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Items: 21


An improved auxin-inducible degron system preserves native protein levels and enables rapid and specific protein depletion.

Sathyan KM, McKenna BD, Anderson WD, Duarte FM, Core L, Guertin MJ.

Genes Dev. 2019 Aug 29. doi: 10.1101/gad.328237.119. [Epub ahead of print]


Genetic and epigenetic determinants establish a continuum of Hsf1 occupancy and activity across the yeast genome.

Pincus D, Anandhakumar J, Thiru P, Guertin MJ, Erkine AM, Gross DS.

Mol Biol Cell. 2018 Dec 15;29(26):3168-3182. doi: 10.1091/mbc.E18-06-0353. Epub 2018 Oct 17.


Identification of Drivers of Aneuploidy in Breast Tumors.

Pfister K, Pipka JL, Chiang C, Liu Y, Clark RA, Keller R, Skoglund P, Guertin MJ, Hall IM, Stukenberg PT.

Cell Rep. 2018 May 29;23(9):2758-2769. doi: 10.1016/j.celrep.2018.04.102.


Parallel factor ChIP provides essential internal control for quantitative differential ChIP-seq.

Guertin MJ, Cullen AE, Markowetz F, Holding AN.

Nucleic Acids Res. 2018 Jul 6;46(12):e75. doi: 10.1093/nar/gky252.


BART: a transcription factor prediction tool with query gene sets or epigenomic profiles.

Wang Z, Civelek M, Miller CL, Sheffield NC, Guertin MJ, Zang C.

Bioinformatics. 2018 Aug 15;34(16):2867-2869. doi: 10.1093/bioinformatics/bty194.


Universal correction of enzymatic sequence bias reveals molecular signatures of protein/DNA interactions.

Martins AL, Walavalkar NM, Anderson WD, Zang C, Guertin MJ.

Nucleic Acids Res. 2018 Jan 25;46(2):e9. doi: 10.1093/nar/gkx1053.


Up For A Challenge (U4C): Stimulating innovation in breast cancer genetic epidemiology.

Mechanic LE, Lindström S, Daily KM, Sieberts SK, Amos CI, Chen HS, Cox NJ, Dathe M, Feuer EJ, Guertin MJ, Hoffman J, Liu Y, Moore JH, Myers CL, Ritchie MD, Schildkraut J, Schumacher F, Witte JS, Wang W, Williams SM; U4C Challenge Participants; U4C Challenge Data Contributors, Gillanders EM.

PLoS Genet. 2017 Sep 28;13(9):e1006945. doi: 10.1371/journal.pgen.1006945. eCollection 2017 Sep. No abstract available.


Identification of breast cancer associated variants that modulate transcription factor binding.

Liu Y, Walavalkar NM, Dozmorov MG, Rich SS, Civelek M, Guertin MJ.

PLoS Genet. 2017 Sep 28;13(9):e1006761. doi: 10.1371/journal.pgen.1006761. eCollection 2017 Sep.


Transcriptional response to stress is pre-wired by promoter and enhancer architecture.

Vihervaara A, Mahat DB, Guertin MJ, Chu T, Danko CG, Lis JT, Sistonen L.

Nat Commun. 2017 Aug 15;8(1):255. doi: 10.1038/s41467-017-00151-0.


Genome-Wide Identification of Basic Helix-Loop-Helix and NF-1 Motifs Underlying GR Binding Sites in Male Rat Hippocampus.

Pooley JR, Flynn BP, Grøntved L, Baek S, Guertin MJ, Kershaw YM, Birnie MT, Pellatt A, Rivers CA, Schiltz RL, Hager GL, Lightman SL, Conway-Campbell BL.

Endocrinology. 2017 May 1;158(5):1486-1501. doi: 10.1210/en.2016-1929.


Transcription factors GAF and HSF act at distinct regulatory steps to modulate stress-induced gene activation.

Duarte FM, Fuda NJ, Mahat DB, Core LJ, Guertin MJ, Lis JT.

Genes Dev. 2016 Aug 1;30(15):1731-46. doi: 10.1101/gad.284430.116. Epub 2016 Aug 4.


GAGA factor maintains nucleosome-free regions and has a role in RNA polymerase II recruitment to promoters.

Fuda NJ, Guertin MJ, Sharma S, Danko CG, Martins AL, Siepel A, Lis JT.

PLoS Genet. 2015 Mar 27;11(3):e1005108. doi: 10.1371/journal.pgen.1005108. eCollection 2015 Mar.


DNase footprint signatures are dictated by factor dynamics and DNA sequence.

Sung MH, Guertin MJ, Baek S, Hager GL.

Mol Cell. 2014 Oct 23;56(2):275-285. doi: 10.1016/j.molcel.2014.08.016. Epub 2014 Sep 18.


Targeted H3R26 deimination specifically facilitates estrogen receptor binding by modifying nucleosome structure.

Guertin MJ, Zhang X, Anguish L, Kim S, Varticovski L, Lis JT, Hager GL, Coonrod SA.

PLoS Genet. 2014 Sep 11;10(9):e1004613. doi: 10.1371/journal.pgen.1004613. eCollection 2014 Sep.


Transient estrogen receptor binding and p300 redistribution support a squelching mechanism for estradiol-repressed genes.

Guertin MJ, Zhang X, Coonrod SA, Hager GL.

Mol Endocrinol. 2014 Sep;28(9):1522-33. doi: 10.1210/me.2014-1130. Epub 2014 Jul 22.


Mechanisms by which transcription factors gain access to target sequence elements in chromatin.

Guertin MJ, Lis JT.

Curr Opin Genet Dev. 2013 Apr;23(2):116-23. doi: 10.1016/j.gde.2012.11.008. Epub 2012 Dec 19. Review.


Peptidylarginine deiminase 2-catalyzed histone H3 arginine 26 citrullination facilitates estrogen receptor α target gene activation.

Zhang X, Bolt M, Guertin MJ, Chen W, Zhang S, Cherrington BD, Slade DJ, Dreyton CJ, Subramanian V, Bicker KL, Thompson PR, Mancini MA, Lis JT, Coonrod SA.

Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):13331-6. doi: 10.1073/pnas.1203280109. Epub 2012 Aug 1.


Accurate prediction of inducible transcription factor binding intensities in vivo.

Guertin MJ, Martins AL, Siepel A, Lis JT.

PLoS Genet. 2012;8(3):e1002610. doi: 10.1371/journal.pgen.1002610. Epub 2012 Mar 29.


Drosophila heat shock system as a general model to investigate transcriptional regulation.

Guertin MJ, Petesch SJ, Zobeck KL, Min IM, Lis JT.

Cold Spring Harb Symp Quant Biol. 2010;75:1-9. doi: 10.1101/sqb.2010.75.039. Epub 2011 Apr 5. Review.


Chromatin landscape dictates HSF binding to target DNA elements.

Guertin MJ, Lis JT.

PLoS Genet. 2010 Sep 9;6(9):e1001114. doi: 10.1371/journal.pgen.1001114.


A molecular analysis of mutations at the complex dumpy locus in Drosophila melanogaster.

Carmon A, Guertin MJ, Grushko O, Marshall B, MacIntyre R.

PLoS One. 2010 Aug 23;5(8):e12319. doi: 10.1371/journal.pone.0012319.

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