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Advances in the clinical and mechanism research of pollen induced seasonal allergic asthma.

Xie ZJ, Guan K, Yin J.

Am J Clin Exp Immunol. 2019 Feb 15;8(1):1-8. eCollection 2019. Review.


Controllable ion transport by surface-charged graphene oxide membrane.

Zhang M, Guan K, Ji Y, Liu G, Jin W, Xu N.

Nat Commun. 2019 Mar 19;10(1):1253. doi: 10.1038/s41467-019-09286-8.


Retraction: FAK and Src kinases are required for netrin-induced tyrosine phosphorylation of UNC5 (doi: 10.1242/jcs.02697).

Li W, Aurandt J, Jürgensen C, Rao Y, Guan KL.

J Cell Sci. 2019 Feb 19;132(5). pii: jcs230342. doi: 10.1242/jcs.230342. No abstract available.


Long-term survival and prognostic factors for locally advanced renal cell carcinoma with renal vein tumor thrombus.

Cao C, Bi X, Liang J, Li L, Zhang H, Xiao Z, Xiao Z, Tian J, Wang D, Guan K, Li C, Ma J, Zheng S, Shou J.

BMC Cancer. 2019 Feb 13;19(1):144. doi: 10.1186/s12885-019-5359-0.


SIRT5 deficiency suppresses mitochondrial ATP production and promotes AMPK activation in response to energy stress.

Zhang M, Wu J, Sun R, Tao X, Wang X, Kang Q, Wang H, Zhang L, Liu P, Zhang J, Xia Y, Zhao Y, Yang Y, Xiong Y, Guan KL, Zou Y, Ye D.

PLoS One. 2019 Feb 13;14(2):e0211796. doi: 10.1371/journal.pone.0211796. eCollection 2019.


Effects of aflatoxin B1 on the cell cycle distribution of splenocytes in chickens.

Li H, Guan K, Zuo Z, Wang F, Peng X, Fang J, Cui H, Zhou Y, Ouyang P, Su G, Chen Z.

J Toxicol Pathol. 2019 Jan;32(1):27-36. doi: 10.1293/tox.2018-0015. Epub 2018 Nov 18.


"Teaching Moments" in Psychotherapy: Addressing Emergent Life Events Using Strategies From a Modular Evidence-Based Treatment.

Guan K, Boustani MM, Chorpita BF.

Behav Ther. 2019 Jan;50(1):101-114. doi: 10.1016/j.beth.2018.03.014. Epub 2018 Apr 5.


Pak2 as a Novel Therapeutic Target for Cardioprotective Endoplasmic Reticulum Stress Response.

Binder P, Wang S, Radu M, Zin M, Collins L, Khan S, Li Y, Sekeres K, Humphreys N, Swanton E, Reid A, Pu F, Oceandy D, Guan K, Hille SS, Frey N, Müller OJ, Cartwright EJ, Chernoff J, Wang X, Liu W.

Circ Res. 2019 Mar;124(5):696-711. doi: 10.1161/CIRCRESAHA.118.312829.


mTOR as a central hub of nutrient signalling and cell growth.

Kim J, Guan KL.

Nat Cell Biol. 2019 Jan;21(1):63-71. doi: 10.1038/s41556-018-0205-1. Epub 2019 Jan 2. Review.


Rapid diagnosis of IDH1-mutated gliomas by 2-HG detection with gas chromatography mass spectrometry.

Xu H, Xia YK, Li CJ, Zhang JY, Liu Y, Yi W, Qin ZY, Chen L, Shi ZF, Quan K, Yang ZX, Guan KL, Xiong Y, Ng HK, Ye D, Hua W, Mao Y.

Lab Invest. 2018 Dec 20. doi: 10.1038/s41374-018-0163-z. [Epub ahead of print]


Mechanical properties of the supersonic atmospheric plasma sprayed CaP coating post-processed by a microwave-hydrothermal method.

Su Y, Li K, Guan K, Zhu X, Sun J.

Mater Sci Eng C Mater Biol Appl. 2019 Feb 1;95:49-56. doi: 10.1016/j.msec.2018.10.076. Epub 2018 Oct 23.


The Hippo Pathway: Biology and Pathophysiology.

Ma S, Meng Z, Chen R, Guan KL.

Annu Rev Biochem. 2018 Dec 19. doi: 10.1146/annurev-biochem-013118-111829. [Epub ahead of print]


Determining the Phosphorylation Status of Hippo Components YAP and TAZ Using Phos-tag.

Chen R, Plouffe SW, Guan KL.

Methods Mol Biol. 2019;1893:281-287. doi: 10.1007/978-1-4939-8910-2_21.


Cell type-dependent function of LATS1/2 in cancer cell growth.

Pan WW, Moroishi T, Koo JH, Guan KL.

Oncogene. 2018 Dec 10. doi: 10.1038/s41388-018-0610-8. [Epub ahead of print]


The reduced activity of PP-1α under redox stress condition is a consequence of GSH-mediated transient disulfide formation.

Singh S, Lämmle S, Giese H, Kämmerer S, Meyer-Roxlau S, Alfar EA, Dihazi H, Guan K, El-Armouche A, Richter F.

Sci Rep. 2018 Dec 7;8(1):17711. doi: 10.1038/s41598-018-36267-6.


MFG-E8 induced differences in proteomic profiles in mouse C2C12 cells and its effect on PI3K/Akt and ERK signal pathways.

Li H, Guan K, Li X, Ma Y, Zhou S.

Int J Biol Macromol. 2019 Mar 1;124:681-688. doi: 10.1016/j.ijbiomac.2018.11.265. Epub 2018 Nov 28.


OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ.

Zhang Z, Du J, Wang S, Shao L, Jin K, Li F, Wei B, Ding W, Fu P, van Dam H, Wang A, Jin J, Ding C, Yang B, Zheng M, Feng XH, Guan KL, Zhang L.

Mol Cell. 2019 Jan 3;73(1):7-21.e7. doi: 10.1016/j.molcel.2018.10.030. Epub 2018 Nov 21.


Oncogenic R132 IDH1 Mutations Limit NADPH for De Novo Lipogenesis through (D)2-Hydroxyglutarate Production in Fibrosarcoma Cells.

Badur MG, Muthusamy T, Parker SJ, Ma S, McBrayer SK, Cordes T, Magana JH, Guan KL, Metallo CM.

Cell Rep. 2018 Nov 6;25(6):1680. doi: 10.1016/j.celrep.2018.10.099. No abstract available.


SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response.

Chen LL, Lin HP, Zhou WJ, He CX, Zhang ZY, Cheng ZL, Song JB, Liu P, Chen XY, Xia YK, Chen XF, Sun RQ, Zhang JY, Sun YP, Song L, Liu BJ, Du RK, Ding C, Lan F, Huang SL, Zhou F, Liu S, Xiong Y, Ye D, Guan KL.

Cell Rep. 2018 Nov 6;25(6):1485-1500.e4. doi: 10.1016/j.celrep.2018.10.028.


Sweet sorghum (Sorghum bicolor L.) SbSTOP1 activates the transcription of a β-1,3-glucanase gene to reduce callose deposition under Al toxicity: A novel pathway for Al tolerance in plants.

Gao J, Yan S, Yu H, Zhan M, Guan K, Wang Y, Yang Z.

Biosci Biotechnol Biochem. 2019 Mar;83(3):446-455. doi: 10.1080/09168451.2018.1540290. Epub 2018 Nov 2.


Long-Term Outcome of Dynesys Dynamic Stabilization for Lumbar Spinal Stenosis.

Zhang Y, Zhang ZC, Li F, Sun TS, Shan JL, Guan K, Zhao GM, Zhang LZ.

Chin Med J (Engl). 2018 Nov 5;131(21):2537-2543. doi: 10.4103/0366-6999.244107.


Patch test diagnosis of non-immediate cutaneous reaction to myrrh following oral intake of a traditional Chinese medicine decoction.

Xu YY, Li L, Xuan L, Guan K.

Contact Dermatitis. 2019 Feb;80(2):135-136. doi: 10.1111/cod.13144. Epub 2018 Oct 29. No abstract available.


Oncogenic R132 IDH1 Mutations Limit NADPH for De Novo Lipogenesis through (D)2-Hydroxyglutarate Production in Fibrosarcoma Sells.

Badur MG, Muthusamy T, Parker SJ, Ma S, McBrayer SK, Cordes T, Magana JH, Guan KL, Metallo CM.

Cell Rep. 2018 Oct 23;25(4):1018-1026.e4. doi: 10.1016/j.celrep.2018.09.074. Erratum in: Cell Rep. 2018 Nov 6;25(6):1680.


Defective Mitochondrial Cardiolipin Remodeling Dampens HIF-1α Expression in Hypoxia.

Chowdhury A, Aich A, Jain G, Wozny K, Lüchtenborg C, Hartmann M, Bernhard O, Balleiniger M, Alfar EA, Zieseniss A, Toischer K, Guan K, Rizzoli SO, Brügger B, Fischer A, Katschinski DM, Rehling P, Dudek J.

Cell Rep. 2018 Oct 16;25(3):561-570.e6. doi: 10.1016/j.celrep.2018.09.057.


Regulation of the Hippo Pathway by Phosphatidic Acid-Mediated Lipid-Protein Interaction.

Han H, Qi R, Zhou JJ, Ta AP, Yang B, Nakaoka HJ, Seo G, Guan KL, Luo R, Wang W.

Mol Cell. 2018 Oct 18;72(2):328-340.e8. doi: 10.1016/j.molcel.2018.08.038. Epub 2018 Oct 4.


Sarcoplasmic reticulum calcium leak contributes to arrhythmia but not to heart failure progression.

Mohamed BA, Hartmann N, Tirilomis P, Sekeres K, Li W, Neef S, Richter C, Zeisberg EM, Kattner L, Didié M, Guan K, Schmitto JD, Lehnart SE, Luther S, Voigt N, Seidler T, Sossalla S, Hasenfuss G, Toischer K.

Sci Transl Med. 2018 Sep 12;10(458). pii: eaan0724. doi: 10.1126/scitranslmed.aan0724. Erratum in: Sci Transl Med. 2019 Jan 9;11(474):.


The Molecular Mechanisms of Protective Role of Se on the G0/G1 Phase Arrest Caused by AFB1 in Broiler's Thymocytes.

Guan K, Li H, Zuo Z, Wang F, Hu P, Peng X, Fang J, Cui H, Shu G, Ouyang P.

Biol Trace Elem Res. 2018 Sep 10. doi: 10.1007/s12011-018-1491-y. [Epub ahead of print]


Emergent Life Events: An In-Depth Investigation of Characteristics and Provider Responses during Youth Evidence-Based Treatment.

Guan K, Kim RE, Rodas NV, Brown TE, Gamarra JM, Krull JL, Chorpita BF.

J Clin Child Adolesc Psychol. 2018 Aug 24:1-16. doi: 10.1080/15374416.2018.1496441. [Epub ahead of print]


RAP2 mediates mechanoresponses of the Hippo pathway.

Meng Z, Qiu Y, Lin KC, Kumar A, Placone JK, Fang C, Wang KC, Lu S, Pan M, Hong AW, Moroishi T, Luo M, Plouffe SW, Diao Y, Ye Z, Park HW, Wang X, Yu FX, Chien S, Wang CY, Ren B, Engler AJ, Guan KL.

Nature. 2018 Aug;560(7720):655-660. doi: 10.1038/s41586-018-0444-0. Epub 2018 Aug 22.


Interplay between YAP/TAZ and Metabolism.

Koo JH, Guan KL.

Cell Metab. 2018 Aug 7;28(2):196-206. doi: 10.1016/j.cmet.2018.07.010. Review.


Efficacy of montelukast as prophylactic treatment for seasonal allergic rhinitis.

Li L, Wang R, Cui L, Guan K.

Ear Nose Throat J. 2018 Jul;97(7):E12-E16.


Author Correction: Regulation of Hippo pathway transcription factor TEAD by p38 MAPK-induced cytoplasmic translocation.

Lin KC, Moroishi T, Meng Z, Jeong HS, Plouffe SW, Sekido Y, Han J, Park HW, Guan KL.

Nat Cell Biol. 2018 Sep;20(9):1098. doi: 10.1038/s41556-018-0101-8.


Opposing Tumor-Promoting and -Suppressive Functions of Rictor/mTORC2 Signaling in Adult Glioma and Pediatric SHH Medulloblastoma.

Akgül S, Li Y, Zheng S, Kool M, Treisman DM, Li C, Wang Y, Gröbner S, Ikenoue T, Shen Y, Camelo-Piragua S, Tomasek G, Stark S, Guduguntla V, Gusella JF, Guan KL, Pfister SM, Verhaak RGW, Zhu Y.

Cell Rep. 2018 Jul 10;24(2):463-478.e5. doi: 10.1016/j.celrep.2018.06.050.


Assembly and activation of the Hippo signalome by FAT1 tumor suppressor.

Martin D, Degese MS, Vitale-Cross L, Iglesias-Bartolome R, Valera JLC, Wang Z, Feng X, Yeerna H, Vadmal V, Moroishi T, Thorne RF, Zaida M, Siegele B, Cheong SC, Molinolo AA, Samuels Y, Tamayo P, Guan KL, Lippman SM, Lyons JG, Gutkind JS.

Nat Commun. 2018 Jul 9;9(1):2372. doi: 10.1038/s41467-018-04590-1.


FluoSpec 2-An Automated Field Spectroscopy System to Monitor Canopy Solar-Induced Fluorescence.

Yang X, Shi H, Stovall A, Guan K, Miao G, Zhang Y, Zhang Y, Xiao X, Ryu Y, Lee JE.

Sensors (Basel). 2018 Jun 28;18(7). pii: E2063. doi: 10.3390/s18072063.


Deep phenotyping of human induced pluripotent stem cell-derived atrial and ventricular cardiomyocytes.

Cyganek L, Tiburcy M, Sekeres K, Gerstenberg K, Bohnenberger H, Lenz C, Henze S, Stauske M, Salinas G, Zimmermann WH, Hasenfuss G, Guan K.

JCI Insight. 2018 Jun 21;3(12). pii: 99941. doi: 10.1172/jci.insight.99941. eCollection 2018 Jun 21.


Polycystic kidney disease: a Hippo connection.

Ma S, Guan KL.

Genes Dev. 2018 Jun 1;32(11-12):737-739. doi: 10.1101/gad.316570.118. Review.


YAP and MRTF-A, transcriptional co-activators of RhoA-mediated gene expression, are critical for glioblastoma tumorigenicity.

Yu OM, Benitez JA, Plouffe SW, Ryback D, Klein A, Smith J, Greenbaum J, Delatte B, Rao A, Guan KL, Furnari FB, Chaim OM, Miyamoto S, Brown JH.

Oncogene. 2018 Oct;37(41):5492-5507. doi: 10.1038/s41388-018-0301-5. Epub 2018 Jun 11.


The Hippo pathway effector proteins YAP and TAZ have both distinct and overlapping functions in the cell.

Plouffe SW, Lin KC, Moore JL 3rd, Tan FE, Ma S, Ye Z, Qiu Y, Ren B, Guan KL.

J Biol Chem. 2018 Jul 13;293(28):11230-11240. doi: 10.1074/jbc.RA118.002715. Epub 2018 May 25.


[Effects of double-dose antihistamine or combined therapy in allergic rhinitis].

Li LS, Guan K, Cui L, Wang RQ.

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2018 Jan 5;32(1):27-32. doi: 10.13201/j.issn.1001-1781.2018.01.006. Chinese.


[The clinical value of China Savin pollen extract used for skin prick test].

Guan K, Zhou JX, Wang RQ, Yin J, Wang LL, Zhi YX, Sun JL, Li H, Wen LP, Gu JQ, Tang R, Wang ZX, Li LS, Xu T.

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2018 Feb;32(3):161-166. doi: 10.13201/j.issn.1001-1781.2018.03.001. Chinese.


Satellite sun-induced chlorophyll fluorescence detects early response of winter wheat to heat stress in the Indian Indo-Gangetic Plains.

Song L, Guanter L, Guan K, You L, Huete A, Ju W, Zhang Y.

Glob Chang Biol. 2018 May 10. doi: 10.1111/gcb.14302. [Epub ahead of print]


Precisely Controlling Nanochannels of Graphene Oxide Membranes through Lignin-Based Cation Decoration for Dehydration of Biofuels.

Guan K, Liu Q, Ji Y, Zhang M, Wu Y, Zhao J, Liu G, Jin W.

ChemSusChem. 2018 Jul 20;11(14):2315-2320. doi: 10.1002/cssc.201800479. Epub 2018 May 25.


Incorporating Graphene Oxide into Alginate Polymer with a Cationic Intermediate To Strengthen Membrane Dehydration Performance.

Guan K, Liang F, Zhu H, Zhao J, Jin W.

ACS Appl Mater Interfaces. 2018 Apr 25;10(16):13903-13913. doi: 10.1021/acsami.8b04093. Epub 2018 Apr 10.


MicroRNAs in cardiomyocyte differentiation and maturation.

Alfar EA, El-Armouche A, Guan K.

Cardiovasc Res. 2018 May 1;114(6):779-781. doi: 10.1093/cvr/cvy065. No abstract available.


Identification of STOP1-Like Proteins Associated With Aluminum Tolerance in Sweet Sorghum (Sorghum bicolor L.).

Huang S, Gao J, You J, Liang Y, Guan K, Yan S, Zhan M, Yang Z.

Front Plant Sci. 2018 Feb 28;9:258. doi: 10.3389/fpls.2018.00258. eCollection 2018.


A LATS biosensor screen identifies VEGFR as a regulator of the Hippo pathway in angiogenesis.

Azad T, Janse van Rensburg HJ, Lightbody ED, Neveu B, Champagne A, Ghaffari A, Kay VR, Hao Y, Shen H, Yeung B, Croy BA, Guan KL, Pouliot F, Zhang J, Nicol CJB, Yang X.

Nat Commun. 2018 Mar 13;9(1):1061. doi: 10.1038/s41467-018-03278-w.


The Protective Role of Selenium in AFB1-Induced Tissue Damage and Cell Cycle Arrest in Chicken's Bursa of Fabricius.

Hu P, Zuo Z, Wang F, Peng X, Guan K, Li H, Fang J, Cui H, Su G, Ouyang P, Zhou Y.

Biol Trace Elem Res. 2018 Oct;185(2):486-496. doi: 10.1007/s12011-018-1273-6. Epub 2018 Mar 6.


SIRT5 inhibits peroxisomal ACOX1 to prevent oxidative damage and is downregulated in liver cancer.

Chen XF, Tian MX, Sun RQ, Zhang ML, Zhou LS, Jin L, Chen LL, Zhou WJ, Duan KL, Chen YJ, Gao C, Cheng ZL, Wang F, Zhang JY, Sun YP, Yu HX, Zhao YZ, Yang Y, Liu WR, Shi YH, Xiong Y, Guan KL, Ye D.

EMBO Rep. 2018 May;19(5). pii: e45124. doi: 10.15252/embr.201745124. Epub 2018 Feb 28.


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