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Items: 22

1.

IL-22 Binding Protein Promotes the Disease Process in Multiple Sclerosis.

Lindahl H, Guerreiro-Cacais AO, Bedri SK, Linnerbauer M, Lindén M, Abdelmagid N, Tandre K, Hollins C, Irving L, Glover C, Jones C, Alfredsson L, Rönnblom L, Kockum I, Khademi M, Jagodic M, Olsson T.

J Immunol. 2019 Jul 10. pii: ji1900400. doi: 10.4049/jimmunol.1900400. [Epub ahead of print]

PMID:
31292217
2.

Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis.

Falcão AM, van Bruggen D, Marques S, Meijer M, Jäkel S, Agirre E, Samudyata, Floriddia EM, Vanichkina DP, Ffrench-Constant C, Williams A, Guerreiro-Cacais AO, Castelo-Branco G.

Nat Med. 2018 Dec;24(12):1837-1844. doi: 10.1038/s41591-018-0236-y. Epub 2018 Nov 12.

3.

Fatal demyelinating disease is induced by monocyte-derived macrophages in the absence of TGF-β signaling.

Lund H, Pieber M, Parsa R, Grommisch D, Ewing E, Kular L, Han J, Zhu K, Nijssen J, Hedlund E, Needhamsen M, Ruhrmann S, Guerreiro-Cacais AO, Berglund R, Forteza MJ, Ketelhuth DFJ, Butovsky O, Jagodic M, Zhang XM, Harris RA.

Nat Immunol. 2018 May;19(5):1-7. doi: 10.1038/s41590-018-0091-5. Epub 2018 Apr 16.

PMID:
29662171
4.

VAV1 regulates experimental autoimmune arthritis and is associated with anti-CCP negative rheumatoid arthritis.

Guerreiro-Cacais AO, Norin U, Gyllenberg A, Berglund R, Beyeen AD; Rheumatoid Arthritis Consortium International (RACI), Petit-Teixeira E, Cornélis F, Saoudi A, Fournié GJ, Holmdahl R, Alfredsson L, Klareskog L, Jagodic M, Olsson T, Kockum I, Padyukov L.

Genes Immun. 2017 Mar;18(2):109. doi: 10.1038/gene.2017.7. No abstract available.

PMID:
28446790
5.

Functional genomics analysis of vitamin D effects on CD4+ T cells in vivo in experimental autoimmune encephalomyelitis ‬.

Zeitelhofer M, Adzemovic MZ, Gomez-Cabrero D, Bergman P, Hochmeister S, N'diaye M, Paulson A, Ruhrmann S, Almgren M, Tegnér JN, Ekström TJ, Guerreiro-Cacais AO, Jagodic M.

Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):E1678-E1687. doi: 10.1073/pnas.1615783114. Epub 2017 Feb 14.

6.

VAV1 regulates experimental autoimmune arthritis and is associated with anti-CCP negative rheumatoid arthritis.

Guerreiro-Cacais AO, Norin U, Gyllenberg A, Berglund R, Beyeen AD; Rheumatoid Arthritis Consortium International (RACI), Petit-Teixeira E, Cornélis F, Saoudi A, Fournié GJ, Holmdahl R, Alfredsson L, Klareskog L, Jagodic M, Olsson T, Kockum I, Padyukov L.

Genes Immun. 2017 Jan;18(1):48-56. doi: 10.1038/gene.2016.49. Epub 2017 Jan 5. Erratum in: Genes Immun. 2017 Mar;18(2):109.

PMID:
28053322
7.

IL-22 binding protein regulates murine skin inflammation.

Lindahl H, Martini E, Brauner S, Nikamo P, Gallais Serezal I, Guerreiro-Cacais AO, Jagodic M, Eidsmo L, Ståhle M, Olsson T.

Exp Dermatol. 2017 May;26(5):444-446. doi: 10.1111/exd.13225. Epub 2017 Mar 23. No abstract available.

PMID:
27676439
8.

Anoctamin 2 identified as an autoimmune target in multiple sclerosis.

Ayoglu B, Mitsios N, Kockum I, Khademi M, Zandian A, Sjöberg R, Forsström B, Bredenberg J, Lima Bomfim I, Holmgren E, Grönlund H, Guerreiro-Cacais AO, Abdelmagid N, Uhlén M, Waterboer T, Alfredsson L, Mulder J, Schwenk JM, Olsson T, Nilsson P.

Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):2188-93. doi: 10.1073/pnas.1518553113. Epub 2016 Feb 9.

9.

Translational utility of experimental autoimmune encephalomyelitis: recent developments.

Guerreiro-Cacais AO, Laaksonen H, Flytzani S, N'diaye M, Olsson T, Jagodic M.

J Inflamm Res. 2015 Nov 13;8:211-25. doi: 10.2147/JIR.S76707. eCollection 2015. Review.

10.

Rat bone marrow-derived dendritic cells generated with GM-CSF/IL-4 or FLT3L exhibit distinct phenotypical and functional characteristics.

N'diaye M, Warnecke A, Flytzani S, Abdelmagid N, Ruhrmann S, Olsson T, Jagodic M, Harris RA, Guerreiro-Cacais AO.

J Leukoc Biol. 2016 Mar;99(3):437-46. doi: 10.1189/jlb.1AB0914-433RR. Epub 2015 Oct 29.

PMID:
26516183
11.

MOG-induced experimental autoimmune encephalomyelitis in the rat species triggers anti-neurofascin antibody response that is genetically regulated.

Flytzani S, Guerreiro-Cacais AO, N'diaye M, Lindner M, Linington C, Meinl E, Stridh P, Jagodic M, Olsson T.

J Neuroinflammation. 2015 Oct 29;12:194. doi: 10.1186/s12974-015-0417-2.

12.

Acute treatment with valproic acid and l-thyroxine ameliorates clinical signs of experimental autoimmune encephalomyelitis and prevents brain pathology in DA rats.

Castelo-Branco G, Stridh P, Guerreiro-Cacais AO, Adzemovic MZ, Falcão AM, Marta M, Berglund R, Gillett A, Hamza KH, Lassmann H, Hermanson O, Jagodic M.

Neurobiol Dis. 2014 Nov;71:220-33. doi: 10.1016/j.nbd.2014.08.019. Epub 2014 Aug 19.

13.

The multiple sclerosis risk gene IL22RA2 contributes to a more severe murine autoimmune neuroinflammation.

Laaksonen H, Guerreiro-Cacais AO, Adzemovic MZ, Parsa R, Zeitelhofer M, Jagodic M, Olsson T.

Genes Immun. 2014 Oct;15(7):457-65. doi: 10.1038/gene.2014.36. Epub 2014 Jul 10.

PMID:
25008863
14.

Anti-MOG antibodies are under polygenic regulation with the most significant control coming from the C-type lectin-like gene locus.

Flytzani S, Stridh P, Guerreiro-Cacais AO, Marta M, Hedreul MT, Jagodic M, Olsson T.

Genes Immun. 2013 Oct;14(7):409-19. doi: 10.1038/gene.2013.33. Epub 2013 Jun 20.

PMID:
23784360
15.

Combined sequence-based and genetic mapping analysis of complex traits in outbred rats.

Rat Genome Sequencing and Mapping Consortium, Baud A, Hermsen R, Guryev V, Stridh P, Graham D, McBride MW, Foroud T, Calderari S, Diez M, Ockinger J, Beyeen AD, Gillett A, Abdelmagid N, Guerreiro-Cacais AO, Jagodic M, Tuncel J, Norin U, Beattie E, Huynh N, Miller WH, Koller DL, Alam I, Falak S, Osborne-Pellegrin M, Martinez-Membrives E, Canete T, Blazquez G, Vicens-Costa E, Mont-Cardona C, Diaz-Moran S, Tobena A, Hummel O, Zelenika D, Saar K, Patone G, Bauerfeind A, Bihoreau MT, Heinig M, Lee YA, Rintisch C, Schulz H, Wheeler DA, Worley KC, Muzny DM, Gibbs RA, Lathrop M, Lansu N, Toonen P, Ruzius FP, de Bruijn E, Hauser H, Adams DJ, Keane T, Atanur SS, Aitman TJ, Flicek P, Malinauskas T, Jones EY, Ekman D, Lopez-Aumatell R, Dominiczak AF, Johannesson M, Holmdahl R, Olsson T, Gauguier D, Hubner N, Fernandez-Teruel A, Cuppen E, Mott R, Flint J.

Nat Genet. 2013 Jul;45(7):767-75. doi: 10.1038/ng.2644. Epub 2013 May 26.

16.

Strain influences on inflammatory pathway activation, cell infiltration and complement cascade after traumatic brain injury in the rat.

Al Nimer F, Lindblom R, Ström M, Guerreiro-Cacais AO, Parsa R, Aeinehband S, Mathiesen T, Lidman O, Piehl F.

Brain Behav Immun. 2013 Jan;27(1):109-22. doi: 10.1016/j.bbi.2012.10.002. Epub 2012 Oct 6.

PMID:
23044177
17.

The calcitonin receptor gene is a candidate for regulation of susceptibility to herpes simplex type 1 neuronal infection leading to encephalitis in rat.

Abdelmagid N, Bereczky-Veress B, Guerreiro-Cacais AO, Bergman P, Luhr KM, Bergström T, Sköldenberg B, Piehl F, Olsson T, Diez M.

PLoS Pathog. 2012;8(6):e1002753. doi: 10.1371/journal.ppat.1002753. Epub 2012 Jun 28.

18.

Syntaxin 11 marks a distinct intracellular compartment recruited to the immunological synapse of NK cells to colocalize with cytotoxic granules.

Dabrazhynetskaya A, Ma J, Guerreiro-Cacais AO, Arany Z, Rudd E, Henter JI, Karre K, Levitskaya J, Levitsky V.

J Cell Mol Med. 2012 Jan;16(1):129-41. doi: 10.1111/j.1582-4934.2011.01280.x.

19.

B cell receptor triggering sensitizes human B cells to TRAIL-induced apoptosis.

Guerreiro-Cacais AO, Levitskaya J, Levitsky V.

J Leukoc Biol. 2010 Nov;88(5):937-45. doi: 10.1189/jlb.0510246. Epub 2010 Aug 13.

PMID:
20709941
20.

A molecular link between malaria and Epstein-Barr virus reactivation.

Chêne A, Donati D, Guerreiro-Cacais AO, Levitsky V, Chen Q, Falk KI, Orem J, Kironde F, Wahlgren M, Bejarano MT.

PLoS Pathog. 2007 Jun;3(6):e80.

21.
22.

Capacity of Epstein-Barr virus to infect monocytes and inhibit their development into dendritic cells is affected by the cell type supporting virus replication.

Guerreiro-Cacais AO, Li L, Donati D, Bejarano MT, Morgan A, Masucci MG, Hutt-Fletcher L, Levitsky V.

J Gen Virol. 2004 Oct;85(Pt 10):2767-78.

PMID:
15448337

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