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Items: 1 to 50 of 135


Limited evidence of physical therapy on balance after stroke: A systematic review and meta-analysis.

Hugues A, Di Marco J, Ribault S, Ardaillon H, Janiaud P, Xue Y, Zhu J, Pires J, Khademi H, Rubio L, Hernandez Bernal P, Bahar Y, Charvat H, Szulc P, Ciumas C, Won H, Cucherat M, Bonan I, Gueyffier F, Rode G.

PLoS One. 2019 Aug 29;14(8):e0221700. doi: 10.1371/journal.pone.0221700. eCollection 2019.


Comparison of crossover and parallel-group designs for the identification of a binary predictive biomarker of the treatment effect.

Grenet G, Blanc C, Bardel C, Gueyffier F, Roy P.

Basic Clin Pharmacol Toxicol. 2019 Jul 16. doi: 10.1111/bcpt.13293. [Epub ahead of print]


GLUcose COntrol Safety & Efficacy in type 2 DIabetes, a systematic review and NETwork meta-analysis.

Grenet G, Ribault S, Nguyen GB, Glais F, Metge A, Linet T, Kassai-Koupai B, Cornu C, Bejan-Angoulvant T, Erpeldinger S, Boussageon R, Gouraud A, Bonnet F, Cucherat M, Moulin P, Gueyffier F.

PLoS One. 2019 Jun 25;14(6):e0217701. doi: 10.1371/journal.pone.0217701. eCollection 2019.


Inconclusive efficacy of intervention on upper-limb function after tetraplegia: A systematic review and meta-analysis.

Mateo S, Di Marco J, Cucherat M, Gueyffier F, Rode G.

Ann Phys Rehabil Med. 2019 Jun 21. pii: S1877-0657(19)30076-4. doi: 10.1016/ [Epub ahead of print] Review.


Minoxidil versus placebo in the treatment of arterial wall hypertrophy in children with Williams Beuren Syndrome: a randomized controlled trial.

Kassai B, Bouyé P, Gilbert-Dussardier B, Godart F, Thambo JB, Rossi M, Cochat P, Chirossel P, Luong S, Serusclat A, Canterino I, Mercier C, Rabilloud M, Pivot C, Pirot F, Ginhoux T, Coopman S, Grenet G, Gueyffier F, Di-Fillippo S, Bertholet-Thomas A.

BMC Pediatr. 2019 May 28;19(1):170. doi: 10.1186/s12887-019-1544-1.


Prevalence of giant cell arteritis relapse in patients treated with glucocorticoids: a meta-analysis.

Mainbourg S, Addario A, Samson M, Puéchal X, François M, Durupt S, Gueyffier F, Cucherat M, Durieu I, Reynaud Q, Lega JC.

Arthritis Care Res (Hoboken). 2019 Apr 5. doi: 10.1002/acr.23901. [Epub ahead of print]


Do patients with cystic fibrosis participating in clinical trials demonstrate placebo response? A meta-analysis.

Coton J, Le HH, Veuillet V, Janiaud P, Cucherat M, Kassai-Koupai B, Gueyffier F, Reix P.

J Cyst Fibros. 2019 Jul;18(4):461-467. doi: 10.1016/j.jcf.2019.02.003. Epub 2019 Feb 13.


The contribution of genomics in the medicine of tomorrow, clinical applications and issues.

Laviolle B, Denèfle P, Gueyffier F; participants of Giens XXXIV Round Table “Translational research”.

Therapie. 2019 Feb;74(1):9-15. doi: 10.1016/j.therap.2018.11.012. Epub 2018 Dec 21.


Apport de la génomique dans la médecine de demain, applications cliniques et enjeux.

Laviolle B, Perche O, Gueyffier F; les participants à la table ronde « Recherche translationnelle » des Ateliers de Giens XXXIV.

Therapie. 2019 Feb;74(1):1-8. doi: 10.1016/j.therap.2018.11.011. Epub 2018 Dec 16. French. No abstract available.


The limitations of observation studies for decision making regarding drugs efficacy and safety.

Gueyffier F, Cucherat M.

Therapie. 2019 Apr;74(2):181-185. doi: 10.1016/j.therap.2018.11.001. Epub 2018 Nov 8.


INN or brand name drug prescriptions: a multilevel, cross-sectional study in general practice.

De Bruyne F, Ponçon A, Giai J, Dode X, Darmon D, Colin C, Gueyffier F, Letrilliart L.

Eur J Clin Pharmacol. 2019 Feb;75(2):275-283. doi: 10.1007/s00228-018-2580-8. Epub 2018 Oct 27.


Investigation of one-stage meta-analysis methods for joint longitudinal and time-to-event data through simulation and real data application.

Sudell M, Kolamunnage-Dona R, Gueyffier F, Tudur Smith C.

Stat Med. 2019 Jan 30;38(2):247-268. doi: 10.1002/sim.7961. Epub 2018 Sep 12.


Effectiveness of drug interventions to prevent sudden cardiac death in patients with heart failure and reduced ejection fraction: an overview of systematic reviews.

Al-Gobari M, Al-Aqeel S, Gueyffier F, Burnand B.

BMJ Open. 2018 Jul 28;8(7):e021108. doi: 10.1136/bmjopen-2017-021108. Review.


Sex gap in aging and longevity: can sex chromosomes play a role?

Marais GAB, Gaillard JM, Vieira C, Plotton I, Sanlaville D, Gueyffier F, Lemaitre JF.

Biol Sex Differ. 2018 Jul 17;9(1):33. doi: 10.1186/s13293-018-0181-y. Review.


Combined effect of renal function and serum potassium level in sudden cardiac death in aging hypertensive subjects.

Fauvel JP, Gueyffier F, Thijs L, Ducher M.

Hypertens Res. 2018 Jun;41(6):469-474. doi: 10.1038/s41440-018-0035-3. Epub 2018 Apr 9.


Type 2 diabetes.

Boussageon R, Roustit M, Gueyffier F, Tudrej BV, Rehman MB.

Lancet. 2018 Mar 31;391(10127):1261. doi: 10.1016/S0140-6736(18)30702-5. No abstract available.


Investigation of 2-stage meta-analysis methods for joint longitudinal and time-to-event data through simulation and real data application.

Sudell M, Tudur Smith C, Gueyffier F, Kolamunnage-Dona R.

Stat Med. 2018 Apr 15;37(8):1227-1244. doi: 10.1002/sim.7585. Epub 2017 Dec 18.


Hierarchical evaluation of electrical stimulation protocols for chronic wound healing: An effect size meta-analysis.

Khouri C, Kotzki S, Roustit M, Blaise S, Gueyffier F, Cracowski JL.

Wound Repair Regen. 2017 Sep;25(5):883-891. doi: 10.1111/wrr.12594. Epub 2017 Dec 8. Review.


Individualizing treatment choices in the systolic blood pressure intervention trial.

Ferreira JP, Gregson J, Duarte K, Gueyffier F, Rossignol P, Zannad F, Pocock S.

J Hypertens. 2018 Feb;36(2):428-435. doi: 10.1097/HJH.0000000000001535.


Pharmacotherapy for hypertension in adults aged 18 to 59 years.

Musini VM, Gueyffier F, Puil L, Salzwedel DM, Wright JM.

Cochrane Database Syst Rev. 2017 Aug 16;8:CD008276. doi: 10.1002/14651858.CD008276.pub2. Review.


A sudden death risk score specifically for hypertension: based on 25 648 individual patient data from six randomized controlled trials.

Le HH, Subtil F, Cerou M, Marchant I, Al-Gobari M, Fall M, Mimouni Y, Kassaï B, Lindholm L, Thijs L, Gueyffier F.

J Hypertens. 2017 Nov;35(11):2178-2184. doi: 10.1097/HJH.0000000000001451. Review.


[Acute analgesic effect of paracetamol in primary care: Incomplete evidence].

Gougain M, Moreau A, Boussageon R, Pickering G, Gueyffier F.

Therapie. 2017 Oct;72(5):609-613. doi: 10.1016/j.therap.2017.02.004. Epub 2017 Apr 4. Review. French.


Causes and consequences of variation in offspring body mass: meta-analyses in birds and mammals.

Ronget V, Gaillard JM, Coulson T, Garratt M, Gueyffier F, Lega JC, Lemaître JF.

Biol Rev Camb Philos Soc. 2018 Feb;93(1):1-27. doi: 10.1111/brv.12329. Epub 2017 Apr 9. Review.


No benefits of statins for sudden cardiac death prevention in patients with heart failure and reduced ejection fraction: A meta-analysis of randomized controlled trials.

Al-Gobari M, Le HH, Fall M, Gueyffier F, Burnand B.

PLoS One. 2017 Feb 6;12(2):e0171168. doi: 10.1371/journal.pone.0171168. eCollection 2017.


Comment mesure-t-on le bénéfice net d’un traitement ?

Gueyffier F, Piedbois P, Bergmann JF; les participants à la table ronde n(o) 2 de Giens XXXII.

Therapie. 2017 Feb;72(1):39-49. doi: 10.1016/j.therap.2016.11.057. Epub 2017 Jan 3. French. No abstract available.


How to measure the net benefit of treatment?

Gueyffier F, Piedbois P, Bergmann JF; participants of Giens XXXII Round Table No. 2.

Therapie. 2017 Feb;72(1):51-61. doi: 10.1016/j.therap.2016.12.004. Epub 2017 Jan 3.


Protocol of GLUcose COntrol Safety and Efficacy in type 2 DIabetes, a NETwork meta-analysis: GLUCOSE DINET protocol-Rational and design.

Grenet G, Lajoinie A, Ribault S, Nguyen GB, Linet T, Metge A, Cornu C, Cucherat M, Moulin P, Gueyffier F.

Fundam Clin Pharmacol. 2017 Jun;31(3):258-264. doi: 10.1111/fcp.12263. Epub 2017 Mar 23. Review.


[ECRIN standard requirements for good clinical practices-compliant data management in multinational clinical trials].

Cornu C, Donche A, Coffre C, Le Gouge A, Rym B, Vaugier I, Barbot F, Leizorovicz A, Juge N, Giraud C, Gueyffier F, Félin A, Mura T, Chevassus H, Binquet C; Comité de pilotage du groupe de travail harmonisation des procédures de réseau des CIC.

Therapie. 2016 Oct 13. pii: S0040-5957(16)31137-4. doi: 10.2515/therapie/2015042. [Epub ahead of print] French.


One-step partial or complete caries removal and bonding with antibacterial or traditional self-etch adhesives: study protocol for a randomized controlled trial.

Villat C, Attal JP, Brulat N, Decup F, Doméjean S, Dursun E, Fron-Chabouis H, Jacquot B, Muller Bolla M, Plasse-Pradelle N, Roche L, Maucort-Boulch D, Nony P, Gritsch K, Millet P, Gueyffier F, Grosgogeat B.

Trials. 2016 Aug 15;17:404. doi: 10.1186/s13063-016-1484-0.


Efficacy and safety of insulin in type 2 diabetes: meta-analysis of randomised controlled trials.

Erpeldinger S, Rehman MB, Berkhout C, Pigache C, Zerbib Y, Regnault F, Guérin E, Supper I, Cornu C, Kassaï B, Gueyffier F, Boussageon R.

BMC Endocr Disord. 2016 Jul 8;16(1):39. doi: 10.1186/s12902-016-0120-z.


Antihypertensive pharmacotherapy for prevention of sudden cardiac death in hypertensive individuals.

Taverny G, Mimouni Y, LeDigarcher A, Chevalier P, Thijs L, Wright JM, Gueyffier F.

Cochrane Database Syst Rev. 2016 Mar 10;3:CD011745. doi: 10.1002/14651858.CD011745.pub2. Review.


Impact of Aldosterone Antagonists on Sudden Cardiac Death Prevention in Heart Failure and Post-Myocardial Infarction Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Le HH, El-Khatib C, Mombled M, Guitarian F, Al-Gobari M, Fall M, Janiaud P, Marchant I, Cucherat M, Bejan-Angoulvant T, Gueyffier F.

PLoS One. 2016 Feb 18;11(2):e0145958. doi: 10.1371/journal.pone.0145958. eCollection 2016. Review.


Metformin as firstline treatment for type 2 diabetes: are we sure?

Boussageon R, Gueyffier F, Cornu C.

BMJ. 2016 Jan 8;352:h6748. doi: 10.1136/bmj.h6748. Erratum in: BMJ. 2016;352:i197.


High Risk versus Proportional Benefit: Modelling Equitable Strategies in Cardiovascular Prevention.

Marchant I, Boissel JP, Nony P, Gueyffier F.

PLoS One. 2015 Nov 3;10(11):e0140793. doi: 10.1371/journal.pone.0140793. eCollection 2015.


Is legacy a myth or a reality? We should know, and we do not.

Gueyffier F, Cucherat M.

J Hypertens. 2015 Nov;33(11):2207-9. doi: 10.1097/HJH.0000000000000728. No abstract available.


Comparative transcriptomic analysis between an artificially induced SIRS in healthy individuals and spontaneous sepsis.

Monteiro Sousa C, Boissel JP, Gueyffier F, Olivera-Botello G.

C R Biol. 2015 Oct;338(10):635-42. doi: 10.1016/j.crvi.2015.05.001. Epub 2015 Aug 11.


[ECRIN Standard Requirements for Good Clinical Practices-compliant Data Management in Multinational Clinical Trials].

Cornu C, Donche A, Coffre C, Le Gouge A, Rym B, Vaugier I, Barbot F, Leizorovicz A, Juge N, Giraud C, Gueyffier F, Félin A, Mura T, Chevassus H, Binquet C; le Comité de Pilotage du groupe de travail Harmonisation des procédures de réseau des CIC.

Therapie. 2015 Aug 3. [Epub ahead of print] French.


Different treatment benefits were estimated by clinical trials performed in adults compared with those performed in children.

Janiaud P, Lajoinie A, Cour-Andlauer F, Cornu C, Cochat P, Cucherat M, Gueyffier F, Kassai B.

J Clin Epidemiol. 2015 Oct;68(10):1221-31. doi: 10.1016/j.jclinepi.2015.06.021. Epub 2015 Jul 9. Review.


Meta-analysis of a continuous outcome combining individual patient data and aggregate data: a method based on simulated individual patient data.

Yamaguchi Y, Sakamoto W, Goto M, Staessen JA, Wang J, Gueyffier F, Riley RD.

Res Synth Methods. 2014 Dec;5(4):322-51. doi: 10.1002/jrsm.1119. Epub 2014 Jun 9.


Uptake of systematic reviews and meta-analyses based on individual participant data in clinical practice guidelines: descriptive study.

Vale CL, Rydzewska LH, Rovers MM, Emberson JR, Gueyffier F, Stewart LA; Cochrane IPD Meta-analysis Methods Group.

BMJ. 2015 Mar 6;350:h1088. doi: 10.1136/bmj.h1088.


Translational research: precision medicine, personalized medicine, targeted therapies: marketing or science?

Marquet P, Longeray PH, Barlesi F; participants of round table N°1 of Giens XXX:, Ameye V, Augé P, Cazeneuve B, Chatelut E, Diaz I, Diviné M, Froguel P, Goni S, Gueyffier F, Hoog-Labouret N, Mourah S, Morin-Surroca M, Perche O, Perin-Dureau F, Pigeon M, Tisseau A, Verstuyft C.

Therapie. 2015 Jan-Feb;70(1):1-19. doi: 10.2515/therapie/2014231. Epub 2015 Feb 16. English, French.


Recherche translationnelle : médecine personnalisée, médecine de précision, thérapies ciblées : marketing ou science ?

Marquet P, Longeray PH, Barlesi F; les participants à la table ronde N°1 de Giens XXX :, Ameye V, Augé P, Cazeneuve B, Chatelut E, Diaz I, Diviné M, Froguel P, Goni S, Gueyffier F, Hoog-Labouret N, Mourah S, Morin-Surroca M, Perche O, Perin-Dureau F, Pigeon M, Tisseau A, Verstuyft C.

Therapie. 2015 Jan-Feb;70(1):1-10. doi: 10.2515/therapie/2014230. French. No abstract available.


Comparison of an effect-model-law-based method versus traditional clinical practice guidelines for optimal treatment decision-making: application to statin treatment in the French population.

Kahoul R, Gueyffier F, Amsallem E, Haugh M, Marchant I, Boissel FH, Boissel JP.

J R Soc Interface. 2014 Nov 6;11(100):20140867. doi: 10.1098/rsif.2014.0867.


The effect of methylphenidate on neurofibromatosis type 1: a randomised, double-blind, placebo-controlled, crossover trial.

Lion-François L, Gueyffier F, Mercier C, Gérard D, Herbillon V, Kemlin I, Rodriguez D, Ginhoux T, Peyric E, Coutinho V, Bréant V, des Portes V, Pinson S, Combemale P, Kassaï B; Réseau NF1 Rhône Alpes Auvergne-France.

Orphanet J Rare Dis. 2014 Sep 10;9:142. doi: 10.1186/s13023-014-0142-4.


Cardiovascular events and bleeding risk associated with intravitreal antivascular endothelial growth factor monoclonal antibodies: systematic review and meta-analysis.

Thulliez M, Angoulvant D, Le Lez ML, Jonville-Bera AP, Pisella PJ, Gueyffier F, Bejan-Angoulvant T.

JAMA Ophthalmol. 2014 Nov;132(11):1317-26. doi: 10.1001/jamaophthalmol.2014.2333. Review.


Guidelines for managing high blood pressure.

Cundiff DK, Gueyffier F, Wright JM.

JAMA. 2014 Jul 16;312(3):294. doi: 10.1001/jama.2014.6596. No abstract available.


Improving risk prediction performance for a better guidelines application.

Marchant I, Bejan-Angoulvant T, Le HH, Gueyffier F.

J Hypertens. 2014 Jun;32(6):1192-3. doi: 10.1097/HJH.0000000000000194. No abstract available.


Impact of the reduction of calcineurin inhibitors on renal function in heart transplant patients: a systematic review and meta-analysis.

Cornu C, Dufays C, Gaillard S, Gueyffier F, Redonnet M, Sebbag L, Roussoulières A, Gleissner CA, Groetzner J, Lehmkuhl HB, Potena L, Gullestad L, Cantarovich M, Boissonnat P.

Br J Clin Pharmacol. 2014 Jul;78(1):24-32. doi: 10.1111/bcp.12289. Review.


Clinically relevant efficacy of insulin therapy in patients with type 2 diabetes.

Boussageon R, Gamble JM, Gueyffier F, Cornu C.

Therapie. 2013 Nov-Dec;68(6):415-7. doi: 10.2515/therapie/2013063. Epub 2013 Nov 11. No abstract available.


Are concomitant treatments confounding factors in randomized controlled trials on intensive blood-glucose control in type 2 diabetes? a systematic review.

Boussageon R, Supper I, Erpeldinger S, Cucherat M, Bejan-Angoulvant T, Kassai B, Cornu C, Gueyffier F.

BMC Med Res Methodol. 2013 Aug 30;13:107. doi: 10.1186/1471-2288-13-107. Review.

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