Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 579


Sarcoplasmic reticulum calcium leak contributes to arrhythmia but not to heart failure progression.

Mohamed BA, Hartmann N, Tirilomis P, Sekeres K, Li W, Neef S, Richter C, Zeisberg EM, Kattner L, Didié M, Guan K, Schmitto JD, Lehnart SE, Luther S, Voigt N, Seidler T, Sossalla S, Hasenfuss G, Toischer K.

Sci Transl Med. 2018 Sep 12;10(458). pii: eaan0724. doi: 10.1126/scitranslmed.aan0724.


The Molecular Mechanisms of Protective Role of Se on the G0/G1 Phase Arrest Caused by AFB1 in Broiler's Thymocytes.

Guan K, Li H, Zuo Z, Wang F, Hu P, Peng X, Fang J, Cui H, Shu G, Ouyang P.

Biol Trace Elem Res. 2018 Sep 10. doi: 10.1007/s12011-018-1491-y. [Epub ahead of print]


Emergent Life Events: An In-Depth Investigation of Characteristics and Provider Responses during Youth Evidence-Based Treatment.

Guan K, Kim RE, Rodas NV, Brown TE, Gamarra JM, Krull JL, Chorpita BF.

J Clin Child Adolesc Psychol. 2018 Aug 24:1-16. doi: 10.1080/15374416.2018.1496441. [Epub ahead of print]


RAP2 mediates mechanoresponses of the Hippo pathway.

Meng Z, Qiu Y, Lin KC, Kumar A, Placone JK, Fang C, Wang KC, Lu S, Pan M, Hong AW, Moroishi T, Luo M, Plouffe SW, Diao Y, Ye Z, Park HW, Wang X, Yu FX, Chien S, Wang CY, Ren B, Engler AJ, Guan KL.

Nature. 2018 Aug;560(7720):655-660. doi: 10.1038/s41586-018-0444-0. Epub 2018 Aug 22.


Interplay between YAP/TAZ and Metabolism.

Koo JH, Guan KL.

Cell Metab. 2018 Aug 7;28(2):196-206. doi: 10.1016/j.cmet.2018.07.010. Review.


Efficacy of montelukast as prophylactic treatment for seasonal allergic rhinitis.

Li L, Wang R, Cui L, Guan K.

Ear Nose Throat J. 2018 Jul;97(7):E12-E16.


Author Correction: Regulation of Hippo pathway transcription factor TEAD by p38 MAPK-induced cytoplasmic translocation.

Lin KC, Moroishi T, Meng Z, Jeong HS, Plouffe SW, Sekido Y, Han J, Park HW, Guan KL.

Nat Cell Biol. 2018 Sep;20(9):1098. doi: 10.1038/s41556-018-0101-8.


Opposing Tumor-Promoting and -Suppressive Functions of Rictor/mTORC2 Signaling in Adult Glioma and Pediatric SHH Medulloblastoma.

Akgül S, Li Y, Zheng S, Kool M, Treisman DM, Li C, Wang Y, Gröbner S, Ikenoue T, Shen Y, Camelo-Piragua S, Tomasek G, Stark S, Guduguntla V, Gusella JF, Guan KL, Pfister SM, Verhaak RGW, Zhu Y.

Cell Rep. 2018 Jul 10;24(2):463-478.e5. doi: 10.1016/j.celrep.2018.06.050.


Assembly and activation of the Hippo signalome by FAT1 tumor suppressor.

Martin D, Degese MS, Vitale-Cross L, Iglesias-Bartolome R, Valera JLC, Wang Z, Feng X, Yeerna H, Vadmal V, Moroishi T, Thorne RF, Zaida M, Siegele B, Cheong SC, Molinolo AA, Samuels Y, Tamayo P, Guan KL, Lippman SM, Lyons JG, Gutkind JS.

Nat Commun. 2018 Jul 9;9(1):2372. doi: 10.1038/s41467-018-04590-1.


FluoSpec 2-An Automated Field Spectroscopy System to Monitor Canopy Solar-Induced Fluorescence.

Yang X, Shi H, Stovall A, Guan K, Miao G, Zhang Y, Zhang Y, Xiao X, Ryu Y, Lee JE.

Sensors (Basel). 2018 Jun 28;18(7). pii: E2063. doi: 10.3390/s18072063.


Deep phenotyping of human induced pluripotent stem cell-derived atrial and ventricular cardiomyocytes.

Cyganek L, Tiburcy M, Sekeres K, Gerstenberg K, Bohnenberger H, Lenz C, Henze S, Stauske M, Salinas G, Zimmermann WH, Hasenfuss G, Guan K.

JCI Insight. 2018 Jun 21;3(12). pii: 99941. doi: 10.1172/jci.insight.99941. [Epub ahead of print]


Polycystic kidney disease: a Hippo connection.

Ma S, Guan KL.

Genes Dev. 2018 Jun 1;32(11-12):737-739. doi: 10.1101/gad.316570.118. Review.


YAP and MRTF-A, transcriptional co-activators of RhoA-mediated gene expression, are critical for glioblastoma tumorigenicity.

Yu OM, Benitez JA, Plouffe SW, Ryback D, Klein A, Smith J, Greenbaum J, Delatte B, Rao A, Guan KL, Furnari FB, Chaim OM, Miyamoto S, Brown JH.

Oncogene. 2018 Jun 11. doi: 10.1038/s41388-018-0301-5. [Epub ahead of print]


The Hippo pathway effector proteins YAP and TAZ have both distinct and overlapping functions in the cell.

Plouffe SW, Lin KC, Moore JL 3rd, Tan FE, Ma S, Ye Z, Qiu Y, Ren B, Guan KL.

J Biol Chem. 2018 Jul 13;293(28):11230-11240. doi: 10.1074/jbc.RA118.002715. Epub 2018 May 25.


[Effects of double-dose antihistamine or combined therapy in allergic rhinitis].

Li LS, Guan K, Cui L, Wang RQ.

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2018 Jan 5;32(1):27-32. doi: 10.13201/j.issn.1001-1781.2018.01.006. Chinese.


[The clinical value of China Savin pollen extract used for skin prick test].

Guan K, Zhou JX, Wang RQ, Yin J, Wang LL, Zhi YX, Sun JL, Li H, Wen LP, Gu JQ, Tang R, Wang ZX, Li LS, Xu T.

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2018 Feb;32(3):161-166. doi: 10.13201/j.issn.1001-1781.2018.03.001. Chinese.


Satellite sun-induced chlorophyll fluorescence detects early response of winter wheat to heat stress in the Indian Indo-Gangetic Plains.

Song L, Guanter L, Guan K, You L, Huete A, Ju W, Zhang Y.

Glob Chang Biol. 2018 May 10. doi: 10.1111/gcb.14302. [Epub ahead of print]


Precisely Controlling Nanochannels of Graphene Oxide Membranes through Lignin-Based Cation Decoration for Dehydration of Biofuels.

Guan K, Liu Q, Ji Y, Zhang M, Wu Y, Zhao J, Liu G, Jin W.

ChemSusChem. 2018 Jul 20;11(14):2315-2320. doi: 10.1002/cssc.201800479. Epub 2018 May 25.


Incorporating Graphene Oxide into Alginate Polymer with a Cationic Intermediate To Strengthen Membrane Dehydration Performance.

Guan K, Liang F, Zhu H, Zhao J, Jin W.

ACS Appl Mater Interfaces. 2018 Apr 25;10(16):13903-13913. doi: 10.1021/acsami.8b04093. Epub 2018 Apr 10.


MicroRNAs in cardiomyocyte differentiation and maturation.

Alfar EA, El-Armouche A, Guan K.

Cardiovasc Res. 2018 May 1;114(6):779-781. doi: 10.1093/cvr/cvy065. No abstract available.


Identification of STOP1-Like Proteins Associated With Aluminum Tolerance in Sweet Sorghum (Sorghum bicolor L.).

Huang S, Gao J, You J, Liang Y, Guan K, Yan S, Zhan M, Yang Z.

Front Plant Sci. 2018 Feb 28;9:258. doi: 10.3389/fpls.2018.00258. eCollection 2018.


A LATS biosensor screen identifies VEGFR as a regulator of the Hippo pathway in angiogenesis.

Azad T, Janse van Rensburg HJ, Lightbody ED, Neveu B, Champagne A, Ghaffari A, Kay VR, Hao Y, Shen H, Yeung B, Croy BA, Guan KL, Pouliot F, Zhang J, Nicol CJB, Yang X.

Nat Commun. 2018 Mar 13;9(1):1061. doi: 10.1038/s41467-018-03278-w.


The Protective Role of Selenium in AFB1-Induced Tissue Damage and Cell Cycle Arrest in Chicken's Bursa of Fabricius.

Hu P, Zuo Z, Wang F, Peng X, Guan K, Li H, Fang J, Cui H, Su G, Ouyang P, Zhou Y.

Biol Trace Elem Res. 2018 Oct;185(2):486-496. doi: 10.1007/s12011-018-1273-6. Epub 2018 Mar 6.


SIRT5 inhibits peroxisomal ACOX1 to prevent oxidative damage and is downregulated in liver cancer.

Chen XF, Tian MX, Sun RQ, Zhang ML, Zhou LS, Jin L, Chen LL, Zhou WJ, Duan KL, Chen YJ, Gao C, Cheng ZL, Wang F, Zhang JY, Sun YP, Yu HX, Zhao YZ, Yang Y, Liu WR, Shi YH, Xiong Y, Guan KL, Ye D.

EMBO Rep. 2018 May;19(5). pii: e45124. doi: 10.15252/embr.201745124. Epub 2018 Feb 28.


Metabolism, Activity, and Targeting of D- and L-2-Hydroxyglutarates.

Ye D, Guan KL, Xiong Y.

Trends Cancer. 2018 Feb;4(2):151-165. doi: 10.1016/j.trecan.2017.12.005. Epub 2018 Jan 5. Review.


Unintended Consequences of Evidence-Based Treatment Policy Reform: Is Implementation the Goal or the Strategy for Higher Quality Care?

Park AL, Tsai KH, Guan K, Chorpita BF.

Adm Policy Ment Health. 2018 Jul;45(4):649-660. doi: 10.1007/s10488-018-0853-2.


Curcumin induces apoptosis and inhibits proliferation in infantile hemangioma endothelial cells via downregulation of MCL-1 and HIF-1α.

Lou S, Wang Y, Yu Z, Guan K, Kan Q.

Medicine (Baltimore). 2018 Feb;97(7):e9562. doi: 10.1097/MD.0000000000009562.


Acetylation accumulates PFKFB3 in cytoplasm to promote glycolysis and protects cells from cisplatin-induced apoptosis.

Li FL, Liu JP, Bao RX, Yan G, Feng X, Xu YP, Sun YP, Yan W, Ling ZQ, Xiong Y, Guan KL, Yuan HX.

Nat Commun. 2018 Feb 6;9(1):508. doi: 10.1038/s41467-018-02950-5.


Claudin-18-mediated YAP activity regulates lung stem and progenitor cell homeostasis and tumorigenesis.

Zhou B, Flodby P, Luo J, Castillo DR, Liu Y, Yu FX, McConnell A, Varghese B, Li G, Chimge NO, Sunohara M, Koss MN, Elatre W, Conti P, Liebler JM, Yang C, Marconett CN, Laird-Offringa IA, Minoo P, Guan K, Stripp BR, Crandall ED, Borok Z.

J Clin Invest. 2018 Mar 1;128(3):970-984. doi: 10.1172/JCI90429. Epub 2018 Feb 5.


Metabolic reprogramming by PCK1 promotes TCA cataplerosis, oxidative stress and apoptosis in liver cancer cells and suppresses hepatocellular carcinoma.

Liu MX, Jin L, Sun SJ, Liu P, Feng X, Cheng ZL, Liu WR, Guan KL, Shi YH, Yuan HX, Xiong Y.

Oncogene. 2018 Mar;37(12):1637-1653. doi: 10.1038/s41388-017-0070-6. Epub 2018 Jan 16.


The Hippo pathway in organ development, homeostasis, and regeneration.

Fu V, Plouffe SW, Guan KL.

Curr Opin Cell Biol. 2017 Dec;49:99-107. doi: 10.1016/ Epub 2018 Jan 6. Review.


Colonic epithelium rejuvenation through YAP/TAZ.

Chen R, Guan KL.

EMBO J. 2018 Jan 17;37(2):164-166. doi: 10.15252/embj.201798618. Epub 2017 Dec 27. No abstract available.


N-P Fertilization Inhibits Growth of Root Hemiparasite Pedicularis kansuensis in Natural Grassland.

Liu Y, Taxipulati T, Gong Y, Sui X, Wang X, Parent SÉ, Hu Y, Guan K, Li A.

Front Plant Sci. 2017 Dec 7;8:2088. doi: 10.3389/fpls.2017.02088. eCollection 2017.


Biological processes dominate seasonality of remotely sensed canopy greenness in an Amazon evergreen forest.

Wu J, Kobayashi H, Stark SC, Meng R, Guan K, Tran NN, Gao S, Yang W, Restrepo-Coupe N, Miura T, Oliviera RC, Rogers A, Dye DG, Nelson BW, Serbin SP, Huete AR, Saleska SR.

New Phytol. 2018 Mar;217(4):1507-1520. doi: 10.1111/nph.14939. Epub 2017 Dec 23.


A Remote Health Monitoring System for the Elderly Based on Smart Home Gateway.

Guan K, Shao M, Wu S.

J Healthc Eng. 2017;2017:5843504. doi: 10.1155/2017/5843504. Epub 2017 Oct 24.


Glut3 Addiction Is a Druggable Vulnerability for a Molecularly Defined Subpopulation of Glioblastoma.

Cosset É, Ilmjärv S, Dutoit V, Elliott K, von Schalscha T, Camargo MF, Reiss A, Moroishi T, Seguin L, Gomez G, Moo JS, Preynat-Seauve O, Krause KH, Chneiweiss H, Sarkaria JN, Guan KL, Dietrich PY, Weis SM, Mischel PS, Cheresh DA.

Cancer Cell. 2017 Dec 11;32(6):856-868.e5. doi: 10.1016/j.ccell.2017.10.016. Epub 2017 Nov 30.


miR-638 Inhibits immature Sertoli cell growth by indirectly inactivating PI3K/AKT pathway via SPAG1 gene.

Hu P, Guan K, Feng Y, Ma C, Song H, Li Y, Xia X, Li J, Li F.

Cell Cycle. 2017;16(23):2290-2300. doi: 10.1080/15384101.2017.1380130. Epub 2017 Nov 9.


Non-radioactive LATS in vitro Kinase Assay.

Hong AW, Guan KL.

Bio Protoc. 2017 Jul 20;7(14). pii: e2391. doi: 10.21769/BioProtoc.2391.


Role of angiotensin II type 2 receptor during electrophysiological remodeling of left ventricular hypertrophic myocardium in spontaneously hypertensive rats.

Xiao Y, Long WQ, Guan KP, Long M, Lu GH, Huang ZB.

J Am Soc Hypertens. 2018 Jan;12(1):58-65. doi: 10.1016/j.jash.2017.09.014. Epub 2017 Oct 13. Erratum in: J Am Soc Hypertens. 2018 Aug;12(8):633.


GP73 regulates Hepatic Steatosis by enhancing SCAP-SREBPs interaction.

Yang X, Wu F, Chen J, Wang C, Zhu Y, Li F, Hao Q, Duan C, Wang L, Ma X, Zou D, Luo L, Zhao Y, Guan K, Cao Y, Zhang P, Zhou P, Ma S, Yan Z, Li J, Zhang Y, Wei C, Zhong H.

Sci Rep. 2017 Nov 2;7(1):14932. doi: 10.1038/s41598-017-06500-9.


ScDREB8, a novel A-5 type of DREB gene in the desert moss Syntrichia caninervis, confers salt tolerance to Arabidopsis.

Liang Y, Li X, Zhang D, Gao B, Yang H, Wang Y, Guan K, Wood AJ.

Plant Physiol Biochem. 2017 Nov;120:242-251. doi: 10.1016/j.plaphy.2017.09.014. Epub 2017 Sep 22.


CLOCK Acetylates ASS1 to Drive Circadian Rhythm of Ureagenesis.

Lin R, Mo Y, Zha H, Qu Z, Xie P, Zhu ZJ, Xu Y, Xiong Y, Guan KL.

Mol Cell. 2017 Oct 5;68(1):198-209.e6. doi: 10.1016/j.molcel.2017.09.008.


Regulation of the Hippo Pathway Transcription Factor TEAD.

Lin KC, Park HW, Guan KL.

Trends Biochem Sci. 2017 Nov;42(11):862-872. doi: 10.1016/j.tibs.2017.09.003. Epub 2017 Sep 27. Review.


Severe DCM phenotype of patient harboring RBM20 mutation S635A can be modeled by patient-specific induced pluripotent stem cell-derived cardiomyocytes.

Streckfuss-Bömeke K, Tiburcy M, Fomin A, Luo X, Li W, Fischer C, Özcelik C, Perrot A, Sossalla S, Haas J, Vidal RO, Rebs S, Khadjeh S, Meder B, Bonn S, Linke WA, Zimmermann WH, Hasenfuss G, Guan K.

J Mol Cell Cardiol. 2017 Dec;113:9-21. doi: 10.1016/j.yjmcc.2017.09.008. Epub 2017 Sep 21.


CRISPR correction of the PRKAG2 gene mutation in the patient's induced pluripotent stem cell-derived cardiomyocytes eliminates electrophysiological and structural abnormalities.

Ben Jehuda R, Eisen B, Shemer Y, Mekies LN, Szantai A, Reiter I, Cui H, Guan K, Haron-Khun S, Freimark D, Sperling SR, Gherghiceanu M, Arad M, Binah O.

Heart Rhythm. 2018 Feb;15(2):267-276. doi: 10.1016/j.hrthm.2017.09.024. Epub 2017 Sep 14.


Efficient Killing of Murine Pluripotent Stem Cells by Natural Killer (NK) Cells Requires Activation by Cytokines and Partly Depends on the Activating NK Receptor NKG2D.

Gröschel C, Hübscher D, Nolte J, Monecke S, Sasse A, Elsner L, Paulus W, Trenkwalder C, Polić B, Mansouri A, Guan K, Dressel R.

Front Immunol. 2017 Jul 26;8:870. doi: 10.3389/fimmu.2017.00870. eCollection 2017.


SIRT7 deacetylates DDB1 and suppresses the activity of the CRL4 E3 ligase complexes.

Mo Y, Lin R, Liu P, Tan M, Xiong Y, Guan KL, Yuan HX.

FEBS J. 2017 Nov;284(21):3619-3636. doi: 10.1111/febs.14259. Epub 2017 Oct 10.


Hydrologic resilience and Amazon productivity.

Ahlström A, Canadell JG, Schurgers G, Wu M, Berry JA, Guan K, Jackson RB.

Nat Commun. 2017 Aug 30;8(1):387. doi: 10.1038/s41467-017-00306-z.


Catecholamine-Dependent β-Adrenergic Signaling in a Pluripotent Stem Cell Model of Takotsubo Cardiomyopathy.

Borchert T, Hübscher D, Guessoum CI, Lam TD, Ghadri JR, Schellinger IN, Tiburcy M, Liaw NY, Li Y, Haas J, Sossalla S, Huber MA, Cyganek L, Jacobshagen C, Dressel R, Raaz U, Nikolaev VO, Guan K, Thiele H, Meder B, Wollnik B, Zimmermann WH, Lüscher TF, Hasenfuss G, Templin C, Streckfuss-Bömeke K.

J Am Coll Cardiol. 2017 Aug 22;70(8):975-991. doi: 10.1016/j.jacc.2017.06.061.

Supplemental Content

Support Center