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Items: 40


prickle modulates microtubule polarity and axonal transport to ameliorate seizures in flies.

Ehaideb SN, Iyengar A, Ueda A, Iacobucci GJ, Cranston C, Bassuk AG, Gubb D, Axelrod JD, Gunawardena S, Wu CF, Manak JR.

Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):11187-92. doi: 10.1073/pnas.1403357111. Epub 2014 Jul 14.


The Drosophila serpins: multiple functions in immunity and morphogenesis.

Reichhart JM, Gubb D, Leclerc V.

Methods Enzymol. 2011;499:205-25. doi: 10.1016/B978-0-12-386471-0.00011-0.


Spn1 regulates the GNBP3-dependent Toll signaling pathway in Drosophila melanogaster.

Fullaondo A, García-Sánchez S, Sanz-Parra A, Recio E, Lee SY, Gubb D.

Mol Cell Biol. 2011 Jul;31(14):2960-72. doi: 10.1128/MCB.01397-10. Epub 2011 May 16.


Protease inhibitors and proteolytic signalling cascades in insects.

Gubb D, Sanz-Parra A, Barcena L, Troxler L, Fullaondo A.

Biochimie. 2010 Dec;92(12):1749-59. doi: 10.1016/j.biochi.2010.09.004. Epub 2010 Sep 17. Review.


Three pairs of protease-serpin complexes cooperatively regulate the insect innate immune responses.

Jiang R, Kim EH, Gong JH, Kwon HM, Kim CH, Ryu KH, Park JW, Kurokawa K, Zhang J, Gubb D, Lee BL.

J Biol Chem. 2009 Dec 18;284(51):35652-8. doi: 10.1074/jbc.M109.071001.


Identification and analysis of serpin-family genes by homology and synteny across the 12 sequenced Drosophilid genomes.

Garrett M, Fullaondo A, Troxler L, Micklem G, Gubb D.

BMC Genomics. 2009 Oct 22;10:489. doi: 10.1186/1471-2164-10-489.


Uptake of the necrotic serpin in Drosophila melanogaster via the lipophorin receptor-1.

Soukup SF, Culi J, Gubb D.

PLoS Genet. 2009 Jun;5(6):e1000532. doi: 10.1371/journal.pgen.1000532. Epub 2009 Jun 26.


Molecular dissection of Drosophila Prickle isoforms distinguishes their essential and overlapping roles in planar cell polarity.

Lin YY, Gubb D.

Dev Biol. 2009 Jan 15;325(2):386-99. doi: 10.1016/j.ydbio.2008.10.042. Epub 2008 Nov 11.


The multiple-wing-hairs gene encodes a novel GBD-FH3 domain-containing protein that functions both prior to and after wing hair initiation.

Yan J, Huen D, Morely T, Johnson G, Gubb D, Roote J, Adler PN.

Genetics. 2008 Sep;180(1):219-28. doi: 10.1534/genetics.108.091314. Epub 2008 Aug 24.


The DrosDel deletion collection: a Drosophila genomewide chromosomal deficiency resource.

Ryder E, Ashburner M, Bautista-Llacer R, Drummond J, Webster J, Johnson G, Morley T, Chan YS, Blows F, Coulson D, Reuter G, Baisch H, Apelt C, Kauk A, Rudolph T, Kube M, Klimm M, Nickel C, Szidonya J, Maróy P, Pal M, Rasmuson-Lestander A, Ekström K, Stocker H, Hugentobler C, Hafen E, Gubb D, Pflugfelder G, Dorner C, Mechler B, Schenkel H, Marhold J, Serras F, Corominas M, Punset A, Roote J, Russell S.

Genetics. 2007 Sep;177(1):615-29. Epub 2007 Aug 24.


Neuroserpin binds Abeta and is a neuroprotective component of amyloid plaques in Alzheimer disease.

Kinghorn KJ, Crowther DC, Sharp LK, Nerelius C, Davis RL, Chang HT, Green C, Gubb DC, Johansson J, Lomas DA.

J Biol Chem. 2006 Sep 29;281(39):29268-77. Epub 2006 Jul 17.


Inhibitory activity of the Drosophila melanogaster serpin Necrotic is dependent on lysine residues in the D-helix.

Robertson AS, Belorgey D, Gubb D, Dafforn TR, Lomas DA.

J Biol Chem. 2006 Sep 8;281(36):26437-43. Epub 2006 Jul 11.


Immune challenge induces N-terminal cleavage of the Drosophila serpin Necrotic.

Pelte N, Robertson AS, Zou Z, Belorgey D, Dafforn TR, Jiang H, Lomas D, Reichhart JM, Gubb D.

Insect Biochem Mol Biol. 2006 Jan;36(1):37-46. Epub 2005 Nov 8.


Intraneuronal Abeta, non-amyloid aggregates and neurodegeneration in a Drosophila model of Alzheimer's disease.

Crowther DC, Kinghorn KJ, Miranda E, Page R, Curry JA, Duthie FA, Gubb DC, Lomas DA.

Neuroscience. 2005;132(1):123-35.


The DrosDel collection: a set of P-element insertions for generating custom chromosomal aberrations in Drosophila melanogaster.

Ryder E, Blows F, Ashburner M, Bautista-Llacer R, Coulson D, Drummond J, Webster J, Gubb D, Gunton N, Johnson G, O'Kane CJ, Huen D, Sharma P, Asztalos Z, Baisch H, Schulze J, Kube M, Kittlaus K, Reuter G, Maroy P, Szidonya J, Rasmuson-Lestander A, Ekström K, Dickson B, Hugentobler C, Stocker H, Hafen E, Lepesant JA, Pflugfelder G, Heisenberg M, Mechler B, Serras F, Corominas M, Schneuwly S, Preat T, Roote J, Russell S.

Genetics. 2004 Jun;167(2):797-813.


Drosophila necrotic mutations mirror disease-associated variants of human serpins.

Green C, Brown G, Dafforn TR, Reichhart JM, Morley T, Lomas DA, Gubb D.

Development. 2003 Apr;130(7):1473-8.


The Drosophila immune defense against gram-negative infection requires the death protein dFADD.

Naitza S, Rossé C, Kappler C, Georgel P, Belvin M, Gubb D, Camonis J, Hoffmann JA, Reichhart JM.

Immunity. 2002 Nov;17(5):575-81.


Characterization of the necrotic protein that regulates the Toll-mediated immune response in Drosophila.

Robertson AS, Belorgey D, Lilley KS, Lomas DA, Gubb D, Dafforn TR.

J Biol Chem. 2003 Feb 21;278(8):6175-80. Epub 2002 Oct 31.


Splice-activated UAS hairpin vector gives complete RNAi knockout of single or double target transcripts in Drosophila melanogaster.

Reichhart JM, Ligoxygakis P, Naitza S, Woerfel G, Imler JL, Gubb D.

Genesis. 2002 Sep-Oct;34(1-2):160-4. No abstract available.


Prickle mediates feedback amplification to generate asymmetric planar cell polarity signaling.

Tree DR, Shulman JM, Rousset R, Scott MP, Gubb D, Axelrod JD.

Cell. 2002 May 3;109(3):371-81.


The necrotic gene in Drosophila corresponds to one of a cluster of three serpin transcripts mapping at 43A1.2.

Green C, Levashina E, McKimmie C, Dafforn T, Reichhart JM, Gubb D.

Genetics. 2000 Nov;156(3):1117-27.


The construction of the first balancer chromosome for the Mediterranean fruit fly, Ceratitis capitata.

Gourzi P, Gubb D, Livadaras Y, Caceres C, Franz G, Savakis C, Zacharopoulou A.

Mol Gen Genet. 2000 Sep;264(1-2):127-36.


The Drosophila tissue polarity gene starry night encodes a member of the protocadherin family.

Chae J, Kim MJ, Goo JH, Collier S, Gubb D, Charlton J, Adler PN, Park WJ.

Development. 1999 Dec;126(23):5421-9.


Constitutive activation of toll-mediated antifungal defense in serpin-deficient Drosophila.

Levashina EA, Langley E, Green C, Gubb D, Ashburner M, Hoffmann JA, Reichhart JM.

Science. 1999 Sep 17;285(5435):1917-9.


The balance between isoforms of the prickle LIM domain protein is critical for planar polarity in Drosophila imaginal discs.

Gubb D, Green C, Huen D, Coulson D, Johnson G, Tree D, Collier S, Roote J.

Genes Dev. 1999 Sep 1;13(17):2315-27.


Recovery of a marked translocation strain that will facilitate the isolation of balancer chromosomes in the Mediterranean fruit fly, Ceratitis capitata.

Gubb D, Zacharopoulou A, Livadaras Y, Gourzi P, Roote J, Savakis C.

Genome. 1998 Apr;41(2):256-65.


Genes controlling cellular polarity in Drosophila.

Gubb D.

Dev Suppl. 1993:269-77.


Pattern formation in the embryo and imaginal discs of Drosophila: what are the links?

Wilkins AS, Gubb D.

Dev Biol. 1991 May;145(1):1-12. Review. No abstract available.


A novel transvection phenomenon affecting the white gene of Drosophila melanogaster.

Gubb D, Ashburner M, Roote J, Davis T.

Genetics. 1990 Sep;126(1):167-76.


Chaotic names.

Ashburner M, Gubb D.

Nature. 1989 May 25;339(6222):264. No abstract available.


Spontaneous excision of a large composite transposable element of Drosophila melanogaster.

Chia W, McGill S, Karp R, Gubb D, Ashburner M.

Nature. 1985 Jul 4-10;316(6023):81-3.


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