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Items: 19

1.

Glutamatergic and dopaminergic modulation of cortico-striatal circuits probed by dynamic calcium imaging of networks reconstructed in microfluidic chips.

Lassus B, Naudé J, Faure P, Guedin D, Von Boxberg Y, Mannoury la Cour C, Millan MJ, Peyrin JM.

Sci Rep. 2018 Nov 29;8(1):17461. doi: 10.1038/s41598-018-35802-9.

2.

Parkin maintains mitochondrial levels of the protective Parkinson's disease-related enzyme 17-β hydroxysteroid dehydrogenase type 10.

Bertolin G, Jacoupy M, Traver S, Ferrando-Miguel R, Saint Georges T, Grenier K, Ardila-Osorio H, Muriel MP, Takahashi H, Lees AJ, Gautier C, Guedin D, Coge F, Fon EA, Brice A, Corti O.

Cell Death Differ. 2015 Oct;22(10):1563-76. doi: 10.1038/cdd.2014.224. Epub 2015 Jan 16.

3.

New potent calcimimetics: II. Discovery of benzothiazole trisubstituted ureas.

Deprez P, Temal T, Jary H, Auberval M, Lively S, Guédin D, Vevert JP.

Bioorg Med Chem Lett. 2013 Apr 15;23(8):2455-9. doi: 10.1016/j.bmcl.2013.01.077. Epub 2013 Feb 8.

PMID:
23499504
4.

New potent calcimimetics: I. Discovery of a series of novel trisubstituted ureas.

Temal T, Jary H, Auberval M, Lively S, Guédin D, Vevert JP, Deprez P.

Bioorg Med Chem Lett. 2013 Apr 15;23(8):2451-4. doi: 10.1016/j.bmcl.2013.01.078. Epub 2013 Jan 29.

PMID:
23465611
5.

Identification of a 4-(hydroxymethyl)diarylhydantoin as a selective androgen receptor modulator.

Nique F, Hebbe S, Triballeau N, Peixoto C, Lefrançois JM, Jary H, Alvey L, Manioc M, Housseman C, Klaassen H, Van Beeck K, Guédin D, Namour F, Minet D, Van der Aar E, Feyen J, Fletcher S, Blanqué R, Robin-Jagerschmidt C, Deprez P.

J Med Chem. 2012 Oct 11;55(19):8236-47. doi: 10.1021/jm300281x. Epub 2012 Sep 25.

PMID:
22957947
6.

Discovery of diarylhydantoins as new selective androgen receptor modulators.

Nique F, Hebbe S, Peixoto C, Annoot D, Lefrançois JM, Duval E, Michoux L, Triballeau N, Lemoullec JM, Mollat P, Thauvin M, Prangé T, Minet D, Clément-Lacroix P, Robin-Jagerschmidt C, Fleury D, Guédin D, Deprez P.

J Med Chem. 2012 Oct 11;55(19):8225-35. doi: 10.1021/jm300249m. Epub 2012 Sep 25.

PMID:
22897611
7.

Nicotinic receptors: allosteric transitions and therapeutic targets in the nervous system.

Taly A, Corringer PJ, Guedin D, Lestage P, Changeux JP.

Nat Rev Drug Discov. 2009 Sep;8(9):733-50. doi: 10.1038/nrd2927. Review.

PMID:
19721446
8.

The confirmation rate of primary hits: a predictive model.

Fogel P, Collette P, Dupront A, Garyantes T, Guédin D.

J Biomol Screen. 2002 Jun;7(3):175-90.

PMID:
12097182
9.

Molecular modeling of the GABA/GABA(B) receptor complex.

Bernard P, Guedin D, Hibert M.

J Med Chem. 2001 Jan 4;44(1):27-35.

PMID:
11141085
10.
11.

A live-cell assay for studying extracellular and intracellular endothelin-converting enzyme activity.

Parnot C, Le Moullec JM, Cousin MA, Guédin D, Corvol P, Pinet F.

Hypertension. 1997 Oct;30(4):837-44.

PMID:
9336381
12.

High affinity binding of pyrethroids to the alpha subunit of brain sodium channels.

Trainer VL, McPhee JC, Boutelet-Bochan H, Baker C, Scheuer T, Babin D, Demoute JP, Guedin D, Catterall WA.

Mol Pharmacol. 1997 Apr;51(4):651-7.

PMID:
9106631
13.

Conversion of big-endothelin-1 elicits an endothelin ETA receptor-mediated response in endothelial cells.

N'Diaye N, Pueyo ME, Battle T, Ossart C, Guédin D, Michel JB.

Eur J Pharmacol. 1997 Mar 5;321(3):387-96.

PMID:
9085052
14.

Direct block of voltage-sensitive sodium channels by genistein, a tyrosine kinase inhibitor.

Paillart C, Carlier E, Guedin D, Dargent B, Couraud F.

J Pharmacol Exp Ther. 1997 Feb;280(2):521-6.

PMID:
9023259
15.

Interaction of endothelin-1 with cloned bovine ETA receptors: biochemical parameters and functional consequences.

Desmarets J, Gresser O, Guedin D, Frelin C.

Biochemistry. 1996 Nov 26;35(47):14868-75.

PMID:
8942650
16.

Et-1 and Et-3 actions mediated by cloned ETA endothelin receptors exhibit different sensitivities to BQ-123.

Gresser O, Chayard D, Herbert D, Cousin MA, Le Moullec JM, Bouattane F, Guedin D, Frelin C.

Biochem Biophys Res Commun. 1996 Jul 5;224(1):169-71.

PMID:
8694806
17.

Properties of an endothelin-3-sensitive Eta-like endothelin receptor in brain capillary endothelial cells.

Vigne P, Desmarets J, Guedin D, Frelin C.

Biochem Biophys Res Commun. 1996 Mar 27;220(3):839-42.

PMID:
8607852
18.

Why are circulating concentrations of endothelin-1 so low?

Frelin C, Guedin D.

Cardiovasc Res. 1994 Nov;28(11):1613-22. Review.

PMID:
7842453
19.

Neurotoxin binding and allosteric modulation at receptor sites 2 and 5 on purified and reconstituted rat brain sodium channels.

Trainer VL, Moreau E, Guedin D, Baden DG, Catterall WA.

J Biol Chem. 1993 Aug 15;268(23):17114-9.

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