Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 65


Discovery of (R)-8-(6-Methyl-4-oxo-1,4,5,6-tetrahydropyrrolo[3,4-b]pyrrol-2-yl)-3-(1-methylcyclopropyl)-2-((1-methylcyclopropyl)amino)quinazolin-4(3H)-one, a Potent and Selective Pim- 1/2 Kinase Inhibitor for Hematological Malignancies.

Wang HL, Andrews K, Booker SK, Canon J, Cee VJ, Chavez F Jr, Chen Y, Eastwood H, Guerrero N, Herberich B, Hickman D, Lanman BA, Laszlo Iii J, Lee MR, Lipford JR, Mattson B, Mohr C, Nguyen Y, Norman MH, Pettus LH, Powers D, Reed AB, Rex K, Sastri C, Tamayo NA, Wang P, Winston JT, Wu B, Wu Q, Wu T, Wurz RP, Xu Y, Zhou Y, Tasker AS.

J Med Chem. 2019 Jan 9. doi: 10.1021/acs.jmedchem.8b01733. [Epub ahead of print]


Informing physician strategies to overcome language barriers in encounters with pediatric patients.

Guerrero N, Small AL, Schwei RJ, Jacobs EA.

Patient Educ Couns. 2018 Apr;101(4):653-658. doi: 10.1016/j.pec.2017.10.018. Epub 2017 Nov 15.


MHC I presentation of Toxoplasma gondii immunodominant antigen does not require Sec22b and is regulated by antigen orientation at the vacuole membrane.

Buaillon C, Guerrero NA, Cebrian I, Blanié S, Lopez J, Bassot E, Vasseur V, Santi-Rocca J, Blanchard N.

Eur J Immunol. 2017 Jul;47(7):1160-1170. doi: 10.1002/eji.201646859. Epub 2017 Jun 8.


First Case of CD40LG Deficiency in Ecuador, Diagnosed after Whole Exome Sequencing in a Patient with Severe Cutaneous Histoplasmosis.

Pedroza LA, Guerrero N, Stray-Pedersen A, Tafur C, Macias R, Muñoz G, Akdemir ZC, Jhangiani SN, Watkin LB, Chinn IK, Lupski JR, Orange JS.

Front Pediatr. 2017 Feb 10;5:17. doi: 10.3389/fped.2017.00017. eCollection 2017.


Prion Function and Pathophysiology in Non-Mammalian Models.

Guerrero N, Meynard MM, Borgonovo J, Palma K, Concha ML, Hetz C.

Curr Mol Med. 2017;17(1):13-23. doi: 10.2174/1566524017666170220100715. Review.


Changes in neural circuitry associated with depression at pre-clinical, pre-motor and early motor phases of Parkinson's disease.

Borgonovo J, Allende-Castro C, Laliena A, Guerrero N, Silva H, Concha ML.

Parkinsonism Relat Disord. 2017 Feb;35:17-24. doi: 10.1016/j.parkreldis.2016.11.009. Epub 2016 Nov 21. Review.


Rab22a controls MHC-I intracellular trafficking and antigen cross-presentation by dendritic cells.

Cebrian I, Croce C, Guerrero NA, Blanchard N, Mayorga LS.

EMBO Rep. 2016 Dec;17(12):1753-1765. Epub 2016 Oct 10.


Music Upper Limb Therapy-Integrated: An Enriched Collaborative Approach for Stroke Rehabilitation.

Raghavan P, Geller D, Guerrero N, Aluru V, Eimicke JP, Teresi JA, Ogedegbe G, Palumbo A, Turry A.

Front Hum Neurosci. 2016 Oct 7;10:498. eCollection 2016.


Discovery of imidazopyridazines as potent Pim-1/2 kinase inhibitors.

Wurz RP, Sastri C, D'Amico DC, Herberich B, Jackson CLM, Pettus LH, Tasker AS, Wu B, Guerrero N, Lipford JR, Winston JT, Yang Y, Wang P, Nguyen Y, Andrews KL, Huang X, Lee MR, Mohr C, Zhang JD, Reid DL, Xu Y, Zhou Y, Wang HL.

Bioorg Med Chem Lett. 2016 Nov 15;26(22):5580-5590. doi: 10.1016/j.bmcl.2016.09.067. Epub 2016 Oct 1.


The viral capping enzyme nsP1: a novel target for the inhibition of chikungunya virus infection.

Delang L, Li C, Tas A, Quérat G, Albulescu IC, De Burghgraeve T, Guerrero NA, Gigante A, Piorkowski G, Decroly E, Jochmans D, Canard B, Snijder EJ, Pérez-Pérez MJ, van Hemert MJ, Coutard B, Leyssen P, Neyts J.

Sci Rep. 2016 Aug 22;6:31819. doi: 10.1038/srep31819.


Cervical and Breast Cancer Screening Among Mexican Migrant Women, 2013.

Guerrero N, Zhang X, Rangel G, Gonzalez-Fagoaga JE, Martinez-Donate A.

Prev Chronic Dis. 2016 Aug 11;13:E104. doi: 10.5888/pcd13.160036.


The mitochondrial-derived peptide humanin activates the ERK1/2, AKT, and STAT3 signaling pathways and has age-dependent signaling differences in the hippocampus.

Kim SJ, Guerrero N, Wassef G, Xiao J, Mehta HH, Cohen P, Yen K.

Oncotarget. 2016 Jul 26;7(30):46899-46912. doi: 10.18632/oncotarget.10380.


Modelling forest carbon stock changes as affected by harvest and natural disturbances. I. Comparison with countries' estimates for forest management.

Pilli R, Grassi G, Kurz WA, Viñas RA, Guerrero NH.

Carbon Balance Manag. 2016 May 23;11(1):5. eCollection 2016 Dec.


Premature loss of muscle mass and function in type 2 diabetes.

Guerrero N, Bunout D, Hirsch S, Barrera G, Leiva L, Henríquez S, De la Maza MP.

Diabetes Res Clin Pract. 2016 Jul;117:32-8. doi: 10.1016/j.diabres.2016.04.011. Epub 2016 Apr 23.


Discovery and Optimization of Quinazolinone-pyrrolopyrrolones as Potent and Orally Bioavailable Pan-Pim Kinase Inhibitors.

Pettus LH, Andrews KL, Booker SK, Chen J, Cee VJ, Chavez F Jr, Chen Y, Eastwood H, Guerrero N, Herberich B, Hickman D, Lanman BA, Laszlo J 3rd, Lee MR, Lipford JR, Mattson B, Mohr C, Nguyen Y, Norman MH, Powers D, Reed AB, Rex K, Sastri C, Tamayo N, Wang P, Winston JT, Wu B, Wu T, Wurz RP, Xu Y, Zhou Y, Tasker AS, Wang HL.

J Med Chem. 2016 Jul 14;59(13):6407-30. doi: 10.1021/acs.jmedchem.6b00610. Epub 2016 Jun 22.


Discovery and Optimization of Macrocyclic Quinoxaline-pyrrolo-dihydropiperidinones as Potent Pim-1/2 Kinase Inhibitors.

Cee VJ, Chavez F Jr, Herberich B, Lanman BA, Pettus LH, Reed AB, Wu B, Wurz RP, Andrews KL, Chen J, Hickman D, Laszlo J 3rd, Lee MR, Guerrero N, Mattson BK, Nguyen Y, Mohr C, Rex K, Sastri CE, Wang P, Wu Q, Wu T, Xu Y, Zhou Y, Winston JT, Lipford JR, Tasker AS, Wang HL.

ACS Med Chem Lett. 2016 Feb 12;7(4):408-12. doi: 10.1021/acsmedchemlett.5b00403. eCollection 2016 Apr 14.


MicroRNAs Circulate in the Hemolymph of Drosophila and Accumulate Relative to Tissue microRNAs in an Age-Dependent Manner.

Dhahbi JM, Atamna H, Li R, Yamakawa A, Guerrero N, Lam HT, Mote P, Spindler SR.

Genomics Insights. 2016 Mar 28;9:29-39. doi: 10.4137/GEI.S38147. eCollection 2016.


Assessment of hemostatic changes in a model of acute hemorrhage in dogs.

Lynch AM, deLaforcade AM, Meola D, Shih A, Bandt C, Guerrero NH, Riccó C.

J Vet Emerg Crit Care (San Antonio). 2016 May;26(3):333-43. doi: 10.1111/vec.12457. Epub 2016 Feb 18.


Chiari malformation Type I surgery in pediatric patients. Part 1: validation of an ICD-9-CM code search algorithm.

Ladner TR, Greenberg JK, Guerrero N, Olsen MA, Shannon CN, Yarbrough CK, Piccirillo JF, Anderson RC, Feldstein NA, Wellons JC 3rd, Smyth MD, Park TS, Limbrick DD Jr.

J Neurosurg Pediatr. 2016 May;17(5):519-24. doi: 10.3171/2015.10.PEDS15370. Epub 2016 Jan 22.


Correction: Cyclooxygenase-2 and Prostaglandin E2 Signaling through Prostaglandin Receptor EP-2 Favor the Development of Myocarditis during Acute Trypanosoma cruzi Infection.

Guerrero NA, Camacho M, Vila L, Íñiguez MA, Chillón-Marinas C, Cuervo H, Poveda C, Fresno M, Gironès N.

PLoS Negl Trop Dis. 2015 Oct 20;9(10):e0004175. doi: 10.1371/journal.pntd.0004175. eCollection 2015 Oct. No abstract available.


Global Analysis of Predicted G Protein-Coupled Receptor Genes in the Filamentous Fungus, Neurospora crassa.

Cabrera IE, Pacentine IV, Lim A, Guerrero N, Krystofova S, Li L, Michkov AV, Servin JA, Ahrendt SR, Carrillo AJ, Davidson LM, Barsoum AH, Cao J, Castillo R, Chen WC, Dinkchian A, Kim S, Kitada SM, Lai TH, Mach A, Malekyan C, Moua TR, Torres CR, Yamamoto A, Borkovich KA.

G3 (Bethesda). 2015 Oct 13;5(12):2729-43. doi: 10.1534/g3.115.020974.


Cyclooxygenase-2 and Prostaglandin E2 Signaling through Prostaglandin Receptor EP-2 Favor the Development of Myocarditis during Acute Trypanosoma cruzi Infection.

Guerrero NA, Camacho M, Vila L, Íñiguez MA, Chillón-Marinas C, Cuervo H, Poveda C, Fresno M, Gironès N.

PLoS Negl Trop Dis. 2015 Aug 25;9(8):e0004025. doi: 10.1371/journal.pntd.0004025. eCollection 2015. Erratum in: PLoS Negl Trop Dis. 2015 Oct;9(10):e0004175.


Community-based restaurant interventions to promote healthy eating: a systematic review.

Valdivia Espino JN, Guerrero N, Rhoads N, Simon NJ, Escaron AL, Meinen A, Nieto FJ, Martinez-Donate AP.

Prev Chronic Dis. 2015 May 21;12:E78. doi: 10.5888/pcd12.140455. Review.


Determinants of trust in health care in an older population.

Guerrero N, Mendes de Leon CF, Evans DA, Jacobs EA.

J Am Geriatr Soc. 2015 Mar;63(3):553-7. doi: 10.1111/jgs.13316. Epub 2015 Mar 6.


Discovery of 5-(1H-indol-5-yl)-1,3,4-thiadiazol-2-amines as potent PIM inhibitors.

Wu B, Wang HL, Cee VJ, Lanman BA, Nixey T, Pettus L, Reed AB, Wurz RP, Guerrero N, Sastri C, Winston J, Lipford JR, Lee MR, Mohr C, Andrews KL, Tasker AS.

Bioorg Med Chem Lett. 2015 Feb 15;25(4):775-80. doi: 10.1016/j.bmcl.2014.12.091. Epub 2015 Jan 7.


The discovery and optimization of aminooxadiazoles as potent Pim kinase inhibitors.

Wurz RP, Pettus LH, Jackson C, Wu B, Wang HL, Herberich B, Cee V, Lanman BA, Reed AB, Chavez F Jr, Nixey T, Laszlo J 3rd, Wang P, Nguyen Y, Sastri C, Guerrero N, Winston J, Lipford JR, Lee MR, Andrews KL, Mohr C, Xu Y, Zhou Y, Reid DL, Tasker AS.

Bioorg Med Chem Lett. 2015 Feb 15;25(4):847-55. doi: 10.1016/j.bmcl.2014.12.067. Epub 2015 Jan 7.


The discovery of novel 3-(pyrazin-2-yl)-1H-indazoles as potent pan-Pim kinase inhibitors.

Wang HL, Cee VJ, Chavez F Jr, Lanman BA, Reed AB, Wu B, Guerrero N, Lipford JR, Sastri C, Winston J, Andrews KL, Huang X, Lee MR, Mohr C, Xu Y, Zhou Y, Tasker AS.

Bioorg Med Chem Lett. 2015 Feb 15;25(4):834-40. doi: 10.1016/j.bmcl.2014.12.068. Epub 2014 Dec 30.


Global metabolomic profiling of acute myocarditis caused by Trypanosoma cruzi infection.

Gironès N, Carbajosa S, Guerrero NA, Poveda C, Chillón-Marinas C, Fresno M.

PLoS Negl Trop Dis. 2014 Nov 20;8(11):e3337. doi: 10.1371/journal.pntd.0003337. eCollection 2014 Nov.


Trypanosoma cruzi strains cause different myocarditis patterns in infected mice.

Rodriguez HO, Guerrero NA, Fortes A, Santi-Rocca J, Gironès N, Fresno M.

Acta Trop. 2014 Nov;139:57-66. doi: 10.1016/j.actatropica.2014.07.005. Epub 2014 Jul 11.


Daam1a mediates asymmetric habenular morphogenesis by regulating dendritic and axonal outgrowth.

Colombo A, Palma K, Armijo L, Mione M, Signore IA, Morales C, Guerrero N, Meynard MM, Pérez R, Suazo J, Marcelain K, Briones L, Härtel S, Wilson SW, Concha ML.

Development. 2013 Oct;140(19):3997-4007. doi: 10.1242/dev.091934.


Deep sequencing identifies circulating mouse miRNAs that are functionally implicated in manifestations of aging and responsive to calorie restriction.

Dhahbi JM, Spindler SR, Atamna H, Yamakawa A, Guerrero N, Boffelli D, Mote P, Martin DI.

Aging (Albany NY). 2013 Feb;5(2):130-41.


Trypanosoma cruzi infection and endothelin-1 cooperatively activate pathogenic inflammatory pathways in cardiomyocytes.

Corral RS, Guerrero NA, Cuervo H, Gironès N, Fresno M.

PLoS Negl Trop Dis. 2013;7(2):e2034. doi: 10.1371/journal.pntd.0002034. Epub 2013 Feb 7.


Cholinesterase and carboxylesterase inhibition in Planorbarius corneus exposed to binary mixtures of azinphos-methyl and chlorpyrifos.

Cacciatore LC, Guerrero NV, Cochón AC.

Aquat Toxicol. 2013 Mar 15;128-129:124-34. doi: 10.1016/j.aquatox.2012.12.005. Epub 2012 Dec 20.


Appraisal of a Leishmania major strain stably expressing mCherry fluorescent protein for both in vitro and in vivo studies of potential drugs and vaccine against cutaneous leishmaniasis.

Calvo-Álvarez E, Guerrero NA, Alvarez-Velilla R, Prada CF, Requena JM, Punzón C, Llamas MÁ, Arévalo FJ, Rivas L, Fresno M, Pérez-Pertejo Y, Balaña-Fouce R, Reguera RM.

PLoS Negl Trop Dis. 2012;6(11):e1927. doi: 10.1371/journal.pntd.0001927. Epub 2012 Nov 29.


Evolutionary plasticity of habenular asymmetry with a conserved efferent connectivity pattern.

Villalón A, Sepúlveda M, Guerrero N, Meynard MM, Palma K, Concha ML.

PLoS One. 2012;7(4):e35329. doi: 10.1371/journal.pone.0035329. Epub 2012 Apr 13.


In vivo studies on inhibition and recovery of B-esterase activities in Biomphalaria glabrata exposed to azinphos-methyl: analysis of enzyme, substrate and tissue dependence.

Kristoff G, Barrionuevo DC, Cacciatore LC, Guerrero NR, Cochón AC.

Aquat Toxicol. 2012 May 15;112-113:19-26. doi: 10.1016/j.aquatox.2012.01.016. Epub 2012 Jan 27.


Myeloid-derived suppressor cells infiltrate the heart in acute Trypanosoma cruzi infection.

Cuervo H, Guerrero NA, Carbajosa S, Beschin A, De Baetselier P, Gironès N, Fresno M.

J Immunol. 2011 Sep 1;187(5):2656-65. doi: 10.4049/jimmunol.1002928. Epub 2011 Jul 29.


Effects of the organophosphate insecticide azinphos-methyl on the reproduction and cholinesterase activity of Biomphalaria glabrata.

Kristoff G, Cacciatore LC, Guerrero NR, Cochón AC.

Chemosphere. 2011 Jul;84(5):585-91. doi: 10.1016/j.chemosphere.2011.03.058. Epub 2011 Apr 23.


Factors influencing the degradation of archival formalin-fixed paraffin-embedded tissue sections.

Xie R, Chung JY, Ylaya K, Williams RL, Guerrero N, Nakatsuka N, Badie C, Hewitt SM.

J Histochem Cytochem. 2011 Apr;59(4):356-65. doi: 10.1369/0022155411398488. Epub 2011 Feb 10.


Assessment of the acute toxicity of the organochlorine pesticide endosulfan in Cichlasoma dimerus (Teleostei, Perciformes).

Da Cuña RH, Rey Vázquez G, Piol MN, Guerrero NV, Maggese MC, Lo Nostro FL.

Ecotoxicol Environ Saf. 2011 May;74(4):1065-73. doi: 10.1016/j.ecoenv.2011.02.002. Epub 2011 Mar 5.


Investigating arsenic bioavailability and bioaccumulation by the freshwater oligochaete Lumbriculus variegatus.

Nasi M, Piol MN, Di Risio C, Guerrero NR.

Arch Environ Contam Toxicol. 2011 Oct;61(3):426-34. doi: 10.1007/s00244-010-9639-6. Epub 2011 Feb 1.


Effect of Helicobacter pylori infection on growth velocity of school-age Andean children.

Goodman KJ, Correa P, Mera R, Yepez MC, Cerón C, Campo C, Guerrero N, Sierra MS, Bravo LE.

Epidemiology. 2011 Jan;22(1):118-26. doi: 10.1097/EDE.0b013e3181fe7e31. Erratum in: Epidemiology. 2011 May;22(3):447.


Inhibition of cholinesterases and carboxylesterases of two invertebrate species, Biomphalaria glabrata and Lumbriculus variegatus, by the carbamate pesticide carbaryl.

Kristoff G, Guerrero NR, Cochón AC.

Aquat Toxicol. 2010 Jan 31;96(2):115-23. doi: 10.1016/j.aquatox.2009.10.001. Epub 2009 Oct 8.


The implementation and preliminary evaluation of an ART strategy in Mexico: a country example.

Hermosillo VH, Quintero LE, Guerrero ND, Suárez DD, Hernández MJ, Holmgren CJ.

J Appl Oral Sci. 2009;17 Suppl:114-21.


Zebrafish and medaka: model organisms for a comparative developmental approach of brain asymmetry.

Signore IA, Guerrero N, Loosli F, Colombo A, Villalón A, Wittbrodt J, Concha ML.

Philos Trans R Soc Lond B Biol Sci. 2009 Apr 12;364(1519):991-1003. doi: 10.1098/rstb.2008.0260.


Factors in tissue handling and processing that impact RNA obtained from formalin-fixed, paraffin-embedded tissue.

Chung JY, Braunschweig T, Williams R, Guerrero N, Hoffmann KM, Kwon M, Song YK, Libutti SK, Hewitt SM.

J Histochem Cytochem. 2008 Nov;56(11):1033-42. doi: 10.1369/jhc.2008.951863. Epub 2008 Aug 18.


Use of a patch containing heat-labile toxin from Escherichia coli against travellers' diarrhoea: a phase II, randomised, double-blind, placebo-controlled field trial.

Frech SA, Dupont HL, Bourgeois AL, McKenzie R, Belkind-Gerson J, Figueroa JF, Okhuysen PC, Guerrero NH, Martinez-Sandoval FG, Meléndez-Romero JH, Jiang ZD, Asturias EJ, Halpern J, Torres OR, Hoffman AS, Villar CP, Kassem RN, Flyer DC, Andersen BH, Kazempour K, Breisch SA, Glenn GM.

Lancet. 2008 Jun 14;371(9629):2019-25. doi: 10.1016/S0140-6736(08)60839-9.


Role of Trypanosoma cruzi autoreactive T cells in the generation of cardiac pathology.

Gironès N, Carrasco-Marin E, Cuervo H, Guerrero NA, Sanoja C, John S, Flores-Herráez R, Fernández-Prieto L, Chico-Calero I, Salgado H, Carrión J, Fresno M.

Ann N Y Acad Sci. 2007 Jun;1107:434-44.


Potential use of glycogen level as biomarker of chemical stress in Biomphalaria glabrata.

Ansaldo M, Nahabedian DE, Holmes-Brown E, Agote M, Ansay CV, Guerrero NR, Wider EA.

Toxicology. 2006 Jul 5;224(1-2):119-27. Epub 2006 May 2.


Supplemental Content

Loading ...
Support Center