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Items: 20


Defining transcriptional signatures of human hair follicle cell states.

Takahashi R, Grzenda A, Allison T, Rawnsley J, Balin SJ, Sabri S, Plath K, Lowry WE.

J Invest Dermatol. 2019 Oct 29. pii: S0022-202X(19)33295-6. doi: 10.1016/j.jid.2019.07.726. [Epub ahead of print]


A Randomized Double-Blind Placebo-Controlled Trial of Combined Escitalopram and Memantine for Older Adults With Major Depression and Subjective Memory Complaints.

Lavretsky H, Laird KT, Krause-Sorio B, Heimberg BF, Yeargin J, Grzenda A, Wu P, Thana-Udom K, Ercoli LM, Siddarth P.

Am J Geriatr Psychiatry. 2019 Aug 22. pii: S1064-7481(19)30474-9. doi: 10.1016/j.jagp.2019.08.011. [Epub ahead of print]


Psychiatric Comorbidity in Moyamoya Disease and Preliminary Guidelines For Treatment.

Richards M, Grzenda A, Nelson E, Gitlin M.

Am J Psychiatry. 2019 Apr 1;176(4):269-274. doi: 10.1176/appi.ajp.2018.18040404. No abstract available.


Mechanisms Underlying the Regulation of HP1γ by the NGF-PKA Signaling Pathway.

Seo S, Mathison A, Grzenda A, Podratz J, Calvo E, Brimijoin S, Windebank A, Iovanna J, Lomberk G, Urrutia R.

Sci Rep. 2018 Oct 10;8(1):15077. doi: 10.1038/s41598-018-33475-y.


The Aurora A-HP1γ pathway regulates gene expression and mitosis in cells from the sperm lineage.

Leonard PH, Grzenda A, Mathison A, Morbeck DE, Fredrickson JR, de Assuncao TM, Christensen T, Salisbury J, Calvo E, Iovanna J, Coddington CC, Urrutia R, Lomberk G.

BMC Dev Biol. 2015 May 29;15:23. doi: 10.1186/s12861-015-0073-x.


Single and combinatorial chromatin coupling events underlies the function of transcript factor Krüppel-like factor 11 in the regulation of gene networks.

Calvo E, Grzenda A, Lomberk G, Mathison A, Iovanna J, Urrutia R.

BMC Mol Biol. 2014 May 25;15:10. doi: 10.1186/1471-2199-15-10.


Role for Krüppel-like transcription factor 11 in mesenchymal cell function and fibrosis.

Mathison A, Grzenda A, Lomberk G, Velez G, Buttar N, Tietz P, Hendrickson H, Liebl A, Xiong YY, Gores G, Fernandez-Zapico M, Larusso NF, Faubion W, Shah VH, Urrutia R.

PLoS One. 2013 Sep 17;8(9):e75311. doi: 10.1371/journal.pone.0075311. eCollection 2013.


Functional impact of Aurora A-mediated phosphorylation of HP1γ at serine 83 during cell cycle progression.

Grzenda A, Leonard P, Seo S, Mathison AJ, Urrutia G, Calvo E, Iovanna J, Urrutia R, Lomberk G.

Epigenetics Chromatin. 2013 Jul 5;6(1):21. doi: 10.1186/1756-8935-6-21.


Epigenetics: a promising paradigm for better understanding and managing pain.

Seo S, Grzenda A, Lomberk G, Ou XM, Cruciani RA, Urrutia R.

J Pain. 2013 Jun;14(6):549-57. doi: 10.1016/j.jpain.2013.01.772. Epub 2013 Apr 19. Review.


Krüppel-like factor 11 regulates the expression of metabolic genes via an evolutionarily conserved protein interaction domain functionally disrupted in maturity onset diabetes of the young.

Lomberk G, Grzenda A, Mathison A, Escande C, Zhang JS, Calvo E, Miller LJ, Iovanna J, Chini EN, Fernandez-Zapico ME, Urrutia R.

J Biol Chem. 2013 Jun 14;288(24):17745-58. doi: 10.1074/jbc.M112.434670. Epub 2013 Apr 15.


A novel role of the Sp/KLF transcription factor KLF11 in arresting progression of endometriosis.

Daftary GS, Zheng Y, Tabbaa ZM, Schoolmeester JK, Gada RP, Grzenda AL, Mathison AJ, Keeney GL, Lomberk GA, Urrutia R.

PLoS One. 2013;8(3):e60165. doi: 10.1371/journal.pone.0060165. Epub 2013 Mar 28.


Functional characterization of EZH2β reveals the increased complexity of EZH2 isoforms involved in the regulation of mammalian gene expression.

Grzenda A, Lomberk G, Svingen P, Mathison A, Calvo E, Iovanna J, Xiong Y, Faubion W, Urrutia R.

Epigenetics Chromatin. 2013 Feb 28;6(1):3. doi: 10.1186/1756-8935-6-3.


Timing and expression of the angiopoietin-1-Tie-2 pathway in murine lung development and congenital diaphragmatic hernia.

Grzenda A, Shannon J, Fisher J, Arkovitz MS.

Dis Model Mech. 2013 Jan;6(1):106-14. doi: 10.1242/dmm.008821. Epub 2012 Aug 23.


Polycomb antagonizes p300/CREB-binding protein-associated factor to silence FOXP3 in a Kruppel-like factor-dependent manner.

Xiong Y, Khanna S, Grzenda AL, Sarmento OF, Svingen PA, Lomberk GA, Urrutia RA, Faubion WA Jr.

J Biol Chem. 2012 Oct 5;287(41):34372-85. doi: 10.1074/jbc.M111.325332. Epub 2012 Aug 15.


Sequence-specific recruitment of heterochromatin protein 1 via interaction with Krüppel-like factor 11, a human transcription factor involved in tumor suppression and metabolic diseases.

Lomberk G, Mathison AJ, Grzenda A, Seo S, DeMars CJ, Rizvi S, Bonilla-Velez J, Calvo E, Fernandez-Zapico ME, Iovanna J, Buttar NS, Urrutia R.

J Biol Chem. 2012 Apr 13;287(16):13026-39. doi: 10.1074/jbc.M112.342634. Epub 2012 Feb 8.


Detailed structural-functional analysis of the Krüppel-like factor 16 (KLF16) transcription factor reveals novel mechanisms for silencing Sp/KLF sites involved in metabolism and endocrinology.

Daftary GS, Lomberk GA, Buttar NS, Allen TW, Grzenda A, Zhang J, Zheng Y, Mathison AJ, Gada RP, Calvo E, Iovanna JL, Billadeau DD, Prendergast FG, Urrutia R.

J Biol Chem. 2012 Mar 2;287(10):7010-25. doi: 10.1074/jbc.M111.266007. Epub 2011 Dec 27.


Polycomb and the emerging epigenetics of pancreatic cancer.

Grzenda A, Ordog T, Urrutia R.

J Gastrointest Cancer. 2011 Jun;42(2):100-11. doi: 10.1007/s12029-011-9262-4. Review.


Sin3: master scaffold and transcriptional corepressor.

Grzenda A, Lomberk G, Zhang JS, Urrutia R.

Biochim Biophys Acta. 2009 Jun-Aug;1789(6-8):443-50. doi: 10.1016/j.bbagrm.2009.05.007. Epub 2009 Jun 6. Review.


Magnetic resonance imaging of major histocompatibility class II expression in the renal medulla using immunotargeted superparamagnetic iron oxide nanoparticles.

Hultman KL, Raffo AJ, Grzenda AL, Harris PE, Brown TR, O'Brien S.

ACS Nano. 2008 Mar;2(3):477-84. doi: 10.1021/nn700400h.


The sunset of somatic genetics and the dawn of epigenetics: a new frontier in pancreatic cancer research.

Lomberk G, Mathison AJ, Grzenda A, Urrutia R.

Curr Opin Gastroenterol. 2008 Sep;24(5):597-602. doi: 10.1097/MOG.0b013e32830b111d. Review.

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