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Items: 47

1.

JAK3 Variant, Immune Signatures, DNA Methylation, and Social Determinants Linked to Survival Racial Disparities in Head and Neck Cancer Patients.

Guerrero-Preston R, Lawson F, Rodriguez-Torres S, Noordhuis MG, Pirini F, Manuel L, Valle BL, Hadar T, Rivera B, Folawiyo O, Baez A, Marchionni L, Koch WM, Westra WH, Kim YJ, Eshleman JR, Sidransky D.

Cancer Prev Res (Phila). 2019 Apr;12(4):255-270. doi: 10.1158/1940-6207.CAPR-17-0356. Epub 2019 Feb 18. Erratum in: Cancer Prev Res (Phila). 2019 Jul;12(7):491-492.

PMID:
30777857
2.

PIM1 kinase promotes gallbladder cancer cell proliferation via inhibition of proline-rich Akt substrate of 40 kDa (PRAS40).

Subbannayya T, Leal-Rojas P, Zhavoronkov A, Ozerov IV, Korzinkin M, Babu N, Radhakrishnan A, Chavan S, Raja R, Pinto SM, Patil AH, Barbhuiya MA, Kumar P, Guerrero-Preston R, Navani S, Tiwari PK, Kumar RV, Prasad TSK, Roa JC, Pandey A, Sidransky D, Gowda H, Izumchenko E, Chatterjee A.

J Cell Commun Signal. 2019 Jun;13(2):163-177. doi: 10.1007/s12079-018-00503-5. Epub 2019 Jan 21.

3.

High-resolution microbiome profiling uncovers Fusobacterium nucleatum, Lactobacillus gasseri/johnsonii, and Lactobacillus vaginalis associated to oral and oropharyngeal cancer in saliva from HPV positive and HPV negative patients treated with surgery and chemo-radiation.

Guerrero-Preston R, White JR, Godoy-Vitorino F, Rodríguez-Hilario A, Navarro K, González H, Michailidi C, Jedlicka A, Canapp S, Bondy J, Dziedzic A, Mora-Lagos B, Rivera-Alvarez G, Ili-Gangas C, Brebi-Mieville P, Westra W, Koch W, Kang H, Marchionni L, Kim Y, Sidransky D.

Oncotarget. 2017 Sep 7;8(67):110931-110948. doi: 10.18632/oncotarget.20677. eCollection 2017 Dec 19.

4.

Personalized medicine and Hispanic health: improving health outcomes and reducing health disparities - a National Heart, Lung, and Blood Institute workshop report.

Avilés-Santa ML, Heintzman J, Lindberg NM, Guerrero-Preston R, Ramos K, Abraído-Lanza AL, Bull J, Falcón A, McBurnie MA, Moy E, Papanicolaou G, Piña IL, Popovic J, Suglia SF, Vázquez MA.

BMC Proc. 2017 Oct 3;11(Suppl 11):11. doi: 10.1186/s12919-017-0079-4. eCollection 2017.

5.

INSIG2 rs7566605 single nucleotide variant and global DNA methylation index levels are associated with weight loss in a personalized weight reduction program.

Pirini F, Rodriguez-Torres S, Ayandibu BG, Orera-Clemente M, Gonzalez-de la Vega A, Lawson F, Thorpe RJ Jr, Sidransky D, Guerrero-Preston R.

Mol Med Rep. 2018 Jan;17(1):1699-1709. doi: 10.3892/mmr.2017.8039. Epub 2017 Nov 14.

6.

PAX5 gene as a novel methylation marker that predicts both clinical outcome and cisplatin sensitivity in esophageal squamous cell carcinoma.

Kurimoto K, Hayashi M, Guerrero-Preston R, Koike M, Kanda M, Hirabayashi S, Tanabe H, Takano N, Iwata N, Niwa Y, Takami H, Kobayashi D, Tanaka C, Yamada S, Nakayama G, Sugimoto H, Fujii T, Fujiwara M, Kodera Y.

Epigenetics. 2017;12(10):865-874. doi: 10.1080/15592294.2017.1365207. Epub 2017 Nov 27.

7.

A Panel of Novel Detection and Prognostic Methylated DNA Markers in Primary Non-Small Cell Lung Cancer and Serum DNA.

Ooki A, Maleki Z, Tsay JJ, Goparaju C, Brait M, Turaga N, Nam HS, Rom WN, Pass HI, Sidransky D, Guerrero-Preston R, Hoque MO.

Clin Cancer Res. 2017 Nov 15;23(22):7141-7152. doi: 10.1158/1078-0432.CCR-17-1222. Epub 2017 Aug 29.

8.

Whole Blood Cytokine Response to Local Traffic-Related Particulate Matter in Peruvian Children With and Without Asthma.

Negherbon JP, Romero K, Williams DL, Guerrero-Preston RE, Hartung T, Scott AL, Breysse PN, Checkley W, Hansel NN.

Front Pharmacol. 2017 Mar 30;8:157. doi: 10.3389/fphar.2017.00157. eCollection 2017.

9.

Early detection of gastric cancer using global, genome-wide and IRF4, ELMO1, CLIP4 and MSC DNA methylation in endoscopic biopsies.

Pirini F, Noazin S, Jahuira-Arias MH, Rodriguez-Torres S, Friess L, Michailidi C, Cok J, Combe J, Vargas G, Prado W, Soudry E, Pérez J, Yudin T, Mancinelli A, Unger H, Ili-Gangas C, Brebi-Mieville P, Berg DE, Hayashi M, Sidransky D, Gilman RH, Guerrero-Preston R.

Oncotarget. 2017 Jun 13;8(24):38501-38516. doi: 10.18632/oncotarget.16258.

10.

Prenatal exposure to tobacco smoke leads to increased mitochondrial DNA content in umbilical cord serum associated to reduced gestational age.

Pirini F, Goldman LR, Soudry E, Halden RU, Witter F, Sidransky D, Guerrero-Preston R.

Int J Environ Health Res. 2017 Feb;27(1):52-67. doi: 10.1080/09603123.2016.1268677.

11.

Molecular Triage of Premalignant Lesions in Liquid-Based Cervical Cytology and Circulating Cell-Free DNA from Urine, Using a Panel of Methylated Human Papilloma Virus and Host Genes.

Guerrero-Preston R, Valle BL, Jedlicka A, Turaga N, Folawiyo O, Pirini F, Lawson F, Vergura A, Noordhuis M, Dziedzic A, Pérez G, Renehan M, Guerrero-Diaz C, De Jesus Rodríguez E, Diaz-Montes T, Rodríguez Orengo J, Méndez K, Romaguera J, Trock BJ, Florea L, Sidransky D.

Cancer Prev Res (Phila). 2016 Dec;9(12):915-924. Epub 2016 Sep 26.

12.

16S rRNA amplicon sequencing identifies microbiota associated with oral cancer, human papilloma virus infection and surgical treatment.

Guerrero-Preston R, Godoy-Vitorino F, Jedlicka A, Rodríguez-Hilario A, González H, Bondy J, Lawson F, Folawiyo O, Michailidi C, Dziedzic A, Thangavel R, Hadar T, Noordhuis MG, Westra W, Koch W, Sidransky D.

Oncotarget. 2016 Aug 9;7(32):51320-51334. doi: 10.18632/oncotarget.9710.

13.

Macrophage migration inhibitory factor - a therapeutic target in gallbladder cancer.

Subbannayya T, Leal-Rojas P, Barbhuiya MA, Raja R, Renuse S, Sathe G, Pinto SM, Syed N, Nanjappa V, Patil AH, Garcia P, Sahasrabuddhe NA, Nair B, Guerrero-Preston R, Navani S, Tiwari PK, Santosh V, Sidransky D, Prasad TS, Gowda H, Roa JC, Pandey A, Chatterjee A.

BMC Cancer. 2015 Nov 4;15:843. doi: 10.1186/s12885-015-1855-z.

14.

Chronic exposure to chewing tobacco selects for overexpression of stearoyl-CoA desaturase in normal oral keratinocytes.

Nanjappa V, Renuse S, Sathe GJ, Raja R, Syed N, Radhakrishnan A, Subbannayya T, Patil A, Marimuthu A, Sahasrabuddhe NA, Guerrero-Preston R, Somani BL, Nair B, Kundu GC, Prasad TK, Califano JA, Gowda H, Sidransky D, Pandey A, Chatterjee A.

Cancer Biol Ther. 2015;16(11):1593-603. doi: 10.1080/15384047.2015.1078022. Epub 2015 Sep 21.

15.

Paired box 5 methylation detection by droplet digital PCR for ultra-sensitive deep surgical margins analysis of head and neck squamous cell carcinoma.

Hayashi M, Guerrero-Preston R, Sidransky D, Koch WM.

Cancer Prev Res (Phila). 2015 Nov;8(11):1017-26. doi: 10.1158/1940-6207.CAPR-15-0180. Epub 2015 Aug 24.

16.

Nuclear and mitochondrial DNA alterations in newborns with prenatal exposure to cigarette smoke.

Pirini F, Guida E, Lawson F, Mancinelli A, Guerrero-Preston R.

Int J Environ Res Public Health. 2015 Jan 22;12(2):1135-55. doi: 10.3390/ijerph120201135. Review.

17.

Global and gene-specific DNA methylation pattern discriminates cholecystitis from gallbladder cancer patients in Chile.

Kagohara LT, Schussel JL, Subbannayya T, Sahasrabuddhe N, Lebron C, Brait M, Maldonado L, Valle BL, Pirini F, Jahuira M, Lopez J, Letelier P, Brebi-Mieville P, Ili C, Pandey A, Chatterjee A, Sidransky D, Guerrero-Preston R.

Future Oncol. 2015;11(2):233-49. doi: 10.2217/fon.14.165. Epub 2014 Jul 28.

18.

Cold atmospheric plasma treatment selectively targets head and neck squamous cell carcinoma cells.

Guerrero-Preston R, Ogawa T, Uemura M, Shumulinsky G, Valle BL, Pirini F, Ravi R, Sidransky D, Keidar M, Trink B.

Int J Mol Med. 2014 Oct;34(4):941-6. doi: 10.3892/ijmm.2014.1849. Epub 2014 Jul 11.

19.

Differential promoter methylation of kinesin family member 1a in plasma is associated with breast cancer and DNA repair capacity.

Guerrero-Preston R, Hadar T, Ostrow KL, Soudry E, Echenique M, Ili-Gangas C, Pérez G, Perez J, Brebi-Mieville P, Deschamps J, Morales L, Bayona M, Sidransky D, Matta J.

Oncol Rep. 2014 Aug;32(2):505-12. doi: 10.3892/or.2014.3262. Epub 2014 Jun 13.

20.

Genome-wide and gene-specific epigenomic platforms for hepatocellular carcinoma biomarker development trials.

Michailidi C, Soudry E, Brait M, Maldonado L, Jaffe A, Ili-Gangas C, Brebi-Mieville P, Perez J, Kim MS, Zhong X, Yang Q, Valle B, Meltzer SJ, Torbenson M, Esteller M, Sidransky D, Guerrero-Preston R.

Gastroenterol Res Pract. 2014;2014:597164. doi: 10.1155/2014/597164. Epub 2014 Apr 17.

21.

Key tumor suppressor genes inactivated by "greater promoter" methylation and somatic mutations in head and neck cancer.

Guerrero-Preston R, Michailidi C, Marchionni L, Pickering CR, Frederick MJ, Myers JN, Yegnasubramanian S, Hadar T, Noordhuis MG, Zizkova V, Fertig E, Agrawal N, Westra W, Koch W, Califano J, Velculescu VE, Sidransky D.

Epigenetics. 2014 Jul;9(7):1031-46. doi: 10.4161/epi.29025. Epub 2014 May 1.

22.

Avatars of personalized cancer therapy can lead to a reduction in head and neck cancer survival disparities.

Guerrero-Preston R.

Per Med. 2014 May;11(3):243-246. doi: 10.2217/pme.14.11. No abstract available.

PMID:
29764058
23.

Innovative rapid gene methylation analysis of surgical margin tissues in head and neck cancer.

Hayashi M, Guerrero-Preston R, Okamura J, Michailidi C, Kahn Z, Li X, Ahn J, Goldsmith M, Koch W.

Ann Surg Oncol. 2014 Sep;21(9):3124-31. doi: 10.1245/s10434-014-3661-2. Epub 2014 Mar 27.

24.

Genome-wide methylation profiling reveals Zinc finger protein 516 (ZNF516) and FK-506-binding protein 6 (FKBP6) promoters frequently methylated in cervical neoplasia, associated with HPV status and ethnicity in a Chilean population.

Brebi P, Maldonado L, Noordhuis MG, Ili C, Leal P, Garcia P, Brait M, Ribas J, Michailidi C, Perez J, Soudry E, Tapia O, Guzman P, Muñoz S, Van Neste L, Van Criekinge W, Irizarry R, Sidransky D, Roa JC, Guerrero-Preston R.

Epigenetics. 2014 Feb;9(2):308-17. doi: 10.4161/epi.27120. Epub 2013 Nov 15.

25.

Cellular FLICE-like inhibitory protein long form (c-FLIPL) overexpression is related to cervical cancer progression.

Ili CG, Brebi P, Tapia O, Sandoval A, Lopez J, Garcia P, Leal P, Sidransky D, Guerrero-Preston R, Roa JC.

Int J Gynecol Pathol. 2013 May;32(3):316-22. doi: 10.1097/PGP.0b013e31825d8064.

PMID:
23518915
26.

Cigarette smoke induces methylation of the tumor suppressor gene NISCH.

Ostrow KL, Michailidi C, Guerrero-Preston R, Hoque MO, Greenberg A, Rom W, Sidransky D.

Epigenetics. 2013 Apr;8(4):383-8. doi: 10.4161/epi.24195. Epub 2013 Mar 15.

27.

Genome-wide methylation profiling and the PI3K-AKT pathway analysis associated with smoking in urothelial cell carcinoma.

Brait M, Munari E, LeBron C, Noordhuis MG, Begum S, Michailidi C, Gonzalez-Roibon N, Maldonado L, Sen T, Guerrero-Preston R, Cope L, Parrella P, Fazio VM, Ha PK, Netto GJ, Sidransky D, Hoque MO.

Cell Cycle. 2013 Apr 1;12(7):1058-70. doi: 10.4161/cc.24050. Epub 2013 Feb 22.

28.

Phospho-ΔNp63α/microRNA feedback regulation in squamous carcinoma cells upon cisplatin exposure.

Huang Y, Kesselman D, Kizub D, Guerrero-Preston R, Ratovitski EA.

Cell Cycle. 2013 Feb 15;12(4):684-97. doi: 10.4161/cc.23598. Epub 2013 Jan 23.

29.

Phospho-ΔNp63α/SREBF1 protein interactions: bridging cell metabolism and cisplatin chemoresistance.

Huang Y, Bell LN, Okamura J, Kim MS, Mohney RP, Guerrero-Preston R, Ratovitski EA.

Cell Cycle. 2012 Oct 15;11(20):3810-27. doi: 10.4161/cc.22022. Epub 2012 Sep 5.

30.

Global tumor protein p53/p63 interactome: making a case for cisplatin chemoresistance.

Huang Y, Jeong JS, Okamura J, Sook-Kim M, Zhu H, Guerrero-Preston R, Ratovitski EA.

Cell Cycle. 2012 Jun 15;11(12):2367-79. doi: 10.4161/cc.20863. Epub 2012 Jun 15.

31.

Phospho-ΔNp63α-dependent regulation of autophagic signaling through transcription and micro-RNA modulation.

Huang Y, Guerrero-Preston R, Ratovitski EA.

Cell Cycle. 2012 Mar 15;11(6):1247-59. doi: 10.4161/cc.11.6.19670. Epub 2012 Mar 15.

32.

Clinical and public health research using methylated DNA immunoprecipitation (MeDIP): a comparison of commercially available kits to examine differential DNA methylation across the genome.

Brebi-Mieville P, Ili-Gangas C, Leal-Rojas P, Noordhuis MG, Soudry E, Perez J, Roa JC, Sidransky D, Guerrero-Preston R.

Epigenetics. 2012 Jan 1;7(1):106-12. doi: 10.4161/epi.7.1.18647. Epub 2012 Jan 1.

33.

Epigenomic biomonitors: global DNA hypomethylation as a biodosimeter of life-long environmental exposures.

Guerrero-Preston R, Herbstman J, Goldman LR.

Epigenomics. 2011 Feb;3(1):1-5. doi: 10.2217/epi.10.77. No abstract available.

34.

Cold plasma selectivity and the possibility of a paradigm shift in cancer therapy.

Keidar M, Walk R, Shashurin A, Srinivasan P, Sandler A, Dasgupta S, Ravi R, Guerrero-Preston R, Trink B.

Br J Cancer. 2011 Oct 25;105(9):1295-301. doi: 10.1038/bjc.2011.386. Epub 2011 Oct 6.

35.

NID2 and HOXA9 promoter hypermethylation as biomarkers for prevention and early detection in oral cavity squamous cell carcinoma tissues and saliva.

Guerrero-Preston R, Soudry E, Acero J, Orera M, Moreno-López L, Macía-Colón G, Jaffe A, Berdasco M, Ili-Gangas C, Brebi-Mieville P, Fu Y, Engstrom C, Irizarry RA, Esteller M, Westra W, Koch W, Califano J, Sidransky D.

Cancer Prev Res (Phila). 2011 Jul;4(7):1061-72. doi: 10.1158/1940-6207.CAPR-11-0006. Epub 2011 May 10.

36.

Genome-wide analysis of genetic alterations in testicular primary seminoma using high resolution single nucleotide polymorphism arrays.

LeBron C, Pal P, Brait M, Dasgupta S, Guerrero-Preston R, Looijenga LH, Kowalski J, Netto G, Hoque MO.

Genomics. 2011 Jun;97(6):341-9. doi: 10.1016/j.ygeno.2011.02.011. Epub 2011 Mar 2.

37.

Global DNA hypomethylation is associated with in utero exposure to cotinine and perfluorinated alkyl compounds.

Guerrero-Preston R, Goldman LR, Brebi-Mieville P, Ili-Gangas C, Lebron C, Witter FR, Apelberg BJ, Hernández-Roystacher M, Jaffe A, Halden RU, Sidransky D.

Epigenetics. 2010 Aug 16;5(6):539-46. Epub 2010 Aug 16.

38.

HCV infection and cryptogenic cirrhosis are risk factors for hepatocellular carcinoma among Latinos in New York City.

Guerrero-Preston R, Siegel A, Renz J, Vlahov D, Neugut A.

J Community Health. 2009 Dec;34(6):500-5. doi: 10.1007/s10900-009-9184-2.

PMID:
19705261
39.

Promoter DNA methylation of oncostatin m receptor-beta as a novel diagnostic and therapeutic marker in colon cancer.

Kim MS, Louwagie J, Carvalho B, Terhaar Sive Droste JS, Park HL, Chae YK, Yamashita K, Liu J, Ostrow KL, Ling S, Guerrero-Preston R, Demokan S, Yalniz Z, Dalay N, Meijer GA, Van Criekinge W, Sidransky D.

PLoS One. 2009 Aug 7;4(8):e6555. doi: 10.1371/journal.pone.0006555.

40.

Quantitative detection of Merkel cell virus in human tissues and possible mode of transmission.

Loyo M, Guerrero-Preston R, Brait M, Hoque MO, Chuang A, Kim MS, Sharma R, Liégeois NJ, Koch WM, Califano JA, Westra WH, Sidransky D.

Int J Cancer. 2010 Jun 15;126(12):2991-6. doi: 10.1002/ijc.24737.

41.

Global DNA methylation: a common early event in oral cancer cases with exposure to environmental carcinogens or viral agents.

Guerrero-Preston R, Báez A, Blanco A, Berdasco M, Fraga M, Esteller M.

P R Health Sci J. 2009 Mar;28(1):24-9.

PMID:
19266736
42.
43.
44.

Determinants of compliance with drinking water standards in rural Puerto Rico between 1996 and 2000: a multilevel approach.

Guerrero-Preston R, Norat J, Rodríguez M, Santiago L, Suárez E.

P R Health Sci J. 2008 Sep;27(3):229-35.

PMID:
18782968
45.

Previous cancer screening behavior as predictor of endoscopic colon cancer screening among women aged 50 and over, in NYC 2002.

Guerrero-Preston R, Chan C, Vlahov D, Mitchell MK, Johnson SB, Freeman H.

J Community Health. 2008 Feb;33(1):10-21.

PMID:
18080204
46.

Global DNA hypomethylation in liver cancer cases and controls: a phase I preclinical biomarker development study.

Guerrero-Preston R, Santella RM, Blanco A, Desai M, Berdasco M, Fraga M.

Epigenetics. 2007 Oct-Dec;2(4):223-6. Epub 2007 Oct 29.

PMID:
18032927
47.

The environmental health of Latino children.

Carter-Pokras O, Zambrana RE, Poppell CF, Logie LA, Guerrero-Preston R.

J Pediatr Health Care. 2007 Sep-Oct;21(5):307-14. Review.

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