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Items: 1 to 50 of 131

1.

Genetic signature to provide robust risk assessment of psoriatic arthritis development in psoriasis patients.

Patrick MT, Stuart PE, Raja K, Gudjonsson JE, Tejasvi T, Yang J, Chandran V, Das S, Callis-Duffin K, Ellinghaus E, Enerbäck C, Esko T, Franke A, Kang HM, Krueger GG, Lim HW, Rahman P, Rosen CF, Weidinger S, Weichenthal M, Wen X, Voorhees JJ, Abecasis GR, Gladman DD, Nair RP, Elder JT, Tsoi LC.

Nat Commun. 2018 Oct 9;9(1):4178. doi: 10.1038/s41467-018-06672-6.

2.

IL-17 integrates multiple self-reinforcing, feed-forward mechanisms through the RNA binding protein Arid5a.

Amatya N, Childs EE, Cruz JA, Aggor FEY, Garg AV, Berman AJ, Gudjonsson JE, Atasoy U, Gaffen SL.

Sci Signal. 2018 Oct 9;11(551). pii: eaat4617. doi: 10.1126/scisignal.aat4617.

PMID:
30301788
3.

Advances in Cutaneous Lupus Erythematosus and Dermatomyositis: A report from the 4th International Conference on Cutaneous Lupus Erythematosus An ongoing need for international consensus and collaborations.

Concha JSS, Patsatsi A, Marshak-Rothstein A, Liu ML, Sinha AA, Lee LA, Merola JF, Jabbari A, Gudjonsson JE, Chasset F, Jarrett P, Chong B, Arkin L, Fernandez AP, Caproni M, Greenberg SA, Kim HJ, Pearson DR, Femia A, Vleugels RA, Fiorentino D, Fujimoto M, Wenzel J, Werth VP.

J Invest Dermatol. 2018 Sep 19. pii: S0022-202X(18)32582-X. doi: 10.1016/j.jid.2018.08.017. [Epub ahead of print] No abstract available.

PMID:
30243657
4.

Photosensitivity and type I IFN responses in cutaneous lupus are driven by epidermal-derived interferon kappa.

Sarkar MK, Hile GA, Tsoi LC, Xing X, Liu J, Liang Y, Berthier CC, Swindell WR, Patrick MT, Shao S, Tsou PS, Uppala R, Beamer MA, Srivastava A, Bielas SL, Harms PW, Getsios S, Elder JT, Voorhees JJ, Gudjonsson JE, Kahlenberg JM.

Ann Rheum Dis. 2018 Nov;77(11):1653-1664. doi: 10.1136/annrheumdis-2018-213197. Epub 2018 Jul 18.

PMID:
30021804
5.

Meta-analysis of RNA sequencing datasets reveals an association between TRAJ23, psoriasis, and IL-17A.

Merleev AA, Marusina AI, Ma C, Elder JT, Tsoi LC, Raychaudhuri SP, Weidinger S, Wang EA, Adamopoulos IE, Luxardi G, Gudjonsson JE, Shimoda M, Maverakis E.

JCI Insight. 2018 Jul 12;3(13). pii: 120682. doi: 10.1172/jci.insight.120682. [Epub ahead of print]

6.

Dietary Recommendations for Adults With Psoriasis or Psoriatic Arthritis From the Medical Board of the National Psoriasis Foundation: A Systematic Review.

Ford AR, Siegel M, Bagel J, Cordoro KM, Garg A, Gottlieb A, Green LJ, Gudjonsson JE, Koo J, Lebwohl M, Liao W, Mandelin AM 2nd, Markenson JA, Mehta N, Merola JF, Prussick R, Ryan C, Schwartzman S, Siegel EL, Van Voorhees AS, Wu JJ, Armstrong AW.

JAMA Dermatol. 2018 Aug 1;154(8):934-950. doi: 10.1001/jamadermatol.2018.1412.

PMID:
29926091
7.

Dystrophic calcifications point the way-Unusual and early diagnostic clue of Conradi-Hünermann-Happle syndrome.

Yu K, Reid AT, Chen SJT, Patel RM, Donn SM, Gudjonsson JE, Lowe L.

JAAD Case Rep. 2018 Mar 31;4(4):333-336. doi: 10.1016/j.jdcr.2017.10.018. eCollection 2018 May. No abstract available.

8.

RNA-Seq Analysis of IL-1B and IL-36 Responses in Epidermal Keratinocytes Identifies a Shared MyD88-Dependent Gene Signature.

Swindell WR, Beamer MA, Sarkar MK, Loftus S, Fullmer J, Xing X, Ward NL, Tsoi LC, Kahlenberg MJ, Liang Y, Gudjonsson JE.

Front Immunol. 2018 Jan 29;9:80. doi: 10.3389/fimmu.2018.00080. eCollection 2018.

9.

RNA-seq identifies a diminished differentiation gene signature in primary monolayer keratinocytes grown from lesional and uninvolved psoriatic skin.

Swindell WR, Sarkar MK, Liang Y, Xing X, Baliwag J, Elder JT, Johnston A, Ward NL, Gudjonsson JE.

Sci Rep. 2017 Dec 22;7(1):18045. doi: 10.1038/s41598-017-18404-9.

10.

Research Techniques Made Simple: Murine Models of Human Psoriasis.

Hawkes JE, Adalsteinsson JA, Gudjonsson JE, Ward NL.

J Invest Dermatol. 2018 Jan;138(1):e1-e8. doi: 10.1016/j.jid.2017.10.013.

PMID:
29273150
11.

Unsuspected lymphomatoid granulomatosis in a patient with antisynthetase syndrome.

Skala SL, Hristov AC, Gudjonsson JE, Chan MP.

Cutis. 2017 Oct;100(4):E22-E26.

PMID:
29136066
12.

IFN-γ and TNF-α synergism may provide a link between psoriasis and inflammatory atherogenesis.

Mehta NN, Teague HL, Swindell WR, Baumer Y, Ward NL, Xing X, Baugous B, Johnston A, Joshi AA, Silverman J, Barnes DH, Wolterink L, Nair RP, Stuart PE, Playford M, Voorhees JJ, Sarkar MK, Elder JT, Gallagher K, Ganesh SK, Gudjonsson JE.

Sci Rep. 2017 Oct 23;7(1):13831. doi: 10.1038/s41598-017-14365-1.

13.

Transcriptional determinants of individualized inflammatory responses at anatomically separate sites.

Tsoi LC, Yang J, Liang Y, Sarkar MK, Xing X, Beamer MA, Aphale A, Raja K, Kozlow JH, Getsios S, Voorhees JJ, Kahlenberg JM, Elder JT, Gudjonsson JE.

J Allergy Clin Immunol. 2018 Feb;141(2):805-808. doi: 10.1016/j.jaci.2017.07.054. Epub 2017 Oct 13. No abstract available.

PMID:
29031600
14.

Exome-wide association study reveals novel psoriasis susceptibility locus at TNFSF15 and rare protective alleles in genes contributing to type I IFN signalling.

Dand N, Mucha S, Tsoi LC, Mahil SK, Stuart PE, Arnold A, Baurecht H, Burden AD, Callis Duffin K, Chandran V, Curtis CJ, Das S, Ellinghaus D, Ellinghaus E, Enerback C, Esko T, Gladman DD, Griffiths CEM, Gudjonsson JE, Hoffman P, Homuth G, Hüffmeier U, Krueger GG, Laudes M, Lee SH, Lieb W, Lim HW, Löhr S, Mrowietz U, Müller-Nurayid M, Nöthen M, Peters A, Rahman P, Reis A, Reynolds NJ, Rodriguez E, Schmidt CO, Spain SL, Strauch K, Tejasvi T, Voorhees JJ, Warren RB, Weichenthal M, Weidinger S, Zawistowski M, Nair RP, Capon F, Smith CH, Trembath RC, Abecasis GR, Elder JT, Franke A, Simpson MA, Barker JN.

Hum Mol Genet. 2017 Nov 1;26(21):4301-4313. doi: 10.1093/hmg/ddx328.

15.

Scleroderma keratinocytes promote fibroblast activation independent of transforming growth factor beta.

McCoy SS, Reed TJ, Berthier CC, Tsou PS, Liu J, Gudjonsson JE, Khanna D, Kahlenberg JM.

Rheumatology (Oxford). 2017 Nov 1;56(11):1970-1981. doi: 10.1093/rheumatology/kex280.

PMID:
28968684
16.

Psoriasis: a mixed autoimmune and autoinflammatory disease.

Liang Y, Sarkar MK, Tsoi LC, Gudjonsson JE.

Curr Opin Immunol. 2017 Dec;49:1-8. doi: 10.1016/j.coi.2017.07.007. Epub 2017 Jul 22. Review.

PMID:
28738209
17.

Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants.

Tsoi LC, Stuart PE, Tian C, Gudjonsson JE, Das S, Zawistowski M, Ellinghaus E, Barker JN, Chandran V, Dand N, Duffin KC, Enerbäck C, Esko T, Franke A, Gladman DD, Hoffmann P, Kingo K, Kõks S, Krueger GG, Lim HW, Metspalu A, Mrowietz U, Mucha S, Rahman P, Reis A, Tejasvi T, Trembath R, Voorhees JJ, Weidinger S, Weichenthal M, Wen X, Eriksson N, Kang HM, Hinds DA, Nair RP, Abecasis GR, Elder JT.

Nat Commun. 2017 May 24;8:15382. doi: 10.1038/ncomms15382.

18.

A vestigial pathway for sex differences in immune regulation.

Liang Y, Kahlenberg JM, Gudjonsson JE.

Cell Mol Immunol. 2017 Jul;14(7):578-580. doi: 10.1038/cmi.2017.28. Epub 2017 May 22. No abstract available.

19.

CD1b-autoreactive T cells contribute to hyperlipidemia-induced skin inflammation in mice.

Bagchi S, He Y, Zhang H, Cao L, Van Rhijn I, Moody DB, Gudjonsson JE, Wang CR.

J Clin Invest. 2017 Jun 1;127(6):2339-2352. doi: 10.1172/JCI92217. Epub 2017 May 2.

20.

GRHL3 binding and enhancers rearrange as epidermal keratinocytes transition between functional states.

Klein RH, Lin Z, Hopkin AS, Gordon W, Tsoi LC, Liang Y, Gudjonsson JE, Andersen B.

PLoS Genet. 2017 Apr 26;13(4):e1006745. doi: 10.1371/journal.pgen.1006745. eCollection 2017 Apr.

21.

The Molecular Revolution in Cutaneous Biology: The Era of Global Transcriptional Analysis.

Johnston A, Sarkar MK, Vrana A, Tsoi LC, Gudjonsson JE.

J Invest Dermatol. 2017 May;137(5):e87-e91. doi: 10.1016/j.jid.2016.02.817. Review.

22.

Imiquimod has strain-dependent effects in mice and does not uniquely model human psoriasis.

Swindell WR, Michaels KA, Sutter AJ, Diaconu D, Fritz Y, Xing X, Sarkar MK, Liang Y, Tsoi A, Gudjonsson JE, Ward NL.

Genome Med. 2017 Mar 9;9(1):24. doi: 10.1186/s13073-017-0415-3.

23.

Endogenous Glucocorticoid Deficiency in Psoriasis Promotes Inflammation and Abnormal Differentiation.

Sarkar MK, Kaplan N, Tsoi LC, Xing X, Liang Y, Swindell WR, Hoover P, Aravind M, Baida G, Clark M, Voorhees JJ, Nair RP, Elder JT, Budunova I, Getsios S, Gudjonsson JE.

J Invest Dermatol. 2017 Jul;137(7):1474-1483. doi: 10.1016/j.jid.2017.02.972. Epub 2017 Mar 1.

24.

IL-1 and IL-36 are dominant cytokines in generalized pustular psoriasis.

Johnston A, Xing X, Wolterink L, Barnes DH, Yin Z, Reingold L, Kahlenberg JM, Harms PW, Gudjonsson JE.

J Allergy Clin Immunol. 2017 Jul;140(1):109-120. doi: 10.1016/j.jaci.2016.08.056. Epub 2016 Dec 31.

25.

A gene network regulated by the transcription factor VGLL3 as a promoter of sex-biased autoimmune diseases.

Liang Y, Tsoi LC, Xing X, Beamer MA, Swindell WR, Sarkar MK, Berthier CC, Stuart PE, Harms PW, Nair RP, Elder JT, Voorhees JJ, Kahlenberg JM, Gudjonsson JE.

Nat Immunol. 2017 Feb;18(2):152-160. doi: 10.1038/ni.3643. Epub 2016 Dec 19.

26.

Induction of Alternative Proinflammatory Cytokines Accounts for Sustained Psoriasiform Skin Inflammation in IL-17C+IL-6KO Mice.

Fritz Y, Klenotic PA, Swindell WR, Yin ZQ, Groft SG, Zhang L, Baliwag J, Camhi MI, Diaconu D, Young AB, Foster AM, Johnston A, Gudjonsson JE, McCormick TS, Ward NL.

J Invest Dermatol. 2017 Mar;137(3):696-705. doi: 10.1016/j.jid.2016.10.021. Epub 2016 Oct 27.

27.

The Snowballing Literature on Imiquimod-Induced Skin Inflammation in Mice: A Critical Appraisal.

Hawkes JE, Gudjonsson JE, Ward NL.

J Invest Dermatol. 2017 Mar;137(3):546-549. doi: 10.1016/j.jid.2016.10.024. Epub 2016 Dec 9.

28.

Interleukin 6 regulates psoriasiform inflammation-associated thrombosis.

Wang Y, Golden JB, Fritz Y, Zhang X, Diaconu D, Camhi MI, Gao H, Dawes SM, Xing X, Ganesh SK, Gudjonsson JE, Simon DI, McCormick TS, Ward NL.

JCI Insight. 2016 Dec 8;1(20):e89384.

29.

MCPIP1/Regnase-1 Restricts IL-17A- and IL-17C-Dependent Skin Inflammation.

Monin L, Gudjonsson JE, Childs EE, Amatya N, Xing X, Verma AH, Coleman BM, Garg AV, Killeen M, Mathers A, Ward NL, Gaffen SL.

J Immunol. 2017 Jan 15;198(2):767-775. doi: 10.4049/jimmunol.1601551. Epub 2016 Dec 5.

30.

Six-transmembrane epithelial antigens of the prostate comprise a novel inflammatory nexus in patients with pustular skin disorders.

Liang Y, Xing X, Beamer MA, Swindell WR, Sarkar MK, Roberts LW, Voorhees JJ, Kahlenberg JM, Harms PW, Johnston A, Gudjonsson JE.

J Allergy Clin Immunol. 2017 Apr;139(4):1217-1227. doi: 10.1016/j.jaci.2016.10.021. Epub 2016 Nov 21.

31.

Patient-reported Outcomes and Clinical Response in Patients with Moderate-to-severe Plaque Psoriasis Treated with Tonsillectomy: A Randomized Controlled Trial.

Thorleifsdottir RH, Sigurdardottir SL, Sigurgeirsson B, Olafsson JH, Sigurdsson MI, Petersen H, Gudjonsson JE, Johnston A, Valdimarsson H.

Acta Derm Venereol. 2017 Mar 10;97(3):340-345. doi: 10.2340/00015555-2562.

32.

Lupus Skin Is Primed for IL-6 Inflammatory Responses through a Keratinocyte-Mediated Autocrine Type I Interferon Loop.

Stannard JN, Reed TJ, Myers E, Lowe L, Sarkar MK, Xing X, Gudjonsson JE, Kahlenberg JM.

J Invest Dermatol. 2017 Jan;137(1):115-122. doi: 10.1016/j.jid.2016.09.008. Epub 2016 Sep 16.

33.

WASP, Tregs, and food allergies - rare disease provides insight into a common problem.

Liang Y, Gudjonsson JE.

J Clin Invest. 2016 Oct 3;126(10):3728-3730. doi: 10.1172/JCI90198. Epub 2016 Sep 19.

34.

HLA-Cw6 homozygosity in plaque psoriasis is associated with streptococcal throat infections and pronounced improvement after tonsillectomy: A prospective case series.

Thorleifsdottir RH, Sigurdardottir SL, Sigurgeirsson B, Olafsson JH, Petersen H, Sigurdsson MI, Gudjonsson JE, Johnston A, Valdimarsson H.

J Am Acad Dermatol. 2016 Nov;75(5):889-896. doi: 10.1016/j.jaad.2016.06.061. Epub 2016 Aug 9.

35.

IL-17 Responses Are the Dominant Inflammatory Signal Linking Inverse, Erythrodermic, and Chronic Plaque Psoriasis.

Xing X, Liang Y, Sarkar MK, Wolterink L, Swindell WR, Voorhees JJ, Harms PW, Kahlenberg JM, Johnston A, Gudjonsson JE.

J Invest Dermatol. 2016 Dec;136(12):2498-2501. doi: 10.1016/j.jid.2016.07.008. Epub 2016 Jul 21. No abstract available.

36.

Sebaceous Gland Atrophy in Psoriasis: An Explanation for Psoriatic Alopecia?

Rittié L, Tejasvi T, Harms PW, Xing X, Nair RP, Gudjonsson JE, Swindell WR, Elder JT.

J Invest Dermatol. 2016 Sep;136(9):1792-800. doi: 10.1016/j.jid.2016.05.113. Epub 2016 Jun 14.

37.

Deficiency of myeloid-related proteins 8 and 14 (Mrp8/Mrp14) does not block inflammaging but prevents steatosis.

Swindell WR, Xing X, Fritz Y, Diaconu D, Simon DI, Ward NL, Gudjonsson JE.

Oncotarget. 2016 Jun 14;7(24):35535-35551. doi: 10.18632/oncotarget.9550.

38.

Cross-Disease Transcriptomics: Unique IL-17A Signaling in Psoriasis Lesions and an Autoimmune PBMC Signature.

Swindell WR, Sarkar MK, Liang Y, Xing X, Gudjonsson JE.

J Invest Dermatol. 2016 Sep;136(9):1820-30. doi: 10.1016/j.jid.2016.04.035. Epub 2016 May 17. Review.

39.

Ongoing Pleuritic Chest Pain and a Guinea Pig: Missed Pulmonary Embolism and Majocchi's Granuloma.

Wargo JJ, Berg A, Gudjonsson JE.

Am J Med. 2016 Sep;129(9):e165-7. doi: 10.1016/j.amjmed.2016.03.029. Epub 2016 Apr 18. No abstract available.

PMID:
27103050
40.

Still waters run deep: latent cytokine activity in nonlesional psoriasis skin.

Johnston A, Yin Z, Gudjonsson JE.

Br J Dermatol. 2016 Jan;174(1):19-20. doi: 10.1111/bjd.14248. No abstract available.

41.

Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture.

Stuart PE, Nair RP, Tsoi LC, Tejasvi T, Das S, Kang HM, Ellinghaus E, Chandran V, Callis-Duffin K, Ike R, Li Y, Wen X, Enerbäck C, Gudjonsson JE, Kõks S, Kingo K, Esko T, Mrowietz U, Reis A, Wichmann HE, Gieger C, Hoffmann P, Nöthen MM, Winkelmann J, Kunz M, Moreta EG, Mease PJ, Ritchlin CT, Bowcock AM, Krueger GG, Lim HW, Weidinger S, Weichenthal M, Voorhees JJ, Rahman P, Gregersen PK, Franke A, Gladman DD, Abecasis GR, Elder JT.

Am J Hum Genet. 2015 Dec 3;97(6):816-36. doi: 10.1016/j.ajhg.2015.10.019. Epub 2015 Nov 28.

42.

CYR61/CCN1: A Novel Mediator of Epidermal Hyperplasia and Inflammation in Psoriasis?

Quan T, Johnston A, Gudjonsson JE, Fisher GJ.

J Invest Dermatol. 2015 Nov;135(11):2562-2564. doi: 10.1038/jid.2015.300.

43.

In Reply.

Coleman KM, Gudjonsson JE, Stecher M.

JAMA Dermatol. 2015 Oct;151(10):1144. doi: 10.1001/jamadermatol.2015.1683. No abstract available.

PMID:
26465767
44.

Proteogenomic analysis of psoriasis reveals discordant and concordant changes in mRNA and protein abundance.

Swindell WR, Remmer HA, Sarkar MK, Xing X, Barnes DH, Wolterink L, Voorhees JJ, Nair RP, Johnston A, Elder JT, Gudjonsson JE.

Genome Med. 2015 Aug 4;7(1):86. doi: 10.1186/s13073-015-0208-5. eCollection 2015.

45.

Dissecting the heterogeneity of skin gene expression patterns in systemic sclerosis.

Assassi S, Swindell WR, Wu M, Tan FD, Khanna D, Furst DE, Tashkin DP, Jahan-Tigh RR, Mayes MD, Gudjonsson JE, Chang JT.

Arthritis Rheumatol. 2015 Nov;67(11):3016-26. doi: 10.1002/art.39289.

46.

Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci.

Tsoi LC, Spain SL, Ellinghaus E, Stuart PE, Capon F, Knight J, Tejasvi T, Kang HM, Allen MH, Lambert S, Stoll SW, Weidinger S, Gudjonsson JE, Koks S, Kingo K, Esko T, Das S, Metspalu A, Weichenthal M, Enerback C, Krueger GG, Voorhees JJ, Chandran V, Rosen CF, Rahman P, Gladman DD, Reis A, Nair RP, Franke A, Barker JN, Abecasis GR, Trembath RC, Elder JT.

Nat Commun. 2015 May 5;6:7001. doi: 10.1038/ncomms8001.

47.

Age-Associated Increase in Skin Fibroblast-Derived Prostaglandin E2 Contributes to Reduced Collagen Levels in Elderly Human Skin.

Li Y, Lei D, Swindell WR, Xia W, Weng S, Fu J, Worthen CA, Okubo T, Johnston A, Gudjonsson JE, Voorhees JJ, Fisher GJ.

J Invest Dermatol. 2015 Sep;135(9):2181-2188. doi: 10.1038/jid.2015.157. Epub 2015 Apr 23.

48.

Psoriasis drug development and GWAS interpretation through in silico analysis of transcription factor binding sites.

Swindell WR, Sarkar MK, Stuart PE, Voorhees JJ, Elder JT, Johnston A, Gudjonsson JE.

Clin Transl Med. 2015 Mar 19;4:13. doi: 10.1186/s40169-015-0054-5. eCollection 2015.

49.

Analysis of long non-coding RNAs highlights tissue-specific expression patterns and epigenetic profiles in normal and psoriatic skin.

Tsoi LC, Iyer MK, Stuart PE, Swindell WR, Gudjonsson JE, Tejasvi T, Sarkar MK, Li B, Ding J, Voorhees JJ, Kang HM, Nair RP, Chinnaiyan AM, Abecasis GR, Elder JT.

Genome Biol. 2015 Jan 30;16:24. doi: 10.1186/s13059-014-0570-4.

50.

Open-Label Trial of MABp1, a True Human Monoclonal Antibody Targeting Interleukin 1α, for the Treatment of Psoriasis.

Coleman KM, Gudjonsson JE, Stecher M.

JAMA Dermatol. 2015 May;151(5):555-6. doi: 10.1001/jamadermatol.2014.5391. No abstract available.

PMID:
25715176

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