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Items: 6


Significantly altered peripheral blood cell DNA methylation profile as a result of immediate effect of metformin use in healthy individuals.

Elbere I, Silamikelis I, Ustinova M, Kalnina I, Zaharenko L, Peculis R, Konrade I, Ciuculete DM, Zhukovsky C, Gudra D, Radovica-Spalvina I, Fridmanis D, Pirags V, Schiöth HB, Klovins J.

Clin Epigenetics. 2018 Dec 13;10(1):156. doi: 10.1186/s13148-018-0593-x.


Association of metformin administration with gut microbiome dysbiosis in healthy volunteers.

Elbere I, Kalnina I, Silamikelis I, Konrade I, Zaharenko L, Sekace K, Radovica-Spalvina I, Fridmanis D, Gudra D, Pirags V, Klovins J.

PLoS One. 2018 Sep 27;13(9):e0204317. doi: 10.1371/journal.pone.0204317. eCollection 2018.


A widely used sampling device in colorectal cancer screening programmes allows for large-scale microbiome studies.

Gudra D, Shoaie S, Fridmanis D, Klovins J, Wefer H, Silamikelis I, Peculis R, Kalnina I, Elbere I, Radovica-Spalvina I, Hultcrantz R, Šķenders Ģ, Leja M, Engstrand L.

Gut. 2019 Sep;68(9):1723-1725. doi: 10.1136/gutjnl-2018-316225. Epub 2018 Sep 21. No abstract available.


Microbiome symbionts and diet diversity incur costs on the immune system of insect larvae.

Krams IA, Kecko S, Jõers P, Trakimas G, Elferts D, Krams R, Luoto S, Rantala MJ, Inashkina I, Gudrā D, Fridmanis D, Contreras-Garduño J, Grantiņa-Ieviņa L, Krama T.

J Exp Biol. 2017 Nov 15;220(Pt 22):4204-4212. doi: 10.1242/jeb.169227. Epub 2017 Sep 22.


The effects of ibuprofen on activated sludge: Shift in bacterial community structure and resistance to ciprofloxacin.

Davids M, Gudra D, Radovica-Spalvina I, Fridmanis D, Bartkevics V, Muter O.

J Hazard Mater. 2017 Oct 15;340:291-299. doi: 10.1016/j.jhazmat.2017.06.065. Epub 2017 Jun 28.


Removal of pharmaceuticals from municipal wastewaters at laboratory scale by treatment with activated sludge and biostimulation.

Muter O, P Erkons I, Selga T, Berzins A, Gudra D, Radovica-Spalvina I, Fridmanis D, Bartkevics V.

Sci Total Environ. 2017 Apr 15;584-585:402-413. doi: 10.1016/j.scitotenv.2017.01.023. Epub 2017 Jan 24.


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