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Items: 10

1.

Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia.

Picaud S, Leonards K, Lambert JP, Dovey O, Wells C, Fedorov O, Monteiro O, Fujisawa T, Wang CY, Lingard H, Tallant C, Nikbin N, Guetzoyan L, Ingham R, Ley SV, Brennan P, Muller S, Samsonova A, Gingras AC, Schwaller J, Vassiliou G, Knapp S, Filippakopoulos P.

Sci Adv. 2016 Oct 12;2(10):e1600760. eCollection 2016 Oct.

2.

A monolith immobilised iridium Cp* catalyst for hydrogen transfer reactions under flow conditions.

Rojo MV, Guetzoyan L, Baxendale IR.

Org Biomol Chem. 2015 Feb 14;13(6):1768-77. doi: 10.1039/c4ob02376e.

PMID:
25500632
3.

Flow Synthesis and Biological Studies of an Analgesic Adamantane Derivative That Inhibits P2X7-Evoked Glutamate Release.

Battilocchio C, Guetzoyan L, Cervetto C, Di Cesare Mannelli L, Frattaroli D, Baxendale IR, Maura G, Rossi A, Sautebin L, Biava M, Ghelardini C, Marcoli M, Ley SV.

ACS Med Chem Lett. 2013 May 22;4(8):704-9. doi: 10.1021/ml400079h. eCollection 2013 Aug 8.

4.

Synthesis and biological evaluation of acridine derivatives as antimalarial agents.

Yu XM, Ramiandrasoa F, Guetzoyan L, Pradines B, Quintino E, Gadelle D, Forterre P, Cresteil T, Mahy JP, Pethe S.

ChemMedChem. 2012 Apr;7(4):587-605. doi: 10.1002/cmdc.201100554. Epub 2012 Feb 13.

PMID:
22331612
5.

An Exo2 derivative affects ER and Golgi morphology and vacuolar sorting in a tissue-specific manner in arabidopsis.

Sorieul M, Langhans M, Guetzoyan L, Hillmer S, Clarkson G, Lord JM, Roberts LM, Robinson DG, Spooner RA, Frigerio L.

Traffic. 2011 Nov;12(11):1552-62. doi: 10.1111/j.1600-0854.2011.01258.x. Epub 2011 Aug 24.

6.

LG186: An inhibitor of GBF1 function that causes Golgi disassembly in human and canine cells.

Boal F, Guetzoyan L, Sessions RB, Zeghouf M, Spooner RA, Lord JM, Cherfils J, Clarkson GJ, Roberts LM, Stephens DJ.

Traffic. 2010 Dec;11(12):1537-51. doi: 10.1111/j.1600-0854.2010.01122.x. Epub 2010 Oct 15.

7.

Fine tuning Exo2, a small molecule inhibitor of secretion and retrograde trafficking pathways in mammalian cells.

Guetzoyan LJ, Spooner RA, Boal F, Stephens DJ, Lord JM, Roberts LM, Clarkson GJ.

Mol Biosyst. 2010 Oct;6(10):2030-8. doi: 10.1039/c0mb00035c. Epub 2010 Aug 9.

PMID:
20697620
8.

Simple oxidation of pyrimidinylhydrazones to triazolopyrimidines and their inhibition of Shiga toxin trafficking.

Guetzoyan LJ, Spooner RA, Lord JM, Roberts LM, Clarkson GJ.

Eur J Med Chem. 2010 Jan;45(1):275-83. doi: 10.1016/j.ejmech.2009.10.007. Epub 2009 Oct 9.

PMID:
19883956
9.

Antimalarial acridines: synthesis, in vitro activity against P. falciparum and interaction with hematin.

Guetzoyan L, Yu XM, Ramiandrasoa F, Pethe S, Rogier C, Pradines B, Cresteil T, Perrée-Fauvet M, Mahy JP.

Bioorg Med Chem. 2009 Dec 1;17(23):8032-9. doi: 10.1016/j.bmc.2009.10.005. Epub 2009 Oct 9.

PMID:
19879150
10.

In vitro efficiency of new acridyl derivatives against Plasmodium falciparum.

Guetzoyan L, Ramiandrasoa F, Dorizon H, Desprez C, Bridoux A, Rogier C, Pradines B, Perrée-Fauvet M.

Bioorg Med Chem. 2007 May 1;15(9):3278-89. Epub 2007 Feb 16.

PMID:
17339112

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