Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 254

1.

Agonist-mediated switching of ion selectivity in TPC2 differentially promotes lysosomal function.

Gerndt S, Chen CC, Chao YK, Yuan Y, Burgstaller S, Scotto Rosato A, Krogsaeter E, Urban N, Jacob K, Nguyen ONP, Miller MT, Keller M, Vollmar AM, Gudermann T, Zierler S, Schredelseker J, Schaefer M, Biel M, Malli R, Wahl-Schott C, Bracher F, Patel S, Grimm C.

Elife. 2020 Mar 16;9. pii: e54712. doi: 10.7554/eLife.54712.

2.

Shape Similarity by Fractal Dimensionality: An Application in the de novo Design of (-)-Englerin A Mimetics.

Friedrich L, Byrne R, Treder A, Singh I, Bauer C, Gudermann T, Mederos Y Schnitzler M, Storch U, Schneider G.

ChemMedChem. 2020 Apr 3;15(7):566-570. doi: 10.1002/cmdc.202000017. Epub 2020 Mar 12.

PMID:
32162837
3.

Assessment of the Acute Inhalation Toxicity of Airborne Particles by Exposing Cultivated Human Lung Cells at the Air-Liquid Interface.

Tsoutsoulopoulos A, Gohlsch K, Möhle N, Breit A, Hoffmann S, Krischenowski O, Mückter H, Gudermann T, Thiermann H, Aufderheide M, Steinritz D.

J Vis Exp. 2020 Feb 23;(156). doi: 10.3791/60572.

PMID:
32150152
4.

The antiarrhythmic compound efsevin directly modulates voltage-dependent anion channel 2 by binding to its inner wall and enhancing mitochondrial Ca2+ uptake.

Wilting F, Kopp R, Gurnev PA, Schedel A, Dupper NJ, Kwon O, Nicke A, Gudermann T, Schredelseker J.

Br J Pharmacol. 2020 Feb 14. doi: 10.1111/bph.15022. [Epub ahead of print]

PMID:
32059260
5.

Expression of Taste Receptor 2 Subtypes in Human Testis and Sperm.

Governini L, Semplici B, Pavone V, Crifasi L, Marrocco C, De Leo V, Arlt E, Gudermann T, Boekhoff I, Luddi A, Piomboni P.

J Clin Med. 2020 Jan 18;9(1). pii: E264. doi: 10.3390/jcm9010264.

6.

Helix 8 is the essential structural motif of mechanosensitive GPCRs.

Erdogmus S, Storch U, Danner L, Becker J, Winter M, Ziegler N, Wirth A, Offermanns S, Hoffmann C, Gudermann T, Mederos Y Schnitzler M.

Nat Commun. 2019 Dec 19;10(1):5784. doi: 10.1038/s41467-019-13722-0.

7.

Inhibition of TRPM7 blocks MRTF/SRF-dependent transcriptional and tumorigenic activity.

Voringer S, Schreyer L, Nadolni W, Meier MA, Woerther K, Mittermeier C, Ferioli S, Singer S, Holzer K, Zierler S, Chubanov V, Liebl B, Gudermann T, Muehlich S.

Oncogene. 2020 Mar;39(11):2328-2344. doi: 10.1038/s41388-019-1140-8. Epub 2019 Dec 16.

PMID:
31844251
8.

Exposure of 19 substances to lung A549 cells at the air liquid interface or under submerged conditions reveals high correlation between cytotoxicity in vitro and CLP classifications for acute lung toxicity.

Gohlsch K, Mückter H, Steinritz D, Aufderheide M, Hoffmann S, Gudermann T, Breit A.

Toxicol Lett. 2019 Nov;316:119-126. doi: 10.1016/j.toxlet.2019.09.014. Epub 2019 Sep 17.

PMID:
31539570
9.

Sulfur mustard alkylates steroid hormones and impacts hormone function in vitro.

Lüling R, Singer H, Popp T, John H, Boekhoff I, Thiermann H, Daumann LJ, Karaghiosoff K, Gudermann T, Steinritz D.

Arch Toxicol. 2019 Nov;93(11):3141-3152. doi: 10.1007/s00204-019-02571-x. Epub 2019 Sep 12.

PMID:
31515601
10.

Skin sensitizing effects of sulfur mustard and other alkylating agents in accordance to OECD guidelines.

Steinritz D, Lang S, Popp T, Siegert M, Rothmiller S, Kranawetvogl A, Schmidt A, John H, Gudermann T, Thiermann H, Kehe K.

Toxicol Lett. 2019 Oct 10;314:172-180. doi: 10.1016/j.toxlet.2019.07.023. Epub 2019 Aug 9.

PMID:
31404593
11.

Small Fluorescein Arsenical Hairpin-Based Förster Resonance Energy Transfer Analysis Reveals Changes in Amino- to Carboxyl-Terminal Interactions upon OAG Activation of Classical Transient Receptor Potential 6.

Fiedler S, Storch U, Erdogmus S, Gudermann T, Mederos Y Schnitzler M, Dietrich A.

Mol Pharmacol. 2019 Jul;96(1):90-98. doi: 10.1124/mol.119.115949.

PMID:
31171574
12.

Validation of the CULTEX® Radial Flow System for the assessment of the acute inhalation toxicity of airborne particles.

Tsoutsoulopoulos A, Gohlsch K, Möhle N, Breit A, Hoffmann S, Krischenowski O, Mückter H, Gudermann T, Thiermann H, Aufderheide M, Steinritz D.

Toxicol In Vitro. 2019 Aug;58:245-255. doi: 10.1016/j.tiv.2019.03.020. Epub 2019 Mar 16.

PMID:
30890356
13.

Taste Receptors: New Players in Sperm Biology.

Luddi A, Governini L, Wilmskötter D, Gudermann T, Boekhoff I, Piomboni P.

Int J Mol Sci. 2019 Feb 22;20(4). pii: E967. doi: 10.3390/ijms20040967. Review.

14.

TRPM7 is the central gatekeeper of intestinal mineral absorption essential for postnatal survival.

Mittermeier L, Demirkhanyan L, Stadlbauer B, Breit A, Recordati C, Hilgendorff A, Matsushita M, Braun A, Simmons DG, Zakharian E, Gudermann T, Chubanov V.

Proc Natl Acad Sci U S A. 2019 Mar 5;116(10):4706-4715. doi: 10.1073/pnas.1810633116. Epub 2019 Feb 15.

15.

A novel exposure system generating nebulized aerosol of sulfur mustard in comparison to the standard submerse exposure.

Tsoutsoulopoulos A, Siegert M, John H, Zubel T, Mangerich A, Schmidt A, Mückter H, Gudermann T, Thiermann H, Steinritz D, Popp T.

Chem Biol Interact. 2019 Jan 25;298:121-128. doi: 10.1016/j.cbi.2018.11.025. Epub 2018 Nov 28.

PMID:
30502332
16.

TRPM7 reflected in Cryo-EMirror.

Chubanov V, Mittermeier L, Gudermann T.

Cell Calcium. 2018 Dec;76:129-131. doi: 10.1016/j.ceca.2018.11.004. Epub 2018 Nov 15.

PMID:
30470536
17.

Emerging Roles of Diacylglycerol-Sensitive TRPC4/5 Channels.

Mederos Y Schnitzler M, Gudermann T, Storch U.

Cells. 2018 Nov 20;7(11). pii: E218. doi: 10.3390/cells7110218. Review.

18.

Necrosulfonamide - Unexpected effect in the course of a sulfur mustard intoxication.

Menacher G, Balszuweit F, Lang S, Thiermann H, Kehe K, Gudermann T, Schmidt A, Steinritz D, Popp T.

Chem Biol Interact. 2019 Jan 25;298:80-85. doi: 10.1016/j.cbi.2018.10.030. Epub 2018 Nov 2.

PMID:
30391637
19.

Insulin-like growth factor-1 acts as a zeitgeber on hypothalamic circadian clock gene expression via glycogen synthase kinase-3β signaling.

Breit A, Miek L, Schredelseker J, Geibel M, Merrow M, Gudermann T.

J Biol Chem. 2018 Nov 2;293(44):17278-17290. doi: 10.1074/jbc.RA118.004429. Epub 2018 Sep 14.

20.

Transient Receptor Potential Channel A1 (TRPA1) Regulates Sulfur Mustard-Induced Expression of Heat Shock 70 kDa Protein 6 (HSPA6) In Vitro.

Lüling R, John H, Gudermann T, Thiermann H, Mückter H, Popp T, Steinritz D.

Cells. 2018 Aug 31;7(9). pii: E126. doi: 10.3390/cells7090126.

21.

Sarcopenia - Endocrinological and Neurological Aspects.

Stangl MK, Böcker W, Chubanov V, Ferrari U, Fischereder M, Gudermann T, Hesse E, Meinke P, Reincke M, Reisch N, Saller MM, Seissler J, Schmidmaier R, Schoser B, Then C, Thorand B, Drey M.

Exp Clin Endocrinol Diabetes. 2019 Jan;127(1):8-22. doi: 10.1055/a-0672-1007. Epub 2018 Sep 10. Review.

PMID:
30199918
22.

TRPs in Tox: Involvement of Transient Receptor Potential-Channels in Chemical-Induced Organ Toxicity-A Structured Review.

Steinritz D, Stenger B, Dietrich A, Gudermann T, Popp T.

Cells. 2018 Aug 7;7(8). pii: E98. doi: 10.3390/cells7080098. Review.

23.

An incretin-based tri-agonist promotes superior insulin secretion from murine pancreatic islets via PLC activation.

Khajavi N, Finan B, Kluth O, Müller TD, Mergler S, Schulz A, Kleinau G, Scheerer P, Schürmann A, Gudermann T, Tschöp MH, Krude H, DiMarchi RD, Biebermann H.

Cell Signal. 2018 Nov;51:13-22. doi: 10.1016/j.cellsig.2018.07.006. Epub 2018 Jul 25.

PMID:
30055232
24.

Hypoxic pulmonary vasoconstriction in isolated mouse pulmonary arterial vessels.

Strielkov I, Krause NC, Sommer N, Schermuly RT, Ghofrani HA, Grimminger F, Gudermann T, Dietrich A, Weissmann N.

Exp Physiol. 2018 Sep;103(9):1185-1191. doi: 10.1113/EP087117. Epub 2018 Jul 6.

PMID:
29917290
25.

TRPA1 channels: expression in non-neuronal murine lung tissues and dispensability for hyperoxia-induced alveolar epithelial hyperplasia.

Kannler M, Lüling R, Yildirim AÖ, Gudermann T, Steinritz D, Dietrich A.

Pflugers Arch. 2018 Aug;470(8):1231-1241. doi: 10.1007/s00424-018-2148-6. Epub 2018 May 12.

PMID:
29754249
26.

Cutting Edge: Imbalanced Cation Homeostasis in MAGT1-Deficient B Cells Dysregulates B Cell Development and Signaling in Mice.

Gotru SK, Gil-Pulido J, Beyersdorf N, Diefenbach A, Becker IC, Vögtle T, Remer K, Chubanov V, Gudermann T, Hermanns HM, Nieswandt B, Kerkau T, Zernecke A, Braun A.

J Immunol. 2018 Apr 15;200(8):2529-2534. doi: 10.4049/jimmunol.1701467. Epub 2018 Mar 26.

27.

Renal Functions of TRP Channels in Health and Disease.

Chubanov V, Kubanek S, Fiedler S, Mittermeier L, Gudermann T, Dietrich A.

In: Emir TLR, editor. Neurobiology of TRP Channels. 2nd edition. Boca Raton (FL): CRC Press/Taylor & Francis; 2017. Chapter 10.

28.

Suppression of Arrhythmia by Enhancing Mitochondrial Ca2+ Uptake in Catecholaminergic Ventricular Tachycardia Models.

Schweitzer MK, Wilting F, Sedej S, Dreizehnter L, Dupper NJ, Tian Q, Moretti A, My I, Kwon O, Priori SG, Laugwitz KL, Storch U, Lipp P, Breit A, Mederos Y Schnitzler M, Gudermann T, Schredelseker J.

JACC Basic Transl Sci. 2017 Dec;2(6):737-747. doi: 10.1016/j.jacbts.2017.06.008. Epub 2017 Nov 8.

29.

PhoDAGs Enable Optical Control of Diacylglycerol-Sensitive Transient Receptor Potential Channels.

Leinders-Zufall T, Storch U, Bleymehl K, Mederos Y Schnitzler M, Frank JA, Konrad DB, Trauner D, Gudermann T, Zufall F.

Cell Chem Biol. 2018 Feb 15;25(2):215-223.e3. doi: 10.1016/j.chembiol.2017.11.008. Epub 2017 Dec 21.

30.

TRPM7 kinase activity is essential for T cell colonization and alloreactivity in the gut.

Romagnani A, Vettore V, Rezzonico-Jost T, Hampe S, Rottoli E, Nadolni W, Perotti M, Meier MA, Hermanns C, Geiger S, Wennemuth G, Recordati C, Matsushita M, Muehlich S, Proietti M, Chubanov V, Gudermann T, Grassi F, Zierler S.

Nat Commun. 2017 Dec 4;8(1):1917. doi: 10.1038/s41467-017-01960-z.

31.

Migrating Platelets Are Mechano-scavengers that Collect and Bundle Bacteria.

Gaertner F, Ahmad Z, Rosenberger G, Fan S, Nicolai L, Busch B, Yavuz G, Luckner M, Ishikawa-Ankerhold H, Hennel R, Benechet A, Lorenz M, Chandraratne S, Schubert I, Helmer S, Striednig B, Stark K, Janko M, Böttcher RT, Verschoor A, Leon C, Gachet C, Gudermann T, Mederos Y Schnitzler M, Pincus Z, Iannacone M, Haas R, Wanner G, Lauber K, Sixt M, Massberg S.

Cell. 2017 Nov 30;171(6):1368-1382.e23. doi: 10.1016/j.cell.2017.11.001.

32.

Sulfur mustard-induced epigenetic modifications over time - a pilot study.

Simons T, Steinritz D, Bölck B, Schmidt A, Popp T, Thiermann H, Gudermann T, Bloch W, Kehe K.

Toxicol Lett. 2018 Sep 1;293:45-50. doi: 10.1016/j.toxlet.2017.11.010. Epub 2017 Nov 16.

PMID:
29155286
33.

TRPM7 Kinase Controls Calcium Responses in Arterial Thrombosis and Stroke in Mice.

Gotru SK, Chen W, Kraft P, Becker IC, Wolf K, Stritt S, Zierler S, Hermanns HM, Rao D, Perraud AL, Schmitz C, Zahedi RP, Noy PJ, Tomlinson MG, Dandekar T, Matsushita M, Chubanov V, Gudermann T, Stoll G, Nieswandt B, Braun A.

Arterioscler Thromb Vasc Biol. 2018 Feb;38(2):344-352. doi: 10.1161/ATVBAHA.117.310391. Epub 2017 Nov 16.

PMID:
29146750
34.

Role of kinase-coupled TRP channels in mineral homeostasis.

Chubanov V, Mittermeier L, Gudermann T.

Pharmacol Ther. 2018 Apr;184:159-176. doi: 10.1016/j.pharmthera.2017.11.003. Epub 2017 Nov 9. Review.

35.

Lung Ischaemia-Reperfusion Injury: The Role of Reactive Oxygen Species.

Pak O, Sydykov A, Kosanovic D, Schermuly RT, Dietrich A, Schröder K, Brandes RP, Gudermann T, Sommer N, Weissmann N.

Adv Exp Med Biol. 2017;967:195-225. doi: 10.1007/978-3-319-63245-2_12. Review.

PMID:
29047088
36.

Cell calcium special issue: Preface.

Gudermann T, Flockerzi V.

Cell Calcium. 2017 Nov;67:21. doi: 10.1016/j.ceca.2017.08.001. Epub 2017 Aug 2. No abstract available.

PMID:
29029786
37.

Immediate responses of the cockroach Blaptica dubia after the exposure to sulfur mustard.

Popp T, Lüling R, Boekhoff I, Seeger T, Branoner F, Gudermann T, Thiermann H, Worek F, Steinritz D.

Arch Toxicol. 2018 Jan;92(1):337-346. doi: 10.1007/s00204-017-2064-0. Epub 2017 Sep 20.

PMID:
28932886
38.

Zinc chloride-induced TRPA1 activation does not contribute to toxicity in vitro.

Steinritz D, Zehfuß F, Stenger B, Schmidt A, Popp T, Kehe K, Mückter H, Thiermann H, Gudermann T.

Toxicol Lett. 2018 Sep 1;293:133-139. doi: 10.1016/j.toxlet.2017.09.008. Epub 2017 Sep 14.

PMID:
28919489
39.

Anti-apoptotic and moderate anti-inflammatory effects of berberine in sulfur mustard exposed keratinocytes.

Lang S, Popp T, Kriegs CS, Schmidt A, Balszuweit F, Menacher G, Kehe K, Thiermann H, Gudermann T, Steinritz D.

Toxicol Lett. 2018 Sep 1;293:2-8. doi: 10.1016/j.toxlet.2017.09.004. Epub 2017 Sep 13.

PMID:
28916288
40.

Effects of anti-inflammatory compounds on sulfur mustard injured cells: Recommendations and caveats suggested by in vitro cell culture models.

Menacher G, Steinritz D, Schmidt A, Popp T, Worek F, Gudermann T, Thiermann H, Balszuweit F.

Toxicol Lett. 2018 Sep 1;293:91-97. doi: 10.1016/j.toxlet.2017.09.003. Epub 2017 Sep 12.

PMID:
28916287
41.

TRPM6 and TRPM7 differentially contribute to the relief of heteromeric TRPM6/7 channels from inhibition by cytosolic Mg2+ and Mg·ATP.

Ferioli S, Zierler S, Zaißerer J, Schredelseker J, Gudermann T, Chubanov V.

Sci Rep. 2017 Aug 18;7(1):8806. doi: 10.1038/s41598-017-08144-1.

42.

The Role of Transient Receptor Potential Channel 6 Channels in the Pulmonary Vasculature.

Malczyk M, Erb A, Veith C, Ghofrani HA, Schermuly RT, Gudermann T, Dietrich A, Weissmann N, Sydykov A.

Front Immunol. 2017 Jun 16;8:707. doi: 10.3389/fimmu.2017.00707. eCollection 2017. Review.

43.

Transient receptor potential (TRP) channels as molecular targets in lung toxicology and associated diseases.

Dietrich A, Steinritz D, Gudermann T.

Cell Calcium. 2017 Nov;67:123-137. doi: 10.1016/j.ceca.2017.04.005. Epub 2017 Apr 26. Review.

PMID:
28499580
44.

Erratum to: Dynamic monitoring of Gi/o-protein-mediated decreases of intracellular cAMP by FRET-based Epac sensors.

Storch U, Straub J, Erdogmus S, Gudermann T, Mederos Y Schnitzler M.

Pflugers Arch. 2017 Sep;469(9):1231-1232. doi: 10.1007/s00424-017-1985-z. No abstract available.

45.

Dynamic monitoring of Gi/o-protein-mediated decreases of intracellular cAMP by FRET-based Epac sensors.

Storch U, Straub J, Erdogmus S, Gudermann T, Mederos Y Schnitzler M.

Pflugers Arch. 2017 Jun;469(5-6):725-737. doi: 10.1007/s00424-017-1975-1. Epub 2017 Apr 6. Erratum in: Pflugers Arch. 2017 Sep;469(9):1231-1232.

46.

Assessment of TRPM7 functions by drug-like small molecules.

Chubanov V, Ferioli S, Gudermann T.

Cell Calcium. 2017 Nov;67:166-173. doi: 10.1016/j.ceca.2017.03.004. Epub 2017 Mar 14. Review.

PMID:
28356194
47.

The novel MKL target gene myoferlin modulates expansion and senescence of hepatocellular carcinoma.

Hermanns C, Hampl V, Holzer K, Aigner A, Penkava J, Frank N, Martin DE, Maier KC, Waldburger N, Roessler S, Goppelt-Struebe M, Akrap I, Thavamani A, Singer S, Nordheim A, Gudermann T, Muehlich S.

Oncogene. 2017 Jun 15;36(24):3464-3476. doi: 10.1038/onc.2016.496. Epub 2017 Jan 23.

PMID:
28114277
48.

Dynamic NHERF interaction with TRPC4/5 proteins is required for channel gating by diacylglycerol.

Storch U, Forst AL, Pardatscher F, Erdogmus S, Philipp M, Gregoritza M, Mederos Y Schnitzler M, Gudermann T.

Proc Natl Acad Sci U S A. 2017 Jan 3;114(1):E37-E46. doi: 10.1073/pnas.1612263114. Epub 2016 Dec 19.

49.

Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival.

Chubanov V, Ferioli S, Wisnowsky A, Simmons DG, Leitzinger C, Einer C, Jonas W, Shymkiv Y, Bartsch H, Braun A, Akdogan B, Mittermeier L, Sytik L, Torben F, Jurinovic V, van der Vorst EP, Weber C, Yildirim ÖA, Sotlar K, Schürmann A, Zierler S, Zischka H, Ryazanov AG, Gudermann T.

Elife. 2016 Dec 19;5. pii: e20914. doi: 10.7554/eLife.20914.

50.

Classical transient receptor potential 6 (TRPC6) channels support myofibroblast differentiation and development of experimental pulmonary fibrosis.

Hofmann K, Fiedler S, Vierkotten S, Weber J, Klee S, Jia J, Zwickenpflug W, Flockerzi V, Storch U, Yildirim AÖ, Gudermann T, Königshoff M, Dietrich A.

Biochim Biophys Acta Mol Basis Dis. 2017 Feb;1863(2):560-568. doi: 10.1016/j.bbadis.2016.12.002. Epub 2016 Dec 6.

Supplemental Content

Loading ...
Support Center