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Finding the Pathway: Mediation Analyses in Randomized Controlled Trials.

Localio AR, Meibohm AR, Guallar E.

Ann Intern Med. 2020 Mar 24. doi: 10.7326/M20-0887. [Epub ahead of print] No abstract available.


Studies Using Randomized Trial Data to Compare Nonrandomized Exposures.

Stack CB, Meibohm AR, Liao JM, Guallar E.

Ann Intern Med. 2020 Mar 17. doi: 10.7326/M20-0071. [Epub ahead of print] No abstract available.


Atrial Fibrillation Burden and Subsequent Heart Failure Events In Patients with Cardiac Resynchronization Therapy Devices.

Tanawuttiwat T, Lande J, Smeets P, Gerritse B, Nazarian S, Guallar E, Cheng A.

J Cardiovasc Electrophysiol. 2020 Mar 12. doi: 10.1111/jce.14444. [Epub ahead of print]


Correction: Risk factors control for primary prevention of cardiovascular disease in men: Evidence from the Aragon Workers Health Study (AWHS).

Aguilar-Palacio I, Malo S, Feja C, Lallana M, León-Latre M, Antonio Casasnovas J, Rabanaque M, Guallar E.

PLoS One. 2020 Feb 4;15(2):e0228906. doi: 10.1371/journal.pone.0228906. eCollection 2020.


Use of Gadoxetic Acid-enhanced Liver MRI and Mortality in More than 30 000 Patients with Hepatocellular Carcinoma: A Nationwide Analysis.

Kang TW, Kong SY, Kang D, Kang MW, Kim YK, Kim SH, Sinn DH, Kim YA, Choi KS, Lee ES, Woo SM, Back JH, Guallar E, Cho J.

Radiology. 2020 Apr;295(1):114-124. doi: 10.1148/radiol.2020190639. Epub 2020 Feb 4.


Evaluation of mitochondrial DNA copy number estimation techniques.

Longchamps RJ, Castellani CA, Yang SY, Newcomb CE, Sumpter JA, Lane J, Grove ML, Guallar E, Pankratz N, Taylor KD, Rotter JI, Boerwinkle E, Arking DE.

PLoS One. 2020 Jan 31;15(1):e0228166. doi: 10.1371/journal.pone.0228166. eCollection 2020.


Cyclic Guanosine Monophosphate and Risk of Incident Heart Failure and Other Cardiovascular Events: the ARIC Study.

Zhao D, Guallar E, Vaidya D, Ndumele CE, Ouyang P, Post WS, Lima JA, Ying W, Kass DA, Hoogeveen RC, Shah SJ, Subramanya V, Michos ED.

J Am Heart Assoc. 2020 Jan 21;9(2):e013966. doi: 10.1161/JAHA.119.013966. Epub 2020 Jan 13.


Perceived stress and non-alcoholic fatty liver disease in apparently healthy men and women.

Kang D, Zhao D, Ryu S, Guallar E, Cho J, Lazo M, Shin H, Chang Y, Sung E.

Sci Rep. 2020 Jan 8;10(1):38. doi: 10.1038/s41598-019-57036-z.


Diabetes mellitus is associated with an increased risk of gastric cancer: a cohort study.

Yang HJ, Kang D, Chang Y, Ahn J, Ryu S, Cho J, Guallar E, Sohn CI.

Gastric Cancer. 2019 Dec 18. doi: 10.1007/s10120-019-01033-8. [Epub ahead of print]


Associations Between the Cyclic Guanosine Monophosphate Pathway and Cardiovascular Risk Factors: MESA.

Ying W, Zhao D, Ouyang P, Subramanya V, Vaidya D, Ndumele CE, Guallar E, Sharma K, Shah SJ, Kass DA, Hoogeveen RC, Lima JA, Heckbert SR, deFilippi CR, Post WS, Michos ED.

J Am Heart Assoc. 2019 Dec 17;8(24):e013149. doi: 10.1161/JAHA.119.013149. Epub 2019 Dec 16.


Risk of acute infections in patients with psoriasis: A nationwide population-based cohort study.

Kim BR, Kang D, Kang M, Shim S, Kang CK, Kim DW, Guallar E, Cho J, Youn SW.

J Am Acad Dermatol. 2020 Mar;82(3):764-766. doi: 10.1016/j.jaad.2019.10.072. Epub 2019 Nov 5. No abstract available.


Association of High-Sensitivity Troponin with Cardiac CT Angiography Evidence of Myocardial and Coronary Disease in a Primary Prevention Cohort of Men: Results from MACS.

Rahman F, Zhang Z, Zhao D, Budoff MJ, Palella FJ, Witt MD, Evans RW, Jacobson LP, Korley FK, Guallar E, Post WS, McEvoy JW.

J Appl Lab Med. 2019 Nov;4(3):355-369. doi: 10.1373/jalm.2018.028860. Epub 2019 Apr 23.


Impact of fear of cancer recurrence on survival among lymphoma patients.

Kim SJ, Kang D, Kim IR, Yoon SE, Kim WS, Butow PN, Guallar E, Cho J.

Psychooncology. 2020 Feb;29(2):364-372. doi: 10.1002/pon.5265. Epub 2020 Jan 6.


Mid-life serum Vitamin D concentrations were associated with incident dementia but not late-life neuropsychological performance in the Atherosclerosis Risk in Communities (ARIC) Study.

Fashanu OE, Zhao D, Schneider ALC, Rawlings AM, Sharrett AR, Lutsey PL, Gottesman RF, Gross AL, Guallar E, Alonso A, Mosley TH, Michos ED.

BMC Neurol. 2019 Oct 22;19(1):244. doi: 10.1186/s12883-019-1483-3.


Ambient air pollution as a mediator in the pathway linking race/ethnicity to blood pressure elevation: The multi-ethnic study of atherosclerosis (MESA).

Song L, Smith GS, Adar SD, Post WS, Guallar E, Navas-Acien A, Kaufman JD, Jones MR.

Environ Res. 2020 Jan;180:108776. doi: 10.1016/j.envres.2019.108776. Epub 2019 Sep 30.


Author Correction: Non-alcoholic fatty liver disease and cerebral small vessel disease in Korean cognitively normal individuals.

Jang H, Kang D, Chang Y, Kim Y, Lee JS, Kim KW, Jang YK, Kim HJ, Na DL, Shin HY, Kang M, Guallar E, Cho J, Seo SW.

Sci Rep. 2019 Oct 10;9(1):14825. doi: 10.1038/s41598-019-51401-8.


Resting Heart Rate, Short-Term Heart Rate Variability and Incident Atrial Fibrillation (from the Multi-Ethnic Study of Atherosclerosis (MESA)).

Habibi M, Chahal H, Greenland P, Guallar E, Lima JAC, Soliman EZ, Alonso A, Heckbert SR, Nazarian S.

Am J Cardiol. 2019 Dec 1;124(11):1684-1689. doi: 10.1016/j.amjcard.2019.08.025. Epub 2019 Sep 6.


Risk of chronic obstructive pulmonary disease in healthy individuals with high C-reactive protein levels by smoking status: a population-based cohort study in Korea.

Lim SY, Zhao D, Guallar E, Chang Y, Ryu S, Cho J, Shim JY.

Int J Chron Obstruct Pulmon Dis. 2019 Sep 3;14:2037-2046. doi: 10.2147/COPD.S213665. eCollection 2019.


Weight Change and Development of Subclinical Carotid Atherosclerosis Among Metabolically Healthy Adults: A Cohort Study.

Sinn DH, Kang D, Cho SJ, Chang Y, Ryu S, Song YB, Paik SW, Hong YS, Zhao D, Guallar E, Cho J, Gwak GY.

J Clin Endocrinol Metab. 2020 Mar 1;105(3). pii: dgz040. doi: 10.1210/clinem/dgz040.


Non-alcoholic fatty liver disease and the incidence of myocardial infarction: A cohort study.

Sinn DH, Kang D, Chang Y, Ryu S, Cho SJ, Paik SW, Song YB, Pastor-Barriuso R, Guallar E, Cho J, Gwak GY.

J Gastroenterol Hepatol. 2019 Sep 11. doi: 10.1111/jgh.14856. [Epub ahead of print]


Use of proton pump inhibitors and the risk of cholangitis: a nationwide cohort study.

Min YW, Kang D, Shin JY, Kang M, Park JK, Lee KH, Lee JK, Lee KT, Rhee PL, Kim JJ, Guallar E, Cho J, Lee H.

Aliment Pharmacol Ther. 2019 Oct;50(7):760-768. doi: 10.1111/apt.15466. Epub 2019 Aug 25.


Trace Minerals, Heavy Metals, and Preeclampsia: Findings from the Boston Birth Cohort.

Liu T, Zhang M, Guallar E, Wang G, Hong X, Wang X, Mueller NT.

J Am Heart Assoc. 2019 Aug 20;8(16):e012436. doi: 10.1161/JAHA.119.012436. Epub 2019 Aug 20.


Impact of a topical lotion, CG428, on permanent chemotherapy-induced alopecia in breast cancer survivors: a pilot randomized double-blind controlled clinical trial (VOLUME RCT).

Kang D, Kim IR, Park YH, Im YH, Zhao D, Guallar E, Ahn JS, Cho J.

Support Care Cancer. 2020 Apr;28(4):1829-1837. doi: 10.1007/s00520-019-04982-z. Epub 2019 Jul 23.


Effects of Nutritional Supplements and Dietary Interventions on Cardiovascular Outcomes: An Umbrella Review and Evidence Map.

Khan SU, Khan MU, Riaz H, Valavoor S, Zhao D, Vaughan L, Okunrintemi V, Riaz IB, Khan MS, Kaluski E, Murad MH, Blaha MJ, Guallar E, Michos ED.

Ann Intern Med. 2019 Aug 6;171(3):190-198. doi: 10.7326/M19-0341. Epub 2019 Jul 9.


Long-Term Particulate Matter Exposure and Onset of Depression in Middle-Aged Men and Women.

Zhang Z, Zhao D, Hong YS, Chang Y, Ryu S, Kang D, Monteiro J, Shin HC, Guallar E, Cho J.

Environ Health Perspect. 2019 Jul;127(7):77001. doi: 10.1289/EHP4094. Epub 2019 Jul 3.


Clinical Features and Outcomes of Invasive Breast Cancer: Age-Specific Analysis of a Modern Hospital-Based Registry.

Kim JY, Kang D, Nam SJ, Kim SW, Lee JE, Yu JH, Lee SK, Im YH, Ahn JS, Guallar E, Cho J, Park YH.

J Glob Oncol. 2019 Jul;5:1-9. doi: 10.1200/JGO.19.00034.


Association between aflatoxin-albumin adduct levels and tortilla consumption in Guatemalan adults.

Kroker-Lobos MF, Alvarez CS, Rivera-Andrade A, Smith JW, Egner P, Torres O, Lazo M, Freedman ND, Guallar E, Graubard BI, McGlynn KA, Ramírez-Zea M, Groopman JD.

Toxicol Rep. 2019 May 22;6:465-471. doi: 10.1016/j.toxrep.2019.05.009. eCollection 2019.


Lean non-alcoholic fatty liver disease and development of diabetes: a cohort study.

Sinn DH, Kang D, Cho SJ, Paik SW, Guallar E, Cho J, Gwak GY.

Eur J Endocrinol. 2019 Aug;181(2):185-192. doi: 10.1530/EJE-19-0143.


Changes in acute kidney injury epidemiology in critically ill patients: a population-based cohort study in Korea.

Hwang S, Park H, Kim Y, Kang D, Ku HS, Cho J, Lee JE, Huh W, Guallar E, Suh GY, Jang HR.

Ann Intensive Care. 2019 Jun 7;9(1):65. doi: 10.1186/s13613-019-0534-7.


Endogenous Sex Hormones and Endothelial Function in Postmenopausal Women and Men: The Multi-Ethnic Study of Atherosclerosis.

Mathews L, Subramanya V, Zhao D, Ouyang P, Vaidya D, Guallar E, Yeboah J, Herrington D, Hays AG, Budoff MJ, Michos ED.

J Womens Health (Larchmt). 2019 Jul;28(7):900-909. doi: 10.1089/jwh.2018.7441. Epub 2019 Jun 6.


Age-Specific Distribution of Diagnosis and Outcomes of Children Admitted to ICUs: A Population-Based Cohort Study.

Jung M, Park H, Kang D, Park J, Jeon K, Chung CR, Yang JH, Cho YH, Suh GY, Guallar E, Cho J, Cho J.

Pediatr Crit Care Med. 2019 Jul;20(7):e301-e310. doi: 10.1097/PCC.0000000000001978.


Relationship of the Blood Pressure Categories, as Defined by the ACC/AHA 2017 Blood Pressure Guidelines, and the Risk of  Development of Cardiovascular Disease in Low-Risk Young  Adults: Insights From a Retrospective Cohort of Young Adults.

Kim S, Chang Y, Kang J, Cho A, Cho J, Hong YS, Zhao D, Ahn J, Shin H, Guallar E, Ryu S, Sung KC.

J Am Heart Assoc. 2019 Jun 4;8(11):e011946. doi: 10.1161/JAHA.119.011946. Epub 2019 May 29.


Alcoholic and Nonalcoholic Fatty Liver Disease and Incident Hospitalization for Liver and Cardiovascular Diseases.

Chang Y, Cho J, Cho YK, Cho A, Hong YS, Zhao D, Ahn J, Sohn CI, Shin H, Guallar E, Ryu S.

Clin Gastroenterol Hepatol. 2020 Jan;18(1):205-215.e7. doi: 10.1016/j.cgh.2019.05.004. Epub 2019 May 11.


Biomarkers of Dietary Omega-6 Fatty Acids and Incident Cardiovascular Disease and Mortality.

Marklund M, Wu JHY, Imamura F, Del Gobbo LC, Fretts A, de Goede J, Shi P, Tintle N, Wennberg M, Aslibekyan S, Chen TA, de Oliveira Otto MC, Hirakawa Y, Eriksen HH, Kröger J, Laguzzi F, Lankinen M, Murphy RA, Prem K, Samieri C, Virtanen J, Wood AC, Wong K, Yang WS, Zhou X, Baylin A, Boer JMA, Brouwer IA, Campos H, Chaves PHM, Chien KL, de Faire U, Djoussé L, Eiriksdottir G, El-Abbadi N, Forouhi NG, Michael Gaziano J, Geleijnse JM, Gigante B, Giles G, Guallar E, Gudnason V, Harris T, Harris WS, Helmer C, Hellenius ML, Hodge A, Hu FB, Jacques PF, Jansson JH, Kalsbeek A, Khaw KT, Koh WP, Laakso M, Leander K, Lin HJ, Lind L, Luben R, Luo J, McKnight B, Mursu J, Ninomiya T, Overvad K, Psaty BM, Rimm E, Schulze MB, Siscovick D, Skjelbo Nielsen M, Smith AV, Steffen BT, Steffen L, Sun Q, Sundström J, Tsai MY, Tunstall-Pedoe H, Uusitupa MIJ, van Dam RM, Veenstra J, Monique Verschuren WM, Wareham N, Willett W, Woodward M, Yuan JM, Micha R, Lemaitre RN, Mozaffarian D, Risérus U; Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Fatty Acids and Outcomes Research Consortium (FORCE).

Circulation. 2019 May 21;139(21):2422-2436. doi: 10.1161/CIRCULATIONAHA.118.038908.


Serum Metabolites and Cardiac Death in Patients on Hemodialysis.

Hu JR, Grams ME, Coresh J, Hwang S, Kovesdy CP, Guallar E, Rhee EP, Shafi T.

Clin J Am Soc Nephrol. 2019 May 7;14(5):747-749. doi: 10.2215/CJN.12691018. Epub 2019 Apr 8. No abstract available.


Late presentation of hepatitis B among patients with newly diagnosed hepatocellular carcinoma: a national cohort study.

Sinn DH, Kang D, Kang M, Paik SW, Guallar E, Cho J, Gwak GY.

BMC Cancer. 2019 Mar 29;19(1):286. doi: 10.1186/s12885-019-5508-5.


Non-alcoholic fatty liver disease and cerebral small vessel disease in Korean cognitively normal individuals.

Jang H, Kang D, Chang Y, Kim Y, Lee JS, Kim KW, Jang YK, Kim HJ, Na DL, Shin HY, Kang M, Guallar E, Cho J, Seo SW.

Sci Rep. 2019 Feb 12;9(1):1814. doi: 10.1038/s41598-018-38357-x. Erratum in: Sci Rep. 2019 Oct 10;9(1):14825.


Racial Differences in Sudden Cardiac Death.

Zhao D, Post WS, Blasco-Colmenares E, Cheng A, Zhang Y, Deo R, Pastor-Barriuso R, Michos ED, Sotoodehnia N, Guallar E.

Circulation. 2019 Apr 2;139(14):1688-1697. doi: 10.1161/CIRCULATIONAHA.118.036553. Erratum in: Circulation. 2019 Apr 2;139(14):e837.


Life's Simple 7 Cardiovascular Health Metrics and Progression of Coronary Artery Calcium in a Low-Risk Population.

Kim S, Chang Y, Cho J, Hong YS, Zhao D, Kang J, Jung HS, Yun KE, Guallar E, Ryu S, Shin H.

Arterioscler Thromb Vasc Biol. 2019 Apr;39(4):826-833. doi: 10.1161/ATVBAHA.118.311821.


Association of statin therapy with clinical outcomes in patients with vasospastic angina: Data from Korean health insurance review and assessment service.

Park SJ, Park H, Kang D, Park TK, Park J, Cho J, Chung CR, Jeon K, Guallar E, Cho J, Suh GY, Yang JH.

PLoS One. 2019 Jan 30;14(1):e0210498. doi: 10.1371/journal.pone.0210498. eCollection 2019.


Risk of Diabetes Associated With Cancer Development-In Reply.

Cho J, Kang D, Hwangbo Y, Guallar E.

JAMA Oncol. 2019 Mar 1;5(3):429-430. doi: 10.1001/jamaoncol.2018.6647. No abstract available.


High prevalence of non-alcoholic fatty liver disease and metabolic risk factors in Guatemala: A population-based study.

Rivera-Andrade A, Kroker-Lobos MF, Lazo M, Freedman ND, Smith JW, Torres O, McGlynn KA, Groopman JD, Guallar E, Ramirez-Zea M.

Nutr Metab Cardiovasc Dis. 2019 Feb;29(2):191-200. doi: 10.1016/j.numecd.2018.10.008. Epub 2018 Oct 31.


Body Mass Index From Early-, Mid-, and Older-Adulthood and Risk of Heart Failure and Atherosclerotic Cardiovascular Disease: MESA.

Fliotsos M, Zhao D, Rao VN, Ndumele CE, Guallar E, Burke GL, Vaidya D, Delaney JCA, Michos ED.

J Am Heart Assoc. 2018 Nov 20;7(22):e009599. doi: 10.1161/JAHA.118.009599.


Hepatitis B virus infection and development of chronic kidney disease: a cohort study.

Hong YS, Ryu S, Chang Y, Caínzos-Achirica M, Kwon MJ, Zhao D, Shafi T, Lazo M, Pastor-Barriuso R, Shin H, Cho J, Guallar E.

BMC Nephrol. 2018 Dec 11;19(1):353. doi: 10.1186/s12882-018-1154-4.


GlycA, a novel inflammatory marker, is associated with subclinical coronary disease.

Tibuakuu M, Fashanu OE, Zhao D, Otvos JD, Brown TT, Haberlen SA, Guallar E, Budoff MJ, Palella FJ Jr, Martinson JJ, Akinkuolie AO, Mora S, Post WS, Michos ED.

AIDS. 2019 Mar 1;33(3):547-557. doi: 10.1097/QAD.0000000000002079.


Relation of Elevated Resting Heart Rate in Mid-Life to Cognitive Decline Over 20 Years (from the Atherosclerosis Risk in Communities [ARIC] Study).

Wang S, Fashanu OE, Zhao D, Guallar E, Gottesman RF, Schneider ALC, McEvoy JW, Norby FL, Aladin AI, Alonso A, Michos ED.

Am J Cardiol. 2019 Jan 15;123(2):334-340. doi: 10.1016/j.amjcard.2018.10.013. Epub 2018 Oct 21.


Increased cardiovascular risk in thyroid cancer patients taking levothyroxine: a nationwide cohort study in Korea.

Suh B, Shin DW, Park Y, Lim H, Yun JM, Song SO, Park JH, Cho B, Guallar E.

Eur J Endocrinol. 2019 Jan 1;180(1):11-20. doi: 10.1530/EJE-18-0551.


Synergistic Opportunities in the Interplay Between Cancer Screening and Cardiovascular Disease Risk Assessment: Together We Are Stronger.

Handy CE, Quispe R, Pinto X, Blaha MJ, Blumenthal RS, Michos ED, Lima JAC, Guallar E, Ryu S, Cho J, Kaye JA, Comin-Colet J, Corbella X, Cainzos-Achirica M.

Circulation. 2018 Aug 14;138(7):727-734. doi: 10.1161/CIRCULATIONAHA.118.035516. Review.


Systematic Review for the 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.

Reboussin DM, Allen NB, Griswold ME, Guallar E, Hong Y, Lackland DT, Miller EPR 3rd, Polonsky T, Thompson-Paul AM, Vupputuri S.

Circulation. 2018 Oct 23;138(17):e595-e616. doi: 10.1161/CIR.0000000000000601.


Vitamin D deficiency is associated with inferior survival of patients with extranodal natural killer/T-cell lymphoma.

Kim SJ, Shu C, Ryu KJ, Kang D, Cho J, Ko YH, Lee SY, Guallar E, Zhao W, Kim WS.

Cancer Sci. 2018 Dec;109(12):3971-3980. doi: 10.1111/cas.13844. Epub 2018 Nov 28.

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