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B Cell Reconstitution Following Alemtuzumab Induction Under a Belatacept-Based Maintenance Regimen.

Xu H, Mehta AK, Gao Q, Lee HJ, Ghali A, Guasch A, Kirk AD.

Am J Transplant. 2019 Oct 9. doi: 10.1111/ajt.15639. [Epub ahead of print]


Cis-trans proline isomers in the catalytic domain of calcineurin.

Teixeira JMC, Guasch A, Biçer A, Aranguren-Ibáñez Á, Chashmniam S, Paniagua JC, Pérez-Riba M, Fita I, Pons M.

FEBS J. 2019 Mar;286(6):1230-1239. doi: 10.1111/febs.14721. Epub 2018 Dec 31.


Losartan therapy decreases albuminuria with stable glomerular filtration and permselectivity in sickle cell anemia.

Yee ME, Lane PA, Archer DR, Joiner CH, Eckman JR, Guasch A.

Blood Cells Mol Dis. 2018 Mar;69:65-70. doi: 10.1016/j.bcmd.2017.09.006. Epub 2017 Sep 21.


Estimation of glomerular filtration rate using serum cystatin C and creatinine in adults with sickle cell anemia.

Yee MEM, Lane PA, Archer DR, Joiner CH, Eckman JR, Guasch A.

Am J Hematol. 2017 Oct;92(10):E598-E599. doi: 10.1002/ajh.24840. Epub 2017 Jul 29. No abstract available.


Belatacept Combined With Transient Calcineurin Inhibitor Therapy Prevents Rejection and Promotes Improved Long-Term Renal Allograft Function.

Adams AB, Goldstein J, Garrett C, Zhang R, Patzer RE, Newell KA, Turgeon NA, Chami AS, Guasch A, Kirk AD, Pastan SO, Pearson TC, Larsen CP.

Am J Transplant. 2017 Nov;17(11):2922-2936. doi: 10.1111/ajt.14353. Epub 2017 Jul 3.


Postdepletion Lymphocyte Reconstitution During Belatacept and Rapamycin Treatment in Kidney Transplant Recipients.

Xu H, Samy KP, Guasch A, Mead SI, Ghali A, Mehta A, Stempora L, Kirk AD.

Am J Transplant. 2016 Feb;16(2):550-64. doi: 10.1111/ajt.13469. Epub 2015 Oct 5.


Calcineurin Undergoes a Conformational Switch Evoked via Peptidyl-Prolyl Isomerization.

Guasch A, Aranguren-Ibáñez Á, Pérez-Luque R, Aparicio D, Martínez-Høyer S, Mulero MC, Serrano-Candelas E, Pérez-Riba M, Fita I.

PLoS One. 2015 Aug 6;10(8):e0134569. doi: 10.1371/journal.pone.0134569. eCollection 2015.


Renal transplantation using belatacept without maintenance steroids or calcineurin inhibitors.

Kirk AD, Guasch A, Xu H, Cheeseman J, Mead SI, Ghali A, Mehta AK, Wu D, Gebel H, Bray R, Horan J, Kean LS, Larsen CP, Pearson TC.

Am J Transplant. 2014 May;14(5):1142-51. doi: 10.1111/ajt.12712. Epub 2014 Mar 31.


Gene-centric association study of acute chest syndrome and painful crisis in sickle cell disease patients.

Galarneau G, Coady S, Garrett ME, Jeffries N, Puggal M, Paltoo D, Soldano K, Guasch A, Ashley-Koch AE, Telen MJ, Kutlar A, Lettre G, Papanicolaou GJ.

Blood. 2013 Jul 18;122(3):434-42. doi: 10.1182/blood-2013-01-478776. Epub 2013 May 29.


A simple and effective calibration method to determine the accuracy of liquid-handling nano-dispenser devices.

Rodríguez-Puente S, Linacero-Blanco J, Guasch A.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Mar 1;69(Pt 3):336-41. doi: 10.1107/S1744309113000791. Epub 2013 Feb 23.


Elastic and inelastic diffraction changes upon variation of the relative humidity environment of PurE crystals.

Oliete R, Pous J, Rodríguez-Puente S, Abad-Zapatero C, Guasch A.

Acta Crystallogr D Biol Crystallogr. 2013 Feb;69(Pt 2):194-212. doi: 10.1107/S090744491204454X. Epub 2013 Jan 19.


Towards on line monitoring the evolution of the myocardium infarction scar with an implantable electrical impedance spectrum monitoring system.

Sanchez B, Guasch A, Bogonez P, Galvez C, Puig V, Prat C, Semino CE, Bayes-Genis A, Bragos R.

Conf Proc IEEE Eng Med Biol Soc. 2012;2012:3223-6. doi: 10.1109/EMBC.2012.6346651.


Plasma vitamin D and parathormone are associated with obesity and atherogenic dyslipidemia: a cross-sectional study.

Guasch A, Bulló M, Rabassa A, Bonada A, Del Castillo D, Sabench F, Salas-Salvadó J.

Cardiovasc Diabetol. 2012 Dec 11;11:149. doi: 10.1186/1475-2840-11-149.


High one year mortality in adults with sickle cell disease and end-stage renal disease.

McClellan AC, Luthi JC, Lynch JR, Soucie JM, Kulkarni R, Guasch A, Huff ED, Gilbertson D, McClellan WM, DeBaun MR.

Br J Haematol. 2012 Nov;159(3):360-7. doi: 10.1111/bjh.12024. Epub 2012 Sep 12.


Humidity control can compensate for the damage induced in protein crystals by alien solutions.

Abad-Zapatero C, Oliete R, Rodriguez-Puente S, Pous J, Martinelli L, Johnson ME, Guasch A.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Oct 1;67(Pt 10):1300-8. doi: 10.1107/S174430911103377X. Epub 2011 Sep 29.


Chronic kidney disease and albuminuria in children with sickle cell disease.

McPherson Yee M, Jabbar SF, Osunkwo I, Clement L, Lane PA, Eckman JR, Guasch A.

Clin J Am Soc Nephrol. 2011 Nov;6(11):2628-33. doi: 10.2215/CJN.01600211. Epub 2011 Sep 22.


Assessment of efficacy and safety of FK778 in comparison with standard care in renal transplant recipients with untreated BK nephropathy.

Guasch A, Roy-Chaudhury P, Woodle ES, Fitzsimmons W, Holman J, First MR; FK778 BK Nephropathy Study Group.

Transplantation. 2010 Oct 27;90(8):891-7. doi: 10.1097/TP.0b013e3181f2c94b.


Improving renal outcomes in chronic anemia: learning from paroxysmal nocturnal hemoglobinuria.

Guasch A.

Am J Hematol. 2010 Aug;85(8):551-2. doi: 10.1002/ajh.21800. No abstract available.


A prospective, open-label trial of sirolimus in the treatment of focal segmental glomerulosclerosis.

Tumlin JA, Miller D, Near M, Selvaraj S, Hennigar R, Guasch A.

Clin J Am Soc Nephrol. 2006 Jan;1(1):109-16. Epub 2005 Nov 30.


Transplanting the highly sensitized patient: The emory algorithm.

Bray RA, Nolen JD, Larsen C, Pearson T, Newell KA, Kokko K, Guasch A, Tso P, Mendel JB, Gebel HM.

Am J Transplant. 2006 Oct;6(10):2307-15. Epub 2006 Aug 25.


Glomerular involvement in adults with sickle cell hemoglobinopathies: Prevalence and clinical correlates of progressive renal failure.

Guasch A, Navarrete J, Nass K, Zayas CF.

J Am Soc Nephrol. 2006 Aug;17(8):2228-35. Epub 2006 Jul 12.


Unveiling the molecular mechanism of a conjugative relaxase: The structure of TrwC complexed with a 27-mer DNA comprising the recognition hairpin and the cleavage site.

Boer R, Russi S, Guasch A, Lucas M, Blanco AG, Pérez-Luque R, Coll M, de la Cruz F.

J Mol Biol. 2006 May 5;358(3):857-69. Epub 2006 Feb 28.


The clinical epidemiology and course of the spectrum of renal diseases associated with HIV infection.

Szczech LA, Gupta SK, Habash R, Guasch A, Kalayjian R, Appel R, Fields TA, Svetkey LP, Flanagan KH, Klotman PE, Winston JA.

Kidney Int. 2004 Sep;66(3):1145-52.


Equivalent pharmacokinetics of mycophenolate mofetil in African-American and Caucasian male and female stable renal allograft recipients.

Pescovitz MD, Guasch A, Gaston R, Rajagopalan P, Tomlanovich S, Weinstein S, Bumgardner GL, Melton L, Ducray PS, Banken L, Hall J, Boutouyrie BX.

Am J Transplant. 2003 Dec;3(12):1581-6. Erratum in: Am J Transplant. 2004 Nov;4(11):1928.


Recognition and processing of the origin of transfer DNA by conjugative relaxase TrwC.

Guasch A, Lucas M, Moncalián G, Cabezas M, Pérez-Luque R, Gomis-Rüth FX, de la Cruz F, Coll M.

Nat Struct Biol. 2003 Dec;10(12):1002-10. Epub 2003 Nov 16. Erratum in: Nat Struct Biol. 2004 Jan;11(1):102.


Transmission of West Nile virus from an organ donor to four transplant recipients.

Iwamoto M, Jernigan DB, Guasch A, Trepka MJ, Blackmore CG, Hellinger WC, Pham SM, Zaki S, Lanciotti RS, Lance-Parker SE, DiazGranados CA, Winquist AG, Perlino CA, Wiersma S, Hillyer KL, Goodman JL, Marfin AA, Chamberland ME, Petersen LR; West Nile Virus in Transplant Recipients Investigation Team.

N Engl J Med. 2003 May 29;348(22):2196-203.


Note to the Paper by Guasch et al. (2002) Detailed Architecture of a DNA Translocating Machine: The High-resolution Structure of the Bacteriophage ϕ29 Connector Particle.

Guasch A, Pous J, Ibarra B, Gomis-Rüth FX, Valpuesta JM, Sousa N, Carrascosa JL, Coll M, Simpson AA, Tao Y, Leiman PG, Badasso MO, He Y, Jardine PJ, Olson NH, Morais MC, Grimes S, Anderson DL, Baker TS, Rossmann MG.

J Mol Biol. 2002 Aug 9;321(2):379-380. No abstract available.


Three-dimensional structure of human tubulin chaperone cofactor A.

Guasch A, Aloria K, Pérez R, Avila J, Zabala JC, Coll M.

J Mol Biol. 2002 May 10;318(4):1139-49.


Detailed architecture of a DNA translocating machine: the high-resolution structure of the bacteriophage phi29 connector particle.

Guasch A, Pous J, Ibarra B, Gomis-Rüth FX, Valpuesta JM, Sousa N, Carrascosa JL, Coll M.

J Mol Biol. 2002 Jan 25;315(4):663-76. Erratum in: J Mol Biol 2002 Aug 9;321(2):379-80.


Early glomerular dysfunction in human renal allografts.

Zayas CF, Guasch A.

Kidney Int. 2001 Nov;60(5):1938-47.


The structure of an engineered domain-swapped ribonuclease dimer and its implications for the evolution of proteins toward oligomerization.

Canals A, Pous J, Guasch A, Benito A, Ribó M, Vilanova M, Coll M.

Structure. 2001 Oct;9(10):967-76.


Review: postchaperonin tubulin folding cofactors and their role in microtubule dynamics.

Lopez-Fanarraga M, Avila J, Guasch A, Coll M, Zabala JC.

J Struct Biol. 2001 Aug;135(2):219-29. Review.


F(2)-isoprostanes mediate high glucose-induced TGF-beta synthesis and glomerular proteinuria in experimental type I diabetes.

Montero A, Munger KA, Khan RZ, Valdivielso JM, Morrow JD, Guasch A, Ziyadeh FN, Badr KF.

Kidney Int. 2000 Nov;58(5):1963-72.


Three-dimensional structure of a human pancreatic ribonuclease variant, a step forward in the design of cytotoxic ribonucleases.

Pous J, Canals A, Terzyan SS, Guasch A, Benito A, Ribó M, Vilanova M, Coll M.

J Mol Biol. 2000 Oct 13;303(1):49-60.


Evidence that microdeletions in the alpha globin gene protect against the development of sickle cell glomerulopathy in humans.

Guasch A, Zayas CF, Eckman JR, Muralidharan K, Zhang W, Elsas LJ.

J Am Soc Nephrol. 1999 May;10(5):1014-9.


Overexpression, purification, crystallization and preliminary X-ray diffraction analysis of the receiver domain of PhoB.

Sol M, Gomis-Rüth F, Guasch A, Serrano L, Coll M.

Acta Crystallogr D Biol Crystallogr. 1998 Nov 1;54(Pt 6 Pt 2):1460-3.


Cloning, overexpression, crystallization and preliminary X-ray analysis of a family 1 beta--glucosidase from Streptomyces.

Guasch A, Vallmitjana M, Pérez R, Querol E, Pérez-Pons JA, Coll M.

Acta Crystallogr D Biol Crystallogr. 1999 Mar;55(Pt 3):679-82.


The structure of plasmid-encoded transcriptional repressor CopG unliganded and bound to its operator.

Gomis-Rüth FX, Solá M, Acebo P, Párraga A, Guasch A, Eritja R, González A, Espinosa M, del Solar G, Coll M.

EMBO J. 1998 Dec 15;17(24):7404-15.


The subsites structure of bovine pancreatic ribonuclease A accounts for the abnormal kinetic behavior with cytidine 2',3'-cyclic phosphate.

Moussaoui M, Nogués MV, Guasch A, Barman T, Travers F, Cuchillo CM.

J Biol Chem. 1998 Oct 2;273(40):25565-72.


Crystallographic analysis reveals the 12-fold symmetry of the bacteriophage phi29 connector particle.

Guasch A, Pous J, Párraga A, Valpuesta JM, Carrascosa JL, Coll M.

J Mol Biol. 1998 Aug 14;281(2):219-25.


Purification, crystallization and preliminary X-ray diffraction studies of the bacteriophage phi29 connector particle.

Guasch A, Parrága A, Pous J, Valpuesta JM, Carrascosa JL, Coll M.

FEBS Lett. 1998 Jul 3;430(3):283-7.


Sickle cell anemia causes a distinct pattern of glomerular dysfunction.

Guasch A, Cua M, You W, Mitch WE.

Kidney Int. 1997 Mar;51(3):826-33.


The role of non-catalytic binding subsites in the endonuclease activity of bovine pancreatic ribonuclease A.

Moussaoui M, Guasch A, Boix E, Cuchillo C, Nogués M.

J Biol Chem. 1996 Mar 1;271(9):4687-92.


Mechanisms of proteinuria in nephrotic humans.

Myers BD, Guasch A.

Pediatr Nephrol. 1994 Feb;8(1):107-12. Review.


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