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Items: 42

1.

Polygenic risk associated with post-traumatic stress disorder onset and severity.

Misganaw B, Guffanti G, Lori A, Abu-Amara D, Flory JD; SBPBC, Mueller S, Yehuda R, Jett M, Marmar CR, Ressler KJ, Doyle FJ 3rd.

Transl Psychiatry. 2019 Jun 7;9(1):165. doi: 10.1038/s41398-019-0497-3.

2.

The Distinctiveness of Grief, Depression, and Posttraumatic Stress: Lessons From Children After 9/11.

Geronazzo-Alman L, Fan B, Duarte CS, Layne CM, Wicks J, Guffanti G, Musa GJ, Hoven CW.

J Am Acad Child Adolesc Psychiatry. 2019 Mar 13. pii: S0890-8567(19)30189-3. doi: 10.1016/j.jaac.2018.12.012. [Epub ahead of print]

PMID:
30877043
3.

Novel Bioinformatics Approach Identifies Transcriptional Profiles of Lineage-Specific Transposable Elements at Distinct Loci in the Human Dorsolateral Prefrontal Cortex.

Guffanti G, Bartlett A, Klengel T, Klengel C, Hunter R, Glinsky G, Macciardi F.

Mol Biol Evol. 2018 Oct 1;35(10):2435-2453. doi: 10.1093/molbev/msy143.

4.

Polygenic risk score, genome-wide association, and gene set analyses of cognitive domain deficits in schizophrenia.

Nakahara S, Medland S, Turner JA, Calhoun VD, Lim KO, Mueller BA, Bustillo JR, O'Leary DS, Vaidya JG, McEwen S, Voyvodic J, Belger A, Mathalon DH, Ford JM, Guffanti G, Macciardi F, Potkin SG, van Erp TGM.

Schizophr Res. 2018 Nov;201:393-399. doi: 10.1016/j.schres.2018.05.041. Epub 2018 Jun 12.

PMID:
29907492
5.

Noncoding RNAs: Stress, Glucocorticoids, and Posttraumatic Stress Disorder.

Daskalakis NP, Provost AC, Hunter RG, Guffanti G.

Biol Psychiatry. 2018 May 15;83(10):849-865. doi: 10.1016/j.biopsych.2018.01.009. Epub 2018 Jan 31. Review.

6.

Comorbidity classes and associated impairment, demographics and 9/11-exposures in 8,236 children and adolescents.

Geronazzo-Alman L, Guffanti G, Eisenberg R, Fan B, Musa GJ, Wicks J, Bresnahan M, Duarte CS, Hoven C.

J Psychiatr Res. 2018 Jan;96:171-177. doi: 10.1016/j.jpsychires.2017.10.012. Epub 2017 Oct 16.

PMID:
29078153
7.

Serine Racemase and D-serine in the Amygdala Are Dynamically Involved in Fear Learning.

Balu DT, Presti KT, Huang CCY, Muszynski K, Radzishevsky I, Wolosker H, Guffanti G, Ressler KJ, Coyle JT.

Biol Psychiatry. 2018 Feb 1;83(3):273-283. doi: 10.1016/j.biopsych.2017.08.012. Epub 2017 Aug 26.

8.

FKBP5 DNA methylation does not mediate the association between childhood maltreatment and depression symptom severity in the Detroit Neighborhood Health Study.

Bustamante AC, Aiello AE, Guffanti G, Galea S, Wildman DE, Uddin M.

J Psychiatr Res. 2018 Jan;96:39-48. doi: 10.1016/j.jpsychires.2017.09.016. Epub 2017 Sep 18.

9.

Epigenome-wide association of PTSD from heterogeneous cohorts with a common multi-site analysis pipeline.

Ratanatharathorn A, Boks MP, Maihofer AX, Aiello AE, Amstadter AB, Ashley-Koch AE, Baker DG, Beckham JC, Bromet E, Dennis M, Garrett ME, Geuze E, Guffanti G, Hauser MA, Kilaru V, Kimbrel NA, Koenen KC, Kuan PF, Logue MW, Luft BJ, Miller MW, Mitchell C, Nugent NR, Ressler KJ, Rutten BPF, Stein MB, Vermetten E, Vinkers CH, Youssef NA; VA Mid-Atlantic MIRECC Workgroup; PGC PTSD Epigenetics Workgroup, Uddin M, Nievergelt CM, Smith AK.

Am J Med Genet B Neuropsychiatr Genet. 2017 Sep;174(6):619-630. doi: 10.1002/ajmg.b.32568. Epub 2017 Jul 10.

10.

An epigenome-wide DNA methylation study of PTSD and depression in World Trade Center responders.

Kuan PF, Waszczuk MA, Kotov R, Marsit CJ, Guffanti G, Gonzalez A, Yang X, Koenen K, Bromet E, Luft BJ.

Transl Psychiatry. 2017 Jun 27;7(6):e1158. doi: 10.1038/tp.2017.130.

11.

Effects of Serotonin Transporter Gene Variation on Impulsivity Mediated by Default Mode Network: A Family Study of Depression.

Cha J, Guffanti G, Gingrich J, Talati A, Wickramaratne P, Weissman M, Posner J.

Cereb Cortex. 2018 Jun 1;28(6):1911-1921. doi: 10.1093/cercor/bhx097.

12.

Largest GWAS of PTSD (N=20‚ÄČ070) yields genetic overlap with schizophrenia and sex differences in heritability.

Duncan LE, Ratanatharathorn A, Aiello AE, Almli LM, Amstadter AB, Ashley-Koch AE, Baker DG, Beckham JC, Bierut LJ, Bisson J, Bradley B, Chen CY, Dalvie S, Farrer LA, Galea S, Garrett ME, Gelernter JE, Guffanti G, Hauser MA, Johnson EO, Kessler RC, Kimbrel NA, King A, Koen N, Kranzler HR, Logue MW, Maihofer AX, Martin AR, Miller MW, Morey RA, Nugent NR, Rice JP, Ripke S, Roberts AL, Saccone NL, Smoller JW, Stein DJ, Stein MB, Sumner JA, Uddin M, Ursano RJ, Wildman DE, Yehuda R, Zhao H, Daly MJ, Liberzon I, Ressler KJ, Nievergelt CM, Koenen KC.

Mol Psychiatry. 2018 Mar;23(3):666-673. doi: 10.1038/mp.2017.77. Epub 2017 Apr 25.

13.

Cumulative exposure to work-related traumatic events and current post-traumatic stress disorder in New York City's first responders.

Geronazzo-Alman L, Eisenberg R, Shen S, Duarte CS, Musa GJ, Wicks J, Fan B, Doan T, Guffanti G, Bresnahan M, Hoven CW.

Compr Psychiatry. 2017 Apr;74:134-143. doi: 10.1016/j.comppsych.2016.12.003. Epub 2016 Dec 21.

14.

Homogeneity of Severe Posttraumatic Stress Disorder Symptom Profiles in Children and Adolescents Across Gender, Age, and Traumatic Experiences Related to 9/11.

Guffanti G, Geronazzo-Alman L, Fan B, Duarte CS, Musa GJ, Hoven CW.

J Trauma Stress. 2016 Oct;29(5):430-439. doi: 10.1002/jts.22134.

PMID:
27727511
15.

Heritability of major depressive and comorbid anxiety disorders in multi-generational families at high risk for depression.

Guffanti G, Gameroff MJ, Warner V, Talati A, Glatt CE, Wickramaratne P, Weissman MM.

Am J Med Genet B Neuropsychiatr Genet. 2016 Dec;171(8):1072-1079. doi: 10.1002/ajmg.b.32477. Epub 2016 Jul 25.

PMID:
27452917
16.

Multivariate Methods for Genetic Variants Selection and Risk Prediction in Cardiovascular Diseases.

Malovini A, Bellazzi R, Napolitano C, Guffanti G.

Front Cardiovasc Med. 2016 Jun 8;3:17. doi: 10.3389/fcvm.2016.00017. eCollection 2016. Review.

17.

Epigenetic mechanisms and associated brain circuits in the regulation of positive emotions: A role for transposable elements.

Gaudi S, Guffanti G, Fallon J, Macciardi F.

J Comp Neurol. 2016 Oct 15;524(15):2944-54. doi: 10.1002/cne.24046. Epub 2016 Jul 24. Review.

18.

LINE1 insertions as a genomic risk factor for schizophrenia: Preliminary evidence from an affected family.

Guffanti G, Gaudi S, Klengel T, Fallon JH, Mangalam H, Madduri R, Rodriguez A, DeCrescenzo P, Glovienka E, Sobell J, Klengel C, Pato M, Ressler KJ, Pato C, Macciardi F.

Am J Med Genet B Neuropsychiatr Genet. 2016 Jun;171(4):534-45. doi: 10.1002/ajmg.b.32437. Epub 2016 Mar 16.

PMID:
26990047
19.

Insulin receptor variants and obesity-related cancers in the Framingham Heart Study.

Parekh N, Guffanti G, Lin Y, Ochs-Balcom HM, Makarem N, Hayes R.

Cancer Causes Control. 2015 Aug;26(8):1189-95. doi: 10.1007/s10552-015-0613-5. Epub 2015 Jun 16.

PMID:
26077721
20.

Genetic variants within the serotonin transporter associated with familial risk for major depression.

Talati A, Guffanti G, Odgerel Z, Ionita-Laza I, Malm H, Sourander A, Brown AS, Wickramaratne PJ, Gingrich JA, Weissman MM.

Psychiatry Res. 2015 Jul 30;228(1):170-3. doi: 10.1016/j.psychres.2015.04.015. Epub 2015 Apr 18.

21.

Association of the rs2242446 polymorphism in the norepinephrine transporter gene SLC6A2 and anxious arousal symptoms of posttraumatic stress disorder.

Pietrzak RH, Sumner JA, Aiello AE, Uddin M, Neumeister A, Guffanti G, Koenen KC.

J Clin Psychiatry. 2015 Apr;76(4):e537-8. doi: 10.4088/JCP.14l09346. No abstract available.

22.

An analysis of gene expression in PTSD implicates genes involved in the glucocorticoid receptor pathway and neural responses to stress.

Logue MW, Smith AK, Baldwin C, Wolf EJ, Guffanti G, Ratanatharathorn A, Stone A, Schichman SA, Humphries D, Binder EB, Arloth J, Menke A, Uddin M, Wildman D, Galea S, Aiello AE, Koenen KC, Miller MW.

Psychoneuroendocrinology. 2015 Jul;57:1-13. doi: 10.1016/j.psyneuen.2015.03.016. Epub 2015 Mar 24.

23.

No association between RORA polymorphisms and PTSD in two independent samples.

Guffanti G, Ashley-Koch AE, Roberts AL, Garrett ME, Solovieff N, Ratanatharathorn A, De Vivo I, Dennis M, Ranu H, Smoller JW, Liu Y, Purcell SM; Veterans Affairs Mid-Atlantic Mental Illness Research, Education, and Clinical Center Workgroup, Beckham J, Hauser MA, Koenen KC.

Mol Psychiatry. 2014 Oct;19(10):1056-7. doi: 10.1038/mp.2014.19. Epub 2014 Jul 22. No abstract available.

PMID:
25048002
24.

Transposable elements and psychiatric disorders.

Guffanti G, Gaudi S, Fallon JH, Sobell J, Potkin SG, Pato C, Macciardi F.

Am J Med Genet B Neuropsychiatr Genet. 2014 Apr;165B(3):201-16. doi: 10.1002/ajmg.b.32225. Epub 2014 Feb 28. Review.

PMID:
24585726
25.

A newly identified group of adolescents at "invisible" risk for psychopathology and suicidal behavior: findings from the SEYLE study.

Carli V, Hoven CW, Wasserman C, Chiesa F, Guffanti G, Sarchiapone M, Apter A, Balazs J, Brunner R, Corcoran P, Cosman D, Haring C, Iosue M, Kaess M, Kahn JP, Keeley H, Postuvan V, Saiz P, Varnik A, Wasserman D.

World Psychiatry. 2014 Feb;13(1):78-86. doi: 10.1002/wps.20088.

26.

Genome-wide association study implicates a novel RNA gene, the lincRNA AC068718.1, as a risk factor for post-traumatic stress disorder in women.

Guffanti G, Galea S, Yan L, Roberts AL, Solovieff N, Aiello AE, Smoller JW, De Vivo I, Ranu H, Uddin M, Wildman DE, Purcell S, Koenen KC.

Psychoneuroendocrinology. 2013 Dec;38(12):3029-38. doi: 10.1016/j.psyneuen.2013.08.014. Epub 2013 Sep 8.

27.

Increased CNV-region deletions in mild cognitive impairment (MCI) and Alzheimer's disease (AD) subjects in the ADNI sample.

Guffanti G, Torri F, Rasmussen J, Clark AP, Lakatos A, Turner JA, Fallon JH, Saykin AJ, Weiner M; ADNI the Alzheimer's Disease Neuroimaging Initiative, Vawter MP, Knowles JA, Potkin SG, Macciardi F.

Genomics. 2013 Aug;102(2):112-22. doi: 10.1016/j.ygeno.2013.04.004. Epub 2013 Apr 11.

28.

Considering trauma exposure in the context of genetics studies of posttraumatic stress disorder: a systematic review.

Digangi J, Guffanti G, McLaughlin KA, Koenen KC.

Biol Mood Anxiety Disord. 2013 Jan 3;3(1):2. doi: 10.1186/2045-5380-3-2.

29.

A genome-wide association study of post-traumatic stress disorder identifies the retinoid-related orphan receptor alpha (RORA) gene as a significant risk locus.

Logue MW, Baldwin C, Guffanti G, Melista E, Wolf EJ, Reardon AF, Uddin M, Wildman D, Galea S, Koenen KC, Miller MW.

Mol Psychiatry. 2013 Aug;18(8):937-42. doi: 10.1038/mp.2012.113. Epub 2012 Aug 7.

30.

SNP-based pathway enrichment analysis for genome-wide association studies.

Weng L, Macciardi F, Subramanian A, Guffanti G, Potkin SG, Yu Z, Xie X.

BMC Bioinformatics. 2011 Apr 15;12:99. doi: 10.1186/1471-2105-12-99.

31.

Role of UBE3A and ATP10A genes in autism susceptibility region 15q11-q13 in an Italian population: a positive replication for UBE3A.

Guffanti G, Strik Lievers L, Bonati MT, Marchi M, Geronazzo L, Nardocci N, Estienne M, Larizza L, Macciardi F, Russo S.

Psychiatry Res. 2011 Jan 30;185(1-2):33-8. doi: 10.1016/j.psychres.2010.04.057. Epub 2010 Jul 6.

PMID:
20609483
32.

Identifying gene regulatory networks in schizophrenia.

Potkin SG, Macciardi F, Guffanti G, Fallon JH, Wang Q, Turner JA, Lakatos A, Miles MF, Lander A, Vawter MP, Xie X.

Neuroimage. 2010 Nov 15;53(3):839-47. doi: 10.1016/j.neuroimage.2010.06.036. Epub 2010 Jun 22. Review.

33.

Association between mitochondrial DNA variations and Alzheimer's disease in the ADNI cohort.

Lakatos A, Derbeneva O, Younes D, Keator D, Bakken T, Lvova M, Brandon M, Guffanti G, Reglodi D, Saykin A, Weiner M, Macciardi F, Schork N, Wallace DC, Potkin SG; Alzheimer's Disease Neuroimaging Initiative.

Neurobiol Aging. 2010 Aug;31(8):1355-63. doi: 10.1016/j.neurobiolaging.2010.04.031. Epub 2010 Jun 11.

34.

Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease.

Potkin SG, Guffanti G, Lakatos A, Turner JA, Kruggel F, Fallon JH, Saykin AJ, Orro A, Lupoli S, Salvi E, Weiner M, Macciardi F; Alzheimer's Disease Neuroimaging Initiative.

PLoS One. 2009 Aug 7;4(8):e6501. doi: 10.1371/journal.pone.0006501.

35.

Genome-wide strategies for discovering genetic influences on cognition and cognitive disorders: methodological considerations.

Potkin SG, Turner JA, Guffanti G, Lakatos A, Torri F, Keator DB, Macciardi F.

Cogn Neuropsychiatry. 2009;14(4-5):391-418. doi: 10.1080/13546800903059829.

36.

Gene discovery through imaging genetics: identification of two novel genes associated with schizophrenia.

Potkin SG, Turner JA, Fallon JA, Lakatos A, Keator DB, Guffanti G, Macciardi F.

Mol Psychiatry. 2009 Apr;14(4):416-28. doi: 10.1038/mp.2008.127. Epub 2008 Dec 9.

37.

A genome-wide association study of schizophrenia using brain activation as a quantitative phenotype.

Potkin SG, Turner JA, Guffanti G, Lakatos A, Fallon JH, Nguyen DD, Mathalon D, Ford J, Lauriello J, Macciardi F; FBIRN.

Schizophr Bull. 2009 Jan;35(1):96-108. doi: 10.1093/schbul/sbn155. Epub 2008 Nov 20.

38.

SNPLims: a data management system for genome wide association studies.

Orro A, Guffanti G, Salvi E, Macciardi F, Milanesi L.

BMC Bioinformatics. 2008 Mar 26;9 Suppl 2:S13. doi: 10.1186/1471-2105-9-S2-S13.

39.

Lack of replication of genetic associations with human longevity.

Novelli V, Viviani Anselmi C, Roncarati R, Guffanti G, Malovini A, Piluso G, Puca AA.

Biogerontology. 2008 Apr;9(2):85-92. Epub 2007 Nov 23.

40.

Common genetic variants and haplotypes in renal CLCNKA gene are associated to salt-sensitive hypertension.

Barlassina C, Dal Fiume C, Lanzani C, Manunta P, Guffanti G, Ruello A, Bianchi G, Del Vecchio L, Macciardi F, Cusi D.

Hum Mol Genet. 2007 Jul 1;16(13):1630-8. Epub 2007 May 17.

PMID:
17510212
42.

[Surgical treatment of pheochromocytoma: our experience].

Fenaroli P, Sacco R, Guffanti G, Cassinelli GB.

G Chir. 1989 May;10(5):251-7. Italian.

PMID:
2518562

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