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Items: 38

1.

Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells.

Niogret C, Miah SMS, Rota G, Fonta NP, Wang H, Held W, Birchmeier W, Sexl V, Yang W, Vivier E, Ho PC, Brossay L, Guarda G.

Nat Commun. 2019 Mar 29;10(1):1444. doi: 10.1038/s41467-019-09431-3.

2.

The transcription factor Rfx7 limits metabolism of NK cells and promotes their maintenance and immunity.

Castro W, Chelbi ST, Niogret C, Ramon-Barros C, Welten SPM, Osterheld K, Wang H, Rota G, Morgado L, Vivier E, Raeber ME, Boyman O, Delorenzi M, Barras D, Ho PC, Oxenius A, Guarda G.

Nat Immunol. 2018 Aug;19(8):809-820. doi: 10.1038/s41590-018-0144-9. Epub 2018 Jul 2.

3.

Shp-2 Is Dispensable for Establishing T Cell Exhaustion and for PD-1 Signaling In Vivo.

Rota G, Niogret C, Dang AT, Barros CR, Fonta NP, Alfei F, Morgado L, Zehn D, Birchmeier W, Vivier E, Guarda G.

Cell Rep. 2018 Apr 3;23(1):39-49. doi: 10.1016/j.celrep.2018.03.026.

4.

The regulatory network behind MHC class I expression.

Jongsma MLM, Guarda G, Spaapen RM.

Mol Immunol. 2017 Dec 7. pii: S0161-5890(17)30598-9. doi: 10.1016/j.molimm.2017.12.005. [Epub ahead of print]

5.

OM-85 is an immunomodulator of interferon-β production and inflammasome activity.

Dang AT, Pasquali C, Ludigs K, Guarda G.

Sci Rep. 2017 Mar 6;7:43844. doi: 10.1038/srep43844.

6.

Emerging Major Histocompatibility Complex Class I-Related Functions of NLRC5.

Chelbi ST, Dang AT, Guarda G.

Adv Immunol. 2017;133:89-119. doi: 10.1016/bs.ai.2016.11.003. Epub 2017 Jan 3. Review.

PMID:
28215281
7.

NLRC5, a promising new entry in tumor immunology.

Chelbi ST, Guarda G.

J Immunother Cancer. 2016 Jul 19;4:39. doi: 10.1186/s40425-016-0143-z. eCollection 2016.

8.

T Cell Priming by Activated Nlrc5-Deficient Dendritic Cells Is Unaffected despite Partially Reduced MHC Class I Levels.

Rota G, Ludigs K, Siegert S, Tardivel A, Morgado L, Reith W, De Gassart A, Guarda G.

J Immunol. 2016 Apr 1;196(7):2939-46. doi: 10.4049/jimmunol.1502084. Epub 2016 Mar 4.

9.

NLRC5 shields T lymphocytes from NK-cell-mediated elimination under inflammatory conditions.

Ludigs K, Jandus C, Utzschneider DT, Staehli F, Bessoles S, Dang AT, Rota G, Castro W, Zehn D, Vivier E, Held W, Romero P, Guarda G.

Nat Commun. 2016 Feb 10;7:10554. doi: 10.1038/ncomms10554.

10.

Strengthening of Porcelain Provided by Resin Cements and Flowable Composites.

Spazzin AO, Guarda GB, Oliveira-Ogliari A, Leal FB, Correr-Sobrinho L, Moraes RR.

Oper Dent. 2016 Mar-Apr;41(2):179-88. doi: 10.2341/15-025-L. Epub 2015 Aug 12.

PMID:
26266657
11.

NLRC5 exclusively transactivates MHC class I and related genes through a distinctive SXY module.

Ludigs K, Seguín-Estévez Q, Lemeille S, Ferrero I, Rota G, Chelbi S, Mattmann C, MacDonald HR, Reith W, Guarda G.

PLoS Genet. 2015 Mar 26;11(3):e1005088. doi: 10.1371/journal.pgen.1005088. eCollection 2015 Mar.

12.

NLRC5, at the Heart of Antigen Presentation.

Neerincx A, Castro W, Guarda G, Kufer TA.

Front Immunol. 2013 Nov 22;4:397. doi: 10.3389/fimmu.2013.00397. Review.

13.

The Nlrp3 inflammasome regulates acute graft-versus-host disease.

Jankovic D, Ganesan J, Bscheider M, Stickel N, Weber FC, Guarda G, Follo M, Pfeifer D, Tardivel A, Ludigs K, Bouazzaoui A, Kerl K, Fischer JC, Haas T, Schmitt-Gräff A, Manoharan A, Müller L, Finke J, Martin SF, Gorka O, Peschel C, Ruland J, Idzko M, Duyster J, Holler E, French LE, Poeck H, Contassot E, Zeiser R.

J Exp Med. 2013 Sep 23;210(10):1899-910. doi: 10.1084/jem.20130084. Epub 2013 Aug 26.

14.

Omega-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation.

Yan Y, Jiang W, Spinetti T, Tardivel A, Castillo R, Bourquin C, Guarda G, Tian Z, Tschopp J, Zhou R.

Immunity. 2013 Jun 27;38(6):1154-63. doi: 10.1016/j.immuni.2013.05.015.

15.

Innate receptors for adaptive immunity.

Michallet MC, Rota G, Maslowski K, Guarda G.

Curr Opin Microbiol. 2013 Jun;16(3):296-302. doi: 10.1016/j.mib.2013.04.003. Epub 2013 May 7. Review.

PMID:
23659869
16.

Innate and adaptive effects of inflammasomes on T cell responses.

Dostert C, Ludigs K, Guarda G.

Curr Opin Immunol. 2013 Jun;25(3):359-65. doi: 10.1016/j.coi.2013.02.008. Epub 2013 Mar 7. Review.

PMID:
23478069
17.

Periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis syndrome is linked to dysregulated monocyte IL-1β production.

Kolly L, Busso N, von Scheven-Gete A, Bagnoud N, Moix I, Holzinger D, Simon G, Ives A, Guarda G, So A, Morris MA, Hofer M.

J Allergy Clin Immunol. 2013 Jun;131(6):1635-43. doi: 10.1016/j.jaci.2012.07.043. Epub 2012 Sep 21.

PMID:
23006543
18.

Effects of surface treatments, thermocycling, and cyclic loading on the bond strength of a resin cement bonded to a lithium disilicate glass ceramic.

Guarda GB, Correr AB, Gonçalves LS, Costa AR, Borges GA, Sinhoreti MA, Correr-Sobrinho L.

Oper Dent. 2013 Mar-Apr;38(2):208-17. doi: 10.2341/11-076-L. Epub 2012 Aug 3.

PMID:
22856682
19.

Type I IFN-mediated regulation of IL-1 production in inflammatory disorders.

Ludigs K, Parfenov V, Du Pasquier RA, Guarda G.

Cell Mol Life Sci. 2012 Oct;69(20):3395-418. doi: 10.1007/s00018-012-0989-2. Epub 2012 Apr 24. Review.

PMID:
22527721
20.

Inflammasome activators induce interleukin-1α secretion via distinct pathways with differential requirement for the protease function of caspase-1.

Gross O, Yazdi AS, Thomas CJ, Masin M, Heinz LX, Guarda G, Quadroni M, Drexler SK, Tschopp J.

Immunity. 2012 Mar 23;36(3):388-400. doi: 10.1016/j.immuni.2012.01.018.

21.

NLRC5 deficiency selectively impairs MHC class I- dependent lymphocyte killing by cytotoxic T cells.

Staehli F, Ludigs K, Heinz LX, Seguín-Estévez Q, Ferrero I, Braun M, Schroder K, Rebsamen M, Tardivel A, Mattmann C, MacDonald HR, Romero P, Reith W, Guarda G, Tschopp J.

J Immunol. 2012 Apr 15;188(8):3820-8. doi: 10.4049/jimmunol.1102671. Epub 2012 Mar 12.

22.

Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation.

Vince JE, Wong WW, Gentle I, Lawlor KE, Allam R, O'Reilly L, Mason K, Gross O, Ma S, Guarda G, Anderton H, Castillo R, Häcker G, Silke J, Tschopp J.

Immunity. 2012 Feb 24;36(2):215-27. doi: 10.1016/j.immuni.2012.01.012.

23.

NLRC4 inflammasomes in dendritic cells regulate noncognate effector function by memory CD8⁺ T cells.

Kupz A, Guarda G, Gebhardt T, Sander LE, Short KR, Diavatopoulos DA, Wijburg OL, Cao H, Waithman JC, Chen W, Fernandez-Ruiz D, Whitney PG, Heath WR, Curtiss R 3rd, Tschopp J, Strugnell RA, Bedoui S.

Nat Immunol. 2012 Jan 8;13(2):162-9. doi: 10.1038/ni.2195.

PMID:
22231517
24.

The inflammasome: an integrated view.

Gross O, Thomas CJ, Guarda G, Tschopp J.

Immunol Rev. 2011 Sep;243(1):136-51. doi: 10.1111/j.1600-065X.2011.01046.x. Review.

PMID:
21884173
25.

NLRX1/NOD5 deficiency does not affect MAVS signalling.

Rebsamen M, Vazquez J, Tardivel A, Guarda G, Curran J, Tschopp J.

Cell Death Differ. 2011 Aug;18(8):1387. doi: 10.1038/cdd.2011.64. Epub 2011 May 27. No abstract available.

26.

Type I interferon inhibits interleukin-1 production and inflammasome activation.

Guarda G, Braun M, Staehli F, Tardivel A, Mattmann C, Förster I, Farlik M, Decker T, Du Pasquier RA, Romero P, Tschopp J.

Immunity. 2011 Feb 25;34(2):213-23. doi: 10.1016/j.immuni.2011.02.006.

27.

Differential expression of NLRP3 among hematopoietic cells.

Guarda G, Zenger M, Yazdi AS, Schroder K, Ferrero I, Menu P, Tardivel A, Mattmann C, Tschopp J.

J Immunol. 2011 Feb 15;186(4):2529-34. doi: 10.4049/jimmunol.1002720. Epub 2011 Jan 21.

28.

Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1α and IL-1β.

Yazdi AS, Guarda G, Riteau N, Drexler SK, Tardivel A, Couillin I, Tschopp J.

Proc Natl Acad Sci U S A. 2010 Nov 9;107(45):19449-54. doi: 10.1073/pnas.1008155107. Epub 2010 Oct 25.

29.

Luting glass ceramic restorations using a self-adhesive resin cement under different dentin conditions.

Guarda GB, Gonçalves LS, Correr AB, Moraes RR, Sinhoreti MA, Correr-Sobrinho L.

J Appl Oral Sci. 2010 May-Jun;18(3):244-8.

30.

Regulation of inflammasome activity.

Guarda G, So A.

Immunology. 2010 Jul;130(3):329-36. doi: 10.1111/j.1365-2567.2010.03283.x. Epub 2010 May 10. Review.

31.

Inflammatory caspases in innate immunity and inflammation.

Yazdi AS, Guarda G, D'Ombrain MC, Drexler SK.

J Innate Immun. 2010;2(3):228-37. doi: 10.1159/000283688. Epub 2010 Feb 10. Review.

32.

Malarial hemozoin is a Nalp3 inflammasome activating danger signal.

Dostert C, Guarda G, Romero JF, Menu P, Gross O, Tardivel A, Suva ML, Stehle JC, Kopf M, Stamenkovic I, Corradin G, Tschopp J.

PLoS One. 2009 Aug 4;4(8):e6510. doi: 10.1371/journal.pone.0006510.

33.

T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes.

Guarda G, Dostert C, Staehli F, Cabalzar K, Castillo R, Tardivel A, Schneider P, Tschopp J.

Nature. 2009 Jul 9;460(7252):269-73. doi: 10.1038/nature08100. Epub 2009 Jun 3.

PMID:
19494813
34.

CD40L+ CD4+ memory T cells migrate in a CD62P-dependent fashion into reactive lymph nodes and license dendritic cells for T cell priming.

Martín-Fontecha A, Baumjohann D, Guarda G, Reboldi A, Hons M, Lanzavecchia A, Sallusto F.

J Exp Med. 2008 Oct 27;205(11):2561-74. doi: 10.1084/jem.20081212. Epub 2008 Oct 6.

35.

The strength of T cell stimulation determines IL-7 responsiveness, secondary expansion, and lineage commitment of primed human CD4+IL-7Rhi T cells.

Lozza L, Rivino L, Guarda G, Jarrossay D, Rinaldi A, Bertoni F, Sallusto F, Lanzavecchia A, Geginat J.

Eur J Immunol. 2008 Jan;38(1):30-9.

36.

L-selectin-negative CCR7- effector and memory CD8+ T cells enter reactive lymph nodes and kill dendritic cells.

Guarda G, Hons M, Soriano SF, Huang AY, Polley R, Martín-Fontecha A, Stein JV, Germain RN, Lanzavecchia A, Sallusto F.

Nat Immunol. 2007 Jul;8(7):743-52. Epub 2007 May 27.

PMID:
17529983
37.

Gasterophilus pecorum larvae in an aged lion.

Battisti A, Panfili G, Di Guarda G, Principato M.

Vet Rec. 1997 Jun 21;140(25):664. No abstract available.

PMID:
9226855
38.

[Our experience in the surgery of bile ducts].

Spagliardi E, Guarda G, Parini U, Palombo D.

Minerva Chir. 1976 Mar 31;31(6):245-50. Italian.

PMID:
1004739

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