Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 155

1.

Transcriptome mining and B cell depletion support a role for B cells in psoriasis pathophysiology.

Toussi A, Merleev A, Barton VR, Le ST, Marusina A, Luxardi G, Kirma J, Xing X, Adamopoulos IE, Fung MA, Raychaudhuri SP, Shimoda M, Gudjonsson JE, Maverakis E.

J Dermatol Sci. 2019 Nov 19. pii: S0923-1811(19)30345-7. doi: 10.1016/j.jdermsci.2019.11.006. [Epub ahead of print] No abstract available.

PMID:
31780313
2.

Application of Machine Learning to Determine Top Predictors of Non-calcified Coronary Burden in Psoriasis: an Observational Cohort Study.

Munger E, Choi H, Dey AK, Elnabawi YA, Groenendyk JW, Rodante J, Keel A, Aksentijevich M, Reddy AS, Khalil N, Argueta-Ameya J, Playford MP, Erb-Alvarez J, Tian X, Wu C, Gudjonsson JE, Tsoi LC, Jafri MS, Sandfort V, Chen MY, Shah SJ, Bluemke DA, Lockshin B, Hasan A, Gelfand JM, Mehta NN.

J Am Acad Dermatol. 2019 Oct 30. pii: S0190-9622(19)32983-4. doi: 10.1016/j.jaad.2019.10.060. [Epub ahead of print]

PMID:
31678339
3.

Psoriasis: Past, Present, and Future.

Billi AC, Gudjonsson JE, Voorhees JJ.

J Invest Dermatol. 2019 Nov;139(11):e133-e142. doi: 10.1016/j.jid.2019.08.437. No abstract available.

PMID:
31648690
4.

IFN-γ enhances cell-mediated cytotoxicity against keratinocytes via JAK2/STAT1 in lichen planus.

Shao S, Tsoi LC, Sarkar MK, Xing X, Xue K, Uppala R, Berthier CC, Zeng C, Patrick M, Billi AC, Fullmer J, Beamer MA, Perez-White B, Getsios S, Schuler A, Voorhees JJ, Choi S, Harms P, Kahlenberg JM, Gudjonsson JE.

Sci Transl Med. 2019 Sep 25;11(511). pii: eaav7561. doi: 10.1126/scitranslmed.aav7561.

PMID:
31554739
5.

Molecular Profiling of Cutaneous Lupus Lesions Identifies Subgroups Distinct from Clinical Phenotypes.

Berthier CC, Tsoi LC, Reed TJ, Stannard JN, Myers EM, Namas R, Xing X, Lazar S, Lowe L, Kretzler M, Gudjonsson JE, Kahlenberg JM.

J Clin Med. 2019 Aug 17;8(8). pii: E1244. doi: 10.3390/jcm8081244.

6.

The Histone Methyltransferase Setdb2 Modulates Macrophage Phenotype and Uric Acid Production in Diabetic Wound Repair.

Kimball AS, Davis FM, denDekker A, Joshi AD, Schaller MA, Bermick J, Xing X, Burant CF, Obi AT, Nysz D, Robinson S, Allen R, Lukacs NW, Henke PK, Gudjonsson JE, Moore BB, Kunkel SL, Gallagher KA.

Immunity. 2019 Aug 20;51(2):258-271.e5. doi: 10.1016/j.immuni.2019.06.015. Epub 2019 Jul 23.

PMID:
31350176
7.

Ultraviolet light induces increased T cell activation in lupus-prone mice via type I IFN-dependent inhibition of T regulatory cells.

Wolf SJ, Estadt SN, Theros J, Moore T, Ellis J, Liu J, Reed TJ, Jacob CO, Gudjonsson JE, Kahlenberg JM.

J Autoimmun. 2019 Sep;103:102291. doi: 10.1016/j.jaut.2019.06.002. Epub 2019 Jun 24.

PMID:
31248690
8.

SIRT3 Regulates Macrophage-Mediated Inflammation in Diabetic Wound Repair.

Boniakowski AM, denDekker AD, Davis FM, Joshi A, Kimball AS, Schaller M, Allen R, Bermick J, Nycz D, Skinner ME, Robinson S, Obi AT, Moore BB, Gudjonsson JE, Lombard D, Kunkel SL, Gallagher KA.

J Invest Dermatol. 2019 Dec;139(12):2528-2537.e2. doi: 10.1016/j.jid.2019.05.017. Epub 2019 Jun 15.

PMID:
31207226
9.

Interleukin-17 receptor D: An orphan receptor finds a home in the skin.

Billi AC, Gudjonsson JE.

Sci Immunol. 2019 Jun 7;4(36). pii: eaax0687. doi: 10.1126/sciimmunol.aax0687. Epub 2019 Jun 7. Review.

PMID:
31175177
10.

Overriding the Immune System's Sweet Tooth: Fatty Acids Rile Up Innate Immunity.

Billi AC, Gudjonsson JE.

Cell. 2019 May 16;177(5):1088-1090. doi: 10.1016/j.cell.2019.04.033.

PMID:
31100264
11.

Integrative Approach to Reveal Cell Type Specificity and Gene Candidates for Psoriatic Arthritis Outside the MHC.

Patrick MT, Stuart PE, Raja K, Chi S, He Z, Voorhees JJ, Tejasvi T, Gudjonsson JE, Kahlenberg JM, Chandran V, Rahman P, Gladman DD, Nair RP, Elder JT, Tsoi LC.

Front Genet. 2019 Apr 11;10:304. doi: 10.3389/fgene.2019.00304. eCollection 2019.

12.

Neutrophil Extracellular Traps Promote Inflammatory Responses in Psoriasis via Activating Epidermal TLR4/IL-36R Crosstalk.

Shao S, Fang H, Dang E, Xue K, Zhang J, Li B, Qiao H, Cao T, Zhuang Y, Shen S, Zhang T, Qiao P, Li C, Gudjonsson JE, Wang G.

Front Immunol. 2019 Apr 5;10:746. doi: 10.3389/fimmu.2019.00746. eCollection 2019.

13.

The female-biased factor VGLL3 drives cutaneous and systemic autoimmunity.

Billi AC, Gharaee-Kermani M, Fullmer J, Tsoi LC, Hill BD, Gruszka D, Ludwig J, Xing X, Estadt S, Wolf SJ, Rizvi SM, Berthier CC, Hodgin JB, Beamer MA, Sarkar MK, Liang Y, Uppala R, Shao S, Zeng C, Harms PW, Verhaegen ME, Voorhees JJ, Wen F, Ward NL, Dlugosz AA, Kahlenberg JM, Gudjonsson JE.

JCI Insight. 2019 Apr 18;4(8). pii: 127291. doi: 10.1172/jci.insight.127291. eCollection 2019 Apr 18.

14.

Neutrophil Subsets, Platelets, and Vascular Disease in Psoriasis.

Teague HL, Varghese NJ, Tsoi LC, Dey AK, Garshick MS, Silverman JI, Baumer Y, Harrington CL, Stempinski E, Elnabawi YA, Dagur PK, Cui K, Tunc I, Seifuddin F, Joshi AA, Stansky E, Purmalek MM, Rodante JA, Keel A, Aridi TZ, Carmona-Rivera C, Sanda GE, Chen MY, Pirooznia M, McCoy JP Jr, Gelfand JM, Zhao K, Gudjonsson JE, Playford MP, Kaplan MJ, Berger JS, Mehta NN.

JACC Basic Transl Sci. 2019 Feb 25;4(1):1-14. doi: 10.1016/j.jacbts.2018.10.008. eCollection 2019 Feb.

15.

Making New Connections-Chromosome Conformation Capture for Identification of Disease-Associated Target Genes.

Patrick MT, Tsoi LC, Gudjonsson JE.

J Invest Dermatol. 2019 Mar;139(3):514-517. doi: 10.1016/j.jid.2018.11.026.

PMID:
30797317
16.

Hypersensitive IFN Responses in Lupus Keratinocytes Reveal Key Mechanistic Determinants in Cutaneous Lupus.

Tsoi LC, Hile GA, Berthier CC, Sarkar MK, Reed TJ, Liu J, Uppala R, Patrick M, Raja K, Xing X, Xing E, He K, Gudjonsson JE, Kahlenberg JM.

J Immunol. 2019 Apr 1;202(7):2121-2130. doi: 10.4049/jimmunol.1800650. Epub 2019 Feb 11.

PMID:
30745462
17.

Atopic Dermatitis Is an IL-13-Dominant Disease with Greater Molecular Heterogeneity Compared to Psoriasis.

Tsoi LC, Rodriguez E, Degenhardt F, Baurecht H, Wehkamp U, Volks N, Szymczak S, Swindell WR, Sarkar MK, Raja K, Shao S, Patrick M, Gao Y, Uppala R, Perez White BE, Getsios S, Harms PW, Maverakis E, Elder JT, Franke A, Gudjonsson JE, Weidinger S.

J Invest Dermatol. 2019 Jul;139(7):1480-1489. doi: 10.1016/j.jid.2018.12.018. Epub 2019 Jan 11.

PMID:
30641038
18.

Adalimumab in Psoriasis: How Much Is Enough?

Billi AC, Gudjonsson JE.

J Invest Dermatol. 2019 Jan;139(1):19-22. doi: 10.1016/j.jid.2018.08.012.

PMID:
30579425
19.

Clinical Goals and Barriers to Effective Psoriasis Care.

Strober BE, van der Walt JM, Armstrong AW, Bourcier M, Carvalho AVE, Chouela E, Cohen AD, de la Cruz C, Ellis CN, Finlay AY, Gottlieb AB, Gudjonsson JE, Iversen L, Kleyn CE, Leonardi CL, Lynde CW, Ryan C, Theng CT, Valenzuela F, Vender R, Wu JJ, Young HS, Kimball AB.

Dermatol Ther (Heidelb). 2019 Mar;9(1):5-18. doi: 10.1007/s13555-018-0279-5. Epub 2018 Dec 21.

20.

The influence of interferon on healthy and diseased skin.

Hile GA, Gudjonsson JE, Kahlenberg JM.

Cytokine. 2018 Dec 6. pii: S1043-4666(18)30440-X. doi: 10.1016/j.cyto.2018.11.022. [Epub ahead of print]

PMID:
30527631
21.

Novel cytokine and chemokine markers of hidradenitis suppurativa reflect chronic inflammation and itch.

Vossen ARJV, van der Zee HH, Tsoi LC, Xing X, Devalaraja M, Gudjonsson JE, Prens EP.

Allergy. 2019 Mar;74(3):631-634. doi: 10.1111/all.13665. Epub 2018 Dec 10. No abstract available.

22.

Human and Murine Evidence for Mechanisms Driving Autoimmune Photosensitivity.

Wolf SJ, Estadt SN, Gudjonsson JE, Kahlenberg JM.

Front Immunol. 2018 Oct 23;9:2430. doi: 10.3389/fimmu.2018.02430. eCollection 2018. Review.

23.

Sex bias in autoimmunity.

Billi AC, Kahlenberg JM, Gudjonsson JE.

Curr Opin Rheumatol. 2019 Jan;31(1):53-61. doi: 10.1097/BOR.0000000000000564.

PMID:
30394940
24.

Drug Repurposing Prediction for Immune-Mediated Cutaneous Diseases using a Word-Embedding-Based Machine Learning Approach.

Patrick MT, Raja K, Miller K, Sotzen J, Gudjonsson JE, Elder JT, Tsoi LC.

J Invest Dermatol. 2019 Mar;139(3):683-691. doi: 10.1016/j.jid.2018.09.018. Epub 2018 Oct 17.

25.

Genetic signature to provide robust risk assessment of psoriatic arthritis development in psoriasis patients.

Patrick MT, Stuart PE, Raja K, Gudjonsson JE, Tejasvi T, Yang J, Chandran V, Das S, Callis-Duffin K, Ellinghaus E, Enerbäck C, Esko T, Franke A, Kang HM, Krueger GG, Lim HW, Rahman P, Rosen CF, Weidinger S, Weichenthal M, Wen X, Voorhees JJ, Abecasis GR, Gladman DD, Nair RP, Elder JT, Tsoi LC.

Nat Commun. 2018 Oct 9;9(1):4178. doi: 10.1038/s41467-018-06672-6.

26.

IL-17 integrates multiple self-reinforcing, feed-forward mechanisms through the RNA binding protein Arid5a.

Amatya N, Childs EE, Cruz JA, Aggor FEY, Garg AV, Berman AJ, Gudjonsson JE, Atasoy U, Gaffen SL.

Sci Signal. 2018 Oct 9;11(551). pii: eaat4617. doi: 10.1126/scisignal.aat4617.

27.

Advances in Cutaneous Lupus Erythematosus and Dermatomyositis: A Report from the 4th International Conference on Cutaneous Lupus Erythematosus-An Ongoing Need for International Consensus and Collaborations.

Concha JSS, Patsatsi A, Marshak-Rothstein A, Liu ML, Sinha AA, Lee LA, Merola JF, Jabbari A, Gudjonsson JE, Chasset F, Jarrett P, Chong B, Arkin L, Fernandez AP, Caproni M, Greenberg SA, Kim HJ, Pearson DR, Femia A, Vleugels RA, Fiorentino D, Fujimoto M, Wenzel J, Werth VP.

J Invest Dermatol. 2019 Feb;139(2):270-276. doi: 10.1016/j.jid.2018.08.017. Epub 2018 Sep 19. No abstract available.

PMID:
30243657
28.

Photosensitivity and type I IFN responses in cutaneous lupus are driven by epidermal-derived interferon kappa.

Sarkar MK, Hile GA, Tsoi LC, Xing X, Liu J, Liang Y, Berthier CC, Swindell WR, Patrick MT, Shao S, Tsou PS, Uppala R, Beamer MA, Srivastava A, Bielas SL, Harms PW, Getsios S, Elder JT, Voorhees JJ, Gudjonsson JE, Kahlenberg JM.

Ann Rheum Dis. 2018 Nov;77(11):1653-1664. doi: 10.1136/annrheumdis-2018-213197. Epub 2018 Jul 18.

29.

Meta-analysis of RNA sequencing datasets reveals an association between TRAJ23, psoriasis, and IL-17A.

Merleev AA, Marusina AI, Ma C, Elder JT, Tsoi LC, Raychaudhuri SP, Weidinger S, Wang EA, Adamopoulos IE, Luxardi G, Gudjonsson JE, Shimoda M, Maverakis E.

JCI Insight. 2018 Jul 12;3(13). pii: 120682. doi: 10.1172/jci.insight.120682.

30.

Dietary Recommendations for Adults With Psoriasis or Psoriatic Arthritis From the Medical Board of the National Psoriasis Foundation: A Systematic Review.

Ford AR, Siegel M, Bagel J, Cordoro KM, Garg A, Gottlieb A, Green LJ, Gudjonsson JE, Koo J, Lebwohl M, Liao W, Mandelin AM 2nd, Markenson JA, Mehta N, Merola JF, Prussick R, Ryan C, Schwartzman S, Siegel EL, Van Voorhees AS, Wu JJ, Armstrong AW.

JAMA Dermatol. 2018 Aug 1;154(8):934-950. doi: 10.1001/jamadermatol.2018.1412.

PMID:
29926091
31.

Dystrophic calcifications point the way-Unusual and early diagnostic clue of Conradi-Hünermann-Happle syndrome.

Yu K, Reid AT, Chen SJT, Patel RM, Donn SM, Gudjonsson JE, Lowe L.

JAAD Case Rep. 2018 Mar 31;4(4):333-336. doi: 10.1016/j.jdcr.2017.10.018. eCollection 2018 May. No abstract available.

32.

RNA-Seq Analysis of IL-1B and IL-36 Responses in Epidermal Keratinocytes Identifies a Shared MyD88-Dependent Gene Signature.

Swindell WR, Beamer MA, Sarkar MK, Loftus S, Fullmer J, Xing X, Ward NL, Tsoi LC, Kahlenberg MJ, Liang Y, Gudjonsson JE.

Front Immunol. 2018 Jan 29;9:80. doi: 10.3389/fimmu.2018.00080. eCollection 2018.

33.

RNA-seq identifies a diminished differentiation gene signature in primary monolayer keratinocytes grown from lesional and uninvolved psoriatic skin.

Swindell WR, Sarkar MK, Liang Y, Xing X, Baliwag J, Elder JT, Johnston A, Ward NL, Gudjonsson JE.

Sci Rep. 2017 Dec 22;7(1):18045. doi: 10.1038/s41598-017-18404-9.

34.

Research Techniques Made Simple: Murine Models of Human Psoriasis.

Hawkes JE, Adalsteinsson JA, Gudjonsson JE, Ward NL.

J Invest Dermatol. 2018 Jan;138(1):e1-e8. doi: 10.1016/j.jid.2017.10.013. Review.

35.

Unsuspected lymphomatoid granulomatosis in a patient with antisynthetase syndrome.

Skala SL, Hristov AC, Gudjonsson JE, Chan MP.

Cutis. 2017 Oct;100(4):E22-E26.

PMID:
29136066
36.

IFN-γ and TNF-α synergism may provide a link between psoriasis and inflammatory atherogenesis.

Mehta NN, Teague HL, Swindell WR, Baumer Y, Ward NL, Xing X, Baugous B, Johnston A, Joshi AA, Silverman J, Barnes DH, Wolterink L, Nair RP, Stuart PE, Playford M, Voorhees JJ, Sarkar MK, Elder JT, Gallagher K, Ganesh SK, Gudjonsson JE.

Sci Rep. 2017 Oct 23;7(1):13831. doi: 10.1038/s41598-017-14365-1.

37.

Transcriptional determinants of individualized inflammatory responses at anatomically separate sites.

Tsoi LC, Yang J, Liang Y, Sarkar MK, Xing X, Beamer MA, Aphale A, Raja K, Kozlow JH, Getsios S, Voorhees JJ, Kahlenberg JM, Elder JT, Gudjonsson JE.

J Allergy Clin Immunol. 2018 Feb;141(2):805-808. doi: 10.1016/j.jaci.2017.07.054. Epub 2017 Oct 13. No abstract available.

38.

Exome-wide association study reveals novel psoriasis susceptibility locus at TNFSF15 and rare protective alleles in genes contributing to type I IFN signalling.

Dand N, Mucha S, Tsoi LC, Mahil SK, Stuart PE, Arnold A, Baurecht H, Burden AD, Callis Duffin K, Chandran V, Curtis CJ, Das S, Ellinghaus D, Ellinghaus E, Enerback C, Esko T, Gladman DD, Griffiths CEM, Gudjonsson JE, Hoffman P, Homuth G, Hüffmeier U, Krueger GG, Laudes M, Lee SH, Lieb W, Lim HW, Löhr S, Mrowietz U, Müller-Nurayid M, Nöthen M, Peters A, Rahman P, Reis A, Reynolds NJ, Rodriguez E, Schmidt CO, Spain SL, Strauch K, Tejasvi T, Voorhees JJ, Warren RB, Weichenthal M, Weidinger S, Zawistowski M, Nair RP, Capon F, Smith CH, Trembath RC, Abecasis GR, Elder JT, Franke A, Simpson MA, Barker JN.

Hum Mol Genet. 2017 Nov 1;26(21):4301-4313. doi: 10.1093/hmg/ddx328.

39.

Scleroderma keratinocytes promote fibroblast activation independent of transforming growth factor beta.

McCoy SS, Reed TJ, Berthier CC, Tsou PS, Liu J, Gudjonsson JE, Khanna D, Kahlenberg JM.

Rheumatology (Oxford). 2017 Nov 1;56(11):1970-1981. doi: 10.1093/rheumatology/kex280.

40.

Psoriasis: a mixed autoimmune and autoinflammatory disease.

Liang Y, Sarkar MK, Tsoi LC, Gudjonsson JE.

Curr Opin Immunol. 2017 Dec;49:1-8. doi: 10.1016/j.coi.2017.07.007. Epub 2017 Jul 22. Review.

41.

Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants.

Tsoi LC, Stuart PE, Tian C, Gudjonsson JE, Das S, Zawistowski M, Ellinghaus E, Barker JN, Chandran V, Dand N, Duffin KC, Enerbäck C, Esko T, Franke A, Gladman DD, Hoffmann P, Kingo K, Kõks S, Krueger GG, Lim HW, Metspalu A, Mrowietz U, Mucha S, Rahman P, Reis A, Tejasvi T, Trembath R, Voorhees JJ, Weidinger S, Weichenthal M, Wen X, Eriksson N, Kang HM, Hinds DA, Nair RP, Abecasis GR, Elder JT.

Nat Commun. 2017 May 24;8:15382. doi: 10.1038/ncomms15382.

42.

A vestigial pathway for sex differences in immune regulation.

Liang Y, Kahlenberg JM, Gudjonsson JE.

Cell Mol Immunol. 2017 Jul;14(7):578-580. doi: 10.1038/cmi.2017.28. Epub 2017 May 22. No abstract available.

43.

CD1b-autoreactive T cells contribute to hyperlipidemia-induced skin inflammation in mice.

Bagchi S, He Y, Zhang H, Cao L, Van Rhijn I, Moody DB, Gudjonsson JE, Wang CR.

J Clin Invest. 2017 Jun 1;127(6):2339-2352. doi: 10.1172/JCI92217. Epub 2017 May 2.

44.

GRHL3 binding and enhancers rearrange as epidermal keratinocytes transition between functional states.

Klein RH, Lin Z, Hopkin AS, Gordon W, Tsoi LC, Liang Y, Gudjonsson JE, Andersen B.

PLoS Genet. 2017 Apr 26;13(4):e1006745. doi: 10.1371/journal.pgen.1006745. eCollection 2017 Apr.

45.

The Molecular Revolution in Cutaneous Biology: The Era of Global Transcriptional Analysis.

Johnston A, Sarkar MK, Vrana A, Tsoi LC, Gudjonsson JE.

J Invest Dermatol. 2017 May;137(5):e87-e91. doi: 10.1016/j.jid.2016.02.817. Review.

46.

Imiquimod has strain-dependent effects in mice and does not uniquely model human psoriasis.

Swindell WR, Michaels KA, Sutter AJ, Diaconu D, Fritz Y, Xing X, Sarkar MK, Liang Y, Tsoi A, Gudjonsson JE, Ward NL.

Genome Med. 2017 Mar 9;9(1):24. doi: 10.1186/s13073-017-0415-3.

47.

Endogenous Glucocorticoid Deficiency in Psoriasis Promotes Inflammation and Abnormal Differentiation.

Sarkar MK, Kaplan N, Tsoi LC, Xing X, Liang Y, Swindell WR, Hoover P, Aravind M, Baida G, Clark M, Voorhees JJ, Nair RP, Elder JT, Budunova I, Getsios S, Gudjonsson JE.

J Invest Dermatol. 2017 Jul;137(7):1474-1483. doi: 10.1016/j.jid.2017.02.972. Epub 2017 Mar 1. Erratum in: J Invest Dermatol. 2017 Dec;137(12):2665.

48.

IL-1 and IL-36 are dominant cytokines in generalized pustular psoriasis.

Johnston A, Xing X, Wolterink L, Barnes DH, Yin Z, Reingold L, Kahlenberg JM, Harms PW, Gudjonsson JE.

J Allergy Clin Immunol. 2017 Jul;140(1):109-120. doi: 10.1016/j.jaci.2016.08.056. Epub 2016 Dec 31.

49.

A gene network regulated by the transcription factor VGLL3 as a promoter of sex-biased autoimmune diseases.

Liang Y, Tsoi LC, Xing X, Beamer MA, Swindell WR, Sarkar MK, Berthier CC, Stuart PE, Harms PW, Nair RP, Elder JT, Voorhees JJ, Kahlenberg JM, Gudjonsson JE.

Nat Immunol. 2017 Feb;18(2):152-160. doi: 10.1038/ni.3643. Epub 2016 Dec 19.

50.

Induction of Alternative Proinflammatory Cytokines Accounts for Sustained Psoriasiform Skin Inflammation in IL-17C+IL-6KO Mice.

Fritz Y, Klenotic PA, Swindell WR, Yin ZQ, Groft SG, Zhang L, Baliwag J, Camhi MI, Diaconu D, Young AB, Foster AM, Johnston A, Gudjonsson JE, McCormick TS, Ward NL.

J Invest Dermatol. 2017 Mar;137(3):696-705. doi: 10.1016/j.jid.2016.10.021. Epub 2016 Oct 27.

Supplemental Content

Loading ...
Support Center