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Items: 10

1.

In silico and in vitro immunogenicity assessment of B-domain-modified recombinant factor VIII molecules.

Bartholdy C, Reedtz-Runge SL, Wang J, Hjerrild Zeuthen L, Gruhler A, Gudme CN, Lamberth K.

Haemophilia. 2018 Sep;24(5):e354-e362. doi: 10.1111/hae.13555. Epub 2018 Jul 19.

PMID:
30024643
2.

Increased basement membrane turnover and strongly attenuated interstitial matrix turnover is a key pathological feature of haemophilia.

Manon-Jensen T, Hua BL, Olsen EHN, Sun S, Gudme CN, Li J, Lei W, Vandahl B, Roepstorff K, Kjelgaard-Hansen M, Zhao Y, Karsdal MA.

Haemophilia. 2017 Nov;23(6):e515-e518. doi: 10.1111/hae.13329. Epub 2017 Aug 29. No abstract available.

PMID:
28851078
3.

Serological biomarkers detect active joint destruction and inflammation in patients with haemophilic arthropathy.

Hua B, Olsen EHN, Sun S, Gudme CN, Wang L, Vandahl B, Roepstorff K, Kjelgaard-Hansen M, Sørensen BB, Zhao Y, Karsdal MA, Manon-Jensen T.

Haemophilia. 2017 Jul;23(4):e294-e300. doi: 10.1111/hae.13196. Epub 2017 Apr 24.

PMID:
28439941
4.

Post hoc assessment of the immunogenicity of bioengineered factor VIIa demonstrates the use of preclinical tools.

Lamberth K, Reedtz-Runge SL, Simon J, Klementyeva K, Pandey GS, Padkjær SB, Pascal V, León IR, Gudme CN, Buus S, Sauna ZE.

Sci Transl Med. 2017 Jan 11;9(372). pii: eaag1286. doi: 10.1126/scitranslmed.aag1286.

PMID:
28077675
5.

High-affinity von Willebrand factor binding does not affect the anatomical or hepatocellular distribution of factor VIII in rats.

Øie CI, Roepstorff K, Behrens C, Bøggild Kristensen J, Karpf DM, Bolt G, Gudme CN, Kjalke M, Smedsrød B, Appa RS.

J Thromb Haemost. 2016 Sep;14(9):1803-13. doi: 10.1111/jth.13406. Epub 2016 Aug 24.

6.

A novel B-domain O-glycoPEGylated FVIII (N8-GP) demonstrates full efficacy and prolonged effect in hemophilic mice models.

Stennicke HR, Kjalke M, Karpf DM, Balling KW, Johansen PB, Elm T, Øvlisen K, Möller F, Holmberg HL, Gudme CN, Persson E, Hilden I, Pelzer H, Rahbek-Nielsen H, Jespersgaard C, Bogsnes A, Pedersen AA, Kristensen AK, Peschke B, Kappers W, Rode F, Thim L, Tranholm M, Ezban M, Olsen EH, Bjørn SE.

Blood. 2013 Mar 14;121(11):2108-16. doi: 10.1182/blood-2012-01-407494. Epub 2013 Jan 18.

7.

KIR2DS1-positive NK cells mediate alloresponse against the C2 HLA-KIR ligand group in vitro.

Chewning JH, Gudme CN, Hsu KC, Selvakumar A, Dupont B.

J Immunol. 2007 Jul 15;179(2):854-68.

8.
9.

Maxi K+ channels co-localised with CFTR in the apical membrane of an exocrine gland acinus: possible involvement in secretion.

Sørensen JB, Nielsen MS, Gudme CN, Larsen EH, Nielsen R.

Pflugers Arch. 2001 Apr;442(1):1-11.

PMID:
11374055
10.

Effect of alpha1-adrenergic stimulation of Cl- secretion and signal transduction in exocrine glands (Rana esculenta).

Gudme CN, Nielsen MS, Nielsen R.

Acta Physiol Scand. 2000 Jun;169(2):173-82.

PMID:
10848648

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