonolignans from milk thistle.

Althagafy HS, Graf TN, Sy-Cordero AA, Gufford BT, Paine MF, Wagoner J, Polyak SJ, Croatt MP, Oberlies NH.

Bioorg Med Chem. 2013 Jul 1;21(13):3919-26. doi: 10.1016/j.bmc.2013.04.017. Epub 2013 Apr 16.

21.

Physicochemical characterization of creatine N-methylguanidinium salts.

Gufford BT, Sriraghavan K, Miller NJ, Miller DW, Gu X, Vennerstrom JL, Robinson DH.

J Diet Suppl. 2010 Sep;7(3):240-52. doi: 10.3109/19390211.2010.491507.

PMID:
22432515

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