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Items: 18


Proteomic analysis of glycosomes from Trypanosoma cruzi epimastigotes.

Acosta H, Burchmore R, Naula C, Gualdrón-López M, Quintero-Troconis E, Cáceres AJ, Michels PAM, Concepción JL, Quiñones W.

Mol Biochem Parasitol. 2019 Apr;229:62-74. doi: 10.1016/j.molbiopara.2019.02.008. Epub 2019 Mar 1.


Characterization of Plasmodium vivax Proteins in Plasma-Derived Exosomes From Malaria-Infected Liver-Chimeric Humanized Mice.

Gualdrón-López M, Flannery EL, Kangwanrangsan N, Chuenchob V, Fernandez-Orth D, Segui-Barber J, Royo F, Falcón-Pérez JM, Fernandez-Becerra C, Lacerda MVG, Kappe SHI, Sattabongkot J, Gonzalez JR, Mikolajczak SA, Del Portillo HA.

Front Microbiol. 2018 Jun 25;9:1271. doi: 10.3389/fmicb.2018.01271. eCollection 2018.


The Aryl Hydrocarbon Receptor Modulates Production of Cytokines and Reactive Oxygen Species and Development of Myocarditis during Trypanosoma cruzi Infection.

Barroso A, Gualdrón-López M, Esper L, Brant F, Araújo RR, Carneiro MB, Ávila TV, Souza DG, Vieira LQ, Rachid MA, Tanowitz HB, Teixeira MM, Machado FS.

Infect Immun. 2016 Sep 19;84(10):3071-82. doi: 10.1128/IAI.00575-16. Print 2016 Oct.


Suppressor of cytokine signaling 2 modulates the immune response profile and development of experimental cerebral malaria.

Brant F, Miranda AS, Esper L, Gualdrón-López M, Cisalpino D, de Souza DDG, Rachid MA, Tanowitz HB, Teixeira MM, Teixeira AL, Machado FS.

Brain Behav Immun. 2016 May;54:73-85. doi: 10.1016/j.bbi.2016.01.002. Epub 2016 Jan 4.


Biogenesis, maintenance and dynamics of glycosomes in trypanosomatid parasites.

Haanstra JR, González-Marcano EB, Gualdrón-López M, Michels PA.

Biochim Biophys Acta. 2016 May;1863(5):1038-48. doi: 10.1016/j.bbamcr.2015.09.015. Epub 2015 Sep 16. Review.


Evolution, dynamics and specialized functions of glycosomes in metabolism and development of trypanosomatids.

Szöör B, Haanstra JR, Gualdrón-López M, Michels PA.

Curr Opin Microbiol. 2014 Dec;22:79-87. doi: 10.1016/j.mib.2014.09.006. Review.


Ubiquitination of the glycosomal matrix protein receptor PEX5 in Trypanosoma brucei by PEX4 displays novel features.

Gualdrón-López M, Chevalier N, Van Der Smissen P, Courtoy PJ, Rigden DJ, Michels PAM.

Biochim Biophys Acta. 2013 Dec;1833(12):3076-3092. doi: 10.1016/j.bbamcr.2013.08.008. Epub 2013 Aug 27.


Glycosomal targets for anti-trypanosomatid drug discovery.

Barros-Alvarez X, Gualdrón-López M, Acosta H, Cáceres AJ, Graminha MA, Michels PA, Concepción JL, Quiñones W.

Curr Med Chem. 2014;21(15):1679-706. Review.


Processing of the glycosomal matrix-protein import receptor PEX5 of Trypanosoma brucei.

Gualdrón-López M, Michels PA.

Biochem Biophys Res Commun. 2013 Feb 1;431(1):98-103. doi: 10.1016/j.bbrc.2012.12.075. Epub 2012 Dec 22.


Translocation of solutes and proteins across the glycosomal membrane of trypanosomes; possibilities and limitations for targeting with trypanocidal drugs.

Gualdrón-López M, Brennand A, Avilán L, Michels PA.

Parasitology. 2013 Jan;140(1):1-20. doi: 10.1017/S0031182012001278. Epub 2012 Aug 23. Review.


Studies on the organization of the docking complex involved in matrix protein import into glycosomes of Trypanosoma brucei.

Verplaetse E, Gualdrón-López M, Chevalier N, Michels PA.

Biochem Biophys Res Commun. 2012 Aug 10;424(4):781-5. doi: 10.1016/j.bbrc.2012.07.035. Epub 2012 Jul 16.


Channel-forming activities in the glycosomal fraction from the bloodstream form of Trypanosoma brucei.

Gualdron-López M, Vapola MH, Miinalainen IJ, Hiltunen JK, Michels PA, Antonenkov VD.

PLoS One. 2012;7(4):e34530. doi: 10.1371/journal.pone.0034530. Epub 2012 Apr 10.


When, how and why glycolysis became compartmentalised in the Kinetoplastea. A new look at an ancient organelle.

Gualdrón-López M, Brennand A, Hannaert V, Quiñones W, Cáceres AJ, Bringaud F, Concepción JL, Michels PA.

Int J Parasitol. 2012 Jan;42(1):1-20. doi: 10.1016/j.ijpara.2011.10.007. Epub 2011 Nov 22. Review.


Stearoyl-CoA desaturase is an essential enzyme for the parasitic protist Trypanosoma brucei.

Alloatti A, Gupta S, Gualdrón-López M, Nguewa PA, Altabe SG, Deumer G, Wallemacq P, Michels PA, Uttaro AD.

Biochem Biophys Res Commun. 2011 Aug 26;412(2):286-90. doi: 10.1016/j.bbrc.2011.07.084. Epub 2011 Jul 28.


Enolase: a key player in the metabolism and a probable virulence factor of trypanosomatid parasites-perspectives for its use as a therapeutic target.

Avilán L, Gualdrón-López M, Quiñones W, González-González L, Hannaert V, Michels PA, Concepción JL.

Enzyme Res. 2011;2011:932549. doi: 10.4061/2011/932549. Epub 2011 Apr 7.


Autophagy in parasitic protists: unique features and drug targets.

Brennand A, Gualdrón-López M, Coppens I, Rigden DJ, Ginger ML, Michels PA.

Mol Biochem Parasitol. 2011 Jun;177(2):83-99. doi: 10.1016/j.molbiopara.2011.02.003. Epub 2011 Feb 21. Review.


Genetic and chemical evaluation of Trypanosoma brucei oleate desaturase as a candidate drug target.

Alloatti A, Gupta S, Gualdrón-López M, Igoillo-Esteve M, Nguewa PA, Deumer G, Wallemacq P, Altabe SG, Michels PA, Uttaro AD.

PLoS One. 2010 Dec 6;5(12):e14239. doi: 10.1371/journal.pone.0014239.


Autophagy in protists.

Duszenko M, Ginger ML, Brennand A, Gualdrón-López M, Colombo MI, Coombs GH, Coppens I, Jayabalasingham B, Langsley G, de Castro SL, Menna-Barreto R, Mottram JC, Navarro M, Rigden DJ, Romano PS, Stoka V, Turk B, Michels PA.

Autophagy. 2011 Feb;7(2):127-58. Epub 2011 Feb 1. Review.

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